• The Korean Journal of Physiology and Pharmacology
• /
• 제17권1호
• /
• pp.43-50
• /
• 2013

Palmitic acid (PAM), one of the most common saturated fatty acid (SFA) in animals and plants, has been shown to induce apoptosis in exocrine pancreatic AR42J cells. In this study, we investigated cellular mechanisms underlying protective effects of oleic acid (OLA) against the lipotoxic actions of PAM in AR42J cells. Exposure of cells to long-chain SFA induced apoptotic cell death determined by MTT cell viability assay and Hoechst staining. Co-treatment of OLA with PAM markedly protected cells against PAM-induced apoptosis. OLA significantly attenuated the PAM-induced increase in the levels of pro-apoptotic Bak protein, cleaved forms of apoptotic proteins (caspase-3, PARP). On the contrary, OLA restored the decreased levels of anti-apoptotic Bcl-2 family proteins (Bcl-2, Bcl-xL, and Mcl-1) in PAM-treated cells. OLA also induced up-regulation of the mRNA expression of Dgat2 and Cpt1 genes which are involved in triacylglycerol (TAG) synthesis and mitochondrial ${\beta}$-oxidation, respectively. Intracellular TAG accumulation was increased by OLA supplementation in accordance with enhanced expression of Dgat2 gene. These results indicate that restoration of anti-apoptotic/pro-apop-totic protein balance from apoptosis toward cell survival is involved in the cytoprotective effects of OLA against PAM-induced apoptosis in pancreatic AR42J cells. In addition, OLA-induced increase in TAG accumulation and up-regulation of Dgat2 and Cpt1 gene expressions may be possibly associated in part with the ability of OLA to protect cells from deleterious actions of PAM.

• 대한물리의학회지
• /
• 제15권2호
• /
• pp.83-91
• /
• 2020

PURPOSE: Postural and structural asymmetry due to muscle imbalances around the lower back and pelvis are the causes of back pain. Muscle imbalances in patients with chronic low back pain affect the pelvic tilt and movement, and it is necessary to assess the pelvic movement ability using the appropriate tools to determine the mediating effects of lower back pain. This paper reports the reliability and validity of the Sensbalance Therapy Cushion (STC) for pelvic movement and proprioception. METHODS: In this study, the Wii balance board (WBB) was used as a golden standard for pelvic movement measurements. FABQ, KODI, Myovision, and Pelvic movement were measured in 50 patients with chronic low back pain. The correlation between the lower-back muscle activity and pelvic movement was checked. The pelvic movement parameter was measured twice to determine the intra-rater reliability. RESULTS: The STC showed high test-retest reliability in the pelvic tilt measurements (ICC = .672 - .809). The test-retest reliability of proprioception measurements (ICC = .588 - .859) and reaction time measurements (ICC = .542 - .836) were also high. The relationship between the WBB and STC showed a significant positive correlation with the pelvic tilt test (p < .01). The posterior pelvic tilt and lower-back muscle activity showed a significant negative correlation (p < .01). The pelvic left tilt and lower-back muscle activity showed a significant negative correlation (p < .05). CONCLUSION: The results revealed the high reliability and validity of the STC. Therefore, the STC can be used as an objective measuring device for evaluating pelvic tilt, proprioception, and reaction time in low back pain patients.

• Journal of Ecology and Environment
• /
• 제33권2호
• /
• pp.165-173
• /
• 2010

Soil respiration ($R_S$) is a critical component of the annual carbon balance of forests, but few studies thus far have attempted to evaluate empirical regression models in $R_S$. The principal objectives of this study were to evaluate the relationship between $R_S$ rates and soil temperature (ST) and soil water content (SWC) in soil from a cool-temperate deciduous broad-leaved forest, and to evaluate empirical regression models for the prediction of $R_S$ using ST and SWC. We have been measuring $R_S$, using an open-flow gas-exchange system with an infrared gas analyzer during the snowfree season from 1999 to 2001 at the Takayama Forest, Japan. To evaluate the empirical regression models used for the prediction of $R_S$, we compared a simple exponential regression (flux = $ae^{bt}$Eq. [1]) and two polynomial multiple-regression models (flux = $ae^{bt}{\times}({\theta}{\nu}-c){\times}(d-{\theta}{\nu})^f:$ Eq. [2] and flux = $ae^{bt}{\times}(1-(1-({\theta}{\nu}/c))^2)$: Eq. [3]) that included two variables (ST: t and SWC: ${\theta}{\nu}$) and that utilized hourly data for $R_S$. In general, daily mean $R_S$ rates were positively well-correlated with ST, but no significant correlations were observed with any significant frequency between the ST and $R_S$ rates on periods of a day based on the hourly $R_S$ data. Eq. (2) has many more site-specific parameters than Eq. (3) and resulted in some significant underestimation. The empirical regression, Eq. (3) was best explained by temporal variations, as it provided a more unbiased fit to the data compared to Eq. (2). The Eq. (3) (ST $\times$ SWC function) also increased the predictive ability as compared to Eq. (1) (only ST exponential function), increasing the $R^2$ from 0.71 to 0.78.

• 교육녹색환경연구
• /
• 제16권3호
• /
• pp.51-60
• /
• 2017

21세기 일본의 학교안전은 학교교육 정책의 변화에 따라 직접적인 영향을 받았다. 일본 학교교육의 목적은 "살아가는 힘(zest for life)"을 증진시킴으로써 자립 협동 창조적인 인간으로 육성하는데 있다. 이를 반영하여 학교안전의 목적도 어떠한 재난 상황에서도 학생 스스로 극복할 수 있는 생존 역량을 강화하는데 두고 있다. 일본 학교안전의 주요특징은 다음과 같다: 1) 스스로 살아남을 수 있는 역량 강조 2) 가정 및 지역사회의 학교안전 역할 중시 3) 학교안전과 학교교육의 균형 4) 체험학습 및 능동적 학습(active learning)을 통한 안전교육 강조 5) 안전한 학교시설 추구 6) 학교안전 개선을 위한 PDCA(Plan-Do-Check-Act) 적용 7) UN 안전학교 모델 도입 및 확산. 일본 학교안전에 대한 논의는 최근 제도적 변화가 급격히 이루어지고 있는 우리 나라 학교안전에 의미 있는 시사를 줄 것이다.

• The Journal of Korean Physical Therapy
• /
• 제25권2호
• /
• pp.88-95
• /
• 2013

Purpose: The purpose of this study was to conduct an analysis of kinematics of lower extremities and trunk in stance phase of walking according to turning direction. Methods: Ten university students (five male, five female) who were in their 20s (mean age was 20.6 years old) participated in this study. Participants did not have participants did not have any problem with skeletal muscular system. We used the "Qualisys motion capture system" for analysis of trunk and lower extremity movement in stance phase of walking according to turning direction. We collected data while subjects walked a distance of 10 m, and at the 6 m line, subjects were required to turn to the left side and the right leg was positioned in stance phase and the left leg was positioned in swing. For data analysis, the SPSS for Windows ver. 20.0 statistics program was used in performance of one way analysis of variance according to turning direction. Results: Significant difference of trunk and lower extremities was observed for turning direction according to walking cycle (p<0.05). Upper trunk movement showed a greater increase at three dimensions than lower trunk, and in heel off phase, pelvic movement showed a greater increase than lower trunk (p<0.05). In 45 degree and 90 degrees of turning direction, all movements of trunk and lower extremities were significantly different among three events of stance phase (p<0.05). Conclusion: We suggest that three-dimensional movement analysis of trunk and lower extremities during turning movement was very important in order to indicate increasing balance or walking ability for people with impaired movement or walking.

• PNF and Movement
• /
• 제15권2호
• /
• pp.167-176
• /
• 2017

Purpose: This study investigated the effect of core and abdominal muscle-strengthening exercises on muscle activity in the lower extremity on unexpected perturbation. Methods: Twenty subjects were randomly divided into the core exercise group (n=10) or the abdominal muscles strengthening group (n=10). The two groups performed their exercises during three sessions a week for a total of four weeks. The muscle activity in the lower muscles (rectus femoris, biceps femoris, tibialis anterior, gastrocnemius) was assessed using surface electromyography (EMG) and normalized maximal voluntary isometric contraction (MVIC) before and after the exercises. Results: An increase in the tibialis anterior activity after the core and abdominal muscles strengthening exercises was found after four weeks. A significant difference in the pre- and post-exercise was found. The gastrocnemius muscle activity increased in the core exercise group more than the abdominal muscles strengthening group. However, the difference was not significant. Conclusion: The results of this study suggest that the core and abdominal muscles strengthening exercises increased the tibialis anterior muscle activity. It is expected to help make more balance ability that affect who has abdominal muscles weakness.

• 대한수학교육학회지:수학교육학연구
• /
• 제12권1호
• /
• pp.145-162
• /
• 2002

In this study, on the basis of the seventh national mathematics curriculum, the achievement standards were developed to specify the objectives and contents of teaching-learning and the assessment standards were also developed to differentiate students' levels of achievement at school mathematics. The achievement standards were developed on the following guidelines; 1) to present the minimum standards based on the national curriculum, 2) to develop the standards based on the order of curriculum, 3) to suggest the minimum but ultimate achievement target, 4) to comprise not only of the intellectual but also of psychological spheres such as knowledge, function, attitude, aptitude, etc., and 5) to suggest the standards comprehensively and concretely. The standards were developed on the basis of the middle areas of contents of the curriculum in order not to be too comprehensive, nor to be too detailed. Learning activities, on the other hand, were provided for the assistance of instructions with emphasis on creativity rather than on the routine instruction. The assessment standards were established based on the following principles; 1) to establish the assessment methods, contents, and situations which are to be used for assessment, 2) to establish the criteria of classifying the assessed into the upper, intermediate and lower levels, 3) to develop the assessment standards in a proportionate balance to achievement standards, 4) to establish the intermediate level as a standard, and 5) to establish the minimum level in the contents, concepts, values and attitudes of basic learning. This study also suggested the exemplary test items including short-answer and open-ended questions while putting emphasis on students' real performance to increase their ability in solving problems rather than in calculating. In addition to the test items, it introduced the grading system developed to grade the items with concrete guidelines and to report students' achievement on doing mathematics.

• 대한물리의학회지
• /
• 제13권1호
• /
• pp.137-146
• /
• 2018

PURPOSE: This study examine the effect of community ambulation training on gait, depression and self - efficacy of stroke patients in order to develop more effective training methods of community rehabilitation. METHODS: In the experimental group, community ambulation training combined with indoor and outdoor walking was performed for 30 minutes three times a week for six weeks. In the control group, general indoor walking training was performed. The physical factors were assessed by a 10-meter walking test, six-minute walking test and community gait test. Psychological factors were assessed by the Korean version of the Epidemiology Center Depression Scale and Activity-Specific Balance Confidence Scale. RESULTS: In the 10-meter walking test, the normal walking speed was significantly improved after the intervention in both the experimental group and the control group (p<.05). However, the fast walking speed was significantly improved only in the experimental group (p <.05). ln the community gait test, the experimental group showed significant improvement (p<.05), but the control group did not. Depression and self-efficacy were significantly improved in the experimental group (p<.05) but not in the control group. CONCLUSION: Community ambulation training may improve the gait ability of stroke patients and reduce their depression and improve self-efficacy.

• Journal of Ecology and Environment
• /
• 제40권2호
• /
• pp.89-106
• /
• 2016

Many plant species have two modes of reproduction: sexual and asexual. Both modes of reproduction have often been viewed as adaptations to temporally or spatially variable environments. The plant should adjust partitioning to match changes in the estimated success of the two reproductive modes. Perennial plants showed that favorable habitats in soil nutrients or water content tend to promote clonal growth over sexual reproduction. In contrast, under high light-quantity conditions, clonal plants tend to allocate more biomass to sexual reproduction and less to clonal propagation. On the other hand, plants with chasmogamous and cleistogamous flowers provides with a greater tendency of the opportunity to ensure some seed set in any stressful environmental conditions such as low light, low soil nutrients, or low soil moisture. It is considered that vegetative reproduction has high competitive ability and is the major means to expand established population of perennial plants, whereas cleistogamous reproduction is insurance to persist in stressful sites due to being strong. Chasmogamous reproduction mainly enhances established and new population. Therefore, the functions of sexual and asexual propagules of perennial or annual plants differ from each other. These traits of propagule thus determine its success at a particular region of any environmental gradients. Eventually, if environmental resources or stress levels change in either space or time, species composition will probably also change. The reason based on which the plants differ with respect to favored reproduction modes in each environmental condition, may be involved in their specific realized niche.

• 지능정보연구
• /
• 제17권2호
• /
• pp.23-38
• /
• 2011

에너지 관리는 센서, 컴퓨터나 가전기기와 같은 원천들의 에너지 소비를 최적화함으로써 재정적 생태적 성공을 달성하는 것이 목적이다. 따라서 각 원천들로부터 에너지 측정과 관련된 자료들을 획득하는 것이 에너지 관리의 출발점이다. 최근 상황인식 컴퓨팅을 아우르는 다른 인식컴퓨팅이라는 분야가 정보기술 영역에서 새롭게 부각되고 있다. 인식이란 생물체들의 생존을 위한 가장 기본적인 능력임과 동시에 인공지능의 도움으로 정보 시스템을 지능화하는 시발점이 될 수 있다. 이렇게 에너지 관리와 인식 컴퓨팅 연구가 상호 호혜적인 이익을 획득할 것임에도 불구하고 인식 컴퓨팅이 어떻게 에너지 관련 전략에 기여할 것인지에 대한 연구는 거의 존재하지 않는다. 따라서 본 논문의 목적은 에너지 관리 개선을 위한 인식 컴퓨팅 연구 이슈에 대해서 소개하는 것이다. 특히 인식 컴퓨팅이 에너지 절감과 사용자의 효용간의 균형을 실현하는 역할에 대해 집중하였다.