• The Korean Journal of Pesticide Science
• /
• v.6 no.2
• /
• pp.105-109
• /
• 2002

Synthetic method of a new benzoylphenylurea insecticide, DBI-3204 [1-(2,6-Difluorobenzoyl)-3-(3,5-bistrifluoromethyl-2-chlorophenyl) urea] was established for manufactural production; 2,6-Difluorobenzoylisocyanate was synthesized by the reaction of 2,6-difluorobenzamide with oxalylchloride in 95% yields, the reaction of 3,5-bis(trifluoromethyl)aniline with N-chlorosuccinimde gave 3,5-bis (trifluoromethyl)-2-chloroaniline in 92% yields, and DBI-3204 was got from 2,6-difluorobenzoylisocyanate and 3,5-bis(trifluoromethyl)-2-chloroaniline in 90% yields. All the process was simplified by using the same reaction solvent, carbontetrachloride.

• The Korean Journal of Pesticide Science
• /
• v.4 no.2
• /
• pp.63-68
• /
• 2000

This study was conducted to investigate insecticidal mechanisms of the new insecticides DBI-1015 and DBI-3204 with label compounds of chitin precursors, [$^{14}C$] N-acetylglucosamine and [$^{14}C$] UDP-N-acetylglucosamine in Spodoptera litura. The concentrations of the insecticides for incorporation of chitin precursors into chitin were founded to be functional relationship. The result of in vivo test, $I_{50}$ (ppm) of the DBI-1015, DBI-3024 and diflubenzuron to [$^{14}C$] N-acetylglucosamine were 0.57, 0.89 and 0.26 ppm respectively, and to [$^{14}C$] UDP-N-acetylglucosaminen were 0.99, 0.53 and 0.45 ppm respectively. in vitro test of DBI-1015, DBI-3024 and diflubenzuron by integument fragments, the incorporation rate in the cuticle were low, however, $40{\sim}60%$ inhibitions were observed at $2{\mu}M$ when compared to the untreated control.