• International Journal of Oral Biology
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• v.32 no.4
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• pp.119-125
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• 2007

Dlx3 is a homeodomain protein and is known to play a role in development and differentiation of many tissues. Deletion of four base pairs in DLX3 (NT3198) is causally related to tricho-dento-osseous (TDO) syndrome (OMIM #190320), a genetic disorder manifested by taurodontism, hair abnormalities, and increased bone density in the cranium. The molecular mechanisms that explain the phenotypic characteristics of TDO syndrome have not been clearly determined. In this study, we examined phenotypic characteristics of wild type DLX3(wtDlx3) and 4-BP DEL DLX3 (TDO mtDlx3) in C2C12 cells. To investigate how wtDlx3 and TDO mtDlx3 differentially regulate osteoblastic differentiation, reporter assays were performed by using luciferase reporters containing the promoters of alkaline phosphatase, bone sialoprotein or osteocalcin. Both wtDlx3 and TDO mtDlx3 enhanced significantly all the reporter activities but the effect of mtDlx3 was much weaker than that of wtDlx3. In spite of these differences in reporter activity, electrophoretic mobility shift assay showed that both wtDlx3 and TDO mtDlx3 formed similar amounts of DNA binding complexes with Dlx3 binding consensus sequence or with ALP promoter oligonucleotide bearing the Dlx3 binding core sequence. TDO mtDlx3 exhibits a longer half-life than wtDlx3 and it corresponds to PESTfind analysis result showing that potential PEST sequence was missed in carboxy terminal of TDO mtDlx3. In addition, co-immunoprecipitation demonstrated that TDO mtDlx3 binds to Msx2 more strongly than wtDlx3. Taken together, though TDO mtDlx3 acted as a weaker transcriptional activator than wtDlx3 in osteoblastic cells, there is possibility that during in vivo osteoblast differentiation TDO mtDlx3 may antagonize transcriptional repressor activity of Msx2 more effectively and for longer period than wtDlx3, resulting in enhancement of osteoblast differentiation.

• Journal of the Earthquake Engineering Society of Korea
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• v.12 no.3
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• pp.11-20
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• 2008

In this paper, the characteristics of low hardness high damping rubber bearings(HDRB) were studied through various prototype tests. The low hardness HDRB were tested to evaluate vertical stiffness, shear stiffness, equivalent damping ratio, various dependencies of shear properties, ultimate shear properties and other factors. The prototype test was performed according to the specifications of ISO 22762-1, and evaluated according to the specifications of ISO 22762-3. The results of the prototype test showed that shear strain and temperature were the factors that most greatly influenced shear stiffness, and that compressive stress was the factor that most greatly influenced the equivalent damping ratio. The frequency dependence test of shear properties showed that two general tendencies of frequency dependence could be observed. At frequencies over 0.1Hz, the changes in shear properties were small. However, at frequencies under 0.1Hz, the changes in shear properties rapidly decreased. The creep test and the ultimate shear test were also performed, and both of them satisfied the requirements of ISO 22762-3.

• Journal of the Mineralogical Society of Korea
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• v.6 no.1
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• pp.17-26
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• 1993

Mineralogical characteristics of tosudite from the Sungsan and Bubson mines were studied and correlated using X-ray diffraction analysis, chemical analysis and electron microscopy. Tosudite occurs as an alteration product of Cretaceous volcanoclastic rocks in both mines. It is associated with microcrystalline quartz, dickite, illite/smectite or mica/smectite mixed-layer mineral. It forms cryptocrystalline aggregates with flaky habit. XRD analysis suggests that tosudite is an 1:1regularly interstratified dioctahedral smetite/dioctahedral chlorite. Bubsoo tosudite has more(00ℓ ) reflections and more periodice stacking sequence than Syngsan tosudite. Chemical analysis shows that tosudite is a Li-bearing aluminous 1:1 regularly interstrattified mineral composed of K-bedellite and donbassite. Cookeite component may be present in the chlorite layer. Bubsoo tosudite is more Al in tetrahedral site and Ca in interlayer, but less Al in octahedral site than Sugsan tosudite. Tosudite may be formed as the intermediate alteration products, forming after muscovite and before illite/smectite or mica/s$^{\circ}C$mectite, with the range from 100 $^{\circ}C$ to 360 ~ 480 $^{\circ}C$. The hydrothermal solution forming tosudite may be acidic solution with high activities of Si and Al.

• Journal of Bio-Environment Control
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• v.19 no.3
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• pp.130-134
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• 2010

To investigate effects of deep tillage before planting on physicochemical properties of soil, growth and fruit characteristics in cultivation of watermelon (Citrullus vulgaris L. cv. 'Uriggul') under plastic film house, this study was conducted in cultivating field of Gochang Junbuk. pH in soil after harvest compared with soil before planting of watermelon had almost no change, but EC lowed greatly in the two treatments. Available phosphate concentration in the soil with the deep tillage treatment was lower, K concentration of exchangeable cation decreased greatly than these with conventional tillage treatment. In the growth at 27th day after planting plant, stem length to 10th node from the first node, leaf width with deep tillage treatment were longer, bearing node of the first and second flower and wilting degree were lower than these with conventional tillage treatment. In the growth of harvesting time, the stem length to 30th node from the first node with the deep tillage treatment were longer, leaf discoloration degree was lower than these with conventional tillage treatment. Also, the harvested fruits length, diameter, peel hardness, and weight were significantly better than these with conventional tillage treatment.

• Journal of Conservation Science
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• v.6 no.1 s.7
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• pp.31-60
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• 1997

Stone-cultural-properties, distributed in Naju, Hwasun and a part of Jangheung, have been investigated and studied on the characteristics, rock weathering and phases in the geological and conservational points of view. The properities involve pagoda and twelve stupas, four stone-buddha, three stone monuments, two stone-lantern, four stone-Jangseung, one and flag-pole. The rocks used are mainly pebble-bearing tuffaceous rocks of the Cretaceous age which are widely distributed in the area. However, granites are also used in some properties. These rocks are strongly influenced by weathering and pervasive moss. The mottled rock surfaces in some properties are in colors due to pervasive moss different. Parts of some cultural properties are broken which results in structurally unstable. Cultural properties in the area are relatively well conserved at the earth consolidated by ramming and by iron fence. However some cultural properties are partly repaired by using other hinds of rock phases which results in different colors in weathered rock surface. For conservation, rock phases, weathered surface colors, and relationships with original parts must be scientifically considered in repairment forward.

• Korean Journal of Breeding Science
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• v.42 no.5
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• pp.565-573
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• 2010

Thinning of apple fruitlets is one of the most laborious and important works for the improvement of fruit quality and for the promotion of sufficient flower bud formation to prevent alternate bearing in commercial cultivars. Lateral fruits of self-thinning apple cultivars fall naturally within 30 days after full bloom and only central fruit remains to mature. Differences of gene expression between central fruit and lateral fruit were investigated by differential display (DD) PCR. Partial cDNAs of 30 clones from the central fruit and 24 clones from the lateral fruit were selected for nucleotide sequence determination and homology searches. The levels of transcripts coding for proteins involved in pathogenesis related proteins, senescence, temperature stress, protein degradation, fruit browning, sorbitol metabolism were significantly higher in pedicels of lateral fruit than in pedicels of central fruit. On the other hand, the up-regulation of proteins involved in anthocyanin and flavanol biosynthesis and ethylene synthesis were observed in pedicels of central fruit. In Real time PCR analysis, cytochrome P450 gene was confirmed as showing a higher expression level in lateral fruit than in central fruit. The results of this study indicate that differentially expressed genes are related to self-thinning characteristics in apple tree.

• Wind and Structures
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• v.28 no.2
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• pp.71-87
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• 2019

The yaw and interference effects of blades affect aerodynamic performance of large wind turbine system significantly, thus influencing wind-induced response and stability performance of the tower-blade system. In this study, the 5MW wind turbine which was developed by Nanjing University of Aeronautics and Astronautics (NUAA) was chosen as the research object. Large eddy simulation on flow field and aerodynamics of its wind turbine system with different yaw angles($0^{\circ}$, $5^{\circ}$, $10^{\circ}$, $20^{\circ}$, $30^{\circ}$ and $45^{\circ}$) under the most unfavorable blade position was carried out. Results were compared with codes and measurement results at home and abroad, which verified validity of large eddy simulation. On this basis, effects of yaw angle on average wind pressure, fluctuating wind pressure, lift coefficient, resistance coefficient,streaming and wake characteristics on different interference zone of tower of wind turbine were analyzed. Next, the blade-cabin-tower-foundation integrated coupling model of the large wind turbine was constructed based on finite element method. Dynamic characteristics, wind-induced response and stability performance of the wind turbine structural system under different yaw angle were analyzed systematically. Research results demonstrate that with the increase of yaw angle, the maximum negative pressure and extreme negative pressure of the significant interference zone of the tower present a V-shaped variation trend, whereas the layer resistance coefficient increases gradually. By contrast, the maximum negative pressure, extreme negative pressure and layer resistance coefficient of the non-interference zone remain basically same. Effects of streaming and wake weaken gradually. When the yaw angle increases to $45^{\circ}$, aerodynamic force of the tower is close with that when there's no blade yaw and interference. As the height of significant interference zone increases, layer resistance coefficient decreases firstly and then increases under different yaw angles. Maximum means and mean square error (MSE) of radial displacement under different yaw angles all occur at circumferential $0^{\circ}$ and $180^{\circ}$ of the tower. The maximum bending moment at tower bottom is at circumferential $20^{\circ}$. When the yaw angle is $0^{\circ}$, the maximum downwind displacement responses of different blades are higher than 2.7 m. With the increase of yaw angle, MSEs of radial displacement at tower top, downwind displacement of blades, internal force at blade roots all decrease gradually, while the critical wind speed decreases firstly and then increases and finally decreases. The comprehensive analysis shows that the worst aerodynamic performance and wind-induced response of the wind turbine system are achieved when the yaw angle is $0^{\circ}$, whereas the worst stability performance and ultimate bearing capacity are achieved when the yaw angle is $45^{\circ}$.

• Economic and Environmental Geology
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• v.55 no.2
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• pp.197-207
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• 2022

This study investigated spectroscopic exploration of Myeonsan formation, the titanium(Ti) ore hostrock, in Joseon supergroup based on machine learning technique. The mineral composition, Ti concentration, spectral characteristics of Myeonsan and non-Myeonsan formation of Joseon supergroup were analyzed. The Myeonsan formation contains relatively larger quantity of opaque minerals along with quartz and clay minerals. The PXRF analysis revealed that the Ti concentration of Myeosan formation is at least 10 times larger than the other formations with bi-modal distribution. The bi-modal concentration is caused by high Ti concentrated sandy layer and relatively lower Ti concentrated muddy layer. The spectral characteristics of Myeonsan formation is manifested by Fe oxides at near infrared and clay minerals at shortwave infrared bands. The Ti exploration is expected to be more effective on detection of hostrock rather than Ti ore because ilmenite does not have characteristic spectral features. The random-forest machine learning classification detected the Myeonsan fomation at 85% accuracy with overall accuracy of 97%, where spectral features of iron oxides and clay minerals played an important role. It indicates that spectral analysis can detect the Ti host rock effectively, and can contribute for UAV based remote sensing for Ti exploration.

• Computers and Concrete
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• v.32 no.3
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• pp.247-261
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• 2023

Due to the non-uniform distribution of meso-structure, the diffusion of chloride ions in concrete show the characteristics of characteristics of randomness and fuzziness, which leads to the non-uniform distribution of chloride ions and the non-uniform corrosion of steel rebar in concrete. This phenomenon is supposed as the main reason causing the uncertainty of the bearing capacity deterioration of reinforced concrete structures. In order to analyze and predict the durability of reinforced concrete structures under chloride environment, the random features of chloride ions transport in concrete were studied in this research from in situ meso-structure of concrete. Based on X-ray CT technology, the spatial distribution of coarse aggregates and pores were recognized and extracted from a cylinder concrete specimen. In considering the influence of ITZ, the in situ mesostructure of concrete specimen was reconstructed to conduct a numerical simulation on the diffusion of chloride ions in concrete, which was verified through electronic microprobe technology. Then a stochastic study was performed to investigate the distribution of chloride ions concentration in space and time. The research indicates that the influence of coarse aggregate on chloride ions diffusion is the synthetic action of tortuosity and ITZ effect. The spatial distribution of coarse aggregates and pores is the main reason leading to the non-uniform distribution of chloride ions both in spatial and time scale. The chloride ions concentration under a certain time and the time under a certain concentration both satisfy the Lognormal distribution, which are accepted by Kolmogorov-Smirnov test and Chi-square test. This research provides an efficient method for obtain mass stochastic data from limited but representative samples, which lays a solid foundation for the investigation on the service properties of reinforced concrete structures.

• Korean Journal of Heritage: History & Science
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• v.56 no.4
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• pp.6-22
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• 2023

The National Museum of Korea's 'Shinchungmyeong Jochong' is the sole firearm in the country bearing inscriptions written in ink('辛丑改備江華庫藏'). Thanks to this written record, it is possible to determine where this firearm was stored and to make an estimate of the time when it was stored. Additionally, it is a valuable artifact that has been exceptionally well preserved and has an artistic design. However, research into the operational period, form, and structural characteristics of this firearm has been limited to date. This study aimed to shed light on the operational period, form, and structural features of the 'Shinchukmyeong Jochong.' To achieve this, the specifications and structural characteristics of the firearm were examined, and comparisons were made with 17 other extant firearms and their attributes. The results confirmed that the 'Shinchungmyeong Jochong' is a representative example of the typical firearms of the Joseon Dynasty. Next, the timing, background, and production subject of the Ganghwado containment of the Jochong were tracked based on letters found with the Jochong. The investigation revealed an entry in the 'Records of King Jeongjo'(『正祖實錄』) indicating that a significant amount of military supplies, including firearms, were stored on Ganghwado in December of the 5th year of Shinchung(1781). The decision to store these materials in Ganghwado Island may have been due to the perception of the Joseon decision-makers, who strategically valued Ganghwado Island, and the relocation of 'Tongaoyeong'(統禦營) and the integration with 'Jinmuyeong'(鎭撫營). After acquisition, it is presumed that the firearm was operated at locations like 'Jinmuyeong'(鎭撫營). The firearm's production is presumed to have been associated associated with institutions such as 'Gungisi'(軍器寺). In conclusion, the 'Shinchungmyeong Jochong' exemplifies a typical firearm of the Joseon Dynasty, and it is likely that it was stored on Ganghwado in December of 1781. Its production is believed to have been related to institutions such as 'Gungisi'. Following its acquisition, it is presumed that the firearm was operated at locations including 'Jinmuyeong'.