• The Korean Journal of Pain
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• v.9 no.2
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• pp.336-339
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• 1996

Stellate ganglion block which usually practiced in pain clinics may combined with hemodynamic changes because it blocks sympathetic nerve chains. We measured the hemodynamic changes with NCCOM3-$R7^{(R)}$ (BOMED, U.S.A.) which applicated bioimpedance method in twenty-two patients. Mean arterial pressure, heart rate, cardiac output, ejection fraction and left ventricle end diastolic volume (LEDV) were measured before stellate ganglion block (control), 1, 3, 5, 10 and 20 minutes after stellate ganglion block with 8 ml of 0.25% bupivacaine. The results were as follows: Mean arterial pressure decreased significantly (p<0.05) in 10, 20 minutes after stellate ganglion block comparing to control, but not clinically significant. Heart rate, cardiac output, ejection fraction and LVEDV showed no significant change compared to control value. These results showed that stellate ganglion block is a safe technique without significant hemodynamic changes.

• Proceedings of the KIEE Conference
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• 2005.10b
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• pp.75-77
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• 2005

When measuring impedance of electronic component and so on, even the small size can reject the interference to shielding object. But, the interference through human body is grown when measuring bioimpedance without establishing shield specially. Consequently, when measuring bioimpedance in this paper, it proposed impedance measurement method to take advantage of spread spectrum technology, so that can reject the interference without establishing shield specially. Spread spectrum impedance measurement method to propose in this paper can reject the interference signal that occurring from medical instruments in the human body, the interference signal that is flowed in from surrounding environment when measuring impedance. It improved SJR(signal to jamming ratio) about 22dB than conventional method that actually realize and experiment spread spectrum impedance measurement method.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.65 no.1
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• pp.194-199
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• 2016

EMG has specific information which is related to movements according to the activities of muscles. Therefore, users can intuitively control a prosthesis. For this reason, biosignals are very useful and convenient in this kind of application. Bioimpednace also provides specific information about movements like EMG. In this study, we used both EMG and bioimpedance to classify the typical hand gestures such as hand open, hand close, no motion (rest), supination, and pronation. Nine able-bodied subjects and one amputee were used as experimental data set. The accuracy was $98{\pm}1.9%$ when 2 bio-impedance and 8 EMG channels were used together for normal subjects. The number of EMG channels affected the accuracy, but it was stable when more than 5 channels were used. For the amputee, the accuracy is higher when we use both of them than when using only EMG. Therefore, accurate and stable hand motion estimation is possible by adding bioimepedance which shows structural information and EMG together.

• Journal of Physiology & Pathology in Korean Medicine
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• v.36 no.3
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• pp.94-99
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• 2022

The discovery of biomarkers related to pattern identification (PI), the core diagnostic theory of Korean medicine (KM), is one of the methods that can provide objective and reliable evidence by applying PI to clinical practice. In this study, 40 diabetic patients and 41 healthy control subjects recruited from the Korean medicine clinic were examined to determine the human electrical response related to the deficiency pattern, a representative pattern of diabetes. Qi-Blood-Yin-Yang deficiency pattern scores, which are representative deficiency patterns for diabetes mellitus, were obtained through a questionnaire with verified reliability and validity, and the human electrical response was measured non-invasively using a bioimpedance meter. In ANCOVA analysis using gender as a covariate, the 5 kHz frequency resistance and 5-250 kHz frequency reactance were significantly lower in the diabetic group than in non-diabetic control group. In addition, the multiple regression analysis showed a positive correlation (R2=0.11~0.19) between the Yang deficiency pattern score and resistance value for the diabetic group; the correlation was higher at higher frequencies of 50kHz (R2=0.18) and 250kHz (R2=0.19) compared to 5kHz(R2=0.11). In contrast, there was no such significant association in the control group. It implies that bioimpedance resistance measured at finite frequencies may be useful in predicting Yang deficiency, which is closely related to diabetic complications by reflecting the decrease in body water content and metabolism. In the future, large-scale planned clinical studies will be needed to identify biomarkers associated with different types of PI in diabetes.

• Journal of Sensor Science and Technology
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• v.20 no.2
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• pp.71-76
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• 2011

To characterize the relationship between the stage of hepatic fibrosis and bioimpedance, several electric parameters were estimated in rats with $CCl_4$-induced liver fibrosis. Thirty three Sprague-Dawley rats were intraperitoneally injected with a $CCl_4$-mineral oil mixture (1:1, 0.2 mL/100 g) twice a week for 8 weeks. The resistance(R), reactance(X), impedance(Z), and dissipation factor(D) between 1 kHz and 100 kHz were then evaluated in the livers of the rats under pentobarbital anesthesia using an HP4294A Impedance Analyzer. The rats were killed 2, 4, 6, and 8 weeks later, and their livers were classified in accordance with Ishak's scoring system. R, X, and Z changed in accordance with the progression of hepatic fibrosis and the changes were greater at lower frequencies than at higher frequencies. In comparison, the D spectrum was biphasic; D increased initially then decreased with increasing frequency. All of the parameters(R, X, Z, and D) changed in accordance with the stage of fibrosis in the livers, but D changed specifically with the progression of fibrosis. These results indicate that hepatic fibrosis may be evaluated by determining the changes in D.

• Proceedings of the IEEK Conference
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• 2003.07c
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• pp.2753-2756
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• 2003

A convenient, tunable loop-gain negative impedance circuit that increases input impedance of a front-end in a bioimpedance measurement has been proposed. Since the proposed circuit comprises wide-band operational amplifiers, selecting operational amplifiers is easy, while an operational amplifier of proper bandwidth should be chosen to use conventional circuit. Also, since loop-gain can be controlled by a feedback resistor connected serially with a feedback capacitor, loop-gain is tunable with a potentiometer. The input impedance of the proposed circuit is two times larger than that of the conventional circuit. Furthermore, closed loop phase response of the proposed circuit is better than that of the conventional circuit or without a negative capacitance circuit. The implemeted, proposed circuit showed stable operation and a zero input capacitance.

• The Transactions of the Korean Institute of Electrical Engineers D
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• v.55 no.4
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• pp.195-197
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• 2006

When we measure electrical impedance of a small object, such as an electronic component, external interference or jamming signal can be rejected by shielding the object. However, when we measure impedance of a large object, such as a human body, shielding is not easy and severe error due to the external interference could be introduced. In this paper, spread spectrum technique applicable to bioimpedance measurements for rejecting external interference without shielding is introduced. The improvement in signal-to-jamming ratio by the spread spectrum technique was experimentally confirmed.

• Proceedings of the KIEE Conference
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• 2003.11b
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• pp.179-182
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• 2003

A simulation on bootstrapping circuit has been performed by modelling a coaxial cable as a transmission line. It is shown that the bootstrapping circuit could be unstable due to the transmission line effect though an ideal amplifier is used. While the conventional bootstrapping circuit does not cancel the input capacitance of the input buffer, a new bootstrapping circuit that cancels input capacitance of the input buffer has been proposed. The proposed bootstrapping circuit consists of the input buffer of which gam is larger than 1 and a feedback resistor to control the loop gain. The proposed bootstrapping circuit has higher input impedance than that of the conventional circuit.

• Proceedings of the KIEE Conference
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• 2003.11c
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• pp.940-942
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• 2003

This paper describes the possibility of analyzing gait pattern from the variation of the lower leg electrical impedance. This impedance is measured by the four-electrode method. Two current electrodes are applied to the thigh and foot, and two potential electrodes are applied to the lateral aspect, medial aspect, and posterior position of lower leg. We found the optimal electrode position for knee and ankle joint movements based on high correlation coefficient, least interference, and maximum magnitude of impedance change. From such features of the lower leg impedance, it has been made clear that different movement patterns exhibit different impedance patterns and impedance level.

• Journal of Biomedical Engineering Research
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• v.22 no.6
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• pp.503-510
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• 2001

In this paper. we describe a 32-channel bioimpedance measurement system It consists of 32 independent constant current sources of 50 kHz sinusoid. The amplitude of each current source can be adjusted using a 12-bit MDAC. After we applied a pattern of injection currents through 32 current injection electrodes. we measured induced boundary voltages using a variable-gain narrow-band instrumentation amplifier. a Phase-sensitive demodulator. and a 12-bit ADC. The system is interfaced to a PC for the control and data acquisition. We used the system to detect anomalies with different resistivity values in a saline Phantom with 290mm diameter The accuracy of the developed system was estimated as 2.42% and we found that anomalies larger than 8mm in diameter can be detected. We Plan to improve the accuracy by using a digital oscillator improved current sources by feedback control, Phase-sensitive A/D conversion. etc. to detect anomalies smaller than 1mm in diameter.