• Title/Summary/Keyword: biological sensitivity

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Individual-Based Models Applied to Species Abundance Patterns in Benthic Macroinvertebrate Communities in Streams in Response to Pollution

  • Cho, Woon-Seok;Nguyen, Tuyen Van;Chon, Tae-Soo
    • Korean Journal of Ecology and Environment
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    • v.45 no.4
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    • pp.420-443
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    • 2012
  • An Individual-Based Model (IBM) was developed by employing natural and toxic survival rates of individuals to elucidate the community responses of benthic macroin-vertebrates to anthropogenic disturbance in the streams. Experimental models (dose-response and relative sensitivity) and mathematical models (power law and negative exponential distribution) were applied to determinate the individual survival rates due to acute toxicity in stressful conditions. A power law was additionally used to present the natural survival rate. Life events, covering movement, exposure to contaminants, death and reproduction, were simulated in the IBM at the individual level in small (1 m) and short (1 week) scales to produce species abundance distributions (SADs) at the community level in large (5 km) and long (1~2 years) scales. Consequently, the SADs, such as geometric series, log-series, and log-normal distribution, were accordingly observed at severely (Biological Monitoring Working Party (BMWP<10), intermediately (BMWP<40) and weakly (BMWP${\geq}50$) polluted sites. The results from a power law and negative exponential distribution were suitably fitted to the field data across the different levels of pollution, according to the Kolmogorov-Smirnov test. The IBMs incorporating natural and toxic survival rates in individuals were useful for presenting community responses to disturbances and could be utilized as an integrative tool to elucidate community establishment processes in benthic macroin-vertebrates in the streams.

Computer Simulation for Effects of Scintillator and Parallel Hole Collimator on Gamma Probe Imaging (섬광체와 평행구멍조준기가 감마프로브 영상에 미치는 영향에 관한 컴퓨터 시뮬레이션)

  • Bong, Jeong-Gyun;Kim, Hui-Jung;Lee, Jong-Du;Gwon, Su-Il
    • Journal of Biomedical Engineering Research
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    • v.19 no.6
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    • pp.563-570
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    • 1998
  • The purpose of this study was to investigate the effects of scintillator and collimator parameters that tradeoff between system sensitivity and spatial resolution. The parameters simulated using Monte Carlo program were scintillator thickness, colimator hole shape, septal thickness, and hole length. The results show that the sensitivity increases exponentially upto about 1 cm of scintillator thickness as the thickness increases. However the sensitivity is almost constant when the scintiallator is thicker than about 1 cm. The simulation of collimator hole shape shows that the hexagonal hole gives the best spatial resolution for the same system sensitivity. The system statical resolution is improved, as both collimator septal thickness and hole length increase, however that system sensitivity is rapidly decreased. In conclusion, The optimization of scintillator and collimator parameters using monte carlo simulation may be useful to develop a high-resolution miniature gamma probe.

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Sensitivity Enhancement of Polyaniline Sensor to Volatile Organic Compounds (휘발성유기화합물가스에 대한 폴리아닐린 센서의 감도 향상)

  • Yu, Joon-Boo;Liu, Fei;Lim, Jeong-Ok;Byun, Hyung-Gi;Huh, Jeung-Soo
    • Korean Journal of Materials Research
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    • v.17 no.8
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    • pp.433-436
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    • 2007
  • Nano-structured polyaniline have been synthesized by interfacial polymerization method at room temperature. An aqueous solution of aniline in chloroform and another solution of ammonium peroxydisulfate in doping acid were prepared at different times terminated with methanol at room temperature. SEM, UV-vis were used to characterize the polyaniline with regard to their morphology and structure. The diameter and length of polyaniline can be controlled by the reaction time. Nano-structured polyaniline were found to have superior sensitivity for volatile organic compounds(VOCs). As the reaction time to increase from 30minute to 2hours the sensitivity were decreased to VOCs vapors. The sensitivity of Nano-structured polyaniline sensor appeared to VOCs better than the sensitivity of chemical synthesis sensors. The sensitivity of Nano-structured polyaniline sensor improved benzene vapors.

Studies on Sensory Evaluation -[Part II] Trio Paired Comparison- (관능검사(官能檢査)에 관(關)한 연구(硏究) -[제2보(第2報)] 3각1대비교법(3角1對比較法)에 대하여-)

  • Hong, Jin
    • Applied Biological Chemistry
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    • v.20 no.3
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    • pp.270-278
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    • 1977
  • In case of sensory evaluation with multi-samples and long-period, in spite of using method with good sensitivity, quality differences among samples could net be detected well because of panel's fatigue and tiredness. So new method to reduce panel's sense of psychological and physiological responsibility, "Trio Paired Comparison", is designed, and New Modified Scheffe's Method 2 as the statistical method for a test of "Trio Paired Comparison" is proposed. And also in this paper problems and countermeasures in applicating "Trio Paired Comparison" are considered.

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Ability of Facial Affect Perception in Patients with Schizophrenia (정신분열병 환자의 안면 표정 인식 능력)

  • Im, Woo-Young;Oh, Seong-Hee;Lee, Seung-Hwan;Park, Young-Min;Bae, Seong-Man
    • Korean Journal of Biological Psychiatry
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    • v.15 no.3
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    • pp.211-218
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    • 2008
  • Objectives : The purpose of this study is to compare the ability of facial affect perception among schizophrenia patients, their first degree relatives, and normal control subjects. Methods : Thirty five patients with schizophrenia, 22 first degree relatives, and 34 normal control subjects were recruited in this study. All three groups were matched for age and education levels. The facial affect identification test(FAIT), and neurocognitive test were applied. In the FAIT, the correct response rate, perceived intensity, and sensitivity for 6 kinds of affects were compared among three groups. Results : We found that correct response rate of sadness and anger were decreased in the schizophrenia patients compared with the normal control group. Also the schizophrenia patients showed reduced sensitivity for all six affects compared with the normal control group. The ability of facial affect perception in first degree relatives of schizophrenia patients was decreased but there were not any significant differences compared with normal control group. Conclusion : This study confirmed significantly reduced ability of facial affect perception in schizophrenia patients compared with normal control. Decreased ability of facial affect perception in first degree relatives suggests that affective sensitivity can be influenced by genetic predisposition.

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Effects of Expert-Determined Reference Standards in Evaluating the Diagnostic Performance of a Deep Learning Model: A Malignant Lung Nodule Detection Task on Chest Radiographs

  • Jung Eun Huh; Jong Hyuk Lee;Eui Jin Hwang;Chang Min Park
    • Korean Journal of Radiology
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    • v.24 no.2
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    • pp.155-165
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    • 2023
  • Objective: Little is known about the effects of using different expert-determined reference standards when evaluating the performance of deep learning-based automatic detection (DLAD) models and their added value to radiologists. We assessed the concordance of expert-determined standards with a clinical gold standard (herein, pathological confirmation) and the effects of different expert-determined reference standards on the estimates of radiologists' diagnostic performance to detect malignant pulmonary nodules on chest radiographs with and without the assistance of a DLAD model. Materials and Methods: This study included chest radiographs from 50 patients with pathologically proven lung cancer and 50 controls. Five expert-determined standards were constructed using the interpretations of 10 experts: individual judgment by the most experienced expert, majority vote, consensus judgments of two and three experts, and a latent class analysis (LCA) model. In separate reader tests, additional 10 radiologists independently interpreted the radiographs and then assisted with the DLAD model. Their diagnostic performance was estimated using the clinical gold standard and various expert-determined standards as the reference standard, and the results were compared using the t test with Bonferroni correction. Results: The LCA model (sensitivity, 72.6%; specificity, 100%) was most similar to the clinical gold standard. When expert-determined standards were used, the sensitivities of radiologists and DLAD model alone were overestimated, and their specificities were underestimated (all p-values < 0.05). DLAD assistance diminished the overestimation of sensitivity but exaggerated the underestimation of specificity (all p-values < 0.001). The DLAD model improved sensitivity and specificity to a greater extent when using the clinical gold standard than when using the expert-determined standards (all p-values < 0.001), except for sensitivity with the LCA model (p = 0.094). Conclusion: The LCA model was most similar to the clinical gold standard for malignant pulmonary nodule detection on chest radiographs. Expert-determined standards caused bias in measuring the diagnostic performance of the artificial intelligence model.

Characteristics of soil respiration temperature sensitivity in a Pinus/Betula mixed forest during periods of rising and falling temperatures under the Japanese monsoon climate

  • Oe, Yusuke;Yamamoto, Akinori;Mariko, Shigeru
    • Journal of Ecology and Environment
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    • v.34 no.2
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    • pp.193-202
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    • 2011
  • We studied temperature sensitivity characteristics of soil respiration during periods of rising and falling temperatures within a common temperature range. We measured soil respiration continuously through two periods (a period of falling temperature, from August 7, 2003 to October 13, 2003; and a period of rising temperature from May 2, 2004 to July 2, 2004) using an open-top chamber technique. A clear exponential relationship was observed between soil temperature and soil respiration rate during both periods. However, the effects of soil water content were not significant, because the humid monsoon climate prevented soil drought, which would otherwise have limited soil respiration. We analyzed temperature sensitivity using the $Q_{10}$ value and $R_{ref}$ (reference respiration at the average temperature for the observation period) and found that these values tended to be higher during the period of rising temperature than during the period of falling temperature. In the absence of an effect on soil water content, several other factors could explain this phenomenon. Here, we discuss the factors that control temperature sensitivity of soil respiration during periods of rising and falling temperature, such as root respiration, root growth, root exudates, and litter supply. We also discuss how the contribution of these factors may vary due to different growth states or due to the effects of the previous season, despite a similar temperature range.

Rheological perspectives of industrial coating process

  • Kim, Sun-Hyung;Kim, Jae-Hong;Ahn, Kyung-Hyun;Lee, Seung-Jong
    • Korea-Australia Rheology Journal
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    • v.21 no.2
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    • pp.83-89
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    • 2009
  • Coating process plays an important role in information technology such as display, battery, chip manufacturing and so on. However, due to complexity of coating material and fast deformation of the coating flow, the process is hard to control and it is difficult to maintain the desired quality of the products. Moreover, it is hard to measure the coating process because of severe processing conditions such as high drying temperature, high deformation coating flow, and sensitivity to the processing variables etc. In this article, the coating process is to be re-illuminated from the rheological perspectives. The practical approach to analyze and quantify the coating process is discussed with respect to coating materials, coating flow and drying process. The ideas on the rheology control of coating materials, pressure and wet thickness control in patch coating process, and stress measurement during drying process will be discussed.

Screening of Genes Related to Methylglyoxal Susceptibility

  • Kim, In-Sook;Kim, Joon-Ho;Min, Bum-Chan;Lee, Chang-Han;Park, Chan-Kyu
    • Journal of Microbiology
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    • v.45 no.4
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    • pp.339-343
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    • 2007
  • Methylglyoxal (MG) is a reactive metabolite known to accumulate in certain physiological conditions. We attempted to isolate genes associated with this metabolite by genome-wide mutagenesis with TnphoA derivative. After screening on methylglyoxal-containing plate, we obtained insertions in three different genes, ydbD, yjjQ, and yqiI, which gave rise to reproducible MG-sensitive phenotypes in glyoxalase-deficient strain. In addition to its MG sensitivity, the insertion in yqiI exhibited an impaired motility resulting from a reduced flagellar expression.

Serological Identification of Mastitic Streptococci by Lancefield Grouping and Antibiotic Sensitivity Test (Lancefield Grouping에 의한 유방염유래(乳房炎由來) Streptococcus의 동정(同定)과 항생물질(抗生物質)에 대한 감수성조사(感受性調査))

  • Seok, Ho Bong;Lee, Hyun Soo
    • Korean Journal of Veterinary Research
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    • v.15 no.1
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    • pp.69-73
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    • 1975
  • A Total of 173 streptococci isolated from 536 dairy cattle in Gyeonggi Province identified by Lancefield serological reaction and other biological properties. Antibiotics sensitivity test was also examined and the results obtained were as follows: 1. A total of 173 isolates of 167 strains (96.5%) were reacted with group A,B,C,D,E and G antisera. 2. Of the 167 positive strains, 75 strains were identified to Streptooccus uberis, 56 to Streptococcus agalactiage and 26 to Streptococcus dysgactiae, respectively. Also, Sreptococcus pyogenes, group D and group G streptococci were rarely isolated. 3. In results of antibiotic sensitivity tests, the most isolates were sensitive to leucomycin and erythromycin but less sensitive to streptomycin. and kanamycin.

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