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Application and First Evaluation of the Operational RAMS Model for the Dispersion Forecast of Hazardous Chemicals - Validation of the Operational Wind Field Generation System in CARIS (유해화학물질 대기확산 예측을 위한 RAMS 기상모델의 적용 및 평가 - CARIS의 바람장 모델 검증)

  • Kim, C.H.;Na, J.G.;Park, C.J.;Park, J.H.;Im, C.S.;Yoon, E.;Kim, M.S.;Park, C.H.;Kim, Y.J.
    • Journal of Korean Society for Atmospheric Environment
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    • v.19 no.5
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    • pp.595-610
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    • 2003
  • The statistical indexes such as RMSE (Root Mean Square Error), Mean Bias error, and IOA (Index of agreement) are used to evaluate 3 Dimensional wind and temperature fields predicted by operational meteorological model RAMS (Regional Atmospheric Meteorological System) implemented in CARIS (Chemical Accident Response Information System) for the dispersion forecast of hazardous chemicals in case of the chemical accidents in Korea. The operational atmospheric model, RAMS in CARIS are designed to use GDAPS, GTS, and AWS meteorological data obtained from KMA (Korean Meteorological Administration) for the generation of 3-dimensional initial meteorological fields. The predicted meteorological variables such as wind speed, wind direction, temperature, and precipitation amount, during 19 ∼ 23, August 2002, are extracted at the nearest grid point to the meteorological monitoring sites, and validated against the observations located over the Korean peninsula. The results show that Mean bias and Root Mean Square Error are 0.9 (m/s), 1.85 (m/s) for wind speed at 10 m above the ground, respectively, and 1.45 ($^{\circ}C$), 2.82 ($^{\circ}C$) for surface temperature. Of particular interest is the distribution of forecasting error predicted by RAMS with respect to the altitude; relatively smaller error is found in the near-surface atmosphere for wind and temperature fields, while it grows larger as the altitude increases. Overall, some of the overpredictions in comparisons with the observations are detected for wind and temperature fields, whereas relatively small errors are found in the near-surface atmosphere. This discrepancies are partly attributed to the oversimplified spacing of soil, soil contents and initial temperature fields, suggesting some improvement could probably be gained if the sub-grid scale nature of moisture and temperature fields was taken into account. However, IOA values for the wind field (0.62) as well as temperature field (0.78) is greater than the 'good' value criteria (> 0.5) implied by other studies. The good value of IOA along with relatively small wind field error in the near surface atmosphere implies that, on the basis of current meteorological data for initial fields, RAMS has good potentials to be used as a operational meteorological model in predicting the urban or local scale 3-dimensional wind fields for the dispersion forecast in association with hazardous chemical releases in Korea.

A Systematic Review of Risk Factors for Brain Metastases and Value of Prophylactic Cranial Irradiation in Non-Small Cell Lung Cancer

  • Sun, Dian-Shui;Hu, Li-Kuan;Cai, Ying;Li, Xiao-Mei;Ye, Lan;Hou, Hua-Ying;Wang, Cui-Hong;Jiang, Yu-Hua
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.3
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    • pp.1233-1239
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    • 2014
  • Background: The incidence of brain metastases (BM) varies in patients with non-small cell lung cancer (NSCLC), calls into question the value of prophylactic cranial irradiation (PCI). It is possible that clinicopathologic characteristics are associated with the development of BM, but these have yet to be identified in detail. Thus, we conducted the present meta-analysis on risk factors for BM and the value of PCI in patients with NSCLC. Methods: Eligible data were extracted and the risk factors for BM and the value of PCI in patients with NSCLC were analyzed by calculating the pooled odds ratio (OR). Heterogeneity was detected using Q and I-squared statistics, and publication bias was tested by funnel plots and Egger's test. Results: Six randomized controlled trials with a focus on the value of PCI and 13 eligible studies with a focus on risk factors for BM were included. PCI significantly reduced the incidence of BM in patients with NSCLC (p=0.000, pooled OR=0.34, 95% confidence interval = 0.37-0.59). Compared with non-squamous cell carcinoma, squamous cell carcinoma was associated with a low incidence of BM in patients with NSCLC (p=0.000, pooled OR=0.47, 95% confidence interval =0.34-0.65). The funnel plot and Egger's test suggested that there was no publication bias in the current meta-analysis. Conclusions: This meta-analysis provides statistical evidence that compared with non-squamous cell carcinoma, squamous cell carcinoma can be used as a predictor for BM in patients with NSCLC, and PCI might reduce the incidence of BM in patients with NSCLC, but does not provide a survival benefit.

Study on the Spin Valve Giant Magnetoresistance With a New Mn-Ir-Pt Antife rromagnetic Material (Mn-Ir-Pt 새로운 반강자성체를 사용한 스핀밸브 거대자기저항에 관한 연구)

  • 서수정;윤성용;김장현;전동민;김윤식;이두현
    • Journal of the Korean Magnetics Society
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    • v.11 no.4
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    • pp.141-145
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    • 2001
  • The Mn$\_$80/Ir$\_$18.1/Pt$\_$1.9/ exchange bias layers (EBLs), which have a small amounts of Pt, exhibit a high value of H$\_$ex/. The Si/Ni-Fe/Mn$\_$80/Ir$\_$18.1/Pt$\_$1.9/ EBL shows the largest H$\_$ex/ of 187 Oe, which is equivalent to a exchange energy (J$\_$ex/) of 0.146 erg/cm$^2$. Mn$\_$80/Ir$\_$18.1/Pt$\_$1.9/ EBLS are estimated to have blocking temperature of about 250 $\^{C}$, which is higher than those of Mn-Ir EBLs and Mn-Ir-Pt EBLs with higher Pt contents. This result implies that a little addition of Pt element promotes thermal stability in the Mn-Ir-Pt EBLs. The chemical stability of Mn-Ir-Pt EBLs was characterized by potentiodynamic test, which was performed in 0.001 M NaCl solution. The current density of Mn-Ir-Pt films was gradually reduced with increasing Pt content. The present results indicate that the Mn-Ir-Pt with a small amount of Pt is suitable for an antiferromagnetic material for a reliable spin valve giant magnetoresistance device.

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A Study of Global Ocean Data Assimilation using VAF (VAF 변분법을 이용한 전구 해양자료 동화 연구)

  • Ahn, Joong-Bae;Yoon, Yong-Hoon;Cho, Eek-Hyun;Oh, He-Ram
    • The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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    • v.10 no.1
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    • pp.69-78
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    • 2005
  • ARCO and TAO data which supply three dimensional global ocean information are assimilated to the background field from a general circulation model, MOM3. Using a variational Analysis using Filter (VAF), which is a spatial variational filter designed to reduce computational time and space efficiently and economically, observed ARGO and TAO data are assimilated to the OGCM-generated background sea temperature for the generation of initial condition of the model. For the assessment of the assimilation impact, a comparative experiment has been done by integrating the model from different intial conditions: one from ARGO-, TAO-data assimilated initial condition and the other from background state without assimilation. The assimilated analysis field not only depicts major oceanic features more realistically but also reduces several systematic model bias that appear in every current OGCMs experiments. From the 10-month of model integrations with and without assimilated initial conditions, it is found that the major assimilated characteristics in sea temperature appeared in the initial field remain persistently throughout the integration. Such implies that the assimilated characteristics of the reduced sea temperature bias is to last in the integration without rapid restoration to the non-assimilated OGCM integration state by dispersing mass field in the form of internal gravity waves. From our analysis, it is concluded that the data assimilation method adapted in this study to MOM3 is reasonable and applicable with dynamical consistency. The success in generating initial condition with ARGO and TAO data assimilation has significant implication upon the prediction of the long-term climate and weather using ocean-atmosphere coupled model.

Association Between the GSTP1 Codon 105 Polymorphism and Gastric Cancer Risk: an Updated Meta-analysis

  • Bao, Li-Dao;Niu, Jian-Xiang;Song, Hui;Wang, Yi;Ma, Rui-Lian;Ren, Xian-Hua;Wu, Xin-Lin
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.8
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    • pp.3687-3693
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    • 2012
  • Objective: The current meta-analysis was performed to address a more accurate estimation of the association between glutathione S-transferase P1 (GSTP1) codon 105 polymorphism and risk of gastric cancer (GC), which has been widely reported with conflicting results. Methods: A comprehensive literature search was conducted to identify all the relevant studies. Fixed or random effect models were selected based on the heterogeneity test. Publication bias was estimated using Begg's funnel plots and Egger's regression test. Results: A total of 20 studies containing 2,821 GC cases and 6,240 controls were finally included in the analyses. Overall, no significant association between GSTP1 polymorphism and GC risk was observed in worldwide populations. However, subgroup analysis stratified by ethnicity showed that GSTP1 polymorphism was significantly associated with increased risk of GC in Asians (G vs. A, OR = 1.273, 95%CI=1.011-1.605; GG vs. AA, OR=2.103, 95%CI=1.197-3.387; GG vs. AA+AG, OR =2.103, 95%CI=1.186-3.414). In contrast, no significant association was found in Caucasians in any genetic models, except for with AG vs. AA (OR=0.791, 95%CI=0.669-0.936). Furthermore, the GSTP1 polymorphism was found to be significantly associated with GC in patients with H. pylori infection and in those with a cardiac GC. Subgroup analysis stratified by Lauren's classification and smoking status showed no significant association with any genetic model. No studies were found to significantly influence the pooled effects in each genetic mode, and no potential publication bias was detected. Conclusion: This meta-analysis suggested that the GSTP1 polymorphism might be associated with increased risk of GC in Asians, while GSTP1 heterozygote genotype seemed to be associated with reduced risk of GC. Since potential confounders could not be ruled out completely, further studies are needed to confirm these results.

Prediction of SWAT Stream Flow Using Only Future Precipitation Data (미래 강수량 자료만을 이용한 SWAT모형의 유출 예측)

  • Lee, Ji Min;Kum, Donghyuk;Kim, Young Sug;Kim, Yun Jung;Kang, Hyunwoo;Jang, Chun Hwa;Lee, Gwan Jae;Lim, Kyoung Jae
    • Journal of Korean Society on Water Environment
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    • v.29 no.1
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    • pp.88-96
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    • 2013
  • Much attention has been needed in water resource management at the watershed due to drought and flooding issues caused by climate change in recent years. Increase in air temperature and changes in precipitation patterns due to climate change are affecting hydrologic cycles, such as evaporation and soil moisture. Thus, these phenomena result in increased runoff at the watershed. The Soil and Water Assessment Tool (SWAT) model has been used to evaluate rainfall-runoff at the watershed reflecting effects on hydrology of various weather data such as rainfall, temperature, humidity, solar radiation, wind speed. For bias-correction of RCP data, at least 30 year data are needed. However, for most gaging stations, only precipitation data have been recorded and very little stations have recorded other weather data. In addition, the RCP scenario does not provide all weather data for the SWAT model. In this study, two scenarios were made to evaluate whether it would be possible to estimate streamflow using measured precipitation and long-term average values of other weather data required for running the SWAT. With measured long-term weather data (scenario 1) and with long-term average values of weather data except precipitation (scenario 2), the estimate streamflow values were almost the same with NSE value of 0.99. Increase/decrease by ${\pm}2%$, ${\pm}4%$ in temperature and humidity data did not affect streamflow. Thus, the RCP precipitation data for Hongcheon watershed were bias-corrected with measured long-term precipitation data to evaluate effects of climate change on streamflow. The results revealed that estimated streamflow for 2055s was the greatest among data for 2025s, 2055s, and 2085s. However, estimated streamflow for 2085s decreased by 9%. In addition, streamflow for Spring would be expected to increase compared with current data and streamflow for Summer will be decreased with RCP data. The results obtained in this study indicate that the streamflow could be estimated with long-term precipitation data only and effects of climate change could be evaluated using precipitation data as shown in this study.

Localization Using Extended Kalman Filter based on Chirp Spread Spectrum Ranging (확장 Kalman 필터를 적용한 첩 신호 대역확산 거리 측정 기반의 위치추정시스템)

  • Bae, Byoung-Chul;Nam, Yoon-Seok
    • Journal of the Institute of Electronics Engineers of Korea SC
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    • v.49 no.4
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    • pp.45-54
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    • 2012
  • Location-based services with GPS positioning technology as a key technology, but recognizing the current location through satellite communication is not possible in an indoor location-aware technology, low-power short-range communication is primarily made of the study. Especially, as Chirp Spread Spectrum(CSS) based location-aware approach for low-power physical layer IEEE802.15.4a is selected as a standard, Ranging distance estimation techniques and data transfer speed enhancements have been more developed. It is known that the distance measured by CSS ranging has quite a lot of noise as well as its bias. However, the noise problem can be adjusted by modeling the non-zero mean noise value by a scaling factor which corresponds to the change of magnitude of a measured distance vector. In this paper, we propose a localization system using the CSS signal to measure distance for a mobile node taken a measurement of the exact coordinates. By applying the extended kalman filter and least mean squares method, the localization system is faster, more stable. Finally, we evaluate the reliability and accuracy of the proposed algorithm's performance by the experiment for the realization of localization system.

A 12b 1kS/s 65uA 0.35um CMOS Algorithmic ADC for Sensor Interface in Ubiquitous Environments (유비쿼터스 환경에서의 센서 인터페이스를 위한 12비트 1kS/s 65uA 0.35um CMOS 알고리즈믹 A/D 변환기)

  • Lee, Myung-Hwan;Kim, Yong-Woo;Lee, Seung-Hoon
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.45 no.3
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    • pp.69-76
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    • 2008
  • This work proposes a 12b 1kS/s 65uA 0.35um CMOS algorithmic ADC for sensor interface applications such as accelerometers and gyro sensors requiring high resolution, ultra-low power, and small size simultaneously. The proposed ADC is based on an algorithmic architecture with recycling techniques to optimize sampling rate, resolution, chip area, and power consumption. Two versions of ADCs are fabricated with a conventional open-loop sampling scheme and a closed-loop sampling scheme to investigate the effects of offset and 1/f noise during dynamic operation. Switched bias power-reduction techniques and bias circuit sharing reduce the power consumption of amplifiers in the SHA and MDAC. The current and voltage references are implemented on chip with optional of-chip voltage references for low-power SoC applications. The prototype ADC in a 0.35um 2P4M CMOS technology demonstrates a measured DNL and INL within 0.78LSB and 2.24LSB, and shows a maximum SNDR and SFDR of 60dB and 70dB in versionl, and 63dB and 75dB in version2 at 1kS/s. The versionl and version2 ADCs with an active die area of $0.78mm^2$ and $0.81mm^2$ consume 0.163mW and 0.176mW at 1kS/s and 2.5V, respectively.

Controlling the Properties of Graphene using CVD Method: Pristine and N-doped Graphene (화학기상증착법을 이용한 그래핀의 물성 조절: 그래핀과 질소-도핑된 그래핀)

  • Park, Sang Jun;Lee, Imbok;Bae, Dong Jae;Nam, Jungtae;Park, Byung Jun;Han, Young Hee;Kim, Keun Soo
    • KEPCO Journal on Electric Power and Energy
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    • v.1 no.1
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    • pp.169-174
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    • 2015
  • In this research, pristine graphene was synthesized using methane ($CH_4$) gas, and N-doped graphene was synthesized using pyridine ($C_5H_5N$) liquid source by chemical vapor deposition (CVD) method. Basic optical properties of both pristine and N-doped graphene were investigated by Raman spectroscopy and XPS (X-ray photoemission spectroscopy), and electrical transport characteristics were estimated by current-voltage response of graphene channel as a function of gate voltages. Results for CVD grown pristine graphene from methane gas show that G-peak, 2D-peak and C1s-peak in Raman spectra and XPS. Charge neutral point (CNP; Dirac-point) appeared at about +4 V gate bias in electrical characterization. In the case of pyridine based CVD grown N-doped graphene, D-peak, G-peak, weak 2D-peak were observed in Raman spectra and C1s-peak and slight N1s-peak in XPS. CNP appeared at -96 V gate bias in electrical characterization. These result show successful control of the property of graphene artificially synthesized by CVD method.

A Meta-Analysis on Improvement in Locomotor Skills of Children with Disabilities by Physical Activity Programs (신체활동 프로그램 참여가 장애아동의 이동운동능력에 미치는 효과: 메타분석)

  • Han, Byum Suk;Lee, Tae Hee;Chun, Hea Ja
    • 재활복지
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    • v.20 no.3
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    • pp.83-104
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    • 2016
  • The purpose of this study was to identify improvement in locomotor skills by physical activity programs. Method of this study indicates that the current literature (2004-2015) were reviewed and the data from 24 studies with 518 disabled children were analyzed by using CMA3 (Comprehensive Meta-Analysis ver.3) program. Analyzing the data of the primary studies included gender, age, type of disabilities, duration of the physical activity program intervention(weeks, session per week, minutes per session), run, gallop, hop, leap, horizontal jump, and slide. For sensitivity analysis, publication bias and outlier were reviewed. Results of analysis indicates that the overall effect size of improvement in locomotor skills by physical activity programs was 1.143. There were large effect size in categorical analyses. Autistic spectrum among type of disabilities was 1.697 and run among 6 of locomotor skills was 1.019. 8~10 aged was 0.920 and the intervention of 100~120minutes(1.261)per session, 3sessions(1.078) per week, 16~20(1.587)weeks was found to be more larger than the others. In conclusion, improvement in locomotor skills by program participation showed that treated group was 37% more effective than control group.