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A Clinical Study of Parotid Gland Tumors (이하선 종양의 임상적고찰)

  • JeGal Young-Jong;Choi Wone
    • Korean Journal of Head & Neck Oncology
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    • v.2 no.1
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    • pp.33-39
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    • 1986
  • This is a clinical analysis of 24 cases of parotid gland tumor who were treated in the department of Surgery, Chonnam National University Medical School during the past 10years from January, 1976 to December, 1985. According to this analysis of total 24 cases, we concluded as follows; 1) 21 cases were benign tumors and 3 cases were malignant tumors. As the histopathological findings, benign tumor included 88%and malignant tumor 12%. Majority of benign tumor contained mixed tumor(86.7%), and the malignant tumor contained mucoepidermoid carcinoma (66.7%). 2) The peak age incidence was 40th in benign tumor and 50th in malignant tumor. 3) The chief complaints of patient was a painless mass and the duration of illness was average 5.2 years. 4) The mean size of mass was 4.5cm in diameter. 5) The surgical procedures were performed with excision 6 cases, superficial lobectomy 8 cases, wide excision with partial parotidectomy 4 cases, total parotidectomy 3 cases in benign tumors. In malignant tumors, total parotidectomy 2 cases and wide excision with partial parotidectomy 1 case were performed. 6) Major postoperative complications such as facial nerve palsy 7 cases (temporary ; 5 cases, permanent; 2 cases), Frey syndrome 1 case, seroma 1 case, hematoma 1 case, and wound infection 1 case were developed. The recurrence contained pleomorphic adenoma 1 case and mucoepidermoid carcinoma 1 case.

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Development of a Basic Standard Tool for Pattern Identification of Benign Prostatic Hyperplasia (BPH) (전립선비대증 변증도구 개발 기초 연구)

  • Jeong, Ho-young;Lee, Ji-yoon;Park, Yang-chun;Jung, In-chul;Cho, Chung-sik
    • The Journal of Internal Korean Medicine
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    • v.38 no.3
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    • pp.301-318
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    • 2017
  • Objective: The purpose of this study was to develop a standard tool of pattern identification, which will be applied to clinical research, for benign prostatic hyperplasia. Method: The items and structure of the instrument were based on a review of the published literature in China and Korea. The advisory committee on this study included 11 kidney-endocrine professors of the Korean Medical Colleges Division and 4 Korean medicine doctors who had a doctor's degree in the Kidney-Endocrine Division. The advisory committee was questioned regarding pattern identification importance, symptom weight, treatment importance, changes in the symptoms, rare changes in the symptoms, and frequency of prescriptions regarding benign prostatic hyperplasia. Results: The Korean instrument of pattern identification was completed; it was composed of four questions for benign prostatic hyperplasia. Conclusion: We sincerely look forward to improving the instrument through the continuous clinical studies.

Knowledge of Human Papillomavirus and its Association with Head and Neck Benign and Malignant Lesions in a Group of Dental Patients in Pakistan

  • Gichki, Abdul Samad;Buajeeb, Waranun;Doungudomdacha, Sombhun;Khovidhunkit, Siribang-On Pibooniyom
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.4
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    • pp.1581-1585
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    • 2015
  • Human papillomaviruses (HPVs) remain a serious world health problem due to their association with cervical and head and neck cancers. While over 100 HPV types have been identified, only a few subtypes are associated with malignancies. HPV 16 and 18 are the most prevalent oncogenic types in head and neck cancers. Although it has been proven that some subsets of benign and malignant head and neck lesions are associated with HPV, the general population have very little awareness and knowledge of their association with HPV. Therefore, the purpose of this study was to determine the knowledge of HPV and its links with head and neck benign and malignant lesions in a group of Pakistani dental patients who attended the Dental Department of the Sandeman provincial hospital in Quetta, Pakistan. One hundred and ninety-two patients were recruited and requested to answer a questionnaire. It was revealed that there was a low level of knowledge about HPV and its association with head and neck benign and malignant lesions among the participants. This result suggested that more education regarding the relationship of HPV in inducing head and neck benign and malignant lesions is required in this group of patients.

Improved Diagnostic Accuracy in Characterization of Adnexal Masses by Detection of Choline Peak Using 1H MR Spectroscopy in Comparison to Internal Reference at 3 Tesla

  • Malek, Mahrooz;Pourashraf, Maryam;Gilani, Mitra Modares;Gity, Masoumeh
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.12
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    • pp.5085-5088
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    • 2015
  • Background: The aim of this study was to assess the role of the presence of a choline peak in 3 Tesla 1H magnetic resonance spectroscopy (MRS) for differentiating benign from malignant adnexal masses. Materials and Methods: A total of 46 adnexal masses (23 malignant and 23 benign) underwent 1H MRS study prior to surgery to assess the presence of choline peak. Results: A choline peak was detected in 16 malignant masses (69.5%) and was absent in the other 7 (30.5%). A choline peak was only detected in 6 (26%) of the benign adnexal masses. The presence of an MRS choline peak had a sensitivity of 69.5%, a specificity of 74%, a positive predictive value (PPV) of 72.7%, and a negative predictive value (NPV) of 71% for diagnosing malignant adnexal masses. A significant difference between the frequency of mean choline peaks in benign and malignant adnexal masses was observed (P value < 0.01). Conclusions: A 1H MRS choline peak is seen in malignant adnexal masses more frequently than the benign masses, and may be helpful for diagnosing malignant adnexal masses.

Clinicopathological Evaluation of Odontogenic Tumours in Pakistan - A Seven Years Retrospective Study

  • Naz, Iram;Mahmood, Muhammad Khurram;Akhtar, Farhan;Nagi, Abdul Hannan
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.7
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    • pp.3327-3330
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    • 2014
  • Background: The purpose of the study was to analyse the clinicopathological spectrum of benign and malignant odontogenic tumours (OT) in Pakistan. Materials and Methods: This retrospective study was carried out at the Armed Forces Institute of Pathology (AFIP) Rawalpindi. Seven years archival records of histologically diagnosed odontogenic tumours, both benign and malignant, were collected and the lesions re-diagnosed histologically in accordance with the WHO classification of head and neck tumours (2005). Clinical as well as histological data were analysed and frequency of each type of OT was calculated using computer software programme SPSS (version 17). Mean tumour size was calculated and Chi-square test was applied to find associations of age, gender and site with each histological type of tumour. Results: Only 1.7% of the odontogenic tumours diagnosed in this said period were malignant while the remaining 98.3% were benign. Amongst benign lesions, ameloblastoma was the most common (61.3%) type while primary intraosseous squamous cell carcinoma (1.7%) was the only reported malignant tumour. Mean age of the affected patients was $31.7{\pm}16.7$ years with posterior mandible as the commonest site involved. Conclusions: Our study revealed ameloblastoma and primary intraosseous squamous cell carcinoma as the commonest diagnosed benign and malignant tumours respectively. There was a significant difference in age and site of origin of different types of OT at the time of their presentation. However, all the tumours showed male predominance.

Case of Combined Eastern-Western Medicine Treatment on a Patient Diagnosed with Benign Paroxysmal Positional Vertigo after Acute Vestibular Neuritis (양성 돌발성 체위 현훈으로 이행된 급성 전정신경염 환자의 한양방 협진 치료 1례)

  • Park, Young-hwa;Lim, Bo-ra;Ok, Hyo-joon;Sun, Jong-joo;Park, Joon-ha
    • The Journal of Internal Korean Medicine
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    • v.37 no.2
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    • pp.273-282
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    • 2016
  • Objective: This clinical study was performed with a female patient to evaluate the effects of combined Eastern-Western medicine treatment on benign paroxysmal positional vertigo after acute vestibular neuritis.Method: We used acupuncture, herbal medication, Western medication, fluid therapy, and the canalith repositioning maneuver to treat a female patient suffering from dizzy spells. The vertigo scale was checked to assess any improvement in symptoms.Results: The patient had originally recovered from acute vestibular neuritis, but after the first discharge, she came down with benign paroxysmal positional vertigo and had to be rehospitalized. She eventually got better, however, and her score on the vertigo scale improved.Conclusion: This study demonstrates that combined Eastern-Western medicine treatment may be an effective option for treating benign paroxysmal positional vertigo after acute vestibular neuritis, despite the difficulty of the treatment in this case.

Levels of Serum 25-Hydroxy-Vitamin D in Benign and Malignant Breast Masses

  • Alipour, Sadaf;Hadji, Maryam;Hosseini, Ladan;Omranipour, Ramesh;Saberi, Azin;Seifollahi, Akram;Bayani, Leila;Shirzad, Nooshin
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.1
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    • pp.129-132
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    • 2014
  • Background: The true association between breast cancer and vitamin D is currently under investigation. We compared serum 25-hydroxy-vitamin D levels in women with benign and malignant breast masses and controls. Materials and Methods: Levels of vitamin D were measured by electrochemiluminescense. Serum levels >35 ng/ml, 25-35 ng/ml, 12.5-25 ng/ml and <12.5 ng/ml were considered as normal, mild, moderate and severe vitamin D deficiency, respectively. Results: Overall, 364 women were included in the control, 172 in the benign and 136 in the malignant groups. The median serum vitamin D level was significantly lower in breast cancers than controls. Levels were also lower in malignant than benign cases and in benign cases than controls although statistically non-significant. Conclusions: Multinomial logistic regression analysis showed that severe vitamin D deficiency causes a three-fold increase in the risk of breast cancer while this was not the case for moderate and mild deficiency.

A Case of Benign Metastasizing Pulmonary Leiomyomatosis (양성 전이성 폐 평활근종증 1예)

  • Kim, Youn-Seup;Kim, Eo-Jin;Park, Coong-Hak;Park, Jae-Seuk;Jee, Young-Koo;Lee, Kye-Young
    • Tuberculosis and Respiratory Diseases
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    • v.53 no.2
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    • pp.190-195
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    • 2002
  • A benign metastasizing pulmonary leiomyomatosis(BMPL) is a rare and uncommon variety of leiomyoma. BML affects middle-aged women who had a previous hysterectomy due to a histologically benign appearing leiomyoma. BMPL is characterized by asymptomatic multiple smooth muscle nodules with a less aggressive course than a leiomyosarcoma. A 45-year-old woman who had a hysterectomy for a uterine leiomyoma 4 years prior to this study presented with multiple variable-sized lung nodule. A percutaneous needle biopsy confirmed the benign metastasizing pulmonary leiomyomatosis. Here, we present this case with a review of the relevant literatures.

Concurrent Thyroid Carcinoma and Benign Thyroid Disease (양성 갑상선질환과 함께 나타나는 갑상선암)

  • Chung So-Hwan;Yoon Jung-Han;JaeGal Young-Jong
    • Korean Journal of Head & Neck Oncology
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    • v.14 no.1
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    • pp.88-93
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    • 1998
  • In order to review the clinicopathologic characteristics of the thyroid cancer associated with benign thyroid disease, we evaluated 47 patients treated between January, 1993 and September, 1997 at the Chonnam National University Hospital. In those period, we had operated a total of 690 thyroidectomy of which 320 were diagnosed as thyroid cancer. Forty three(91.4%)occurred in women and four(8.5%)occurred in men. The mean age at operation was 46.7years(range, 15 to 76 years). Forty three of the 47 cancers(91.4%) were papillary carcinomas while 4(8.5%)were follicular. Twenty four of the 47 patients (51%) were occult thyroid carcinomas measured less than 1 cm in diameter. The concurrent benign disease were nodular goiter(n=17), Hashimoto's thyroiditis(n=16), follicular adenoma(n=10), Graves' disease(n=2) and diffuse hyperplasia(n=2). Thirty one patients were diagnosed by preoperative FNAC and they underwent total thyroidectomy. Three were diagnosed by frozen section examination at the time of operation. Among them, one underwent total thyroidectomy and two underwent subtotal thyroidectomy. Eight cases revealed lymph node metastases and 2 cases extended to surrounding muscles. In conclusion, concurrent thyroid cancers and benign thyroid disease are not uncommon and a regular ultrasonic follow-up with selective aspiration cytologic examination is recommaned to enhance their diagnostic accuracy.

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Benign Clear Cell Tumor of the Lung -Report of a case- (폐에 발생한 양성 투명세포종 -치험 1례 보고-)

  • Lim, Cheong;Kim, Kwhan-mien;Sung, Sook-whan;Kim, Joo-Hyun
    • Journal of Chest Surgery
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    • v.28 no.9
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    • pp.861-864
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    • 1995
  • We experienced a case of benign clear cell tumor, a very rare form of lung tumor. A forty-year-old male complained of non-specific right flank pain for 1 month prior to admission. Under the suspicion of a benign lesion, an exploratory thoracotomy was done. Since the first case was reported in 1963 by Leibow and Castleman, about 40 cases have been reported worldwide by 1993. Basically it was believed to be a benign lesion but in certain cases, it showed malignant behavior. Simple surgical excision is satisfactory to this benign lesion. But close long-term follow up is mandatory. We report this first case in Korea with the review of literature.

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