• 약학회지
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• 제41권3호
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• pp.283-293
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• 1997

Some analogs and their Mannich bases of Antineoplaston A10 (A10) were synthesized. Chemical yield for the 2-(or 3-)thienyl, benzol, and phenylpropionyl analogs were high but 1-naphthyl analog was synthesized in low yield. The Mannich bases formation of these analogs with morpholine went verywell compared to other bases. 1-Naphthyl, 4-nitrobenzoyl, and phenylpropionyl analogs of A10 showed weak in vitro activity but the other A10 analogs showed weaker or no activity at 10-1000mcg/ml. But their Mannich bases containing A10analogs showed good in vitro activity compared to simple A10 analogs.

• Bulletin of the Korean Chemical Society
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• 제26권4호
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• pp.548-552
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• 2005

The interaction between ionic surfactants and different nonionic molecules and polymers are studied using ion surfactant selective electrode. From the experimental data, critical concentrations of the interaction and binding process are evaluated. The interaction between hexadecyltrimethylammonium bromide (HTAB) with polyethylene glycol (PEG) in three molecular weights (1000, 10000 and 100000) and also schiff-bases, 2-[2-carboxyphenyl nitrilomethylidyne]-phenol (ortho CNP), 2-[3-carboxyphenyl nitrilomethylidyne]-phenol (meta CNP)and 2-[4-carboxyphenyl nitrilomethylidyne]-phenol (para CNP) with the potentiometric method were investigated using HTAB membrane selective electrode. In the case of PEG with increasing molecular weights more interaction to HTAB occurs. The electromotive force (EMF) data also showed that interaction between para CNP with HTAB is more than the other schiff-bases. It seems this case related to less space interference of COOH group for that compound. The onset of binding ($T_1$) of course is the same for three schiffbase molecules.

• 건축역사연구
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• 제9권2호
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• pp.49-63
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• 2000

In this research, we analyzed the activities of Japanese architectural offices in Korea during the Japanese occupation era, classifying them into two groups: first, Japanese architectural offices that had their bases in Korea, and second, Japanese architectural offices that had their bases in Japan. There were totally 98 Japanese architectural offices that had their bases in Korea during the Japanese occupation period. The number of those offices had increased rapidly since 1920s. Nakamura(the design of bank buildings), Tamada(the design of theaters), Otsumi(the design of Japanese style residential houses) can be regarded as the most remarkable Japanese architectural offices among them. We found that these offices already specialized in certain architectural planning fields, such as bank buildings, theaters and residential houses. It was also found that, during the Pacific War period, even privately-managed architectural offices were mobilized for the war by Japanese government, through designing munitions factories, etc. On the one hand, since some large Japanese corporations entered into Korea, many Japanese architectural offices, that had their bases in Japan, got into working in Korea and designed a number of buildings, with the exception of the architectural office of Vories, who was a Christian architect. Even though the place that the activities of these Japanese architectural offices were carried out was Korea, any factors of Korean architectural style couldn't be found In their works. This means that they just transplanted the Japanese modern architectural style in Korea.

• 한국전자통신학회논문지
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• 제10권3호
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• pp.387-393
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• 2015

유한체위에서 ECC를 기반으로 하는 전자상거래 또는 비밀통신에서 송수신자가 서로 다른 기저를 사용하는 경우에는 기저변환으로 인한 통신지연이 발생하게 된다. 본 논문에서는 서로 다른 기저를 사용하는 H/W와 S/W 구현 시스템 사이의 비밀통신 또는 전자서명에 소요되는 기저변환의 횟수를 분석하여, 그로 인한 통신지연을 제거하기 위해서, All One Polynomial(AOP)을 사용하는 유한체위에서 하드웨어와 소프트웨어 구현 모두에 효과적이면서, 기저변환이 필요 없는 근점 기저를 소개하였다. 제안하는 근점기저를 사용한 곱셈기의 H/W 구현 결과, 삼항식과 다항식기저를 사용하는 곱셈기보다 연산 시간이 약 25% 감소하였다.

• The Journal of Advanced Prosthodontics
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• 제9권5호
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• pp.402-408
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• 2017

PURPOSE. The goal of this study was to compare the adhesion of Candida albicans to the surfaces of CAD/CAM and conventionally fabricated complete denture bases. MATERIALS AND METHODS. Twenty discs of acrylic resin poly (methyl methacrylate) were fabricated with CAD/CAM and conventional procedures (heat-polymerized acrylic resin). The specimens were divided into two groups: 10 discs were fabricated using the CAD/CAM procedure (Wieland Digital Denture Ivoclar Vivadent), and 10 discs were fabricated using a conventional flasking and pressure-pack technique. Candida colonization was performed on all the specimens using four Candida albicans isolates. The difference in Candida albicans adhesion on the discs was evaluated. The number of adherent yeast cells was calculated by the colony-forming units (CFU) and by Fluorescence microscopy. RESULTS. There was a significant difference in the adhesion of Candida albicans to the complete denture bases created with CAD/CAM and the adhesion to those created with the conventional procedure. The CAD/CAM denture bases exhibited less adhesion of Candida albicans than did the denture bases created with the conventional procedure (P<.05). CONCLUSION. The CAD/CAM procedure for fabricating complete dentures showed promising potential for reducing the adherence of Candida to the denture base surface. Clinical Implications. Complete dentures made with the CAD/CAM procedure might decrease the incidence of denture stomatitis compared with conventional dentures.

• 한국연초학회지
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• 제27권2호
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• pp.207-211
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• 2005

This study was carried out to develop calibration equation of total volatile bases of tobacco leaf using near infrared spectroscopy(NIRS). Burley, imported flue-cured and oriental leaf tobacco samples were collected in 2005 crop year. Calibration equation was developed by modified partial least square method. The standard error of calibration and $R^2$ between traditional analytical method and NIRS analytical method were $0.038\%$, 0.983 for burley and $0.027\%$, 0.986 for imported flue-cured and oriental leaf, respectively. The standard error of performance and $R^2$ between traditional analytical method and NIRS analytical method were $0.048\%$, 0.940 for burley and $0.024\%$, 0.986 for imported flue-cured and oriental leaf, respectively. From these results, the NIRS analytical method seems to be applicable in analyzing total volatile bases of tobacco.

• Earthquakes and Structures
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• 제1권3호
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• pp.231-252
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• 2010

Previous research on pounding between seismically isolated buildings during earthquakes has been focused on impacts at the bases of structures and the effect of simultaneous interactions at the bases and at the superstructures has not been studied in details. In this paper, the seismic responses of adjacent buildings supported on different or similar base systems considering impacts between bases and superstructures are numerically investigated. The study is carried out in three parts for the two types of adjacent buildings: (i) both structures have fixed bases; (ii) one structure has fixed base and the other is seismically isolated and (iii) both structures have base isolation systems. The results of the study indicate that the pounding-involved responses of the buildings depend mainly on the type of structural base systems and on the structural parameters of both buildings. For the base-isolated building, the variation of the peak accelerations and displacements of the storeys have been found to be relatively low. On the other hand, significant differences have been observed for the fixed base building. The results of the parametric study conducted for different values of the gap size between colliding structures show the reduction in the peak base displacements as the gap distance decreases.

• 디지털융복합연구
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• 제14권6호
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• pp.61-67
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• 2016

본 연구는 BIM기반의 U-안전모니터링에 대한 연구가 주된 내용이다. 연구절차는 다음과 같다. 첫째, 연구의 배경 및 필요성과 연구의 목적 및 연구범위, 방법을 제시하였다. 둘째, BIM의 개념을 설명하고 BIM기반의 U-안전모니터링의 선행되어야 할 고려사항이나 조건 등을 조사하였다. 셋째, 수치지도 사업현황파악 및 BIM 기반 U-안전모니터링구축의 필요요건, BIM과 연동되는 U-안전모니터링시스템이 보다 공간을 확장한 지역영속성계획인 DCP의 적용성에 대하여 조사하였다. 넷째, 연구결과를 토대로 미래 U-안전모니터링을 제시하였다. 마지막으로 결론부분에는 DCP기반의 U-안전모니터링의 발전방향에 논하였다.

• Bulletin of the Korean Chemical Society
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• 제32권1호
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• pp.71-76
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• 2011

An efficient nucleophilic [$^{18}F$]fluorination has been studied to reduce byproducts and preparation time. Instead of conventional aqueous solution of $K_2CO_3-K_{222}$, several organic solution containing inert organic salts were used to release [$^{18}F$]fluoride ion and anion bases captured in the polymer cartridge, concluding that methanol solution is the best choice. Comparing to azeotropic drying process, one min was sufficient to remove methanol completely, resulting in about 10% radioactivity saving by reducing drying time. The polymer cartridge, Chromafix$^{(R)}$ (PS-$HCO_3$) was pretreated with several anion bases to displace pre-loaded bicarbonate base. Phosphate bases showed better results than carbonate bases in terms of lower basicity. tert-Butanol solvent used as a reaction media played another critical role in nucleophilic [18F]fluorination by suppressing eliminated side product. Consequent [$^{18}F$]fluorination under the present condition afforded fast preparation of reaction solution and high radiochemical yields (98% radio-TLC, 84% RCY) with 94% of precursor remained.

• Bulletin of the Korean Chemical Society
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• 제24권7호
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• pp.943-947
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• 2003

We have studied the migration behavior of single-stranded DNA using capillary gel electrophoresis under various conditions. It was found that optimum electric fields should be less than 150 V/cm for the good tradeoff between the separation time and the resolution. It seems that the gel matrix with the combination of different polymer average molecular weights is important to extend the maximum readable DNA bases. The total gel concentration less than 3.1% in the mixed gel system showed good separation efficiency up to 600 bases. The best result was obtained with the poy(ethylene)oxide (PEO) gel concentration of 1.2% of Mr 8,000,000 and 1.8% of Mr 600,000. We observed that the capillary length between 50 cm to 100 cm (effective length) should be employed for the optimization between the total DNA migration time and the maximum readable length. A trizma base-boric acid-ethlyenediaminetetraacetic acid (EDTA) (TBE) buffer was commonly used for DNA sequencing, but we found that 3-[tris(hydroxymethyl)methyl amino]-1-propane sulfonic acid (TAPS) buffer worked as well for the single-stranded DNA separation. Especially, TAPS buffer showed a good resolution for very short DNA bases (1 to 30 bases).