• The Journal of the Society of Korean Medicine Diagnostics
• /
• 제13권1호
• /
• pp.1-9
• /
• 2009

Objectives : If patients notice a symptom indicating inveterate dyspepsia but they don't have any problem around gastroscope, they get diagnosed as a functional dyspepsia or an imaginary stomach disease, but to overcome the limitations of these diagnoses, we are analyzing them for the common feature and are looking for a new diagnostics for them. Methods : Based on our survey with 122 patients with inveterate dyspepsia, we analyzed the period of onset, eating habits, the main symptoms, and observations on the gastroscope. We also analyzed the function of the stomach and intestines by EAV examinations, and the outer walls of the stomach and intestines by subdividing the level of coagulation into six with abdominal palpation. Results : We figured out that people who appeals about inveterate dyspepsia have had long period of onset, and that they had bad eating habits, shoulder stiffness, neck stiffness, headache, dizziness, etc. These are all the similar symptoms beside dyspepsia, which indicates that it is a syndrome. From about 70%, they didn't had particular problem in gastroscope, and as to be seen from the result of EAV examination, their stomachs and intestines had become functionless. Also, we were able to feel a stiffened tissue through abdominal palpation. Conclusion : Through this investigation, we found out that what the gastroscope can not find so that gets diagnosed as a functional dyspepsia or an imaginary stomach disease can be diagnosed as a syndrome called damjeok by overcoming the limitation utilizing the survey, EAV examinations, and abdominal palpation. We can find a mighty significance from the fact that it can be diagnosed as a syndrome.

• Journal of Communications and Networks
• /
• 제14권5호
• /
• pp.524-532
• /
• 2012

In this paper, we present the performance evaluation of the reliable cooperative media access control (RCO-MAC) protocol, which has been proposed in [1] by us in order to enhance system throughput in bad wireless channel environments. The performance of this protocol is evaluated with computer simulation as well as mathematical analysis in this paper. The system throughput, two types of average delays, average channel access delay, and average system delay, which includes the queuing delay in the buffer, are used as performance metrics. In addition, two different traffic models are used for performance evaluation: The saturated traffic model for computing system throughput and average channel access delay, and the exponential data generation model for calculating average system delay. The numerical results show that the RCO-MAC protocol proposed by us provides over 20% more system throughput than the relay distributed coordination function (rDCF) scheme. The numerical results show that the RCO-MAC protocol provides a slightly higher average channel access delay over a greater number of source nodes than the rDCF. This is because a greater number of source nodes provide more opportunities for cooperative request to send (CRTS) frame collisions and because the value of the related retransmission timer is greater in the RCO-MAC protocol than in the rDCF protocol. The numerical results also confirm that the RCO-MAC protocol provides better average system delay over the whole gamut of the number of source nodes than the rDCF protocol.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
• /
• 한국소음진동공학회 2005년도 추계학술대회논문집
• /
• pp.551-554
• /
• 2005

The method of the reduction of the automotive induction noise can be classified by the method of passive control and the method of active control. However, the passive control method has a demerit to reduce the effect of noise reduction at low frequency (below 500Hz) range and to be limited by a space of the engine room. Whereas, the active control method can overcome the demerit of passive control method. The algorithm of active control is mostly used the LMS (Least-Mean-Square) algorithm because the LMS algorithm can easily obtain the complex transfer function in real-time. Especially, When the Filtered-X LMS (FXLMS) algorithm is applied to an ANC system. However, the convergence performance of LMS algorithm goes bad when the FXLMS algorithm is applied to an active control of the induction noise under rapidly accelerated driving conditions. Thus Normalized FXLMS algorithm was developed to improve the control performance under the rapid acceleration. The advantage of Normalized FXLMS algorithm is that the step size is no longer constant. Instead, it varies with time. But there is one additional practical difficulty that can arise when a nonstationary input is used. If the input is zero for consecutive samples, then the step size becomes unbounded. So, in order to solve this problem. the Correlation FXLMS algorithm was developed. The Correlation FXLMS algorithm is realized by using an estimate of the cross correlation between the adaptation error and the filtered input signal to control the step size. In this paper, the performance of the Correlation FXLMS Is presented in comparison with that of the other FXLMS algorithms based on computer simulations.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
• /
• 한국소음진동공학회 2004년도 추계학술대회논문집
• /
• pp.1016-1019
• /
• 2004

The study of the noise reduction of an automobile has been concentrated on the reduction of the automotive engine noise because the engine noise is the major cause of automotive noise. However, many studies of automotive engine noise led to the interest of the noise reduction of the exhaust and intake system. The method of the reduction of the induction noise can be classified by the method of passive control and the method of active control. However, the passive control method has a demerit to reduce the effect of noise reduction at low frequency (below 500Hz) range and to be limited by a space of the engine room. Whereas, the active control method can overcome the demerit of passive control method. The algorithm of active control is mostly used the LMS (Least-Mean-Square) algorithm because the LMS algorithm can easily obtain the complex transfer function in real-time. Especially, Filtered-X LMS (FXLMS) algorithm is applied to an ANC system. However, the convergence performance of LMS algorithm goes bad when the FXLMS algorithm is applied to an active control of the induction noise under rapidly accelerated driving conditions. So, in order to this problem, the modified FXLMS algorithm using Moving Bandpass Filter was proposed. In this study, MBPF was implemented and use ANC for automotive intake under revived rapidly accelerated driving conditions and it was verified its performance.

• BMB Reports
• /
• 제52권9호
• /
• pp.566-571
• /
• 2019

Lymphoma is one of the most curable types of cancer. However, drug resistance is the main challenge faced in lymphoma treatment. Peroxisomal acyl-CoA oxidase 1 (ACOX1) is the rate-limiting enzyme in fatty acid ${\beta}$-oxidation. Deregulation of ACOX1 has been linked to peroxisomal disorders and carcinogenesis in the liver. Currently, there is no information about the function of ACOX1 in lymphoma. In this study, we found that upregulation of ACOX1 promoted proliferation in lymphoma cells, while downregulation of ACOX1 inhibited proliferation and induced apoptosis. Additionally, overexpression of ACOX1 increased resistance to doxorubicin, while suppression of ACOX1 expression markedly potentiated doxorubicin-induced apoptosis. Interestingly, downregulation of ACOX1 promoted mitochondrial location of Bad, reduced mitochondrial membrane potential and provoked apoptosis by activating caspase-9 and caspase-3 related apoptotic pathway. Overexpression of ACOX1 alleviated doxorubicin-induced activation of caspase-9 and caspase-3 and decrease of mitochondrial membrane potential. Importantly, downregulation of ACOX1 increased p73, but not p53, expression. p73 expression was critical for apoptosis induction induced by ACOX1 downregulation. Also, overexpression of ACOX1 significantly reduced stability of p73 protein thereby reducing p73 expression. Thus, our study indicated that suppression of ACOX1 could be a novel and effective approach for treatment of lymphoma.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
• /
• 한국정보통신학회 2021년도 춘계학술대회
• /
• pp.369-372
• /
• 2021

These days, people spend more time sitting at a desk for studies or work. Also, because people continue to use computers, smartphones, and tablet PCs often during break times, their posture is getting worse. Maintaining a position of bad posture for an extended period of time causes problems with the musculoskeletal system related to the neck, shoulders, and spine. Additionally, problems such as physical fatigue and posture deformation are predicted to expand to a wide range of age groups. Therefore, the core function of the system we are developing is to ensure correct sitting posture and to receive alert notifications via the created mobile application. To create the system, a flex sensor, pressure sensor, and tilt sensor are attached to a chair and utilized. The flex sensor detects and compares the amount of bending in the chair's posture and transmits this value to an Arduino Uno R3 board. Additionally, information such as body balance and incline angle are collected to determine whether or not the current sitting posture is correct. When the posture is incorrect, a notification is sent through the mobile application to indicate to the user and the monitoring app that their posture is not correct. The system proposed in this study is expected to be of great help in future posture-related research.

• Korean Journal of Animal Reproduction
• /
• 제6권1호
• /
• pp.19-30
• /
• 1982

1. The cows slaughtered at age of 3, 4, 6, 7, 8, and 9 years old were 1.5, 1.5, 15.0, 62.5 and 4.4% respectively. 2. The cows slaughtered at 351-450kg and more than 500kg were 60 and 28% respectively. 3. Best, very good, good and bad cows in nutritional condition were 1.6, 25.8, 62.9, and 9.7% respectively. Among the six cows which were bad nutrition, the two were with severe endometritis, the three were normal in genital function and one was on 70 days of pregnancy. 4. Holstein cows(55.2%) showed higher reproductive failure than the Korean cows(33.3%). 5. The slaughted ratio of the Korean cattle and Holstein cows was 36 and 64% respectively. 6. Pregnant cows were about 16% among the slaughtered one. 7. Reproductive failures were composed of 46% in uterus, 32% in ovaries, 8% in udder, 6% in oviduct, 4% in cervix of uterine, 2% in vagina and 2% inmummified fetus. 8. Forty six percentages of uterine diseases were as follows; horn, 13%, body of uterus, 32% and ovary diseases were 32%, that is, 12% of ovary atrophy, 8% of ovarycyst and 6% of lutealcyst. 9. The cows of reproductive failures were commonly infected with 1.6 kinds of diseases. 10. According to classification, six type of ovaries were as follows; normal, 58%, ovary-cyst, 11%, luteum cyst, 4%, coexistence of follicles and corpus luteum, 16%, weak function of ovaries, 10% and ovarian atrophy, 1%. 11. Major axis, minor axis and thickness of right ovary were larger than those of left one both in Korean cattle and Holstein cows. Holstein cow had generally larger size of ovary than these of the Korean cattle.. 12. The left and right oviducts showed no difference in length, but Holstein had longer oviduct than Korean cow. 13. There was no difference in the length of uterine horn between right and left in the Korean cows, but the right was longer than the left in Holstein cows. 14. Holstein had longer horn and body of uterine than the Korean cows. 15. The weight of right ovary was heavier than that of left in both breeds, but there was no differences in weight of left ovary between two breeds and right ovary of Holstein breed was heavier than that of the Korean cow. 16. The weight of right oviduct and uterine born was heavier than that of the left, and Holstein had heavier oviducts and uterine horns than the Korean cows. 17. Holstein had heavier uterine body and cervix of uterine than the Korean cows. 18. The length of reproductive systems of Korean cow is as follows; Major and minor diameter and thickness ofovary are 3.6${\pm}$0.7, 2.3${\pm}$0.4 and 1.6${\pm}$1.4 cm in left and 3.7${\pm}$0.6, 2.5${\pm}$0.5 and 1.8${\pm}$0.5 cm in right. Oviduct is 28.4${\pm}$3.1 cm in left and 27.8${\pm}$3.3 cm in right. Uterine horn is 27.4${\pm}$4.5 cm in left and 27.7${\pm}$4.9 cm in right. Uterine body and cervix are 3.4${\pm}$1.1 and 6.5${\pm}$1.7 cm. 19. The length of female reproductive systems ofHolstein cow is as follows; Major and minor diameter and thickness of ovary are 3.9${\pm}$1.3, 2.3${\pm}$0.5, and 1.5${\pm}$0.6 cm in left and 4.0${\pm}$0.8, 2.8${\pm}$0.6 and 1.8${\pm}$0.6 cm in right. Oviduct is 29.4${\pm}$4.2 cm in left and 29.3${\pm}$4.1 cm in right. Uterine horn is 30.2${\pm}$7.4 cm in left and 32.6${\pm}$8.4 cm in right. Uterine body and cervix are 4.5${\pm}$2.5 and 7.8${\pm}$2.9 cm. 20. The weight of reproductive systems of Korean cow is as follows; Ovary is 8.4${\pm}$4.1 g in left and 9.3${\pm}$3.6g in right. Oviduct is 1.5${\pm}$0.5 g in left and 1.6${\pm}$0.5 g in right. Uterine horn is 109${\pm}$27 g left and 118${\pm}$32 g in right. Uterine body and cervix are 30.4${\pm}$14.1 and 76.7${\pm}$38.4g. 21. The weight of reproductive systems of Holstein cow is as follows; Ovary is 8.2${\pm}$3.1 g in left and 12.5${\pm}$5.6 g in right. Oviduct is 1.7${\pm}$0.6 g in left and 1.9${\pm}$0.9 g in right. Uterine horn is 199${\pm}$14.2 g in left and 221${\pm}$111.2g in right. Uterine body and cervix are 58.2${\pm}$46.5 and 126.7${\pm}$103.3 g.

• YAKHAK HOEJI
• /
• 제30권5호
• /
• pp.253-265
• /
• 1986

Among 230 species of herbal drugs screened, thirty one show the anthelmintic activities in vitro against Clonorchis sinensis, the chinese liver fluke. The active substances have been isolated and their structures identified. Some of the active substances and their derivatives have been synthesized, followed by anthelmintic activity tests. The extracts from the active drugs cause damages in organs of the adult worm in the hepatic duct of rabbit. Some fresh water fish, which function as bad hosts for the fluke, excrete defense substances against the cercaria of the fluke. The defense substances have been isolated from Cyprinus carpio and Cyprinus carpio nudus, followed by structural identification. The results are summarized as follows: l) The bark of Machilus thunbergii as well as the seed of Schizandra chinensis contain meso-dihydro-guaiaretic acid as the anthelmintic component. Among derivatives synthesized, 4-phenyl-1-((3, 4-dihydroxyphenyl)-, 4-phenyl-1-(3-hydroxy-4-methoxy phenyl)-and 4-phenyl-1-(4-hydroxy-3-methoxy phenyl)-2, 3-dimethyl butanes show considerable activities. Administration of the bark extract mainly damages the bladder of the adult worm. 2) The active substance from the roasted fruit of Prunus mume is 2-hydroxymethylfurfural. This substance is produced during the roasting process. Administration of the fruitextract causes a damage of the bladder of the adult worm. 3) The active substance from the root of Scutellaria baicalensis is 5.2'-dihydroxy-6, 7, 8, 6'-tetramethoxyflavone. 4) Beside alantolactone, a very strong anthelmintic component is contained in the root of Inula helenium. Administration of the root extract causes irreversible damage on the worm, affecting mainly the reproductive organs. 5) The cercaricidal substances from the epidermis of C. carpio and C. carpio nudus are ethyl linoleate and linoleic acid, respertively. 6) The cercaricidal substances from various kinds of fresh water fish have different $R_f$ values, implying that the defense substances are species-specific. Unexpectedly, the fish with good host function, for example Pseudorasbora parva, excrete the defense substances, too. The defense substances are possibly organ-specific in individual species; the organs essenstial for the existence of the species excrete the defense substances, allowing other parts to be invaded by the cercaria. 7) The cercaricidal fraction of Carassius carassius is detected only in the fish which have been collected during the summer time from May to September, Its secretion is not dependent on water temperature. Thus, it seems to be possible that the secretion of the defense substance would be stimulated through a contact between the fish and cercaria.

• Journal of Life Science
• /
• 제22권5호
• /
• pp.613-620
• /
• 2012

To evaluate the effects of sleep habits on the powers of beta waves and the sensory motor rhythm of the electroencephalogram (EEG), female college student subjects were divided into four groups, according to their sleep habits, as follows: GSHG (Good Sleep Habit Group), CSHG (Common Sleep Habit Group: late bedtime), CSDG (Cognitive Sleep Disorder-Delayed Sleep Phase Syndrome Group), and NSDG (Non-cognitive Sleep Disorder-Delayed Sleep Phase Syndrome Group). Brain function was stimulated by reading a book for 3 min in the morning (9~12 am) and the EEG was measured. According to the results, the powers of the beta waves and sensory motor rhythm were not different during the resting period among the four groups. However, during the reading stimulation period, the powers of beta waves and the sensory motor rhythm in the GSHG were significantly greater than in the other groups ($p$ <0.05). Beta powers during stimulation also increased in all brain areas in the GSHG ($p$ <0.05). Interestingly, these were decreased in the frontal and temporal lobes in the CSHG by the reading stimulation ($p$ <0.05). On the other hand, sensory motor rhythm, which represents focusing efficacy, only improved in the GSHG. These results indicate that the brain's focusing function during the reading stimulation was not properly operating in the morning in the female college students who had a delayed bedtime and bad sleep habits.

• Journal of the Institute of Electronics Engineers of Korea CI
• /
• 제49권4호
• /
• pp.54-61
• /
• 2012

This paper proposes a fusion method of the queen-bee evolution into the rank-based control of mutation probability for improving the performances of genetic algorithms. The rank-based control of mutation probability which showed some performance improvements than the original method was a method that prevented individuals of genetic algorithms from falling into local optimum areas and also made it possible for the individuals to get out of the local optimum areas if they fell into there. This method, however, showed not good performances at the optimization problems that had a global optimum located in a small area regardless of the number of local optimum areas. We think that this is because the method is insufficient in the convergence into the global optimum, so propose a fusion method of the queen-bee evolution into this method in this paper. The queen-bee evolution inspired by reproduction process of queen-bee is a method that can strengthen the convergency of genetic algorithms. From the extensive experiments with four function optimization problems in order to measure the performances of proposed method we could find that the performances of proposed method was considerably good at the optimization problems whose global optimum is located in a small area as we expected. Our method, however, showed not good performances at the problems whose global optima were distributed in broad ranges and even showed bad performances at the problems whose global optima were located far away. These results indicate that our method can be effectively used at the problems whose global optimum is located in a small area.