• International Journal of Contents
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• 제5권2호
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• pp.6-15
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• 2009

Recently many different programming languages have emerged for the development of bioinformatics applications. In addition to the traditional languages, languages from open source projects such as BioPerl, BioPython, and BioJava have become popular because they provide special tools for biological data processing and are easy to use. However, it is not well-studied which of these programming languages will be most suitable for a given bioinformatics task and which factors should be considered in choosing a language for a project. Like many other application projects, bioinformatics projects also require various types of tasks. Accordingly, it will be a challenge to characterize all the aspects of a project in order to choose a language. However, most projects require some common and primitive tasks such as file I/O, text processing, and basic computation for counting, translation, statistics, etc. This paper presents the benchmarking results of six popular languages, Perl, BioPerl, Python, BioPython, Java, and BioJava, for several common and simple bioinformatics tasks. The experimental results of each language are compared through quantitative evaluation metrics such as execution time, memory usage, and size of the source code. Other qualitative factors, including writeability, readability, portability, scalability, and maintainability, that affect the success of a project are also discussed. The results of this research can be useful for developers in choosing an appropriate language for the development of bioinformatics applications.

• 대한간호학회지
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• 제31권5호
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• pp.793-806
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• 2001

To identify nursing interventions performed by Chosunjok nurses in Yanbian using NIC. Methods: The sample consisted of 36 nurses working in 2 hospitals. The Nursing Interventions Use Questionnaire developed by the Iowa Intervention Project team was used for data collection. The instrument was translated to Korean using the method of back-translation. Results: Twenty-eight interventions were performed at least daily. Interventions in the Physiological: Basic domain were most frequently used at least daily. The most frequently used interventions was Positioning, followed by the interventions Pressure Ulcer Prevention, Intravenous (IV) Therapy, Hypothermia Treatment and Intravenous (IV) Insertion. The least frequently used interventions was Electronic Fetal Monitoring: Antepartum. Nurses working in special medical care units performed interventions most often, while nurses working in general surgical units performed them least. Nurses working in general medical, special medical and other care units performed interventions in the Physiological domain more often than the nurses working in general surgical units. Conclusion: Chosunjok nurses in Yanbian performed physiological interventions frequently. Further studies will be needed to compare interventions performed by nurses in two countries.

• 한국공작기계학회:학술대회논문집
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• 한국공작기계학회 2004년도 추계학술대회 논문집
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• pp.382-387
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• 2004

As the increasing needs in the industrial filed, many studies for the 3D CAD system are carried out. There are two types of 3D CAD system. One is manifold modeler, the other is non-manifold modeler. In the manifold modeler only 3D objects can be modeled. In the non-manifold modeler 3D, 2D, 1D, and 0D objects can be modeled in a unified data structure. Recently there are many studies on the non-manifold modeler. Most of them are focused on finding unknown topological entities and representing all kinds of topological entities found. In this paper, efficient data structure is selected. The boundary information on a face and an edge is included in this data structure. The boundary information on a vertex is excluded considering the frequency of usage. Because the disk cycle information is not required in most case of modeling. It is compact. It stores essential non-manifold information such as loop cycle and radial cycle. A suitable Euler-Poincare equation is studied and selected. Using the efficient data structure and the selected Euler-Poincare equation, 18 basic Euler operators are implemented. Several 3D models are created using the implemented modeler. A non-manifold modeling can be carried out using the implemented 3D CAD system. The results of this paper could be used in the further studies such as an implementation of Boolean operators, and a translation of 2D CAD drawings to 3D models.

• 한국의사학회지
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• 제14권2호
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• pp.59-82
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• 2001

The book, "Euibangyoochui醫方類聚"(A.D. 1445) is called the treasure-house of the knowledge of medical science, due to the 50,000 prescriptions and an enormous amount of medical information that it contains. But in spite of the importance of this book, a convenient and efficient method to use the information in this book isn't developed yet and as a result the use of this book in a low state. Therefore before than anything else, there is necessity to establish the database on "Euibangyoochui". Before the establishment of database on "Euibangyoochui", there are basic works that should be preceded as follows; like the correction through investigating and comparing between the texts that are related with "Euibangyoochui", interpretation, proofread and translation to Korean of the original. And also bibliographical research on "Euibangyoochui". The compilatory course and transmissional system of the medical books in first term of Chosun(朝鮮) was able to apprehend through the bibliographical research about "Euibangyoochui". Also, many emergency medical books and books about the prevention of the infectious diseases mostly based on "Euibangyoochui" were wrote and put to practical use. And this fact, tells us that the compilation of "Euibangyoochui" was supported by the government of Chosun as means to accumulate the medical knowledge.

• 대한수의학회지
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• 제52권2호
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• pp.99-104
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• 2012

The present study was performed to evaluate the relationship between the neurotoxicity of acrylamide and the differential gene expression pattern in mice. Both locomotor test and rota-rod test showed that the group treated with higher than 30 mg/kg/day of acrylamide caused impaired motor activity in mice. Based on cDNA microarray analysis of mouse brain, myelin basic protein gene, kinesin family member 5B gene, and fibroblast growth factor (FGF) 1 and its receptor genes were down-regulated by acrylamide. The genes are known to be essential for neurofilament synthesis, axonal transport, and neuroprotection, respectively. Interestingly, both FGF 1 and its receptor genes were down-regulated. Genes involved in nucleic acid binding such as AU RNA binding protein/enoyl-coA hydratase, translation initiation factor (TIF) 2 alpha kinase 4, activating transcription factor 2, and U2AF 1 related sequence 1 genes were down-regulated. More interesting finding was that genes of both catalytic and regulatory subunit of protein phosphatases which are important for signal transduction pathways were down-regulated. Here, we propose that acrylamide induces neurotoxicity by regulation of genes associated with neurofilament synthesis, axonal transport, neuro-protection, and signal transduction pathways.

• 제어로봇시스템학회논문지
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• 제22권8호
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• pp.579-584
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• 2016

When surgical instruments are tracked in an image-guided surgical navigation system, a stereo vision system with high accuracy is generally used, which is called optical tracker. However, this optical tracker has the disadvantage that a line-of-sight between the tracker and surgical instrument must be maintained. Therefore, to complement the disadvantage of optical tracking systems, an internal vision sensor is attached to a surgical instrument in this paper. Monitoring the target marker pattern attached on patient with this vision sensor, this surgical instrument is possible to be tracked even when the line-of-sight of the optical tracker is occluded. To verify the system's effectiveness, a series of basic experiments is carried out. Lastly, an integration experiment is conducted. The experimental results show that rotational error is bounded to max $1.32^{\circ}$ and mean $0.35^{\circ}$, and translation error is in max 1.72mm and mean 0.58mm. Finally, it is confirmed that the proposed tool tracking method using an internal vision sensor is useful and effective to overcome the occlusion problem of the optical tracker.

• Journal of Plant Biology
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• 제32권1호
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• pp.51-65
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• 1989

Glycinin is the major storage protein in soybean. It has been known that a molecule of glycinin is composed of 6 subunits, each of which consists of two different kinds of polypeptides, acidic (A) and basic (B) one (NW 39K and 19K, respectively). To study the molecular origin and the relationship of glycinin subunit polypeptides, antibodies against A-and B-polypeptide were obtained by immunizing rabbits with either of the antigens purified by gel filtration and preparative electrophoresis. Each antibody was not only specific for its own antigen polypeptide in soybeans but also recoginzed the precursor which was synthesized in vivo and in vitro. The polyadenylated mRNAs were isolated from immature seeds and leaves and were translated in vitro using wheat germ extract. One of the seed-specific translation products. MW 60K, was identified to be the precursor of glycinin subunit by immunoprecipitation with antibodies against glycinin A- and B-polypeptide. Mature A- and B-polypeptides were not detected in the translte in vitro. These results suggest that the precursor polypeptide is synthesized from the mRNA and is cleaved to yield A- and B-polypeptides which from a glycinin subunit in the cell. Glycinin genes were expressed with the maturation of soybean seeds in a tissue-specific and developmental stage-specific manner.

• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 1999년도 추계종합학술대회
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• pp.454-457
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• 1999

해양분야의 정보들은 대부분 지리정보와 관련되어 있으며 또한 응용 분야 및 시스템에 따라 표현 방식이 상이하여 시스템 차원의 개발 비용이 증가하고 있다 이러한 문제를 해결하기 위한 근본적인 방법은 해양정보에 대한 단일 개념의 데이터 모델을 기반으로 한 자료 이용체계를 확립하는 것이다. 본 논문에서는 해양정보의 GIS 기반 객체 데이터 모델 정의를 위한 가이드라인을 설정하고 이에 따른 객체 데이터 모델을 설계한다. 이러한 GIS 기반 객체 데이터모델을 설계하여 데이터베이스 시스템을 구축함으로서 데이터 통합, 관리 및 응용시스템 개발 전반에 관한 효율성 증진을 예상할 수 있을 것이다.

• 한국조경학회지
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• 제23권2호
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• pp.223-241
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• 1995

Ji Cheng's great work on garden design, the 'Yuanye'(Craft of garden), written in 1631 and originally published in 1634 is the first surviving manual on landscape gardening in the Chinese tradition. This study aims at investigating not only Ji Cheng's life, achievements companionship and design activities, but also the xylographic copies, literary style, and framework of Yuanye in their historical context in order to provide the bases for further study, Ji Cheng was exellent in poetry and painting. And he constructed Dongdiyuan in Changzhou around 1623, Wuyuan in Yiaheng in 1631, and Yingyuan in Yangzhou around 1634 But no poems, paintings, and gardens designed by hi shill exist Therefore his design phi philosophy is able to be interpreted only by his work, Yuanye. After publishing, Yuanye fell into obscurity for several centuries in Chlna. It was redescovered and reprinted for the first time in 1931. Yuanye is composed of prefaces and main text The main text is divided into 'the Theory of Construction' and 'on Gardens', and the latter also into 10 sections. In this text Ji Cheng explains the aesthetic principles underlying garden design and the appropriate emotional response to various efftcts Especially, he emphasizes the importance of basin the garden design on the taxi ting nature and features of landscape and making use of natural scenery. The literary style of the book is highly mannered, and there are so many poetic descriptions and Ji Cheng's native Jiangsu dialects. So the translation of the original text is very difficult After this, the major design concepts of Ji Cheng's landscape gardening theory and whole network of these concepts have to be studied.

• 정보학연구
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• 제8권3호
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• pp.1-10
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• 2005

Cosine and Sine function is widely used for the arithmetic, translation, object drawing, Simulation and etc. of Computer Graphics in Natural Science and Engineering. In general, Cordic Algorithm is effective method since it has relatively small size and simple architecture on trigonometric function generation. However profitably it has those merits, the problem of operation speed is occurred. In graphic display system, the operation result of object drawing is quantized and has the condition that is satisfied with rms error less than 1. So in this paper, the proposed generator is composed of partition operation at each ${\pi}/4$ and basic Cosine, Sine function generator in the range of $0{\sim}{\pi}/4$ using the lower order of Tayler's series in an acceptable error range, that enlarge the range of $0{\sim}2{\pi}$ according to a definition of the trigonometric function for the purpose of having a high speed Cosine, Sine function generation. And, division operator using code partition for divisor three is proposed, the proposed function generator has high speed operation, but it has the problems in the other application parts with accurate results, is need to increase the speed of the multiplication.