• Title/Summary/Keyword: baseline model

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Circulating folate levels and colorectal adenoma: a case-control study and a meta-analysis

  • Park, Yeong Mi;Youn, Jiyoung;Cho, Chang Ho;Kim, Sung Hi;Lee, Jung Eun
    • Nutrition Research and Practice
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    • v.11 no.5
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    • pp.419-429
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    • 2017
  • BACKGROUND/OBJECTIVES: The relationship between folate and colorectal neoplasia remains controversial. We examined the association between serum folate concentrations and colorectal adenomas in a case-control study of Korean adults and conducted a meta-analysis. SUBJECTS/METHODS: Our case-control study included 113 pairs of case and control who underwent colonoscopy and provided blood samples. We used multivariable conditional logistic regression models to obtain the odds ratios and 95% confidence interval (CIs). For meta-analysis, we identified the relevant studies by searching the PubMed database up to February 2017, included our case-control study and combined the study-specific relative risks (RRs) using a random-effects model. RESULTS: In this case-control study, we included 58 men and 55 women with colorectal adenomas and sex and fasting status matched the controls. We did not find any significant association between the serum folate levels and colorectal adenomas in either men or women. For meta-analysis, a total of eleven studies were included in our analysis and classified into two groups; polyp clearance group (PC) for the studies that included participants who underwent endoscopies and had their polyps removed at baseline; and no polyp clearance group (NPC) for the studies that included participants whose histories of endoscopies were unknown or who underwent their first endoscopies. Four PC (1,311 cases and 1,672 non-cases) and eight NPC studies (3,501 cases and 11,347 non-cases) were included. The combined RRs (95% CIs) comparing the bottom with the top categories of circulating folate levels were 1.07 (0.97-1.18) for the NPC group but 1.45 (1.16-1.74) for the PC group. CONCLUSIONS: Low circulating folate levels were associated with new adenoma formation.

Evidence-based customized nutritional intervention improves body composition and nutritional factors for highly-adherent children and adolescents with moderate to severe obesity

  • Kim, Jieun;Kim, YoonMyung;Seo, Young-Gyun;Park, Kyung-Hee;Jang, Han Byul;Lee, Hye-Ja;Park, Sang Ick;Lim, Hyunjung
    • Nutrition Research and Practice
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    • v.14 no.3
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    • pp.262-275
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    • 2020
  • BACKGROUND/OBJECTIVES: Evidence-based customized nutritional interventions are required for effective treatment of moderate to severe obese children and adolescents. SUBJECTS/METHODS: Sixty six (64.1% of 103) of the eligible participants who joined the usual care or physical activity group in the clinic were involved in 16-week intervention. Customized nutritional intervention was implemented for each participant based on a nutrition care process (NCP) model. Sociodemographic assessment, anthropometrics data, health- and dietary-related behaviors, and dietary intake of the study subjects were assessed at baseline and follow-up. All participants engaged in 30-minute nutritional sessions on a monthly basis. RESULTS: After 16 weeks, there were significant improvements in body composition [BMI (-0.8 ± 0.9, P < 0.05), BMI z-score (-0.3 ± 0.2, P < 0.001), body fat (kg) (-1.3 ± 2.1, P < 0.05), and body fat (%)(-1.5 ± 1.9, P < 0.05)] as well as macronutrient intake [total energy intake (kcal) (-563.7 ± 656.8, P < 0.05), energy (%) (-26.5 ± 30.0, P < 0.05) and fat (g) (-28.3 ± 40.6, P < 0.05)] in the adherent group than the non-adherent group. The SOC was higher in both groups after the intervention (P < 0.001). CONCLUSIONS: Our results highlight the positive effects of an evidence-based approach as a multidisciplinary intervention for people-centered nutritional care and weight management.

Analysis of Structural Relation between the Shipyard Workers' Ego-state, Safe and Unsafe Behaviors, and Industrial Accidents (조선업 작업자의 자아상태, 안전 및 불안전행동, 산업재해 간의 구조관계 분석)

  • Jeong, Inseok;Jeong, Daekyum
    • Journal of the Korean Society of Safety
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    • v.33 no.5
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    • pp.101-108
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    • 2018
  • This study was carried out to obtain baseline data on the causes of industrial accidents and their prevention by investigating structural models between the Shipyard workers' egogram ego-states (CP: Critical Parent, NP: Nurturing Parent, A: Adult, FC: Free Child, AC: Adapted Child), safe and unsafe behaviors, and industrial accidents (frequency/severity). In order to achieve this goal, 378 workers from 3 locations of major corporations in Geojedo Island and Ulsan took a questionnaire, which was then analyzed with a structural equation model using the SPSS 23.0 and AMOS 24 statistics package, and the main results of the study are as follows. First, NP and A's ego-states had a positive influence on safe behavior, AC's ego-state had a negative influence on safe behavior, and A's ego-state had the largest influence on safe behavior. Second, CP and AC's ego-states had a positive influence on unsafe behavior, and A's ego-state had a negative influence on unsafe behavior. AC's ego-state had the largest influence on unsafe behavior. Third, safe behavior did not have a significant influence on industrial accidents. However, unsafe behavior had a positive influence on industrial accident frequency and industrial accident severity, both sub-factors of industrial accidents. This study, despite its limitations, such as sampling limitations, has the following significance. First, this study verified that ego-state, a psychological characteristic, is an important factor for predicting unsafe behavior that induces industrial accidents. Second, in order to reduce industrial accidents, there is a need to stimulate the A ego-states, and promote continuous safety management and safety education to neutralize the AC ego-state. Third, previous studies were limited in the area of practical methods for reducing unsafe behaviors, but this study presents practical methods for reducing unsafe behaviors by verifying the structural relationship between safe/unsafe behaviors and industrial accidents by selecting ego-gram ego-states, variable personality theory, as an independent variable.

Assessment of Streamflow and Evapotranspiration Influence on the Climate Change under SRES A1B Scenario (기후변화에 따른 A1B 시나리오의 유출 및 증발산량 영향 평가)

  • Ahn, So-Ra;Park, Min-Ji;Park, Geun-Ae;Kim, Seong-Joon
    • Proceedings of the Korea Water Resources Association Conference
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    • 2008.05a
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    • pp.1097-1101
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    • 2008
  • 본 연구에서는 SLURP 수문모형을 이용하여 미래기후와 예측된 토지이용자료 및 식생의 활력도를 고려한 상태에서 하천유역의 유출 및 증발산량에 미치는 영향을 분석하였다. 경안천 상류유역($260.04\;km^2$)을 대상유역으로 선정하여 4개년(1999-2002) 동안의 일별 유출량 자료를 바탕으로 모형의 보정(1999-2000)과 검증(2001-2002)을 실시하였다. 모형의 보정 및 검정 결과 Nash-Sutcliffe 모형효율은 0.79에서 060의 범위로 나타났다. 미래 기후자료는 IPCC(Intergovernmental Panel on Climate Change)에서 제공하는 A1B 기후변화시나리오의 MIROC3.2 hires, ECHAM5-OM, HadCM3 모델의 결과값을 이용하였다. 먼저 과거 30년 기후자료(1977-2006, baseline)를 바탕으로 각 모델별 20C3M(20th Century Climate Coupled Model)의 모의 결과값을 이용하여 강수와 온도를 보정한 뒤 Change Factor Method로 Downscaling하였다. 미래 기후자료는 2020s(2010-2039), 2050s(2040-2069), 2080s(2070-2099)의 세 기간으로 나누어 분석하였다. 미래 토지이용은 과거 시계열 Landsat 토지이용도를 이용하여 CA-Markov기법으로 예측된 토지이용을 사용하였으며, 미래의 식생정보 예측을 위하여 NOAA/AVHRR 위성영상으로부터 추출된 월별 NDVI(1998-2002)와 월평균기온간의 선형 회귀식을 도출하여 미래의 식생지수 정보를 추정하였다. 모형의 적용결과, 미래기후변화에 따른 연평균 하천유출은 현재보다 최대 2020s는 23.9%, 2050s는 40.7%, 2080s는 39.5% 증가하였다. 봄 강수량 패턴의 변화로 유출량 증가하는 것으로 나타났으며 여름에는 유출량은 감소하고 증발산량은 증가하는 결과를 보였다.

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Monitoring Differences in Vaginal Hemodynamic and Temperature Response for Sexual Arousal by Different Anesthetic Agents Using an O ptical Probe

  • Jeong, Hyeryun;Seong, Myeongsu;Park, Kwangsung;Kim, Jae Gwan
    • Current Optics and Photonics
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    • v.4 no.1
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    • pp.57-62
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    • 2020
  • The selection of anesthetic agent is important in preclinical studies, since each agent affects the systemic hemodynamics in different ways. For that reason, we hypothesized that different anesthetic agents will result in different vaginal hemodynamic response and temperature during sexual arousal, in an animal model. To validate the hypothesis, animal experiments were performed using female rats with two anesthetic agents widely used in preclinical studies: ketamine and isoflurane. Our previously developed near-infrared-spectroscopy-based probe was used to measure the changes of oxyhemoglobin (OHb), deoxyhemoglobin (RHb), and total hemoglobin (THb) concentrations along with temperature from the animal vaginal wall. As a control, saline was administered to both isoflurane- and ketamine-anesthetized animals, and did not show any significant changes in OHb, RHb, THb, or temperature. However, an administration of apomorphine (APO, 80 ㎍/kg) induced increases of OHb (63 ± 28 μM/DPF), RHb (35 ± 20 μM/DPF), and THb (98 ± 49 μM/DPF) in ketamine-anesthetized animals, while decreases of OHb (52 ± 76 μM/DPF) and THb (38 ± 30 μM/DPF) and an increase of RHb (28 ± 51 μM/DPF) were found in isoflurane-anesthetized animals. The vaginal temperature decreased from the baseline in both ketamine-(0.42℃) and isoflurane-(1.22℃)anesthetized animals. These results confirmed our hypothesis, and suggest that a preclinical study monitoring hemodynamic responses under anesthesia should employ an appropriate anesthetic agent for the study.

Comparison of Standardized Peristomal Skin Care and Crusting Technique in Prevention of Peristomal Skin Problems in Ostomy Patients

  • Park, Seung-Mi;Lee, Yun-Jin;Oh, Doo-Nam;Kim, Ji-Yun
    • Journal of Korean Academy of Nursing
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    • v.41 no.6
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    • pp.814-820
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    • 2011
  • Purpose: This study was performed to compare the effects of standardized peristomal skin care (SPSC) and crusting technique (CT) on the peristomal skin of ostomates. SPSC was developed by a consensus among the expert group based on a comprehensive review of the relevant literature and hospital protocols. Methods: A randomized controlled pilot trial with 2 parallel arms was used. A total of 81 ostomates, who were recruited from a tertiary hospital, completed the baseline, 1-month, 2-month, and 3-month follow-up (SPSC group, n=45; CT group, n=36). SPSC consisted of water cleansing and direct application of ostomy appliances. CT involved crusting hydrocolloid powder and patting with water sponge or protective barrier liquid film. The outcomes of the study were assessed by skin problems, such as discoloration, erosion and tissue overgrowth; the domains of the evaluation tool used in examining the peristomal skin. A generalized estimating equation model was used to examine the effects according to time and group. Results: In both SPSC and CT groups, the likelihood of occurrence of discoloration (OR, 1.99; 95% CI, 1.61-2.46), erosion (OR, 1.87; 95% CI, 1.55-2.25) and tissue enlargement (OR, 1.94; 95% CI, 1.36-2.77) increased with time. There was no significant difference in discoloration between the groups, whereas the probability of erosion (OR, 0.38; 95% CI, 0.16-0.89) and tissue overgrowth (OR, 0.09; 95% CI, 0.02-0.55) was lower in the SPSC group than in CT group. Conclusion: SPSC was sufficient in preventing peristomal skin problems of ostomates compared to the CT.

Analysis of Relationship between Functional Areas and Individual Competencies of Extension Workers (농촌지도사의 직무영역과 개별역량의 관계분석)

  • Kim, Hyo Mi;Kim, Ji Hyun;Kim, Sa Gyun;Kim, Yoon Doo
    • Journal of Agricultural Extension & Community Development
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    • v.20 no.2
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    • pp.383-405
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    • 2013
  • The purpose of this study is trying to drive the competence relevant to extension worker's functions. We also conducted a correspondence analysis between the individual competence and extension worker's functions. As a result of the analysis, the functions of guidance planning correlated with 'problem solving' and 'creation of ideas'. Education functions correlated with 'extension work evaluation', 'customer satisfaction' and 'understanding'. And crop technology diffusion functions were analyzed relevant to the ability of 'training skill' and 'responsibility' is high. In this study, extension empowerment need to educate suitable education which is high relation between competency and extension worker's functions and develop new suitable education model. And the baseline data will be made use, when arrange reasonable function to new extension workers, through individual competency measured.

A Study on the Heat Transfer Performance of an Energy-Nose Section in a Household Refrigerator-Freezer (가정용 냉장고의 에너지 노즈부 열전달 특성에 관한 연구)

  • Lee, Moo-Yeon;Lee, Dong-Yeon;Kim, Yong-Chan
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.31 no.6 s.261
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    • pp.574-580
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    • 2007
  • The objective of this article is to present an analysis of all heat transfer paths through the energy nose under closed door conditions when refrigeration system of household refrigerator-freezer is operating on. Both experimental and numerical methods are suggested as a means of determining the overall energy nose load amount as well as the load due to each pathway such as mullion section and F and R sides of the household refrigerator-freezer. In other words, all loads determined in this article are just energy nose and not the loads seen by the refrigeration system. We suggest good ideas for improving the heat transfer losses such as conduction and convection through the energy nose. As we can be known from the experimental test results, it is effective to prevent the heat loss of a mullion section. And energy efficiency is also decreased approximately 6% compared to that of a baseline sample test result. As we can be known from the Ansys 8.1 analysis, it is shown the steady state temperature distribution in figures from 6 to 8. And the direction of the heat flow through the energy nose section is also easily seen from that In conclusion, the article is focused on an energy nose section in household refrigerator-freezer for practical proposes which is the energy saving in a household refrigerator-freezer. And the method suggested may be applied to any make or model to aid in the search for high efficient energy nose section of household side by side refrigerator-freezer as well as top mounted refrigerator-freezer, commercial refrigerator and so on.

Risk Factors related to Delirium Development in Patients in Surgical Intensive Care Unit (외과계 중환자실의 섬망 발생 위험요인 조사연구)

  • Lee, Eun-Joon;Shim, Mi-Young;Song, Suk-Hee;Lee, Mi-Mi;Kim, Hye-Mi;Kang, Bong-Sun;Yang, Eun-Jeen;Lim, Ji-Young;Kim, Jin-A;Lee, Mi-Na
    • Journal of Korean Critical Care Nursing
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    • v.3 no.2
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    • pp.37-48
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    • 2010
  • Purpose: The purpose of this study was to examine the frequency and the course of delirium, and identify risk factors for the development of delirium in surgical intensive care unit (SICU). Methods: Subjects older than 19 years admitted to the SICU were recruited. After informed written consent, enrolled subjects had baseline cognitive and functional assessments. Subjects were assessed daily for delirium using the Confusion Assessment Method-ICU (CAM-ICU). Results: During the study period, 110 patients were enrolled. The overall incidence of delirium was 20% (22/110). The average time to onset of delirium was 3.04(${\pm}1.25$) days. Several variables were associated with an increased risk of delirium including older age (p<.05), higher admission APACHE II score (p<.001), use of opioid and analgesics (p<.01), using physical restraints (p<.001), and intraoperative hypotension (p<.05). In a multivariate logistic regression model, using physical restraints (p<.001), intraoperative hypotension (p<.05), and older age (p<.05) remained significant predictors of the delirium development. Conclusion: Using physical restraints, intraoperative hypotension and older age was strongly associated with development of delirium in the SICU. Prevention measures need to focus on identifying patients at higher risk for delirium development.

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Computational aspects of guided wave based damage localization algorithms in flat anisotropic structures

  • Moll, Jochen;Torres-Arredondo, Miguel Angel;Fritzen, Claus-Peter
    • Smart Structures and Systems
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    • v.10 no.3
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    • pp.229-251
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    • 2012
  • Guided waves have shown a great potential for structural health monitoring (SHM) applications. In contrast to traditional non-destructive testing (NDT) methodologies, a key element of SHM approaches is the high process of automation. The monitoring system should decide autonomously whether the host structure is intact or not. A basic requirement for the realization of such a system is that the sensors are permanently installed on the host structure. Thus, baseline measurements become available that can be used for diagnostic purposes, i.e., damage detection, localization, etc. This paper contributes to guided wave-based inspection in anisotropic materials for SHM purposes. Therefore, computational strategies are described for both, the solution of the complex equations for wave propagation analysis in composite materials based on exact elasticity theory and the popular global matrix method, as well as the underlying equations of two active damage localization algorithms for anisotropic structures. The result of the global matrix method is an angular and frequency dependent wave velocity characteristic that is used subsequently in the localization procedures. Numerical simulations and experimental investigations through time-delay measurements are carried out in order to validate the proposed theoretical model. An exemplary case study including the calculation of dispersion curves and damage localization is conducted on an exemplary unidirectional composite structure where the ultrasonic signals processed in the localization step are simulated with the spectral element method. The proposed study demonstrates the capabilities of the proposed algorithms for accurate damage localization in anisotropic structures.