• Title/Summary/Keyword: biology major

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An anatomic study of the zygomaticus major and minor muscles (임상가를 위한 특집 1 - 큰광대근과 작은광대근의 해부학적 연구)

  • Choi, Da-Yae;Hu, Kyung-Seok;Kim, Hee-Jin
    • The Journal of the Korean dental association
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    • v.50 no.10
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    • pp.616-619
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    • 2012
  • The aim of this study was to clarify the arrangement of the zygomaticus major muscle, and to describe morphology of zygomaticus minor muscle. After a detailed dissection, the zygomaticus muscles were observed in 66 embalmed cadavers. It was found that the insertion of zygomaticus major was divided into superficial and deep bands(42/70, 60%). Zygomaticus minor was inserted not only upper lip also alar portion(5/54, 9.2%). The arrangement and insertion patterns of the zygomaticus muscles in this study are expected to provide critical information for understanding or smile pattern and treatment or fold.

Double-stranded RNA Induces Inflammatory Gene Expression in Schwann Cells: Implication in the Wallerian Degeneration

  • Lee, Hyun-Kyoung;Park, Chan-Hee;Choi, Se-Young;Oh, Seog-Bae;Park, Kyung-Pyo;Kim, Joong-Soo;Lee, Sung-Joong
    • The Korean Journal of Physiology and Pharmacology
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    • v.8 no.5
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    • pp.253-257
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    • 2004
  • Schwann cells play an important role in peripheral nerve regeneration. Upon neuronal injury, activated Schwann cells clean up the myelin debris by phagocytosis, and promote neuronal survival and axon outgrowth by secreting various neurotrophic factors. However, it is unclear how the nerve injury induces Schwann cell activation. Recently, it was reported that certain cytoplasmic molecules, which are secreted by cells undergoing necrotic cell death, induce immune cell activation via the toll-like receptors (TLRs). This suggests that the TLRs expressed on Schwann cells may recognize nerve damage by binding to the endogenous ligands secreted by the damaged nerve, thereby inducing Schwann cell activation. Accordingly, this study was undertaken to examine the expression and the function of the TLRs on primary Schwann cells and iSC, a rat Schwann cell line. The transcripts of TLR2, 3, 4, and 9 were detected on the primary Schwann cells as well as on iSC. The stimulation of iSC with poly (I : C), a synthetic ligand for the TLR3, induced the expression of $TNF-{\alpha}$ and RANTES. In addition, poly (I : C) stimulation induced the iNOS expression and nitric oxide secretion in iSC. These results suggest that the TLRs may be involved in the inflammatory activation of Schwann cells, which is observed during Wallerian degeneration after a peripheral nerve injury.

A Study on the Improvement of Curriculum for the Biology Teacher Education Based on Status Survey (생물교사 교육과정 운영의 실태분석과 개선방안)

  • Kim, Young-Soo;Kim, Do-Hee
    • Journal of The Korean Association For Science Education
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    • v.9 no.1
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    • pp.39-52
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    • 1989
  • The purpose of this study is to propose a direction for the improvement of biology teacher education based on the status survey of the biology teacher preparation curriculum and its implementation. The following Improvements in the biolgy teacher training are suggested from this study 1. Biology education courses should be established as a major in the biology teacher preparation program. 2. Biology teacher educators with major in biology education should be employed in all the departments of biology education. 3. The manpower for biology education should be cultivated. 4. The research and development for biology education should be promoted and supported. 5. The biology educators at the biology teacher education program should implement its curriculum with correct and clear understanding of the program purposes in mind.

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Molecular characterization and expression of CD96 in red seabream (Pagrus major)

  • Won-Sik Woo;Kwang-Min Choi;Min-Soo Joo;Gyoungsik Kang;Kyung-Ho Kim;Ha-Jeong Son;Min-Young Sohn;Do-Hyung Kim;Chan-Il Park
    • Fisheries and Aquatic Sciences
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    • v.26 no.2
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    • pp.97-104
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    • 2023
  • CD96 is a membrane-bound receptor discovered in humans in 1992 that is mainly present in natural killer cells and T cells derived from haematopoietic cells and performs immune functions. Based on the sequence of CD96 obtained from red seabream (Pagrus major), phylogenetic analysis with other species, infections of normal fish, Streptococcus iniae and red sea bream iridovirus (RSIV), and expression analysis was conducted using real-time polymerase chain reaction. Phylogenetic analysis showed the highest homology with Sparus aurata, and multiple sequence analysis confirmed the conservation of major domains between different fish species. Normal fish high expression results were confirmed in the head kidney, and spleen, which are the haematopoietic organs of the fish. High expression levels were confirmed in the gills, liver, spleen, and kidney on day three after RSIV infection. After S. iniae infection, high expression was confirmed in the gills and liver on day one, and high expression was confirmed in the spleen from 12 hours. These results show that PmCD96 functions as an immune gene in P. major and is considered a basic research case for CD96 in fish's hematopoietic organ immune system.