• Journal of Digital Convergence
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• v.20 no.4
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• pp.215-224
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• 2022

This study tried to examine the effect of cost asymmetry on food service companies and what characteristics affect such cost behavior. This study analyses cost behavior for cost of good sold, selling, general and administrative cost over the 2019-2020 period. Also, the rate of change in activity level was measured using change in sales. This study measures the behavior of cost using the research model of [1]. As a result of the analysis, it was found that food service companies exhibited cost asymmetric behavior as their sales level decreased. In addition, the cost asymmetric behavior has been strengthened since the corona virus, and the shorter the operating cycle. Lastly, the shorter the inventory holding period and the collection period of accounts receivable, which are components of the operating cycle, more strengthen asymmetric behavior of costs. These results seem to be meaningful in examining the cost structure and factors that may affect the structure for food service industry. This has approached the cost aspect of the situation faced by service food companies due to COVID-19, and it can be suggested that this pandemic can lead to cost reduction due to a decrease in corporate sales.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.13 no.3
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• pp.1611-1625
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• 2019

The emergence of new technologies and devices brings a new environment in the field of cyber security. It is not easy to predict possible security threats about new environment every time without special criteria. In other words, most malicious codes often reuse malicious code that has occurred in the past, such as bypassing detection from anti-virus or including additional functions. Therefore, we are predicting the security threats that can arise in a new environment based on the history of repeated malicious code. In this paper, we classify and define not only the internal information obtained from malicious code analysis but also the features that occur during infection and attack. We propose a method to predict and manage security threats in new environment by continuously managing and extending.

• Korean Journal of Head & Neck Oncology
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• v.23 no.1
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• pp.21-25
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• 2007

Background：Squamous cell carcinoma(SCC)of the palatine tonsils represents approximately 15-23% of all intraoral SCC. The most frequently reported risk factors for oropharyngeal cancer are smoking and alcohol. In a recent overview of HPV and tonsillar squamous cell carcinoma(TC), 51% contained HPV DNA, and HPV-16 being the most frequent type. We aimed to clarify whether HPV directly effects on the oncogenesis and biologic behavior of TC by comparison with infection prevalence, and physical status of virus. Material and Method：We used HPV genotyping DNA chip(Biocore, Korea, Seoul) arrayed by multiple oligonucleotide probes of L1 sequence of 26 types of HPV and HPV genotypes are identified by fluorescence scanner. The copy numbers of HPV E2 and E6 open reading frames(ORF) were assessed using a TaqMan-based 5'-exonuclease quantitative real-time PCR assay. The ratio of E2 to E6 copy numbers was calculated to determine the physical status of HPV-16 viral gene. Results：We observed a significant difference in HPV prevalence between 52 TCs and 69 CFTs(73.1% vs. 11.6%), and most of the HPVs were type 16(87.2%)and non-episomal(94.1%) state. Conclusions：This study regarding HPV infection prevalence and mechanism in the largest population of palatine tonsillar squamous cell carcinoma with chronic follicular tonsillitis revealed significant difference pf HPV prevalence between TC and CFT. Most of HPV were 16 type and integrated or mixed, HPV-16 integration could be directly related to tonsillar carcinogenesis.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.9
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• pp.3709-3713
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• 2015

Background: Many factors, including molecular ones, were demonstrated to be associated with long-term prognosis of hepatocellular carcinoma (HCC). Thus far, the expression and clinicopathologic and prognostic significance of the carboxyl terminus of Hsp70-interacting protein (CHIP) in B-type hepatitis virus (HBV)-related HCC remain unknown. Materials and Methods: CHIP expression was detected by immunohistochemical staining of surgical samples from 79 patients with HCC with HBsAg positivity. In addition, correlations with clinicopathologic parameters and patient survival were evaluated. Results: It was found that positive CHIP staining was observed in tumor, but not non-tumor, tissues. High expression of CHIP was significantly related to larger tumor size, with marginally significant associations noted for presence of portal vein invasion and higher serum a-fetoprotein level. In addition, univariate analysis showed that high CHIP expression was a powerful predictor for dismal overall and disease-free survival. However, independent prognostic implications of CHIP were not proven in multivariate Cox regression test. Conclusions: CHIP is overexpressed in HBV-related HCC and is associated with unfavorable biological behavior as well as poor prognosis. However, its prognostic role needs to be further validated.

• Proceedings of the Korean Information Science Society Conference
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• 2001.04a
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• pp.754-756
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• 2001

컴퓨터 사용증가와 함께 컴퓨터 바이러스 또한 증가하고 있다. 바이러스 검사 프로그램은 바이러스의 특정 문자열(signature)을 찾아 문자열 검색도구와 프로세스의 행동을 모니터링 하는 감시도구(general purpose monitor)의 두 가지 형태가 있으며, 각각은 미 발견 바이러스에 대한 취약성과 시스템 오버헤드를 단점으로 가지고 있다. 또한, 최근에 제안된 면역 시스템은 계산 복잡도나 시스템 구성면에서 지나친 부담을 가지고 있다. 본 논문에서는 바이러스들의 행위를 추출 할 수 있도록 하기 위하여, 언어 압축 알고리즘을 이용하여 바이러스 행동 패턴을 추출하는 방법을 고안하였고, 몇 가지 바이러스를 이용하여 실험해 보았다. 그 결과 실제 학습에 이용한 바이러스가 아니더라도 유사한 동작을 하는 바이러스에 대해서는 면역성을 가질 수 있었다.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.18
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• pp.7693-7702
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• 2014

Background: Human papilloma virus (HPV) occurs in women of all age groups, and causes cervical, anal, vaginal, vulvar, penile and oropharyngeal cancers. The aim of the study was to discover what nurses know about HPV infection, testing and vaccination and to determine vaccine practice of their daughters and perceived barriers. Materials and Methods: This cross-sectional and prospective study was carried out nurses who have worked in a hospital between January and June 2014. Pre-test and post-test were used to evaluate the nurses' knowledge about HPV infection, testing and vaccination. This study was performed with nurses who had girls between 9 and 26 years of age for evaluating the behavior of vaccination after three months of education. Results: The mean of pre-test and post-test scores about HPV infection, which included 22 items, were $8.2{\pm}5.6$ and $19.2{\pm}1.5$, respectively. Before education the HPV testing knowledge score was remarkably poor ($1.9{\pm}1.7$ over 5), after education it increased to $4.8{\pm}0.5$. The mean HPV vaccine knowledge score were $3.7{\pm}2.7$ (pre-test) $7.3{\pm}0.8$ (post-test) on a 0-8 scale. The difference between mean total pre-test ($13.9{\pm}9.1$) and post-test ($31.3{\pm}1.9$) scores was statistically significant (p<0.001). After three months of education, only two of the nurses' daughters were vaccinated. The main reason was noted by nurses were not willing to be vaccinated was cost, doubts about safety and efficacy related to the vaccine. About one-third of nurses declared that they would receive the vaccine for their daughter later. Conclusions: Nurses have a crucial role in the prevention, treatment, increasing public awareness and care for population. The education of the nurses about HPV infection, test and vaccination will play an important part decreasing cancer mortality and morbidity.

• Korean Journal of Bronchoesophagology
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• v.7 no.2
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• pp.152-160
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• 2001

The presence of HPV DNA and the expression of p53 protein and proliferating cell nuclear antigen(PCNA) in head and neck squamous cell carcinoma were determined to evaluate the relationship of these factors and their association with their pathologic stages and cervical lymph node metastasis. Among 65 patients the presence of HPV DNA was found in 12 cases(18.5%), p53 was found positive in 32 cases(49.2%) and expression of PCNA was observed in 24 cases(36.9%). The expression of PCNA was more frequent in the HPV positive cancers compared with the HPV negative ones(p =0.0018), and p53 revealed its higher rate of cooccurrence with the expression of PCNA(p =0.008), which might suggest that PCNA expression has a positive relationship with HPV and p53 mutation in head and neck cancer. There might be inverse relationship between HPV and p53 mutation(p =0.063), but 3 cases showed both HPV DNA positivity and p53 expression. HPV was detected at a higher rate in the early pathologic stages than in the advanced stages of cancer, and p53 expression was more frequently found in the advanced stages(p =0.044). These results suggests that HPV and p53 mutation might have different etiologic roles in the development of head and neck cancer, or cases with p53 mutation might have more aggressive behavior. PCNA expression showed no difference between early and late stages of cancer, and between cases with and without cervical lymph node metastasis.

• Journal of Digital Convergence
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• v.16 no.3
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• pp.311-319
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• 2018

This research attempted to identify the factors associated with the intention of human papilloma virus vaccination among mothers of elementary school daughters. The subject of study is 132 mothers of elementary school students. Data collection was conducted from July 1 to August 30 in 2017, and analyzed using SPSS 23.0 Program. Results showed that 94.7% children of the participants had not been vaccinated, whose reasons were the low knowledge about HPV vaccination, concerns about its side effects, burden for cost. The attitude toward HPV vaccination appeared to be the most important predictor of vaccination, which was followed by perceived behavior control and subjective norm as meaningful predictors, as well. Based on these results, further researches should be conducted to develop educational programs, which are able to offer exact information about the effect and side effect of HPV vaccination, and verify the effectiveness.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.31 no.1
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• pp.73-81
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• 2021

When downloading files using an app or web-based application on the user's mobile phone, the path is set to be saved in the pre-defined default directory. Many applications requiring access to storage, including file managers, require a write or read permission of storage to provide numerous functions and services. This means that the application will have direct access to the download folder where the numerous files downloaded. In this paper, to prove our feasibility of attack using the security vulnerabilities mentioned above, we developed a file hacking function disguised as an encryption function in the file management application. The file that encrypted will be sent to hackers via E-mail simultaneously on the background. The developed application was evaluated from VirusTotal, a malicious analysis engine, was not detected as a malicious application in all 74 engines. Finally, in this paper, we propose a defense technique and an algorithm based on the Trusted Execution Environment (TEE) to supplement these storage vulnerabilities.

• Journal of the Korean Society of School Health
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• v.9 no.2
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• pp.249-266
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• 1996

AIDS and the spectrum of Human Immunodeficiency Virus(HIV) infections present a monumental challenge to the health of the Korean public. In response to this special challenge, I think public education and voluntary behavior changes are the most effective measures to fight the spread of the disease. Adolescents represent a critical risk group for prevention and intervention programming. Research indicates sexually active adolescents, homosexual contact, illicit drug use are an gradually increasing. These characteristically adolescent risk-taking behaviors suggest the need for schools and communities to mobilize intervention strategies. Schools are highly efficient ways to reach a majority of young people in Korea with HIV prevention programs. These programs include substantial attention to sexual and drug use behaviors with the long term objective of a multidimensional school health program. Information resulting from risk behavior surveillance activities and guidance on school health curricula is particularly useful. What is needed for adolescents is a revamping of education to give students the critical thinking and analytic skills that allow them to apply knowledge, make decisions, and think independently. The best HIV preventive education provides young people with opportunities to learn and practice just those skills. In the early stages of HIV education were focused solely on information. Providing information is easy but unfortunately, behavior change is not that simple to activate. Information must be combined with values exploration and skilly building, including responsible decision making, negotiation, refusal, and critical thinking skills. The same knowledge, attitudes and skills needed for effective HIV prevention also prevent or reduce other risks, including other sexually transmitted diseases, unwanted pregnancies, and alcohol or other drug use. The role of other youth serving organizations in HIV prevention is also important: parental and youth involvement is needed; it's important to presidential and governament leadership is essential to prevention education; promote integrated adolescent programs, to enhance health and education sector collaboration; and of course, we need to expand research on adolescent health and engage the media in health promotion. Among these changes, a school-based systematic health education of AIDS is certainly one of the essentials.