• Title/Summary/Keyword: biological factors

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Correlation Analysis between Phenology of Salix spp. and Meteorological Factors (버드나무류 (Salix spp.)의 계절학적 특성과 주요 기상요인 상관분석)

  • Kim, Seong-Bo;Kim, Ji Yoon;Im, Ran-Young;Do, Yuno;Park, Hee-Sun;Joo, Gea-Jae;Kim, Gu-Yeon
    • Journal of Environmental Science International
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    • v.22 no.12
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    • pp.1633-1641
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    • 2013
  • The objective of this study was to analyze correlation between phenological characteristics of Salix spp. and meteorological factors in the Upo wetlands. Phenology of Salix subfragilis Andersson and Salix chaenomeloides Kimura was monitored from 2007 to 2012. Meteorological variables were monitored by Korea Meteorological Administration (Hap-chon). Average date of flowering, fruiting, seed dispersion was 86, 113, 136 days for S. subfragilis and 112, 140, 164 days for S. chaenomeloides as Julian days. Flowering of S. subfragilis and S. chaenomeloides were correlated with daily mean air temp. in March (r=-0.92, r=-0.85, p<0.05). Fruiting of S. subfragilis was correlated with total precipitation between Jan and March of previous year (r=-0.90, p<0.01), however, the fruiting of S. chaenomeloides was highly correlated with max. temp. in Jan of previous year (r=0.99, p<0.01). Seed dispersion of both species is correlated with min. temp. in Feb. Phenology monitoring will contribute to understanding Salix spp. response against climate change.

Maternal-Conceptus Interactions: Mediators Regulating the Implantation Process in Pigs

  • Choi, Yohan;Seo, Heewon;Yoo, Inkyu;Han, Jisoo;Jang, Hwanhee;Kim, Minjeong;Ka, Hakhyun
    • Reproductive and Developmental Biology
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    • v.38 no.1
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    • pp.9-19
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    • 2014
  • For successful embryo implantation, the communication of the maternal endometrium with the conceptus trophectoderm is required essentially. In pigs, conceptuses undergo morphological change in length to enlarge the physical contact area with the maternal endometrium and secrete estrogen to induce the maternal recognition of pregnancy during the peri-implantation period. Conceptus-derived estrogen prevents luteolysis by conversion in direction of $PGF_{2{\alpha}}$ secretion from the uterine vasculature to the uterine lumen as well as it affects on expression of the uterine endometrial genes. In addition to estrogen, conceptuses release various signaling molecules, including cytokines, growth factors, and proteases, and, in response to these signaling molecules, the maternal uterine endometrium also synthesizes many signaling molecules, including hormones, cytokines, growth factors, lipid molecules, and utilizes ions such as calcium ion by calcium regulatory molecules. These reciprocal interactions of the conceptus trophectoderm with the maternal uterine endometrium make development and successful implantation of embryos possible. Thus, signaling molecules at the maternal-conceptus interface may play an important role in the implantation process. This review summarized syntheses and functions of signaling molecules at the maternal-conceptus interface to further understand mechanisms of the embryo implantation process in pigs.

Characteristics and distribution of terpenes in South Korean forests

  • Lee, Jaeseok;Cho, Kyoung Sang;Jeon, Youngjae;Kim, Ji Beom;Lim, Young-ran;Lee, Kyungho;Lee, Im-Soon
    • Journal of Ecology and Environment
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    • v.41 no.5
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    • pp.132-141
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    • 2017
  • The importance of forests continues to increase throughout the world, and one of the reasons is that a forest is a major place to emit terpenes, which have been reported to be beneficial to human health. In South Korea, forests occupy about 64% of the total land area and consist mainly of pine and oak trees. Since only a limited number of forests have been analyzed to date, a comprehensive understanding of terpenes emitted from regional forests remains in its infancy in Korea. Here, to gain insights into terpenes from regional forests located in South Korea, we review the characteristics of Korean forests and recent studies on major terpenes emitted from regional forests as well as from native trees dominant in South Korea. We also discuss meteorological factors that affect the terpene emissions in Korean forests. In conclusion, 18 types of terpenes were detected in Korean forests and their compositions in different forests are largely dependent on the dominant plant species in the forest. Moreover, terpene emissions in Korean forests are affected by various environmental factors, including temperature, amount and duration of daylight, season, and age of trees. To improve the understanding of the characteristics of terpene distribution, more studies are required on the terpene production of Korean forests in various regions.

A genome-wide approach to the systematic and comprehensive analysis of LIM gene family in sorghum (Sorghum bicolor L.)

  • Md. Abdur Rauf Sarkar;Salim Sarkar;Md Shohel Ul Islam;Fatema Tuz Zohra;Shaikh Mizanur Rahman
    • Genomics & Informatics
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    • v.21 no.3
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    • pp.36.1-36.19
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    • 2023
  • The LIM domain-containing proteins are dominantly found in plants and play a significant role in various biological processes such as gene transcription as well as actin cytoskeletal organization. Nevertheless, genome-wide identification as well as functional analysis of the LIM gene family have not yet been reported in the economically important plant sorghum (Sorghum bicolor L.). Therefore, we conducted an in silico identification and characterization of LIM genes in S. bicolor genome using integrated bioinformatics approaches. Based on phylogenetic tree analysis and conserved domain, we identified five LIM genes in S. bicolor (SbLIM) genome corresponding to Arabidopsis LIM (AtLIM) genes. The conserved domain, motif as well as gene structure analyses of the SbLIM gene family showed the similarity within the SbLIM and AtLIM members. The gene ontology (GO) enrichment study revealed that the candidate LIM genes are directly involved in cytoskeletal organization and various other important biological as well as molecular pathways. Some important families of regulating transcription factors such as ERF, MYB, WRKY, NAC, bZIP, C2H2, Dof, and G2-like were detected by analyzing their interaction network with identified SbLIM genes. The cis-acting regulatory elements related to predicted SbLIM genes were identified as responsive to light, hormones, stress, and other functions. The present study will provide valuable useful information about LIM genes in sorghum which would pave the way for the future study of functional pathways of candidate SbLIM genes as well as their regulatory factors in wet-lab experiments.

Development of the Structural Model of Adolescent's Risk Behavior (청소년의 위험행동 구조모형 구축)

  • Park, Hyun-Sook;Jung, Sun-Young
    • Journal of Korean Academy of Nursing
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    • v.41 no.3
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    • pp.364-373
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    • 2011
  • Purpose: In this study the fitness of a path model for the relationship among biological risk disposition, sociocultural risk factors, self-control, parent-adolescent communication, and risk behavior in adolescents was examined. Methods: The participants were 387 adolescents. The data were analyzed with the PASW 18.0 and AMOS 18.0 programs. Results: Sociocultural risk factors, self-control, and parent-adolescent communication showed a direct effect on risk behavior for adolescents, while biological risk disposition and sociocultural risk factor showed an indirect effect on risk behavior for adolescents. The modified path model of adolescents' risk behavior was showed a good fit with the model ($X^2$/df=2.37, GFI=.95, AGFI=.92, RMSEA=.06 [.05

Application of TMAH-based Pyrolysis Mass Spectrometry to a Biological Detection System (TMAH에 기반한 열분해 질량분석법의 생물 탐지체계 적용)

  • Kim, Ju-Hyun
    • Journal of the Korea Institute of Military Science and Technology
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    • v.14 no.2
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    • pp.289-298
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    • 2011
  • TMAH-based Py-MS has been investigated to apply for a real-time classification of biological agents in the field. Acquiring reproducible data from mass spectrometry is a key to biological detection in the field. Nevertheless, it has been little studied on what factors could affect to the reproducibility of the TMAH-based Py-MS spectrum patterns. Given the TMAH-based Py-MS applied to the field system, several factors which could affect to the reproducible pattern of TMAH-based Py-MS spectra are needed to be examined, including changes in TMAH injection volume, growth temperature for microorganism, and number of cells collected in pyrolyzer, and implication of stabilizer used for lyophilization. This study showed that the reproducibility of the spectrum patterns was significantly hindered by changes in TMAH concentration and cell number, and stabilizer implication but not by growth temperature. Among those at low TMAH concentration(0.015m) was not observed the significant alterations of the spectrum pattern even when its injection volume was changed, yet was in different cell numbers and stabilizer implication.

Systemic Statistical Optimization of Astaxanthin Inducing Methods in Haematococcus pluvialis cells -Statistical Optimization of Astaxanthin Production in Haematococcus

  • Kim, Sun-Hyoung;Jeong, Sung Eun;Hong, Seong-Joo;Lee, Choul-Gyun
    • Journal of Marine Bioscience and Biotechnology
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    • v.6 no.1
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    • pp.31-40
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    • 2014
  • The production of astaxanthin in the microalga Haematococcus pluvialis has been investigated using a sequential methodology based on the application of two types of statistical designs. The employed preliminary experiment was a fractional factorial design $2^6$ in which the factors studied were: excessive irradiance and nitrate starvation, phosphate deficiency, acetate supplementation, salt stress, and elevated temperature. The experimental results indicate that the amount of astaxanthin accumulation in the cells can be enhanced by excessive irradiance and nitrate starvation whereas the other factors tested did not yield any enhancement. In the subsequent experiment, a central composite design was applied with four variables, light intensity, nitrate, phosphate, and acetate, at five levels each. The optimal conditions for the highest astaxanthin production were found to be $1040{\mu}E/(m^2{\cdot}s)$ light intensity, 0.04 g/L nitrate, 0.31 g/L phosphate, 0.05 g/L acetate concentration.

Research Trends in Quantitative Nursing Studies and Quality Assessment of Intervention Studies in Patients with Heart Failure in South Korea (심부전 환자 대상 국내 양적 간호연구 분석 및 중재연구의 질 평가)

  • Son, Youn-Jung;Seo, Eun Ji
    • Journal of Korean Biological Nursing Science
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    • v.19 no.4
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    • pp.227-240
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    • 2017
  • Purpose: The purpose of this review was to identify the current status of nursing studies on heart failure (HF) patients in South Korea and to suggest future study direction. Methods: A literature review of databases such as KoreaMed, KERIS and nursing and allied health journal were searched with key terms 'heart failure' and 'nursing' for the period from January 2000 to February 2017. A total of 35 studies including 28 articles and 7 theses met the inclusion criteria. Results: Twenty-seven out of 35 studies were observational studies on outpatients and most of the studies did not mention the ejection fraction and New York Heart Association functional classification class (NYHA class) in the inclusion criteria. Self-care and health-related quality of life as psychological factors, and physical activity as a biological factor, were used as main variables. However, we found it difficult to understand how much score indicates better quality of life because of an inconsistent and wide score. In quality assessment, 8 intervention studies had no serious flaws. Conclusion: Further studies should consider more biological and social factors influencing HF. The quality assessment with respect to nursing intervention studies in HF showed that randomized and double-blind trials are needed.

The trinity of ribosome-associated quality control and stress signaling for proteostasis and neuronal physiology

  • Park, Jumin;Park, Jongmin;Lee, Jongbin;Lim, Chunghun
    • BMB Reports
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    • v.54 no.9
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    • pp.439-450
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    • 2021
  • Translating ribosomes accompany co-translational regulation of nascent polypeptide chains, including subcellular targeting, protein folding, and covalent modifications. Ribosome-associated quality control (RQC) is a co-translational surveillance mechanism triggered by ribosomal collisions, an indication of atypical translation. The ribosome-associated E3 ligase ZNF598 ubiquitinates small subunit proteins at the stalled ribosomes. A series of RQC factors are then recruited to dissociate and triage aberrant translation intermediates. Regulatory ribosomal stalling may occur on endogenous transcripts for quality gene expression, whereas ribosomal collisions are more globally induced by ribotoxic stressors such as translation inhibitors, ribotoxins, and UV radiation. The latter are sensed by ribosome-associated kinases GCN2 and ZAKα, activating integrated stress response (ISR) and ribotoxic stress response (RSR), respectively. Hierarchical crosstalks among RQC, ISR, and RSR pathways are readily detectable since the collided ribosome is their common substrate for activation. Given the strong implications of RQC factors in neuronal physiology and neurological disorders, the interplay between RQC and ribosome-associated stress signaling may sustain proteostasis, adaptively determine cell fate, and contribute to neural pathogenesis. The elucidation of underlying molecular principles in relevant human diseases should thus provide unexplored therapeutic opportunities.

Early-life exposure to endocrine disrupting chemicals associates with childhood obesity

  • Yang, Chunxue;Lee, Hin Kiu;Kong, Alice Pik Shan;Lim, Lee Ling;Cai, Zongwei;Chung, Arthur C.K.
    • Annals of Pediatric Endocrinology and Metabolism
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    • v.23 no.4
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    • pp.182-195
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    • 2018
  • Increasing prevalence of childhood obesity poses threats to the global health burden. Because this rising prevalence cannot be fully explained by traditional risk factors such as unhealthy diet and physical inactivity, early-life exposure to endocrine disrupting chemicals (EDCs) is recognized as emerging novel risk factors for childhood obesity. EDCs can disrupt the hormone-mediated metabolic pathways, affect children's growth and mediate the development of childhood obesity. Many organic pollutants are recently classified to be EDCs. In this review, we summarized the epidemiological and laboratory evidence related to EDCs and childhood obesity, and discussed the possible mechanisms underpinning childhood obesity and early-life exposure to non-persistent organic pollutants (phthalates, bisphenol A, triclosan) and persistent organic pollutants (dichlorodip henyltrichloroethane, polychlorinated biphenyls, polybrominated diphenyl ethers, per- and polyfluoroalkyl substances). Understanding the relationship between EDCs and childhood obesity helps to raise public awareness and formulate public health policy to protect the youth from exposure to the harmful effects of EDCs.