• Title/Summary/Keyword: base-excess

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A comparison of the Effects of Intravenous Fluid Warming and Skin Surface Warming on Peri-operative Body Temperature and Acid Base Balance of Elderly Patients with Abdominal Surgery (수액가온요법과 피부가온요법이 개복술 환자의 저체온 예방에 미치는 효과 비교)

  • Park, Hyo-Sun;Yoon, Hae-Sang
    • Journal of Korean Academy of Nursing
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    • v.37 no.7
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    • pp.1061-1072
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    • 2007
  • Purpose: The purpose of this study was to compare the effects of intravenous fluid warming and skin surface warming on peri-operative body temperature and acid base balance of abdominal surgical patients under general anesthesia. Method: Data collection was performed from January 4th, to May 31, 2004. The intravenous fluid warming(IFW) group(30 elderly patients) was warmed through an IV line by an Animec set to $37^{\circ}C$. The skin surface warming(SSW) group(30 elderly patients) was warmed by a circulating-water blanket set to $38^{\circ}C$ under the back and a 60W heating lamp 40 cm above the chest. The warming continued from induction of general anesthesia to two hours after completion of surgery. Collected data was analyzed using Repeated Measures ANOVA, and Bonferroni methods. Results: SSW was more effective than IFW in preventing hypothermia(p= .043), preventing a decrease of $HCO_3{^-}$(p= .000) and preventing base excess(p= .000) respectively. However, there was no difference in pH between the SSW and IFW(p= .401) groups. Conclusion: We conclude that skin surface warming is more effective in preventing hypothermia, and $HCO_3{^-}$ and base excess during general anesthesia, and returning to normal body temperature after surgery than intravenous fluid warming; however, skin surface warming wasn't able to sustain a normal body temperature in elderly patients undergoing abdominal surgery under general anesthesia.

Performance-based framework for soil-structure systems using simplified rocking foundation models

  • Smith-Pardo, J. Paul
    • Structural Engineering and Mechanics
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    • v.40 no.6
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    • pp.763-782
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    • 2011
  • Results from nonlinear time-history analyses of wall-frame structural models indicate that the condition of vulnerable foundations -for which uplifting and reaching the bearing capacity of the supporting soil can occur before yielding at the base of the shear walls- may not be necessarily detrimental to the drift response of buildings under strong ground motions. Analyses also show that a soil-foundation system can inherently have deformation capacity well in excess of the demand and thus act as a source of energy dissipation that protects the structural integrity of the shear walls.

A Study on the Development of CAD System for VFD Element Tools (형광 표시관 부품의 금형 자동설계 시스템에 관한 연구)

  • 박상봉
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 1997.04a
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    • pp.724-728
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    • 1997
  • A CAD system of grid element for vacuum fluorescent disply has been developed. In order to reduce design man-houre and human erros, it is used to automate the design process using a knowledge base system. In the case of VFD product design, the most important consideration is the short-life cycle. So the development of CAD system for VFD product is needed. The developed system is based on the knowledge base system which is involved in a lot of expert's technology in the practice field. Using C-language under the HP-UNIX system, CIS customer language of the EXCESS CAD/CAM is used as the overall CAD environment. Results of this system will provide effective aids to the designer in this field

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Staged Finite Element Modeling with Coupled Seepage and Stress Analysis

  • Lee, Jae-Young
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.23 no.6
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    • pp.703-714
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    • 2010
  • This paper proposes an approach for staged finite element modeling with coupled seepage and stress analysis. The stage modeling is based on the predefined inter-relationship between the base model and the unit stage models. A unit stage constitutes a complete finite element model, of which the geometries and attributes are subject to changes from stage to stage. The seepage analysis precedes the mechanical stress analysis at every stage. Division of the wet and dry zone and the pore pressures are evaluated from the seepage analysis and used in determining input data for the stress analysis. The results of the stress analysis may also be associated with the pore water pressures. For consolidation analysis, the pore pressure and the displacement variables are mixed in a coupled matrix equation. The time marching solution produces the dissipation of excess pore pressure and variation of stresses with passage of time. For undrained analysis, the excess pore pressures are computed from the stress increment due to loading applied in the unit stage and are used in revising the hydraulic head. The solution results of a unit stage are inherited and accumulated to the subsequent stages through the relationship of the base model and the individual unit stages. Implementation of the proposed approach is outlined on the basis of the core procedures, and numerical examples are presented for demonstration of its application.

Delta Neutrophil Index as an Early Marker of Sepsis in Burn Patients (화상환자에서 패혈증의 조기 예측인자로서의 DNI)

  • Kim, Chong Myung;Ha, Chul Min
    • Journal of the Korean Burn Society
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    • v.22 no.2
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    • pp.38-44
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    • 2019
  • Purpose: The immature granulocyte count has been reported to be a marker of infection and sepsis. The difference in leukocyte subfractions (delta neutrophil index, DNI) in ADVIA 2120 reflects the fraction of circulating immature granulocytes in the blood. This study evaluated the clinical utility of DNI as a severity and prediction marker in critically ill patients with burn sepsis. Methods: One hundred and sixty nine patients admitted to the burn care unit were studied. DNI (the difference in leukocyte subfractions identified by myeloperoxidase and nuclear lobularity channels) was determined using a specific blood cell analyzer. Results: Seventy one patients (42 %) were diagnosed with burn sepsis. DNI was significantly higher in patients with burn sepsis than in patients without (P<0.01). Delta neutrophil index was a better indicator of burn sepsis than C-reactive protein, lactate, white blood cell count, HCO3, base excess, lactate, procalcitonin (odds ratio, 6.31; confidence interval 2.36~16.90; P<0.01). And the receiver operating characteristic curves showed that delta neutrophil index, AUC 0.795 (95% confidence interval, 0.721~0.869; P<0.05) was a better predictor of burn sepsis than lactate, procalcitonin, white blood cell, base excess and abbreviated burn severity index. Conclusion: Delta neutrophil index may be used as a early marker of patients with burn sepsis.

Preparation of (S)-(+)-Pranidipine by Optical Resolution (광학 분할에 의한 (S)-(+)-Pranidipine의 제조방법)

  • Baek, Du-Jong;Yoon, Ji Hye;Kim, Moon-Sik
    • Journal of the Korean Chemical Society
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    • v.59 no.6
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    • pp.488-492
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    • 2015
  • In this study, the effective preparation method of (S)-(+)-pranidipine, the active component of antihypertensive drug as a calcium channel blocker, was developed using optical resolution. The racemic monocarboxylic acid 5 obtained by the hydrolysis of (±)-pranidipine was mixed with optically active quinidine to form salts, and the insoluble diastereomeric salt was collected and successive treatment with base and acid furnished (R)-(-)-carboxylic acid 7. (S)-(+)-Pranidipine was prepared by esterification of this acid with cinnamyl alcohol, and the analysis by chiral HPLC showed 100% enantiomeric excess (ee). This process would be industrially very useful to prepare chiral (S)-(+)-pranidipine, since the use of strong base and anhydrous solvents, and ultra-low temperature condition were excluded in this process.

A Study on Development of Insert Metal for Liquid Phase Diffusion Bonding of Fe Base Heat Resistance Alloy (Fe 기내열합금의 액상확상접합용 삽입금속의 개발에 관한 연구)

  • 강정윤;김인배;이상래
    • Journal of Welding and Joining
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    • v.13 no.3
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    • pp.147-156
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    • 1995
  • The change of microstructure in the bonded interlayer and tensile properties of joints were studied for liquid phase diffusion bonding using STS-310 and Incoloy-825 as base metal and base metal+B alloy as insert inetal. Main experimental results obtained in this study are as follows. 1) The optimum amount of B addition into the insert metal was found to be about 4mass%. 2) When isothermal solidification was completed, the microstructure in the bonded interlayer was the same with that of the base metal because of the grain boundary migration in the bonded interlayer. 3) All of the tensile specimen fractured at base metal and joints bonded at optimum condition exhibited tensile properties in excess of base metal requirements. 4) It was determined that fine car-borides and bordes such as M$_{23}$(C,B)$_{6}$, Cr$_{2}$B, and CrB in STS-310S and TiB in Incoloy-825 exist at the grain boundary around bonded interlayer. These precipitates almost disappeared after homogenizing treatment at 1373K for 86.4ks.s.

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Effect of Excess CuO on the Sintering Behavior and Piezoelectric Properties of Bi0.5(Na0.82K0.18)0.5TiO3 Ceramics (Bi0.5(Na0.82K0.18)0.5TiO3 세라믹스의 소결거동 및 압전 특성에 대한 과잉의 CuO 첨가 효과)

  • Kang, Jin-Kyu;Jang, Hyun-Deok;Heo, Dae-Jun;Lee, Hyun-Young;Ahn, Kyoung-Kwan;Lee, Jae-Shin
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.27 no.6
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    • pp.372-376
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    • 2014
  • We investigated the effect of excess CuO on the sintering behavior, ferroelectric, and piezoelectric properties of lead-free $Bi_{0.5}(Na_{0.82}K_{0.18})_{0.5}TiO_3$ (BNKT) ceramics. The addition of excess CuO was found to greatly contribute to the densification and grain growth, however, excess CuO over 3 mol% was precipitated at grain boundaries after sintering. BNKT with 1~2 mol% CuO in excess sintered at $975^{\circ}C$ showed piezoelectric properties comparable to those of unmodified BNKT sintered at $1,175^{\circ}C$. These results seem meaningful for its application to low cost multilayer actuators (MLAs) because low firing ceramics make it possible to apply less expensive base metals to the inner electrode of MLAs.

An Expert System of the Very Thin Sheet Metal Press Die Automated Design for VFD Grid (진공형광소자 전극의 극박판 프레스 금형 자동설계 전문가 시스템)

  • 박상봉
    • Journal of the Korean Society for Precision Engineering
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    • v.15 no.5
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    • pp.50-58
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    • 1998
  • A proper model of expert system for the very thin sheet metal press die design has been suggested. Using the suggested model, an expert system of the very thin sheet metal press die has been developed. This study contains that the results from the developed system for three kinds of specimens have the adaptability in the actual site. In addition, the possibility for expansion of this system has been discussed. The developed system, which is based on the knowledge base, has been included in a lot of expert's technology in the practice field. C-language under the HP-UNIX system and CIS customer language of the EXCESS CAD/CAM system have been used as the overall CAD environment. Results from this system will provide effective aids to the designer in this field.

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Effects of Long-term Heat Exposure on Adaptive Mechanism of Blood Acid-base in Buffalo Calves

  • Korde, J.P.;Singh, G.;Varshney, V.P.;Shukla, D.C.
    • Asian-Australasian Journal of Animal Sciences
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    • v.20 no.5
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    • pp.742-747
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    • 2007
  • In order to investigate the mechanism of adaptation to long-term heat stress, six female buffalo calves of about 7 to 8 months age, were exposed to the cool-comfort environment (THI 65) for 21 days to obtain normal values of blood acid-base. An adaptive response of acid-base regulation was determined to long term (21 days) exposure of buffalo calves to hot-dry (THI 80) and hot-humid (THI 84) conditions. Higher rectal temperature and respiratory rate was recorded under hot-humid exposure compared to hot-dry. Significant reduction in the rectal temperature and respiratory rate on day 21 of hot-dry exposure indicated early thermal adaptation compared to hot-humid. Decreasing rectal temperature and respiratory rate from day 1 to 21 was associated with concurrent decrease in blood pH and pCO2. Increased plasma chloride concentration with low base excess in blood and in extracellular fluid suggested compensatory response to respiratory alkalosis. Reduced fractional excretion of sodium with increased fractional excretion of potassium and urine flow rate indicated renal adaptive response to heat stress.