• Title/Summary/Keyword: bio-inspired

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An research of the error detection method and efficient recovery algorithms in the DNA double helix (DNA 이중나선에서의 오류위치 검출 방법 및 효율적인 복구 알고리즘 연구)

  • Kim, SokeHwan;Hur, Chang-Wu
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.16 no.11
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    • pp.2557-2562
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    • 2012
  • In order to maintain order in the genetic information at cells, it need ongoing monitoring and recovery system. DNA is accomplished by a combination of base pairs, Wrong base pairs is formed with a much more lower frequency than the normal DNA. if it does not modify and was accumulate, the Cells were died. In this study, mistakes of DNA replication and repair of the damaged part was introduced engineering concepts by mimicking DNA repair functions. It was presented recover the complementary part of the previously announced and presented an efficient algorithm at find and recover the complementary part.

Applying Particle Swarm Optimization for Enhanced Clustering of DNA Chip Data (DNA Chip 데이터의 군집화 성능 향상을 위한 Particle Swarm Optimization 알고리즘의 적용기법)

  • Lee, Min-Soo
    • The KIPS Transactions:PartD
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    • v.17D no.3
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    • pp.175-184
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    • 2010
  • Experiments and research on genes have become very convenient by using DNA chips, which provide large amounts of data from various experiments. The data provided by the DNA chips could be represented as a two dimensional matrix, in which one axis represents genes and the other represents samples. By performing an efficient and good quality clustering on such data, the classification work which follows could be more efficient and accurate. In this paper, we use a bio-inspired algorithm called the Particle Swarm Optimization algorithm to propose an efficient clustering mechanism for large amounts of DNA chip data, and show through experimental results that the clustering technique using the PSO algorithm provides a faster yet good quality result compared with other existing clustering solutions.

Study of composite structure design and manufacturing for compliant legged robot (유연다리로봇 복합구조 설계 및 제작 기술 연구)

  • Choi, Rock-Hyun;Kang, Yoo-Na;Aulia, Widya;Lee, Gyoung-Jae;Lee, Dong-Ha;Kwon, Oh-Seok;Moon, Sang-Jun
    • 한국태양에너지학회:학술대회논문집
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    • 2012.03a
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    • pp.410-413
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    • 2012
  • A traditional fabrication method is very difficult to make small robots using embedded sensors, actuators and connectors. Fortunately, Shape Deposition Manufacturing can provide an alternative method, and it has many benefits. Firstly, the weight of robot can be lighter, as it can be consisted of composite materials. Secondly, SDM can make simple robot structures because this approach does not need to use connectors and fasteners. Lastly, SDM gives stiffness and flexibility at the specific parts. Therefore, in this paper, we present a design of 3 segment legs organized by SDM, what the SDM approach is, and compare SDM method with 3 segment prototype legs which uses a traditional approach and made by DGIST.

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Vision chip for edge detection with resolution improvement through simplification of unit-pixel circuit (단위 픽셀 회로의 간소화를 통해서 해상도를 향상시킨 이차원 윤곽 검출용 시각칩)

  • Sung, Dong-Kyu;Kong, Jae-Sung;Hyun, Hyo-Young;Shin, Jang-Kyoo
    • Journal of Sensor Science and Technology
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    • v.17 no.1
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    • pp.15-22
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    • 2008
  • When designing image sensors including a CMOS vision chip for edge detection, resolution is a significant factor to evaluate the performance. It is hard to improve the resolution of a bio-inspired CMOS vision using a resistive network because the vision chip contains many circuits such as a resistive network and several signal processing circuits as well as photocircuits of general image sensors such as CMOS image sensor (CIS). Low resolution restricts the use of the application systems. In this paper, we improve the resolution through layout and circuit optimization. Furthermore, we have designed a printed circuit board using FPGA which controls the vision chip. The vision chip for edge detection has been designed and fabricated by using $0.35{\mu}m$ double-poly four-metal CMOS technology, and its output characteristics have been investigated.

In vivo ESR measurement of free radical reaction in living mice

  • Han, Jin-Yi;Hideo Utsumi
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 2000.04a
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    • pp.6-7
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    • 2000
  • Recently, free radicals such as active oxygen species, nitric oxide, etc are believed to be one of the key substances in physiological and pathological, toxicological phenomena, and oxidative damages, and all organism have defencing system against such as free radicals. Formation and extinction of free radicals may be regulated through bio-redox system, in which various enzymes and compounds should be involved in very complicated manner. Thus, direct and non-invasive measurement of in vivo free radical reactions with living animals must be essential to understand the role of free radicals in pathophysiological phenomena. Electron spin resonance spectroscopy (ESR) is very selective and sensitive technique to detect free radicals, but a conventional ESR spectrometer has large detect in application to living animals, since high frequent microwave is absorbed with water, resulting in generation of high fever in living body. In order to estimate in vivo free radical reactions in living whole animals, we develop in vivo ESR-CT technique using nitroxide radicals as spin probes. Nitroxide radicals and their reduced forms, hydroxylamines, are known to interact with various redox systems. We found that! ! the signal decay due to reduction of nitroxyl radicals is influenced by aging, inspired oxygen concentration, ischemia-referfusion injury, radiation, etc. In the present paper, I will introduce in vivo ESR technique and my laboratory recent results concerning non-invasive evaluation of free radical reactions in living mice.

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Highly Sensitive Tactile Sensor Using Single Layer Graphene

  • Jung, Hyojin;Kim, Youngjun;Jin, Hyungki;Chun, Sungwoo;Park, Wanjun
    • Proceedings of the Korean Vacuum Society Conference
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    • 2014.02a
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    • pp.229.1-229.1
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    • 2014
  • Tactile sensors have widely been researched in the areas of electronics, robotic system and medical tools for extending to the form of bio inspired devices that generate feeling of touch mimicking those of humans. Recent efforts in adapting the tactile sensor have included the use of novel materials with both scalability and high sensitivity [1]. Graphene, a 2-D allotrope of carbon, is a prospective candidate for sensor technology, having strong mechanical properties [2] and flexibility, including recovery from mechanical stress. In addition, its truly 2-D nature allows the formation of continuous films that are intrinsically useful for realizing sensing functions. However, very few investigations have been carrier out to investigate sensing characteristics as a device form with the graphene subjected to strain/stress and pressure effects. In this study, we present a sensor of vertical forces based on single-layer graphene, with a working range that corresponds to the pressure of a gentle touch that can be perceived by humans. In spite of the low gauge factor that arises from the intrinsic electromechanical character of single-layer graphene, we achieve a resistance variation of about 30% in response to an applied vertical pressure of 5 kPa by introducing a pressure-amplifying structure in the sensor. In addition, we demonstrate a method to enhance the sensitivity of the sensor by applying resistive single-layer graphene.

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An research of the error detection method and efficient recovery algorithms in the DNA double helix. (DNA 이중나선에서의 오류위치 검출 방법 및 효율적인 복구 알고리즘 연구)

  • Kim, Soke-Hwan;Hur, Chang-Wu
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2012.10a
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    • pp.293-297
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    • 2012
  • In order to maintain order in the genetic information at cells, it need ongoing monitoring and recovery system. DNA is accomplished by a combination of base pairs, Wrong base pairs is formed with a much more lower frequency than the normal DNA. if it does not modify and was accumulate, the Cells were died. In this study, mistakes of DNA replication and repair of the damaged part was introduced engineering concepts by mimicking DNA repair functions. It was presented recover the complementary part of the previously announced and presented an efficient algorithm at find and recover the complementary part.

  • PDF

Bio-inspired Cell Deformability Monitoring Chips Based on Strain Dependent Digital Lysis Rates (미소유로의 길이에 따른 통과세포의 파괴율을 바탕으로 한 생체모사 세포 변형성 검사칩에 관한 연구)

  • Youn, Se-Chan;Lee, Dong-Woo;Cho, Young-Ho
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.32 no.10
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    • pp.844-849
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    • 2008
  • We present a novel cell deformability monitoring chip based on the digitally measured cell lysis rate which is dependent on the areal strain of the cell membrane. This method offers simple cell deformability monitoring by automated high-throughput testing system. We suggest the filter design considering the areal strain imposed on the cell membrane passing through the filter array having gradually increased orifice length. In the experiment using erythrocytes, we characterized the cell deformability in terms of average fracture areal strain which was $0.24{\pm}0.014\;and\;0.21{\pm}0.002$ for normal and chemically treated erythrocytes, respectively. We also verified that the areal strain of 0.15 effectively discriminates the deformability difference of normal and chemically treated erythrocytes, which can be applied to the clinical situation. We compared the lysis rates and their difference for the samples from different donors and found that the present chips can be commonly used without any calibration process. The experimental results demonstrate the simple structure and high performance of the present cell deformability monitoring chips, applicable to simple and cost-effective cell aging process monitoring.

Resource Allocation with Proportional Rate In Cognitive Wireless Network: An Immune Clonal Optimization Scheme

  • Chai, Zheng-Yi;Zhang, De-Xian;Zhu, Si-Feng
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.6 no.5
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    • pp.1286-1302
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    • 2012
  • In this paper, the resource allocation problem with proportional fairness rate in cognitive OFDM-based wireless network is studied. It aims to maximize the total system throughput subject to constraints that include total transmit power for secondary users, maximum tolerable interferences of primary users, bit error rate, and proportional fairness rate among secondary users. It is a nonlinear optimization problem, for which obtaining the optimal solution is known to be NP-hard. An efficient bio-inspired suboptimal algorithm called immune clonal optimization is proposed to solve the resource allocation problem in two steps. That is, subcarriers are firstly allocated to secondary users assuming equal power assignment and then the power allocation is performed with an improved immune clonal algorithm. Suitable immune operators such as matrix encoding and adaptive mutation are designed for resource allocation problem. Simulation results show that the proposed algorithm achieves near-optimal throughput and more satisfying proportional fairness rate among secondary users with lower computational complexity.

Attack-Proof Cooperative Spectrum Sensing Based on Consensus Algorithm in Cognitive Radio Networks

  • Liu, Quan;Gao, Jun;Guo, Yunwei;Liu, Siyang
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.4 no.6
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    • pp.1042-1062
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    • 2010
  • Cooperative spectrum sensing (CSS) is an effective technology for alleviating the unreliability of local spectrum sensing due to fading/shadowing effects. Unlike most existing solutions, this paper considers the use of CSS technology in decentralized networks where a fusion center is not available. In such a decentralized network, some attackers may sneak into the ranks of cooperative users. On the basis of recent advances in bio-inspired consensus algorithms, an attack-proof, decentralized CSS scheme is proposed in which all secondary users can maintain cooperative sensing by exchanging information locally instead of requiring centralized control or data fusion. Users no longer need any prior knowledge of the network. To counter three potential categories of spectrum sensing data falsification (SSDF) attacks, some anti-attack strategies are applied to the iterative process of information exchange. This enables most authentic users to exclude potentially malicious users from their neighborhood. As represented by simulation results, the proposed scheme can generally ensure that most authentic users reach a consensus within the given number of iterations, and it also demonstrates much better robustness against different SSDF attacks than several existing schemes.