• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2012년도 추계학술대회 논문집
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• pp.691-692
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• 2012

• Clinical and Experimental Otorhinolaryngology
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• 제11권4호
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• pp.288-292
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• 2018

Objectives. To investigate the common causes of persistent septal deviation in revision septoplasty and to report the surgical techniques and results to correct them. Methods. A total of 100 consecutive patients (86 males) who had revision septoplasty due to persistent septal deviation from 2008 and 2014 were included in the study. Their mean age was 35.6 years and the mean follow-up duration was 9.1 months. Presenting symptoms, sites of persistent septal deviation, techniques used to correct the deviation, and surgical results were reviewed. Results. The mean interval between primary and revision surgery was 6.2 years. Forty-eight patients received revision septoplasty and 52 received revision septoplasty combined with rhinoplasty. Nasal obstruction was the most presenting symptom in almost all patients. The most common site of persistent septal deviation was middle septum (58%) followed by caudal septum (31%). Correcting techniques included further chondrotomy and excision of deviated portion in 76% and caudal batten graft in 39%. Rhinoscopic and endoscopic exams showed straight septum in 97% and 92 patients had subjective symptom improvement postoperatively. Conclusion. Middle septum and caudal septum were common sites of persistent deviation. Proper chondrotomy with excision of deviated middle septum and correction of the caudal deviation with batten graft are key maneuvers to treat persistent deviation.

• 한국전산유체공학회:학술대회논문집
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• 한국전산유체공학회 2006년도 PARALLEL CFD 2006
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• pp.63-65
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• 2006

• Wind and Structures
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• 제10권6호
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• pp.495-510
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• 2007

Wind pressure data have been collected on the tiled roof of a full-scale test house at Silsoe in the UK. The tiled roof was of conventional UK construction with a batten-space and bitumen-felt underlay beneath the interlocking concrete tiles. Pressures were monitored on the outer surface of selected tiles, at several locations within the batten-space, and beneath the underlay. Data were collected both with and without ventilator tiles installed on the roof. Little information appears to exist on the share of wind load between tiles and underlays which creates uncertainty in the design of both components. The present study has found that for the critical design case of maximum uplifts it would be appropriate to assign 85% of the net roof load to the tiles and 15% to the underlay when an internal pressure coefficient of -0.3 is used, and to assign 60% to the tiles and 50% to the underlay when an internal pressure coefficient of +0.2 is assumed (an element of design conservatism is inherent in the apparent 110% net loading indicated by the latter pair of percentage values). These findings indicate that compared with loads implied by BS 6399-2, UK design loads for underlay are currently conservative by 25% whilst tile loads are unconservative by around 20% in ridge and general regions and by around 45% in edge regions on average over roof slopes of $15^{\circ}-60^{\circ}$.

• 생명과학회지
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• 제19권4호
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• pp.520-525
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• 2009

영아형 바텐병은 PPT1 결핍 및 기능장애로 인해 발병하며, 12,500명 당 1명의 발병률을 가진 신경 퇴행 질환이다. 전 세계적으로 수많은 연구가 진행 중 이지만, 아직 명확하게 밝혀진 발병원인 및 치료방법에 대해서는 알려지고 있지 않다. 본 연구에서는 뇌에서 풍부하게 발현되는 neurogranin의 발현수준이 WT과 EBD KO 쥐에서 어떤 변화를 보이는지 확인하기 위해 mRNA, 단백질, 배양된 neurospheres를 이용하여 실험을 수행하였다. real-time PCR을 통한 neurogranin의 발현수준 비교 결과 WT에서는 노화와 무관하게neurogranin mRNA 수준에 차이가 없었으나, EBD KO 쥐에서는 노화가 진행됨에 따라 neurogranin mRNA 발현수준이 감소하였으며, 뇌에서 추출된 단백질을 이용한 western blot 분석에서도 real-time PCR과 동일한 결과를 확인할 수 있었다. 또한 WT, EBD KO 쥐의 태아로 부터 neural stem cell 인 neurospheres를 배양하여 western blot 분석을 수행한 결과 PPT1 결핍에 의해 neurogranin의 정상적인 인산화에 문제가 발생함을 확인하였다. 이러한 결과들을 바탕으로 neurospheres에 산화스트레스 유발물질인 $H_2O_2$를 처리하였고, 24시간 경과 후 항산화제인 NAC을 처리하자 $H_2O_2$를 처리한 시료에서는 mock control인 인산화된 neurogranin에 비해 그 수준이 증가하였으며, $H_2O_2$ 처리 후 NAC을 투여한 시료의 인산화 수준은 mock control 보다는 높았지만 $H_2O_2$만을 처리한 시료 수준보다 neurogranin의 인산화 정도가 감소하는 결과를 확인하였다. 이러한 결과들을 통해 PPT1 결핍으로 인해 신경세포 내에 과다하게 인산화된 neurogranin이 존재하며, neurogranin 인산화 정도는 세포가 지닌 산화스트레스 정도에 의해 변화함을 알 수 있었다. 또한 항산화제를 사용하여 세포의 산화스트레스 수준을 감소시킬 경우 neurogranin의 기능을 정상적으로 회복시킬 수 있는 가능성을 확인하였다.

• 대한지리학회지
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• 제46권2호
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• pp.181-196
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• 2011

본 연구의 목적은 최근의 경제 환경 변화 속에서 도시성장을 설명하는 새로운 모형으로 대두된 네트워크 도시를 심층적으로 이해하는 것이다. 이를 위하여 1990년대 중반 Batten(l995)의 시론적인 네트워크 도시 연구로부터 출발하여 현재에 이르기까지 관련 연구들을 정리하고 궁극적으로 네트워크 도시이론의 다양한 측면, 즉 형성과정, 공간구조, 관리 및 도시계획에의 응용, 성장에 대한 전망 등을 고찰해 봄으로써 네트워크 도시이론이 21세기의 도시현상을 설명하는데 적절한 이론인지에 대한 판단을 위해 필요한 포괄적인 지식을 제공하고자 한다. 관련연구들을 분석해본 결과 네트워크 도시는 경제의 세계화와 교통 및 정보통신기술의 발전과 함께 수반된 도시현상의 변화를 적절히 설명해 주는 이론일 뿐만 아니라 유럽을 중심으로 여러 도시정부들이 도시계획원리로 적극적으로 수용해 나가는 추세에 있는 유용한 개념으로 판단된다.

• Journal of Chest Surgery
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• 제51권6호
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• pp.390-394
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• 2018

Background: The nonsurgical treatment of chest wall deformity by a vacuum bell or external brace is gradual, with correction taking place over months. Monitoring the progress of nonsurgical treatment of chest wall deformity has relied on the ancient methods of measuring the depth of the excavatum and the protrusion of the carinatum. Patients, who are often adolescent, may become discouraged and abandon treatment. Methods: Optical scanning was utilized before and after the intervention to assess the effectiveness of treatment. The device measured the change in chest shape at each visit. In this pilot study, patients were included if they were willing to undergo scanning before and after treatment. Both surgical and nonsurgical treatment results were assessed. Results: Scanning was successful in 7 patients. Optical scanning allowed a visually clear, precise assessment of treatment, whether by operation, vacuum bell (for pectus excavatum), or external compression brace (for pectus carinatum). Millimeter-scale differences were identified and presented graphically to patients and families. Conclusion: Optical scanning with the digital subtraction of images obtained months apart allows a comparison of chest shape before and after treatment. For nonsurgical, gradual methods, this allows the patient to more easily appreciate progress. We speculate that this will increase adherence to these methods in adolescent patients.

• 한국근적외분광분석학회:학술대회논문집
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• 한국근적외분광분석학회 2001년도 NIR-2001
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• pp.1022-1022
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• 2001

To obtain accurate and repeatable analyses using NIR technology it is important to select an NIR instrument and / or its sample presentation attachments which allow the operator to minimize sampling errors without compromising the benefits of NIR analysis -namely rapid, low cost, minimal sample preparation, minimal structural facilities, minimal hazards. For each sample type and consistency there may be different optimal combinations of instrument, sample presentation attachment, and sample preparation. This paper will consider options available to NIR users in the area of plant and soil analysis and evaluate the potential benefits and disadvantages of crop nutrient diagnoses using laboratory based and airborne imaging techniques.

• Wind and Structures
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• 제4권1호
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• pp.73-84
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• 2001

Analysis of pressures measured on the roof of the full-scale Texas Tech building and a 1/50 scale model of a typical house showed that the pressure fluctuations on cladding fastener and cladding-truss connection tributary areas have similar characteristics. The probability density functions of pressure fluctuations on these areas are negatively skewed from Gaussian, with pressure peak factors less than -5.5. The fluctuating pressure energy is mostly contained at full-scale frequencies of up to about 0.6 Hz. Pressure coefficients, $C_p$ and local pressure factors, $K_l$ given in the Australian wind load standard AS1170.2 are generally satisfactory, except for some small cladding fastener tributary areas near the edges.

• KIEAE Journal
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• 제10권3호
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• pp.17-26
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• 2010

This study aims at exploring the characteristics of the Usonian houses of Frank Lloyd Wright from an ecological viewpoint. After considering the definition and application of ecological architecture through literature review, 28 Usonian houses were selected and analyzed for the study. Also, nine Usonian houses, which clearly have ecological and historical importance, were visited and more thoroughly analyzed. The result shows that Usonian houses are ecological in terms of 1) the relationship among nature, landscape and house, 2) the orientation, natural light and natural ventilation, 3) the use of natural local materials including wood, stones and bricks, 4) the use of floor heating (the On-dol system inKorea), 5) the human scale, 6) the use of the board and batten unit (an early system of prefabrication), and 7) the openness and flexibility of floor plans.