• Title/Summary/Keyword: biological mimic

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Human Body Orientation Tracking System Using Inertial and Magnetic Sensors (관성 센서와 지자계 센서를 사용한 인체 방향 추적 시스템)

  • Choi, H.R.;Ryu, M.H.;Yang, Y.S.
    • Journal of Biomedical Engineering Research
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    • v.32 no.2
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    • pp.118-126
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    • 2011
  • This study proposes a human body orientation tracking system by inertial and earth magnetic sensors. These sensors were fused by indirect Kalman filter. The proposed tracking system was configured and the filter was implemented. The tracking performance was evaluated with static and dynamic tests. In static test, the sensor was fixed on the floor while its static characteristics was analyzed. In dynamic test, the sensor was held and moved manually for 30 seconds. The dynamic test included x, y, z axis rotations, and elbow flection/extension motions that mimic drinking. For these dynamic motions, the tracking angle error was under $4.1^{\circ}$ on average. The proposed tracking method is expected to be useful for various human body motion analysis.

An Overview of Laser-assisted Bioprinting (LAB) in Tissue Engineering Applications

  • Ventura, Reiza Dolendo
    • Medical Lasers
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    • v.10 no.2
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    • pp.76-81
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    • 2021
  • Biological tissues and organs are composed of different arrays of cells, biochemical cues, and extracellular matrices arranged in a complex microarchitecture. Laser-Assisted Bioprinting (LAB) is an emerging and promising technology that is reproducible with high accuracy that can be used for fabricating complex bioengineered scaffolds that mimic tissues and organs. The LAB process allows researchers to print intricate structural scaffolds using cells and different biomaterials essential for facilitating cell-scaffold interaction and to induce tissue and organ regeneration which cannot be achieved in a traditional scaffold fabrication. This process can fabricate artificial cell niches or architecture without affecting cellular viability and material integrity. This review tackles the basic principles and key aspects of Laser-Assisted Bioprinting. Recent advances, limitations, and future perspectives are also discussed.

Utilizing Optical Phantoms for Biomedical-optics Technology: Recent Advances and Challenges

  • Ik Hwan Kwon;Hoon-Sup Kim;Do Yeon Kim;Hyun-Ji Lee;Sang-Won Lee
    • Current Optics and Photonics
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    • v.8 no.4
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    • pp.327-344
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    • 2024
  • Optical phantoms are essential in optical imaging and measurement instruments for performance evaluation, calibration, and quality control. They enable precise measurement of image resolution, accuracy, sensitivity, and contrast, which are crucial for both research and clinical diagnostics. This paper reviews the recent advancements and challenges in phantoms for optical coherence tomography, photoacoustic imaging, digital holographic microscopy, optical diffraction tomography, and oximetry tools. We explore the fundamental principles of each technology, the key factors in phantom development, and the evaluation criteria. Additionally, we discuss the application of phantoms used for enhancing optical-image quality. This investigation includes the development of realistic biological and clinical tissue-mimicking phantoms, emphasizing their role in improving the accuracy and reliability of optical imaging and measurement instruments in biomedical and clinical research.

Development of Vegetable Alternative Materials for Mink Oil (밍크 오일의 식물성 대체원료 개발)

  • Seok-Ju Lee;Min-Tae Kim;So Min Lee;So Young Jung;Sofia Brito;Hyojin Heo;Byungsun Cha;Sang Hun Lee;Lei Lei;Ha Hyeon Jo;You-Yeon Chun;Ye Ji Kim;Mi-Gi Lee;Byeong-Mun Kwak;Bum-Ho Bin
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.49 no.1
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    • pp.1-8
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    • 2023
  • This study focused on the development of a vegetable recombinated oil to mimic the animal-derived mink oil. Various vegetable oils and fatty acid substrates were mixed and an immobilized enzyme was utilized in the reaction to synthesize a plant-derived mink oil through deacidification and purification processes. The chemical composition and thermal properties of the recombined oil were confirmed using gas chromatography and differential scanning calorimetry. Our results show a high similarity between mink oil and our synthesized plant-derived mink oil, revealing the potential of utilizing vegetable alternatives for the substitution of animal raw materials, which have been gradually discontinued as cosmetic ingredients.

Distribution of Procymidone in a Small Vinyl House after Application of Smoke Generator (소형 비닐하우스 내에서 훈연처리된 살균제 Procymidone의 분포 특성)

  • Lim, He-Kyoung;Kim, Joung-Han;Cho, Kwang-Yun;Yu, Ju-Hyun
    • Applied Biological Chemistry
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    • v.44 no.1
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    • pp.7-11
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    • 2001
  • The distribution of procymidone in a small vinyl house containing cucumber plants or mimic plants was investigated after application of smoke generator. The deposition of procymidone on glass plate and filter paper was significantly similar to that on cucumber leaves, so that glass plate and filter paper could be substituted for cucumber leaves on deposition studies. The deposition of procymidone was proportional to the horizontally projected area of surface; the deposition on the horizontal surface was maximal, and the deposition was minimal for the perpendicular surface. The amount of deposition on the backside of leaf was less than 5% compared to that on the horizontal surface of leaf. The height of leaf from the floor was not a significant factor influencing on the deposition of procymidone whether leaves were overlapped or not. However, the deposition of procymidone on the overlapped leaves was relatively less than that on the unoverlapped leaves. And the deposition difference depending on the distance between leaves was not observable. Overall, the deposition of procymidone was proportionally increased with the application rate of smoke generator, but the deposition was inversely related to the sum of the total horizontal leaf area of mimic plants and the surface area of floor.

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Spatio-temporal Distribution Pattern of New Biotypes of Weedy Rice (Oryza sativa L.) in Selangor North-West Project, Malaysia

  • Baki, B.B.;M.M., Shakirin
    • Korean Journal of Weed Science
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    • v.30 no.2
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    • pp.68-83
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    • 2010
  • Weedy rice (Oryza sativa L.) occurred sympatrically with other weeds and the rice crop in Malaysian rice granaries. We conducted field surveys in 2006-2008 seasons in 7 farm blocks of Selangor's North West Project, Malaysia to enlist the new biotypes of weedy rice (NBWR) and assess their spatio-temporal pattern of distribution based on quantitative and dispersion indices. No less than 16 accessions of NBWR were identified based on their special traits, viz. panicle type, pericarp colour, presence or absence of awn, seed type and degree of grain shattering. The NBWR accessions exhibited a combination of morphological traits from open panicle, grain with awns, red pericarp, short grain type, and degrees of grain shattering. Others mimic commercial rices with close panicle, awnless grains, white pericarp, long or short grain-type. Invariably, the NBWRs mimic and stand as tall as cultivated rice namely MR219, MR220, or MR235 and these NBWR accessions stand among equals morphologically vis-a-vis the commercial rice varieties. Most accessions displayed varying degrees of grain shattering in excess of 50%, except Acc9 and Acc12. The seasonal dynamics of on the prevalence of dominant NBWR accessions were also displaying significant differences among farm blocks. While Bagan Terap farm block, for example, did not record any measurable changes in the dominant NBWR accessions over seasons, the Sungai Leman farm block recorded measurable season-mediated changes in the dominant NBWR accessions. Sungai Leman started with NBWR Acc3, Acc4, Acc5, Acc7, Acc8, and Acc12 in season 1 of 2006/2007, but no measurable records of Acc3 and Acc5 were shown in season 2 of 2007. In season 3 of 2007/2008, only Acc8 and Acc12 prevailed in the farm block. In Sawah Sempadan farm block, season 3 of 2007/2008 showed much reduced prevalence of NBWRs leaving only Acc8 and Acc12. Most accessions registered clump or under-dispersed spatial distribution pattern based on quantitative indices: variance-to-mean ratio (VMR) and Lloyd's patchiness values. The dynamics on the extent of infestation and prevalence of dominant NBWR accessions registered both season- and farm-block mediated differences. Most accessions showed VMR >1 thus indicative of having a clump or clustered spatial distribution, as exemplified by Acc3, Acc4, Acc7, Acc8 and Acc12 in all farm blocks throughout three seasons. Some accessions have either random or uniform distribution in a few farm blocks. The Acc8 has the highest population counts based on important value index, followed by Acc12, and both were the most dominant accession while Sawah Sempadan was the worst farm block infested by NBWR compared to other farm blocks. These results were discussed in relation with the current agronomic and weed management practices, water availability and extension services in the granary.

Structure and Function of RGD Peptides Derived from Disintegrin Proteins

  • Kim, Jiun;Hong, Sung-Yu;Park, Hye-seo;Kim, Doo-Sik;Lee, Weontae
    • Molecules and Cells
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    • v.19 no.2
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    • pp.205-211
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    • 2005
  • The Arg-Gly-Asp (RGD) sequence serves as the primary recognition site in extracellular matrix proteins, and peptides containing this sequence can mimic the biological activities of matrix proteins. We have initiated structure-function studies of two RGD containing peptides, RGD-5(AGGDD) and cyclic RGD-6(CARGDDC). Assays have shown that cyclic RGD-peptides inhibit platelet aggregation more efficiently than linear ones. NMR data revealed that RGD-5 and RGD-6 have entirely different conformation. RGD-5 has a linear extended structure and RGD-6 has a stable loop conformation. In RGD-5 the guanidinium group of Arg2 and the carboxyl group of Asp4 lie in parallel, whereas the side-chains of Arg3 and Asp5 of RGD-6 are located in different planes, supporting the idea that the stability of the cyclic form derives from the packing of the side chain of the Arg and Asp residues. The structural features of these peptides could provide a basis for designing new drugs against diseases related to platelet aggregation and as cancer antagonists.

Bisphenol-A as Endocrine Disruptor Released from Lacquer Coating in Food Cans

  • Beung Ho, Ryu
    • Journal of Life Science
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    • v.9 no.2
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    • pp.19-23
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    • 1999
  • Bisphenol-A and related conpounds recently have been reported to be estrogenic since it has been demonstrared in laboratory stuides that they mimic the effects of estrogen. Bisphenol-A refered to as "environmental estrogen" are suspected of causing health effect in living body through disruption of endocdrine system. In this review, the occurrence, environmental fate, and biological effects of bisphenol-A are presented. To provide understanding to the potential for endocrine disruption due to environmental estrogen, the physiology of bisphenol-A mammalian and fish is also reviewed. For empty can, the migrationof bisphenol-A form food conducted epoxy coating was effected by the test conditions and it increased in order to water and 4% acetic acid. Extracts from foods packed in lacquer coated can also showed estrogenic activity. Bisphenol-A was found as a contaminant not only in the liquid food cans, but also in water autoclave in can. The used of coating certain food-packaging material may require closer scrutiny to determine when bisphenol-A contribute to advert exposure of consumers to estrogenic xenobiotics. Human breast cancer MCF cell added bisphenol-A cultivated to study the ability of bisphenol-A to elicit of bisphenol-A estrogenic bioresponse in this system. Bisphenol-A, similar to estradiol, induced PR activation in transiently transfected anterior and posterior pituitary cells.

Effect of HRE and Bcl-2 on the Production of Plasminogen Activator in CHO cells

  • Bae, Geun-Won;No, Jeong-Gwon;Lee, Gyu-Min;Kim, Ik-Yeong;Kim, Ik-Hwan
    • 한국생물공학회:학술대회논문집
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    • 2002.04a
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    • pp.261-264
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    • 2002
  • CHO (Chinese hamster ovary) cells were transfected with plasmids containing both cis-acting HRE (hypoxia response element) and CMV-promoter that controls tissue-type plasminogen activator (t-PA). CHO cells with HRE produced 16.2 fold higher t-PA concentration than CHO cells without HRE. It was noted that hypoxia strongly induced CHO cell apoptosis. which resulted in decrease of cell viability and protein production. In this study. by introducing Bcl-2, anti-apoptotic gene, we tried to recover cell viability and increase the protein production. When batch culture of both control cells without transfection of Bcl-2 and cells transfected with Bcl-2 were performed in the absence of CoCl ι hypoxia mimic condition. the cells with Bcl-2 were effected specific cell growth rates, maximum cell density. Immunoblotting assay showed Bcl-2 was recombinant with HRE dependent t- P A expression cassette, and their expression level was depended on hypoxia. By introducing Bcl-2, both cell viability and maximum cell density could be increased.

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Noise Reduction in Single Fiber Auditory Neural Responses Based on Pattern Matching Algorithm

  • Woo, Ji-Hwan;Miller Charles A.;Abbas Paul J.;Hong, Sung-Hwa;Kim, In-Young;Kim, Sun-I.
    • Journal of Biomedical Engineering Research
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    • v.26 no.4
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    • pp.199-205
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    • 2005
  • When recording single-unit responses from neural systems, a common problem is the accurate detection of spikes (action potentials) in the presence of competing unwanted (noise) signals. While some sources of noise can be readily dealt with through filtering or 'template subtraction' techniques, other sources present a more difficult problem. In particular, noise components introduced by power supplies, which contain harmonics of the power-line frequency, can be particularly troublesome in that they can mimic the shape of the desired spikes. Thus, standard 'template subtraction' techniques or notch-filtering approaches are not appropriate. In this study, we propose the use of a novel template-subtraction scheme that involves estimating the power-line noise waveform and using cross-correlation techniques to subtract them from the recordings. This technique requires two key steps: (1) cross-correlation analysis of each recorded waveform extracts a robust representation of the power-line noise waveform and (2) a second level of cross-correlation to successfully subtract that representation from each recorded waveform. This paper describes this algorithm and provides examples of its implementation using actual recorded waveforms that are contaminated with these noise signals. An improvement (reduction) in the noise level is reported, as are suggestions for future implementation of this strategy.