• Title/Summary/Keyword: biological sensitivity

Search Result 584, Processing Time 0.025 seconds

Morphology, Molecular Phylogeny, and Fungicide Sensitivity of Phytophthora nagaii and P. tentaculata in Korea

  • Seung Hyun Lee;Bora Nam;Dong Jae Lee;Young-Joon Choi
    • Mycobiology
    • /
    • v.51 no.5
    • /
    • pp.333-342
    • /
    • 2023
  • Phytophthora species, classified under Oomycota, cause significant damage to various crops and trees. The present study introduced Phytophthora species, P. nagaii and P. tentaculata, new to Korea, which pose notable risks to their respective host plants. Our research provided a comprehensive description of these species taking into account their cultural features, morphological characteristics, and molecular phylogenetic analysis using the internal transcribed spacer rDNA region and cytochrome c oxidase subunit mtDNA genes (cox1 and cox2) sequences. In addition, this study first evaluated the sensitivity of P. nagaii and P. tentaculata to five anti-oomycete fungicides, finding both species most responsive to picarbutrazox and P. tentaculata resistant to fluazinam. The data can guide targeted treatment strategies and offer insights into effective control methods. The findings expand our understanding of the diversity, distribution, and management of Phytophthora species in Korea.

Design of Implantable Microphone for Artificial Middle Ear System

  • Kim Min-Kyu;Lim Hyung-Gyu;Yoon Young-Ho;Lee Jyung-Hyun;Park Il-Yong;Song Byung-Seop;Kim Myoung-Nam;Cho Jin-Ho
    • Journal of Biomedical Engineering Research
    • /
    • v.26 no.3
    • /
    • pp.139-144
    • /
    • 2005
  • An implantable microphone that can be utilized as part of a totally implantable hearing aid is designed and implemented. The proposed microphone is implanted in the center of the pinna, and designed to ensure the speech frequency range and the appropriate sensitivity. The characteristics of the proposed microphone are evaluated using a finite element analysis (FEA). The microphone is composed of a small electric condenser microphone, titanium case 6.2mm in diameter and 3mm high, and $10{\mu}m$ SUS316L vibrating membrane in contact with hypodermic tissue to maintain the sensitivity of the microphone. The microphone components are all made of biocompatible materials, then the assembled microphone is hermetically sealed using a polymer and ceramic. Experiments with the fabricated microphone confirm an operational bandwidth of up to 5kHz without any decline of sensitivity in 6mm of hypodermic tissue.

Development of Benthic Macroinvertebrates Family-Level Biotic Index for Biological Assessment on Korean Stream Environment (한국의 하천환경 평가를 위한 저서성 대형무척추동물의 과 범주 생물지수 개발)

  • Kong, Dongsoo;Min, Jeong-Ki;Noh, Seong-Yoo
    • Journal of Korean Society on Water Environment
    • /
    • v.35 no.2
    • /
    • pp.152-164
    • /
    • 2019
  • In this study, a Benthic Macroinvertebrates Family Index (BMFI) was developed using 100 indicator groups (99 families including Chironomidae with 2 phena). Families were assigned a score between 1 and 10 depending on their sensitivity to organic pollution. The BMFI was composed of the sensitivity and relative abundance of the indicator taxa. Sensitivity values of each group were generally similar to Biological Monitoring Working Party (BMWP) scores or Walley, Hawkes, Paisley, Trigg (WHPT) scores of UK, Japanese BMWP scores, and the FBI tolerance values of North America. However, sensitivity values of some taxa were significantly different from those of foreign countries, which seemed to have resulted from discrepancy in species composition, difference of taxonomic classification system, or methodological difference for estimation of sensitivity. As an annual average level, BMFI showed significant correlation with concentration of 5-day biochemical oxygen demand (BOD5) (correlation coefficient r = -0.80, n = 569 sites), total suspended solids (r = -0.68), and total phosphorus (r = -0.79). In addition, BMFI revealed strong correlation with Shannon-Weaver's species diversity (r = 0.85), Margalef's species richness (r = 0.85) and McNaughton's dominance (r = -0.84). Correlation between BMFI and water quality parameters or community indices such as species diversity did not show significant difference compared to that of species-level indices such as BMI (Benthic Macroinvertebrates Index). This means that BMFI is a more useful indicator in terms of easy identification of organisms. BMFI was used to assess the environmental status of 3,017 sites of Stream Ecosystem Survey conducted by the Korean Ministry of Environment between 2016 and 2018. As a result, about half of all sites appeared to be in good condition, and a quarter in poor condition.

Design and Implementation of Optimal LED Emotional-Lighting Control System (최적의 LED 감성조명 제어 시스템 설계 및 구현)

  • Yun, Su-Jeong;Lin, Chi-Ho
    • The Journal of Korean Institute of Communications and Information Sciences
    • /
    • v.40 no.8
    • /
    • pp.1637-1642
    • /
    • 2015
  • Next-generation applications using technology IT fused to biological signals from the emotional state to extract a lot of research has been, and the sensitivity of the human sensory functions influences the physiological condition known to be the fact that. In this paper, Propose an Emotional-lighting control algorithm using bio-signals. LED lighting for Emotion light is environmentally friendly and has a high efficiency and long life. In particular, LED lights are different colors represent the possible single light sphere advantages. And, Human sensitivity for determining a more accurate biological signals using EEG was collected using EEG equipment sensitivity was determined to analyze the EEG.

Isolation and Characterization of DNA Damaging Agent Sensitivity of rqh1 mutant from Schizosaccharomyce pombe (분열형 효모인 Schizosaccharomyces pombe 로부터 rqh1 돌연변이의 DNA damaging agent sensitivity를 보상하는 유전자의 특성 연구)

  • Lee, In-Hye;Choi, In-Soon
    • Journal of Life Science
    • /
    • v.17 no.1 s.81
    • /
    • pp.39-44
    • /
    • 2007
  • The Rqh1 gene is essential for vegetative growth in fission Yeast. The rqh1 mutant showed that sensitivity of DNA damaging agent, a wild range of phenotype including abnormal gene expression and cell elongation. This result showed that the rqhl-overexpression cell was sensitivity to DNA damaging agent like rqhl mutant. When Rqh1 have an over-expression by $nmt1^+$ promoter of pREP vector, rqh1 mutant DNA damaging agent sensitivity could be compensated. We isolated two strong mutant containing complementation gene, rqh156 and rqh172, respectively. This result observed that the DNA damaging agent sensitivity of rqhl mutant was complemented by the expression of rqh156 and rqh172. They induced mRNA expression in a dose-dependent manner HU, MMS and UV. The HU sensitivity of the rqhl was complemented by the expression of rqh156 and rqh172. The mRNA expression of rqh156 decreased on HU dose dependent but the mRNA expression of rqh172 did not decrease on HU dose dependent. The MMS and W sensitivity of the rqhl was complemented by the expression of rqh156 and rqh172. These results indicate that the isolated rqhl gene may play an important role in DNA metabolism.

KNOCKDOWN OF IGF-1R BY ANTISENSE OLIGODEOXYNUCLEOTIDE AUGUMENTS THE SENSITIVITY OF BLADDER CANCER CELLS TO MMC

  • Wu, Shu-Fang;Sun, Hong-Zhi;Tu, Zeng-Hong
    • Proceedings of the Korean Society of Toxicology Conference
    • /
    • 2001.10a
    • /
    • pp.203-204
    • /
    • 2001
  • Background and Aim: Transitional cell carcinoma (TCC) of the bladder represents the fifth most prevalent malignancy in Western population, with peak incidence found in males of the 50- to 70-year-old age group. A major problem in the management of bladder cancer is the low sensitivity of a large proportion (approximately 40%) among bladder tumors to chemotherapy and the high risk for recurrence of bladder tumors after transurethral resection.(omitted)

  • PDF

High-sensitivity NIR Sensing with Stacked Photodiode Architecture

  • Hyunjoon Sung;Yunkyung Kim
    • Current Optics and Photonics
    • /
    • v.7 no.2
    • /
    • pp.200-206
    • /
    • 2023
  • Near-infrared (NIR) sensing technology using CMOS image sensors is used in many applications, including automobiles, biological inspection, surveillance, and mobile devices. An intuitive way to improve NIR sensitivity is to thicken the light absorption layer (silicon). However, thickened silicon lacks NIR sensitivity and has other disadvantages, such as diminished optical performance (e.g. crosstalk) and difficulty in processing. In this paper, a pixel structure for NIR sensing using a stacked CMOS image sensor is introduced. There are two photodetection layers, a conventional layer and a bottom photodiode, in the stacked CMOS image sensor. The bottom photodiode is used as the NIR absorption layer. Therefore, the suggested pixel structure does not change the thickness of the conventional photodiode. To verify the suggested pixel structure, sensitivity was simulated using an optical simulator. As a result, the sensitivity was improved by a maximum of 130% and 160% at wavelengths of 850 nm and 940 nm, respectively, with a pixel size of 1.2 ㎛. Therefore, the proposed pixel structure is useful for NIR sensing without thickening the silicon.

Comparative Study of the Difference in Behavior of the Accessory Gene Regulator (Agr) in USA300 and USA400 Community-Associated Methicillin-Resistant Staphylococcus aureus (CA-MRSA)

  • Lee, Hye Soo;Song, Hun-Suk;Lee, Hong-Ju;Kim, Sang Hyun;Suh, Min Ju;Cho, Jang Yeon;Ham, Sion;Kim, Yun-Gon;Joo, Hwang-Soo;Kim, Wooseong;Lee, Sang Ho;Yoo, Dongwon;Bhatia, Shashi Kant;Yang, Yung-Hun
    • Journal of Microbiology and Biotechnology
    • /
    • v.31 no.8
    • /
    • pp.1060-1068
    • /
    • 2021
  • Community-associated Methicillin-Resistant Staphylococcus aureus (CA-MRSA) is notorious as a leading cause of soft tissue infections. Despite several studies on the Agr regulator, the mechanisms of action of Agr on the virulence factors in different strains are still unknown. To reveal the role of Agr in different CA-MRSA, we investigated the LACΔagr mutant and the MW2Δagr mutant by comparing LAC (USA300), MW2 (USA400), and Δagr mutants. The changes of Δagr mutants in sensitivity to oxacillin and several virulence factors such as biofilm formation, pigmentation, motility, and membrane properties were monitored. LACΔagr and MW2Δagr mutants showed different oxacillin sensitivity and biofilm formation compared to the LAC and MW2 strains. Regardless of the strain, the motility was reduced in Δagr mutants. And there was an increase in the long chain fatty acid in phospholipid fatty acid composition of Δagr mutants. Other properties such as biofilm formation, pigmentation, motility, and membrane properties were different in both Δagr mutants. The Agr regulator may have a common role like the control of motility and straindependent roles such as antibiotic resistance, biofilm formation, change of membrane, and pigment production. It does not seem easy to control all MRSA by targeting the Agr regulator only as it showed strain-dependent behaviors.

A STATISTICAL DESIGN OF SENSITIVITY EXPERIMENTS

  • Lee, Chun-Jin
    • Journal of applied mathematics & informatics
    • /
    • v.6 no.2
    • /
    • pp.631-638
    • /
    • 1999
  • Sensitive testing has been widely employed for many years in connection with the development and evaluation explosives detonation devices and propellants. Perhaps its earliest and possibly most important implementation was in biological studies of dosage mortality and response to drugs. Recently sensitivity experiments has been employed in the evaluation of new materials subject to stress in various environments and in delineanation of unstable combustion regions in chemical propulsion systems. This paper discussed a sta-tistical development of sensitivity testing.