• Journal of Chest Surgery
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• 제28권9호
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• pp.861-864
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• 1995

We experienced a case of benign clear cell tumor, a very rare form of lung tumor. A forty-year-old male complained of non-specific right flank pain for 1 month prior to admission. Under the suspicion of a benign lesion, an exploratory thoracotomy was done. Since the first case was reported in 1963 by Leibow and Castleman, about 40 cases have been reported worldwide by 1993. Basically it was believed to be a benign lesion but in certain cases, it showed malignant behavior. Simple surgical excision is satisfactory to this benign lesion. But close long-term follow up is mandatory. We report this first case in Korea with the review of literature.

• Journal of Chest Surgery
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• 제4권2호
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• pp.91-94
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• 1971

Benign papillary tumors commonly arise in the upper respiratory tract but are rare in the lower respiratory tract, especially in the bronchi. Solitary benign papillary tumors arising at the bronchi,covered with stratified squamous epithelium and associated with little or no inflammatory cell response,seem to be rarest of all types of benign bronchial tumors. Only six cases of such tumors had been reported in the medical literature over the past 74 years until 1968. The following is a case report of solitary benign papilloma arising at the opening of the left main bronchus which was treated with bronchoscopic removal at Chest Surgery Depariment, N.M.C. on Sept.

• 대한두경부종양학회지
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• 제19권2호
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• pp.175-178
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• 2003

Benign lymphoepithelial cysts of parotid gland were first described by Miculicz in 1888, have been presented for a long time, uncommonly. But, recently it has been reported with increasing frequency since the onset of human immunodeficiency virus (HIV) infection. Benign lymphoepithelial cysts can be diagnosed by the fine needle aspiration in conjunction with the history and physical examination. The therapeutic options of benign lymphoepithelial cysts have been limited to aspiration, surgical resection, medical therapy, radiotherapy and sclerotherapy. Recently, we experienced a case of benign lymphoepithelial cyst of right parotid gland, so we report this case with review of the literatures.

• 대한후두음성언어의학회지
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• 제26권2호
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• pp.94-96
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• 2015

Several distinct pathologic entities are encompassed in benign vocal fold lesions, including intracordal cysts, vascular ectasia, as well as vocal fold nodules and vocal fold polyps. Treatment options for theses lesions include both medical/conservative and surgical techniques. First approaches should be focus on correcting the underlying causative factors, largely through voice therapy and education. There are several laryngomicrosurgery techniques for removal of benign lesions. Much debate continues regarding the relative merits of cold instruments versus carbon dioxide laser removal of benign vocal fold lesions. Both techniques have the merits and the demerits each other. Therefore the surgeon should well comprehend the merits of each techniques and choose the proper procedure for patient's lesions.

• 대한세포병리학회지
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• 제11권2호
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• pp.75-81
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• 2000

Cathepsin D is a protease which is known to facilitate invasion and metastasis of breast carcinoma. Overexpression of cathepsin D is associated with poor clinical outcome and biologic aggressiveness of the breast cancer. We underwent immunocytochemical assay(ICA) for cathepsin D in fine needle aspiration cytology(FNAC) specimens from the breast carcinoma and benign breast diseases. In FNAC specimens cathepsin D was expressed in 21(42.9%) out of 49 cases of invasive ductal carcinoma, whereas negative result was observed in all 15 cases of benign breast diseases including 7 fibroadenomas, 6 fibrocystic diseases, and 2 benign ductal hyperplasias. Among the 11 FNAC specimens from ductal carcinoma in situ(DCIS), cathepsin D was expressed in 3 cases(27.3%). In FNAC specimens immunocytochemistry for cathepsin D showed positive result in 24 out of 60 carcinomas(sensitivity, 40%) and negative result in 15 out of all 15 benign breast diseases(specificity, 100%). No significant correlation was noted between cathepsin D expression in FNAC specimen and clinicohistological characteristics of the breast carcinoma, such as hormone receptors and cell differentiation. In conclusion, ICA of cathepsin D in FNAC specimens thought to be a good adjunct to differentiate malignancy from benign breast diseases.

• 대한골관절종양학회지
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• 제6권4호
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• pp.168-172
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• 2000

양성 연부조직 간엽세포종은 최소한 두개 이상의 간엽세포조직이 한 종물에 포함된 종양으로 이들 조직세포들은 흔히 같이 발견되지 않는 것들이다. 전세계적으로 적은 수의 양성 간엽 세포종이 보고되고 있으며, 특히 연골 세포 조직이 주를 이루는 경우는 극히 드문 경우로 현재까지 보고된 11개의 증례가 문헌에 보고되고 있다. 저자는 3세 유아에서 흉추 배부에 발생한 연골세포가 주성분으로 구성된 양성 간엽세포종을 경험한 바 고찰과 함께 보고하는 바이다.

• Asian Pacific Journal of Cancer Prevention
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• 제15권13호
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• pp.5123-5126
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• 2014

Background: To evaluate the diagnostic performance of IOTA simple rules in differentiating between benign and malignant ovarian tumors. Materials and Methods: A study of diagnostic performance was conducted on women scheduled for elective surgery due to ovarian masses between March 2007 and March 2012. All patients underwent ultrasound examination for IOTA simple rules within 24 hours of surgery. All examinations were performed by the authors, who had no any clinical information of the patients, to differentiate between benign and malignant adnexal masses using IOTA simple rules. Gold standard diagnosis was based on pathological or operative findings. Results: A total of 398 adnexal masses, in 376 women, were available for analysis. Of them, the IOTA simple rules could be applied in 319 (80.1%) including 212 (66.5%) benign tumors and 107 (33.6%) malignant tumors. The simple rules yielded inconclusive results in 79 (19.9%) masses. In the 319 masses for which the IOTA simple rules could be applied, sensitivity was 82.9% and specificity 95.3%. Conclusions: The IOTA simple rules have high diagnostic performance in differentiating between benign and malignant adnexal masses. Nevertheless, inconclusive results are relatively common.

• 대한후두음성언어의학회지
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• 제13권1호
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• pp.40-44
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• 2002

Background and Objectives : Vocal abuse and misuse and muscle tension dysphonia that have various movements of false vocal folds may be related to the development of benign vocal folds lesions, such as vocal nodules, polyps, and cysts. This study was designed to determine whether benign vocal folds lesions were related with movements of false vocal folds on phonation. Material and Methods : One Hundred and seventy eight subjects were studied. All subjects received otolaryngological evaluation including videostroboscopy, objective voice measures. Patients were diagnosed as normal shape of vocal folds (group a), approximation of bilateral false vocal folds (group b), approximation of unilateral false vocal folds (group c), lateralized extension of false vocal folds (group d), and medialized approximation of posterior false vocal folds (group e). We analyzed the results of benign vocal folds lesions in each group. Results : Differences were found between the normal shaped group and the abnormal shaped group. No differences were found between each abnormal groups except group d and e. Conclusion : The shape of false vocal folds was related to the benign vocal folds lesions.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제22권6호
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• pp.565-570
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• 2019

Benign biliary strictures are uncommon in children. Classically, these cases are managed surgically, however less invasive approaches with interventional radiology and or endoscopy may have similar results and improved safety profiles While benign biliary strictures have been described in literature on several occasions in young children, (most older than 1 year and once in an infant 3 months of age), all reported cases were managed surgically. We present two cases of benign biliary strictures in infants less than 6 months of age that were managed successfully with novel non-invasive procedures and a review of all current pediatric cases reported in the literature. Furthermore, we describe the use of a Rendezvous procedure, which has not been reported as a treatment approach for benign biliary strictures.

• 대한기관식도과학회지
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• 제4권1호
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• pp.79-84
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• 1998

Benign symmetric lipomatosis was initially described in 1846 by Sir Benjamin Brodie. In 1888, Otto Madelung presented 33 cases of benign symmetric lipomatosis and described the classic“horse collar”cervical distribution of the lipomatous tissue. Launois and Bensaude described benign symmetric lipomatosis as a distint syndrome characterized by a diffuse, symmetric, fatty accumulation in the cervical region. This disease is rare condition affecting mostly middle aged alcoholic men and associated with many systemic diseases such as diabetes mellitus, hyperuricemia, renal tubular acidosis, liver enzyme abnormality etc. The condition does not spontaneously involute and surgical excision is the only proven method of treatment, and recurrence is frequent. We experienced six patients of benign symmetric lipomatosis who underwent surgical excision via collar incision which afford wide exposure of the entire cervical area. We report them with the review of literature.