• Title/Summary/Keyword: bio materials

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Synthesis of Aluminum Nitride Nanopowders by Carbothermal Reduction of Aluminum Oxide and Subsequent In-situ Nitridization (산화알루미늄 분말의 탄소열환원 및 직접 질화반응을 통한 질화알루미늄 나노분말의 합성)

  • Seo, Kyung-Won;Lee, Seong-Yong;Park, Jong-Ku;Kim, Sung-Hyun
    • Journal of Powder Materials
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    • v.13 no.6 s.59
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    • pp.432-438
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    • 2006
  • Aluminum nitride (AlN) nanopowders with low degree of agglomeration and uniform particle size were synthesized by carbothermal reduction of alumina and subsequent direct nitridization. Boehmite powder was homogeneously admixed with carbon black nanopowders by ball milling. The powder mixture was treated under ammonia atmosphere to synthesize AlN powder at lour temperature. The effect of process variables such as boehmite/carbon black powder ratio, reaction temperature and reaction time on the synthesis of AlN nanopowder was investigated.

Effect of Surfactant on Homogeneity of Partially Degummed Silk Fiber

  • Chung, Da Eun;Um, In Chul
    • International Journal of Industrial Entomology and Biomaterials
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    • v.28 no.1
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    • pp.19-24
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    • 2014
  • Silk has always been one of the most favored textile materials. Fully degummed silk fiber (i.e., silk fibers without sericin) shows better luster than raw silk fiber (with sericin); it is also softer. On the other hand, raw silk fiber feels cooler because of the presence of sericin, making it useful as a textile for the summer season. Recently, partially degummed silk has attracted researchers' attention because it provides better luster, feel, and dyeing properties. However, the partial degumming of silk is very difficult because it results in inhomogeneously degummed fiber. In the present study, silk yarns were degummed with surfactant aqueous solutions and the effects of each surfactant on the degumming ratio, crystallinity, and homogeneity of the degummed silk yarn were examined. The degumming ratio and crystallinity index of silk yarn varied depending on the type of surfactant. On the whole, anionic surfactants resulted in higher degumming ratios and better homogeneity than nonionic surfactants.

Technology Trend of Luminescent Nanomaterials (나노입자 기반 발광 소재 연구동향)

  • Jeong, Hyewon;Son, Jae Sung
    • Journal of Powder Materials
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    • v.25 no.2
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    • pp.170-177
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    • 2018
  • Colloidally synthesized luminescent nanocrystals (NCs) have attracted tremendous attention due to their unique nanoscale optical and electronic properties. The emission properties of these NCs can be precisely tuned by controlling their size, shape, and composition as well as by introducing appropriate dopant impurities. Nowadays, these NCs are actively utilized for various applications such as optoelectronic devices including light emitting diodes (LEDs), lasers, and solar cells, and bio-medical applications such as imaging agents and bio-sensors. In this review, we classify luminescent nanomaterials into quantum dots (QDs), upconversion nanoparticles (UCNPs), and perovskite NCs and present their intrinsic emission mechanism. Furthermore, the recently emerging issues of efficiency, toxicity, and durability in these materials are discussed for better understanding of industry demands. As well, the future outlook will be offered for researchers to guide the direction of future research.

The Effects of Electron Beam Exposure Time on Transmission Electron Microscopy Imaging of Negatively Stained Biological Samples

  • Kim, Kyumin;Chung, Jeong Min;Lee, Sangmin;Jung, Hyun Suk
    • Applied Microscopy
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    • v.45 no.3
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    • pp.150-154
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    • 2015
  • Negative staining electron microscopy facilitates the visualization of small bio-materials such as proteins; thus, many electron microscopists have used this conventional method to visualize the morphologies and structures of biological materials. To achieve sufficient contrast of the materials, a number of imaging parameters must be considered. Here, we examined the effects of one of the fundamental imaging parameters, electron beam exposure time, on electron densities generated using transmission electron microscopy. A single site of a negatively stained biological sample was illuminated with the electron beam for different times (1, 2, or 4 seconds) and sets of micrographs were collected. Computational image processing demonstrated that longer exposure times provide better electron densities at the molecular level. This report describes technical procedures for testing parameters that allow enhanced evaluations of the densities of electron microscopy images.

Evaluation of the Anti-oxidant Activity of Pueraria Extract Fermented by Lactobacillus rhamnosus BHN-LAB 76 (Lactobacillus rhamnosus BHN-LAB 76에 의한 Pueraria 발효 추출물의 항산화 활성 평가)

  • Kim, Byung-Hyuk;Jang, Jong-Ok;Lee, Jun-Hyeong;Park, Ye-Eun;Kim, Jung-Gyu;Yoon, Yeo-Cho;Jeong, Su Jin;Kwon, Gi-Seok;Lee, Jung-Bok
    • Journal of Life Science
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    • v.29 no.5
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    • pp.545-554
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    • 2019
  • The phytochemical compounds of Pueraria, a medicinally important leguminous plant, include various isoflavones that have weak estrogenic activity and a potential role in preventing chronic disease, cancer, osteoporosis, and postmenopausal syndrome. However, the major isoflavones are derivatives of puerarin and occur mainly as unabsorbable and biologically inactive glycosides. The bioavailability of the glucosides can be increased by hydrolysis of the sugar moiety using ${\beta}$-glucosidase. In this study, we investigated the antioxidant effects of a Pueraria extract after fermentation by Lactobacillus rhamnosus BHN-LAB 76. The L. rhamnosus BHN-LAB 76 strain was inoculated into Pueraria powder and fermented at $37^{\circ}C$ for 72 hr. The total polyphenol content of the Pueraria extract increased by about 134% and the total flavonoid content increased around 110% after fermentation with L. rhamnosus BHN-LAB 76 when compared to a non-fermented Pueraria extract. Superoxide dismutase-like activities, DPPH radical scavenging, and ABTS radical scavenging increased by approximately 213%, 190%, and 107%, respectively, in the fermented Pueraria extract compared to the non-fermented Pueraria extract. Fermentation of Pueraria extracts with L. rhamnosus BHN-LAB 76 is therefore possible and can effectively increase the antioxidant effects. These results can be applied to the development of improved foods and cosmetic materials.

Increased Anti-oxidative Activity and Whitening Effects of a Saposhnikovia Extract Following Bioconversion Fermentation using Lactobacillus plantarum BHN-LAB 33 (Lactobacillus plantarum BHN-LAB 33의 생물전환공정을 통한 방풍 발효 추출물의 항산화 활성 및 미백 활성 증대 효과)

  • Kim, Byung-Hyuk;Jang, Jong-Ok;Lee, Jun-Hyeong;Park, YeEun;Kim, Jung-Gyu;Yoon, Yeo-Cho;Jeong, Su Jin;Kwon, Gi-Seok;Lee, Jung-Bok
    • Journal of Life Science
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    • v.29 no.11
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    • pp.1208-1217
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    • 2019
  • Saposhnikovia has been used as a traditional medicinal herb in Asia because of the reported anti-inflammatory, anti-allergic rhinitis, pro-whitening, anti-atopy, anti-allergy, and anti-dermatopathy effects of the phytochemical compounds it contains. In this study, we investigated the antioxidant effects of a Saposhnikovia extract after fermentation by Lactobacillus plantarum BHN-LAB 33. Saposhnikovia powder was inoculated with L. plantarum BHN-LAB 33 and fermented at $37^{\circ}C$ for 72 hr. After fermentation, the total polyphenol content of the Saposhnikovia extract increased by about 14%, and the total flavonoid content increased by about 9%. The superoxide dismutase-like activities, DPPH radical scavenging, ABTS radical scavenging, reducing power activity, and tyrosinase inhibition activity also increased after fermentation by approximately 70%, 80%, 45%, 39%, and 44%, respectively. The results confirmed that fermentation of a Saposhnikovia extract by L. plantarum BHN-LAB 33 is an effective way to increase the antioxidant effects of the extract. The bioconversion process investigated in this study may have the potential to produce phytochemical-enriched natural antioxidant agents with high added value from Saposhnikovia matrices. These results can also be applied to the development of improved foods and cosmetic materials.

A radiographical study on the changes in height of grafting materials after sinus lift: a comparison between two types of xenogenic materials

  • Hieu, Pham-Duong;Chung, Jin-Hyung;Yim, Sung-Bin;Hong, Ki-Seok
    • Journal of Periodontal and Implant Science
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    • v.40 no.1
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    • pp.25-32
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    • 2010
  • Purpose: The performance of implant surgery in the posterior maxilla often poses a challenge due to insufficient available bone. Sinus floor elevation was developed to increase the needed vertical height to overcome this problem. However, grafting materials used for the sinus lift technique eventually show resorption. The present study radiographically compared and evaluated the changes in height of the grafting materials after carrying out maxillary sinus elevation with a window opening procedure. This study also evaluated the difference between two xenogenic bone materials when being used for the sinus lifting procedure. Methods: Twenty-one patients were recruited for this study and underwent a sinus lift procedure. All sites were treated with either bovine bone (Bio-$Oss^{(R)}$) with platelet-rich plasma (PRP) or bovine bone (OCS-$B^{(R)}$)/PRP. A total of 69 implants were placed equally 6-8 months after the sinus lift. All sites were clinically and radiographically evaluated right after the implant surgery, 7-12 months, 13-24 months, and 25-48 months after their prosthetic loading. Results: Changes of implant length/bone length with time showed a statistically significant decreasing tendency (P<0.05). There was no significant change in the Bio-$Oss^{(R)}$ group (P>0.05). In contrast, the OCS-$B^{(R)}$ group showed a significant decrease with time (P<0.05). However, no significant difference was observed between the two groups (P>0.05). Conclusions: The results showed that there was significant reduction in comparison with data right after placement, after 7 to 12 months, 13 to 24 months, and over 25 months; however, reduction rates between each period have shown to be without significance. No significant difference in height change was observed between the Bio-$Oss^{(R)}$ and the OCS-$B^{(R)}$ groups.

Intracellular Electrical Stimulation on PC-12 Cells through Vertical Nanowire Electrode

  • Kim, Hyungsuk;Kim, Ilsoo;Lee, Jaehyung;Lee, Hye-young;Lee, Eungjang;Jeong, Du-Won;Kim, Ju-Jin;Choi, Heon-Jin
    • Proceedings of the Korean Vacuum Society Conference
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    • 2014.02a
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    • pp.407-407
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    • 2014
  • Nanotechnology, especially vertically grown silicon nanowires, has gotten great attentions in biology due to characteristics of one dimensional nanostructure; controllable synthetic structure such as lengths, diameters, densities. Silicon nanowires are promising materials as nanoelectrodes due to their highly complementary metal-oxide-semiconductor (CMOS) - and bio-compatibility. Silicon nanowires are so intoxicated that are effective for bio molecular delivery and electrical stimulation. Vertical nanowires with integrated Au tips were fabricated for electrical intracellular interfacing with PC-12 cells. We have made synthesized two types of nanowire devices; one is multi-nanowires electrode for bio molecular sensing and electrical stimulation, and the other is single-nanowires electrode respectively. Here, we demonstrate that differentiation of Nerve Growth Factor (NGF) treated PC-12 cells can be promoted depending on different magnitudes of electrical stimulation and density of Si NWs. It was fabricated by both bottom-up and top-down approaches using low pressure chemical vapor deposition (LPCVD) with high vacuuming environment to electrically stimulate PC-12 cells. The effects of electrical stimulation with NGF on the morphological differentiation are observed by Scanning Electron Microscopy (SEM), and it induces neural outgrowth. Moreover, the cell cytosol can be dyed selectively depending on the degree of differentiation along with fluorescence microscopy measurement. Vertically grown silicon nanowires have further expected advantages in case of single nanowire fabrication, and will be able to expand its characteristics to diverse applications.

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Development of a Rice Seed Pelleting Machine for Direct Seeding in Rice Cultivation (직파용 벼 펠렛종자 제조장치 개발)

  • 박종수;유수남;최영수;유대성
    • Journal of Biosystems Engineering
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    • v.27 no.5
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    • pp.381-390
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    • 2002
  • Direct seeding of rice-seed pellets is expected to be an alternative for solving problems in current direct seeding cultivation of rice. but mass production of rice-seed pellets is prerequisite for practical application. Design. construction and performance evaluation of an experimental rice seed pelleting machine were carried out for mass production of rice-seed pellets. The pelleting machine intended to make a ball type rice-seed pellet, which have 3∼5 rice seeds and diameter of which is 12 mm. Pellet materials ; rice seeds, soil, and binder were mixed and kneaded by the mixer. The designed rice seed pelleting machine fed pellet materials by screw conveyor to forming rolls and made rice-seed pellets. Capacity, ratio of perfect rice-seed pellets, seed and pellet material loss were investigated as mixing ratio of soil to rice seed and feeding rate of pellet materials. The pelleting machine showed up to 37,000 pellets/h of pelleting rate, 61∼71% of weight ratio of perfect rice-seed pellets to pellet materials supplied, 17∼48% of seed loss ratio. Average weight and average diameter of the pellets were 1.66 g and 12.0 mm. respectively. More than 3 rice seeds were included in most pellets at 6 : 1 of mixing ratio of soil to rice seed. And compression strength of the pellets was in the range of 88-130 N. To improve performance of the pelleting machine, improvements of the forming rolls, feeding mechanism, and discharging mechanism for reducing loss of pellet materials and seeds damage are needed.