• Title/Summary/Keyword: bi-groups

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The Measurement of the Magnitude of Sensory Perception and Displeasure to the Vibration Stimuli applied on Forearm in upper Limb Amputees (진동자극에 대한 상지 절단자의 전완부 감각 인지 크기와 불쾌감 측정)

  • Kim, Sol-Bi;Chang, Yun-Hee;Kim, Shin-Ki;Kim, Gyoo-Suk;Mun, Mu-Sung;Bae, Tae-Soo
    • Journal of the Korean Society for Precision Engineering
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    • v.29 no.7
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    • pp.705-710
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    • 2012
  • Research involving discomfort or pain related to haptic vibratory stimulation the for prosthesis users of myoelectrical hand is very lacking. Our objective of this study was to evaluate the displeasure and sensitivity of areas in forearm using vibration stimulation system between upper limb amputees and non-amputees. Twenty transradial amputees and forty non-amputees (20 youth, 20 elderly) were involved. We set up custom-made vibration stimulation system including eight actuators (4 medial parts and 4 lateral parts) and GUI-based acquisition system, to investigate changes of residual somatosensory sensibility and displeasure at proximal 25% of forearm. Eight vibration actuators were attached to the circumference of proximal 25% point of forearm at regular intervals. Sensitivity tests were used to stimulate the 120Hz and discomfort experiment was used to 37 ~ 223Hz. The subjective responses were evaluated by 10 point scale. The results showed that both groups were similar in sensitive areas. Response at around of radius was most sensitive than other areas in all subjects. Elderly group do not appear discomfort of vibrotactile; however, youth group and amputee presented discomfort of vibrotactile. Prosthesis with a vibrotactile feedback system should be developed considering the sensitivity. Furthermore, Future studies should investigate the scope of application of that principle.

Curcumin attenuates renal ischemia reperfusion injury via JNK pathway with the involvement of p300/CBP-mediated histone acetylation

  • Yang, Lu;Chen, Xiaoxiang;Bi, Zirong;Liao, Jun;Zhao, Weian;Huang, Wenqi
    • The Korean Journal of Physiology and Pharmacology
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    • v.25 no.5
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    • pp.413-423
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    • 2021
  • Apoptosis is proved responsible for renal damage during ischemia/reperfusion. The regulation for renal apoptosis induced by ischemia/reperfusion injury (IRI) has still been unclearly characterized to date. In the present study, we investigated the regulation of histone acetylation on IRI-induced renal apoptosis and the molecular mechanisms in rats with the application of curcumin possessing a variety of biological activities involving inhibition of apoptosis. Sprague-Dawley rats were randomized into four experimental groups (SHAM, IRI, curcumin, SP600125). Results showed that curcumin significantly decreased renal apoptosis and caspase-3/-9 expression and enhanced renal function in IRI rats. Treatment with curcumin in IRI rats also led to the decrease in expression of p300/cyclic AMP response element-binding protein (CBP) and activity of histone acetyltransferases (HATs). Reduced histone H3 lysine 9 (H3K9) acetylation was found near the promoter region of caspase-3/-9 after curcumin treatment. In a similar way, SP600125, an inhibitor of c-Jun N-terminal kinase (JNK), also attenuated renal apoptosis and enhanced renal function in IRI rats. In addition, SP600125 suppressed the binding level of p300/CBP and H3K9 acetylation near the promoter region of caspase-3/-9, and curcumin could inhibit JNK phosphorylation like SP600125. These results indicate that curcumin could attenuate renal IRI via JNK/p300/CBP-mediated anti-apoptosis signaling.

3D printing technology and its applications in the future food industry: a review (3D 프린팅 기술과 미래식품산업의 응용)

  • Yoon, Hyung-Sun;Lee, Mihyun;Jin, Xuanyan;Kim, Su-Jin;Lee, Soyeon;Kim, Yeon-Bi;You, Young-Sun;Rhee, Jin-Kyu
    • Food Science and Industry
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    • v.49 no.4
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    • pp.64-69
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    • 2016
  • The potentialities of 3D printing technology are discussed from technical and research-oriented perspectives for industrial manufacturing of a variety of food products. Currently, 3D printing technology has advanced to enable us to process or cook innovative foods. However, food-based materials for 3D printing are still limited in terms of eating qualities, nutritional values and functionality as well as industrial production. Therefore, this uprising issue on alternative food processing techniques especially focused on the exploration of new food materials combined with these 3D printing technologies needs to be re-spotlighted, and then solved to pave the way to this innovative and sensational area of investigation with more accessibility. In this review, previous research work and industrial applications conducted by frontier research groups in this field are covered, then to open discussion for future research on the 3D printing of food.

Quality and Antioxidant Activity of Soybean Curd Supplemented with Codium fragile (청각(Codium fragile)을 첨가하여 제조한 두부의 품질특성 및 항산화 활성)

  • Choi, Man-Seok;Jeon, Eun Bi;Kim, Ji Yoon;Park, Shin Young
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.53 no.6
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    • pp.816-822
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    • 2020
  • This study investigated the antioxidant activity and general and sensory properties of soybean curd supplemented with Codium fragile. The yield of soybean curd containing 0%, 20%, and 40% C. fragile was 113.62, 104.09, and 108.06, respectively. Antioxidant activities and pH were significantly increased (P<0.05) depending on the amount of C. fragile supplemented in soybean curd. Compared to that in additive-free soybean curd (control), the amount of crude ash and protein in soybean curd containing 40% C. fragile was significantly decreased (P<0.05) and increased (P<0.05), respectively. We observed a dose-dependent increase (P<0.05) in the hardness and chewiness of soybean curd concomitant with the amount of C. fragile supplemented. In contrast, we observed no significant difference (P>0.05) in soybean curd's cohesiveness between the groups. As determined by sensory evaluation based on seven-point hedonic scale, soybean curd supplemented with 20% C. fragile received an excellent score (6.55) for color. As the same method, we observed that the flavor and overall acceptability significantly increased (P<0.05) in the C. fragile content increased. Taken together, the antioxidant and sensory assays in our study make a compelling case for the practical development of soybean curd supplemented with C. fragile owing to its good antioxidant activities, general properties, and consumer acceptance.

MRI Features for Prediction Malignant Intra-Mammary Lymph Nodes: Correlations with Mammography and Ultrasound

  • Kim, Meejung;Kang, Bong Joo;Park, Ga Eun
    • Investigative Magnetic Resonance Imaging
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    • v.26 no.2
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    • pp.135-149
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    • 2022
  • Purpose: To assess clinically significant imaging findings of malignant intramammary lymph nodes (IMLNs) in breast cancer patients and to evaluate their diagnostic performance in predicting malignant IMLN. Materials and Methods: A total of 110 cases with IMLN of BI-RADS category 3 or more, not typical benign IMLN, in MR of breast cancer patients between January 2016 and January 2021 were retrospectively reviewed. After excluding 33 cases, 77 cases were finally included. Among them, 58 and 19 were confirmed as benign and malignant, respectively. Qualitative and quantitative MR imaging features of the IMLN were retrospectively analyzed. Sizes and final assessment categories of IMLN on MRI, mammography, and ultrasound were reviewed. Diagnostic performances of imaging features on MRI, mammography, and ultrasound were then evaluated. Results: For qualitative MR features, shape, margin, and preserved central hilum were significantly different between benign and malignant groups (P < 0.05). For quantitative MR features, long diameter over 6 mm, short diameter over 4 mm, and cortical thickening over 3 mm showed high sensitivities in predicting malignant IMLNs (89.5%, 94.7%, and 100%, respectively). Size exceeding 1 cm showed high specificity and accuracy in predicting malignant IMLN on MR, mammography, and ultrasound (91.4% and 80.5%; 96.6% and 79.25; 98.3% and 80.5%, respectively). Conclusion: Various MR imaging features and size can be helpful for predicting malignant IMLN in breast cancer patients.

Genetic study of quantitative traits supports the use of Guzera as dual-purpose cattle

  • Carrara, Eula Regina;Peixoto, Maria Gabriela Campolina Diniz;Veroneze, Renata;Silva, Fabyano Fonseca e;Ramos, Pedro Vital Brasil;Bruneli, Frank Angelo Tomita;Zadra, Lenira El Faro;Ventura, Henrique Torres;Josahkian, Luiz Antonio;Lopes, Paulo Savio
    • Animal Bioscience
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    • v.35 no.7
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    • pp.955-963
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    • 2022
  • Objective: The aim of this study was to estimate genetic parameters for 305-day cumulative milk yield and components, growth, and reproductive traits in Guzerá cattle. Methods: The evaluated traits were 305-day first-lactation cumulative yields (kg) of milk (MY305), fat (FY305), protein (PY305), lactose (LY305), and total solids (SY305); age at first calving (AFC) in days; adjusted scrotal perimeter (cm) at the ages of 365 (SP365) and 450 (SP450) days; and adjusted body weight (kg) at the ages of 210 (W210), 365 (W365), and 450 (W450) days. The (co)variance components were estimated using the restricted maximum likelihood method for single-trait, bi-trait and tri-trait analyses. Contemporary groups and additive genetic effects were included in the general mixed model. Maternal genetic and permanent environmental effects were also included for W210. Results: The direct heritability estimates ranged from 0.16 (W210) to 0.32 (MY305). The maternal heritability estimate for W210 was 0.03. Genetic correlation estimates among milk production traits and growth traits ranged from 0.92 to 0.99 and from 0.92 to 0.99, respectively. For milk production and growth traits, the genetic correlations ranged from 0.33 to 0.56. The genetic correlations among AFC and all other traits were negative (-0.43 to -0.27). Scrotal perimeter traits and body weights showed genetic correlations ranging from 0.41 to 0.46, and scrotal perimeter and milk production traits showed genetic correlations ranging from 0.11 to 0.30. The phenotypic correlations were similar in direction (same sign) and lower than the corresponding genetic correlations. Conclusion: These results suggest the viability and potential of joint selection for dairy and beef traits in Guzerá cattle, taking into account reproductive traits.

A preliminary study on the relation of Uterine myoma focusing on General symptom (일반 증상을 중심으로 한 자궁근종 관련성에 대한 예비 연구)

  • Yoon, Young-Jin;Jang, Jun-Bock;Cho, Jung-Hoo;Lee, Jin-Moo;Lee, Chang-Hoon;Lee, Kyung-Sub
    • The Journal of Korean Obstetrics and Gynecology
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    • v.22 no.1
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    • pp.161-171
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    • 2009
  • Purpose: We intended to observe relation between general symptom and the number of uterine myoma. Methods: We surveyed 948 women from 35 to 45 years old who had received Korean oriental medical questionnaires about general symptom pattern and pelvic ultrasonography at Kyung-Hee university medical center from May, 2007 to October, 2008. After we divided women into three groups (Mono-uterine myoma, Bi-uterine myoma & uterine myoma above 3) by ultrasonography result, we compared general symptom pattern according to the number of uterine myoma. For statistics, we used Kruskal-Wallis Test, SPSS 13.0 for windows. Results: In relation to sleep pattern, severity of dreaming & awaking showed statistical significance according to the number of uterine myoma. In relation to digestion pattern, appetite & heartburn showed statistical significance according to the number of uterine myoma. In relation to evacuation pattern, hardening of stool showed statistical significance according to the number of uterine myoma. In relation to sweating pattern, severity of refreshing after sweating showed statistical significance according to the number of uterine myoma. In relation to the other patterns, hypertonicity of nape neck showed statistical significance according to the number of uterine myoma(p<0.05). Conclusion: The result showed that prevalence of uterine myoma had to be considered in respect of sleep, digestion, evacuation and sweating pattern. we need further study based on this preliminary result.

The development of buoy type fish finder using LTE communication (LTE 통신을 이용한 부표형 어군탐지기 개발)

  • KANG, Tae-Jong;MIN, Eun-Bi;HEO, Gyeom;SHIN, Hyeon-Ok;HWANG, Doo-Jin
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.58 no.2
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    • pp.141-152
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    • 2022
  • As a method to understand the ecological habits around the artificial reef, various reports such as fishing gear survey, diving, sound survey, underwater CCTV and camera, etc. are reported. Among them, the sound survey method is carried out by installing an acoustic system on the ship and can be investigated regardless of the marine environment such as time constraints and turbidity. Such method, however, takes a lot of manpower and time as the ship travels at a constant speed. Investigations around artificial reefs are being conducted in an artificial way, and a lot of time and labor are consumed as such. Maritime buoys have been operated for various purposes such as route signs, weather observation, marine environment monitoring and defense monitoring for navigation safety in the past, but studies on monitoring systems for ecological habits and distribution of fish using marine buoys are remarkably insufficient. Therefore, this study aims to develop a system that allows users to directly monitor fish group detector data by estimating the distribution of fish groups around artificial reefs and using wireless communication at sea. In order to confirm the suitability of the maritime buoy used in this study, it was operated to compare data using LTE-equipped buoys capable of wireless communication and a data logger-type system buoy. Data transmission of buoys capable of LTE communication was carried out in a 10-minute ON, 10-minute OFF method due to the limitation of the power supply capacity, and data of the data logger-type buoy received full data. We compared and analyzed the data received from the two fish detectors. It is expected that real-time monitoring of the wireless buoy detection device using LTE will be possible through future research.

Design of the emotion expression in multimodal conversation interaction of companion robot (컴패니언 로봇의 멀티 모달 대화 인터랙션에서의 감정 표현 디자인 연구)

  • Lee, Seul Bi;Yoo, Seung Hun
    • Design Convergence Study
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    • v.16 no.6
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    • pp.137-152
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    • 2017
  • This research aims to develop the companion robot experience design for elderly in korea based on needs-function deploy matrix of robot and emotion expression research of robot in multimodal interaction. First, Elder users' main needs were categorized into 4 groups based on ethnographic research. Second, the functional elements and physical actuators of robot were mapped to user needs in function- needs deploy matrix. The final UX design prototype was implemented with a robot type that has a verbal non-touch multi modal interface with emotional facial expression based on Ekman's Facial Action Coding System (FACS). The proposed robot prototype was validated through a user test session to analyze the influence of the robot interaction on the cognition and emotion of users by Story Recall Test and face emotion analysis software; Emotion API when the robot changes facial expression corresponds to the emotion of the delivered information by the robot and when the robot initiated interaction cycle voluntarily. The group with emotional robot showed a relatively high recall rate in the delayed recall test and In the facial expression analysis, the facial expression and the interaction initiation of the robot affected on emotion and preference of the elderly participants.

Fluid Inclusion Studies on the Wolak Tungsten-Molybdenum Deposits, Korea (월악 중석-몰리브덴 광상의 유체포유물 연구)

  • Lee, In Sung;Park, Hee-In
    • Economic and Environmental Geology
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    • v.15 no.1
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    • pp.17-32
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    • 1982
  • The Wolak tungsten-molybdenum deposits are tungsten-molybdenum bearing quartz veins which filled the fractures in Pre-Cambrian pebble-bearing calcareous hornfels, hornfels and Cretaceous granite. There are two vein groups in this mine, Dongsan vein group in the west and Kwangcheon vein group in the east. The ore minerals are wolframite, scheelite, molybdenite, native bismuth, bismuthinite, pyrite, arsenopyrite, chalcopyrite, cubanite, stannite, pyrrhotite, sphalerite, galena, marcasite, Pb-Bi sulfosalt and ilmenite. Quartz, calcite, beryl, fluorite, muscovite, rhodochrosite and siderite are gangue minerals. Fluid inclusion studies were carried out for the quartz, beryl, scheelite, early and late fluorite. Fluid inclusion studies reveal that liquid-gas inclusions are most common and occur in all of the minerals examined. Filling degree of the inclusions in the late fluorite is much higher than that of the inclusions in quartz and early fluorite. Liquid $CO_2$ bearing liquid-gas inclusions occur in quartz and early fluorite. Liquid, gas and solid phase inclusions occur in quartz, beryl and scheelite. Salinities of inclusions in quartz and beryl from Dongsan vein group range from 3.9 to 8.0, from 5.3 to 7.7 wt.% NaCl equivalent respectively. Salinities in the late fluorite range from 1.5 to 3.2 wt.% NaCl equivalent. In Kwangcheon vein group salinities range from 3.9 to 9.6 wt.% NaCl equivalent in quartz, from 2.8 to 7.3 wt.% NaCl equivalent in early fluorite, from 1.3 to 1.5 wt.% NaCl equivalent in late fluorite. Homogenization temperatures of inclusions range from $239^{\circ}$ to higher than $360^{\circ}C$ in quartz, over $360^{\circ}C$ in scheelite, from $288^{\circ}C$ to higher than $360^{\circ}C$ in beryl, and from $159^{\circ}$ to $202^{\circ}C$ in late fluorite of the Dongsan vein group. In Kwangcheon vein group, homo genization temperatures of inclusions range from $240^{\circ}C$ to higher than $360^{\circ}C$ in quartz and from $240^{\circ}$ to $328^{\circ}C$ in early fluorite. As a whole, in Dongsan and Kwangcheon vein groups it seems that there are no distinct differences in mineralogy, salinities and homogenization temperatures. No distinct variations in homogenization temperatures are revealed through about 300 m vertically in both district. The faint trend of increase in salinities in the lower level can be detected. The salinity, $CO_2$ content and the temperature of ore fluid were much higher in the early vein stage and then dropped off in the late stage of mineralization as represented by the quartz and fluorite inclusion data.

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