• Title/Summary/Keyword: background prior

Search Result 660, Processing Time 0.029 seconds

ABO Blood Group, Epstein-Barr virus Infection and Prognosis of Patients with Non-metastatic Nasopharyngeal Carcinoma

  • Zhang, Ya-Xiong;Kang, Shi-Yang;Chen, Gang;Fang, Wen-Feng;Wu, Xuan;You, Hua-Jing;He, Da-Cheng;Cao, Ya-Lin;Liang, Wen-Hua;Zhang, Li
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.15 no.17
    • /
    • pp.7459-7465
    • /
    • 2014
  • Background: A prior study showed blood type A/AB to be associated with an increased risk of nasopharyngeal carcinoma (NPC) compared to subjects with blood type O. However, the relationship between ABO blood groups and prognosis of NPC patients is still questionable. In addition, whether Epstein-Barr virus (EBV) infection is associated with prognosis of NPC patients with different ABO blood groups is unclear. Materials and Methods: We conducted univariate and multivariable Cox regression analyses based on a consecutive cohort of 1,601 patients to investigate the above issues. Results: There was no significant difference in overall survival (OS) between different ABO blood groups (p=0.629), neither between A vs. non-A blood groups (p=0.895) nor AB vs. non-AB blood group (p=0.309) in univariate analyses and after adjusting for other factors. Interaction tests revealed that high immunoglobulin A against Epstein-Barr virus viral capsid antigen (VcA-IgA) level was associated with a favorable prognosis in male patients with UICC stage II disease who had an A blood type (p=0.008), compared with those with non-A blood type. In addition, male patients with an A blood group with a high blood lymphocyte level showeda tendency towards better survival in UICC stage III (p=0.096). Conclusions: ABO blood group status is not associated with the prognosis of patients with NPC. Additionally, blood group A male NPC patients with high VcA-IgA level or high blood lymphocyte counts might be correlated with a favorable prognosis in UICC stage II or III, respectively.

A Study of Forest Education Concept Mapping of Pre-Service Teachers and In-Service Teachers' for Young Children (숲교육(숲활동)에 대한 유아교사와 예비유아교사의 지식개념 연구)

  • Lee, Youn Sun;Kyun, Ju Youn;Lee, Si Eun;Lee, So Young
    • Korean Journal of Childcare and Education
    • /
    • v.10 no.4
    • /
    • pp.29-49
    • /
    • 2014
  • This study focused on how early childhood in-service teachers and pre-service teachers understood the concept of Forest Education. By applying the analysis of conceptual maps, introduced by Novak and Gowin's (1983, 1984), this study examined the number of upper category and subcategories, characteristics, hierarchy, and density of teachers' knowledge of Forest Education. 39 early childhood teachers and 60 pre-service teachers participated in this study. First, in-service teachers put 'nature(forest)' and 'living creatures' in the highest level of knowledge of Forest Education. On the other hands, pre-service teachers put 'the effect of Forest Education' and 'program' as well as 'nature(forest)' in the highest level of knowledge. In-service teachers seemed to construct their knowledge by understanding Forest Education as curriculum or activities such as math, language, music or multicultural education. Therefore they had a tendency to talk more about specific concepts including four seasons, insects, air, or climate change. However, pre-service teachers described 'the interconnectedness between human and nature', 'deep relationship with nature' and 'provision of nature.' This tendency might relate to their prior educational experiences of Eco-centered Early Childhood Education. With regards to the density and hierarchy of knowledge on Forest Education, both groups revealed the relatively low degree of density with average of around 2.00. This result can be interpreted that both groups of teachers might not have strong hierarchical and organizational knowledge of Forest Education. For the teacher education, philosophical background and practical knowledge of Forest Education should be included more.

A Study on 17th and 18th Century Common People's Costumes in France (17~18세기 프랑스 서민복식 연구)

  • Kim, Yang-Hee;Kim, Hyun-Joo
    • Journal of the Korean Society of Clothing and Textiles
    • /
    • v.36 no.9
    • /
    • pp.901-915
    • /
    • 2012
  • This study comparatively analyzes the characteristics, changes, and differences in class-based costume typology according to a concept of $17^{th}$ and $18^{th}$ century common people in France. The methods and contents are as follow. First, the scope of common people is grasped according to the historical background and a concept of $17^{th}$ and $18^{th}$ century common people in France. Second, through considering a prior research on analyzing the data of ancient documents on the economy of clothing, it classifies common people into bourgeoisie, urban common people, rural common people, and the destitute. It then examines diachronic evolution, and class-based synchronic difference in the consumption of $17^{th}$ and $18^{th}$ century common people's costumes in France. Third, it analyzes the appearance frequency by period according to type of common people's costumes, which were shown in pictorial materials with 283 sheets of engravings and 54 pieces of paintings; in addition, it reconstructs the succession and expansion in typology. It grasps differences and changes in morphology by class, space, and period of typology for common people's costumes. Common people's consumption of costumes was understood to have grown in qualitative aspects as well as a rise in the whole clothing demand. A class-based structure formed and indicated that a fashion cycle existed. As a result of analyzing common people's clothes (shown in pictorial materials of the $17^{th}$ and $18^{th}$ century) 41 items were grasped by gender and according to costume kind. Typology in common people's costumes (classified into bourgeoisie, urban common people, rural common people, and the destitute) showed a change by period. A change in typical costume typology was accepted more by the bourgeoisie than by urban and rural common people, and was accepted more by rural communities than by urban populations. Thus, a difference was formed through an expansion with a temporal difference that depended on class and space.

Measurement of Exchangeable Cations in Salt Accumulated Vinyl Greenhouse Soils (염류집적 비닐하우스 토양의 교환성 양이온 측정)

  • Chung, Jong-Bae;Lee, Yong-Se;Jeong, Byeong-Ryong
    • Korean Journal of Environmental Agriculture
    • /
    • v.37 no.1
    • /
    • pp.21-27
    • /
    • 2018
  • BACKGROUND: Although 1 M $NH_4OAc$ (pH 7.0) is predominantly used as the extractant of exchangeable cations in agricultural soils, this method is unsuitable for extracting the cations in saline and calcareous soils. This study was performed to select a proper method to determine exchangeable cations in vinyl greenhouse soils. METHODS AND RESULTS: Exchangeable cations (Ca, Mg, K, Na) in saline vinyl greenhouse soils were determined after extraction with 1 M $NH_4OAc$ (pH 7.0 and 8.5) and 1 M alcoholic $NH_4Cl$ (pH 8.5). Sum of exchangeable cations of the soils extracted with 1 M $NH_4OAc$ at pH 7.0 was 1.9-2.5 times greater than soil cation exchange capaity determined at pH 7.0, even though soluble salts were pre-removed. A similar result was found when the cations were extracted with 1 M $NH_4OAc$ at pH 8.5. Those results are mostly due to the overestimation of exchangeable Ca and Mg, linked to a partial dissolution of sparingly soluble salts in $NH_4OAc$ solution. When extracted with 1 M alcoholic $NH_4Cl$ at pH 8.5, extractable Ca and Mg decreased significantly due to the lower solubility of Ca and Mg carbonates in the extractant. And the sum of exchangeable cations was very close to the corresponding exchange capacity of soils. CONCLUSION: Alcoholic $NH_4Cl$ (pH 8.5) is proposed as a reliable extractant in determination of exchangeable cations in saline vinyl greenhouse soils. And soluble salts should be removed prior to the extraction of exchangeable cations.

An Study on the Role of Organizational Learning in the Technology Planning: An Empirical Study of Technology Planning on National R&D Program (기술기획 과정에 있어 조직학습을 통한 지식창출에 관한 연구: 국가연구개발사업 에너지R&D 과제기획에 대한 실증분석)

  • Kim, Bonggyun
    • Journal of Technology Innovation
    • /
    • v.21 no.1
    • /
    • pp.303-330
    • /
    • 2013
  • Korea has started new value creation which is the post catch-up innovation system from the catch-up innovation. Post catch-up innovation system is becoming the main R&D issue for Korea and is needed for the new concept of R&D management and planning frame. This study posed questionnaires : how to promote the knowledge creation in technology planning and what the role of organizational learning in the technology planning is. This paper suggests the relationship of success factors of knowledge creation in technology planning which is organized and operated by experts with different background. Based on the prior research on organizational learning, communications and collaborative interactions, four hypotheses that factors of knowledge creation in technology planning have positive relationship with organizational learning are extracted. This study adopts Structural Equation Modeling(SEM) to analyze the relationship between organizational learning and successful technology planning. The approach based on organizational learning and interaction will be useful for constructing the planning framework in the era of post catch-up innovation. This paper, therefore, suggests the possibility of new theoretical development and new research agenda.

  • PDF

Recent Trends of the Scientific Publication Patterns of Korean Thoracic and Cardiovascular Surgeons (대한민국 흉부외과 의사들의 논문저술경향의 변화)

  • Lim, Cheong
    • Journal of Chest Surgery
    • /
    • v.42 no.5
    • /
    • pp.561-565
    • /
    • 2009
  • Background: There haven't been any papers that have analyzed the recent trends in the changing attitudes and results of Korean thoracic and cardiovascular surgeons who submit scientific papers to the major cardiothoracic journals. Material and Method: I analyzed the original articles that were published in the major cardiothoracic surgery journals from 1995 to 2008 by Korean thoracic and cardiovascular surgeons. The data was retrieved from the internet websites of Pubmed, three major international SCI (Science Citation Index) journals and the Korean Journal of Thoracic and Cardiovascular Surgery. I then analyzed the data according to the chronological year, the subjects and the subspecialties. Result: The total number of original articles in the three international journals was 14,629. Among them, the number of articles written by Korean scientists was 157 (1.07%). A sharp increase was identified from 28 articles out of 7,674 articles (0.36%) prior to 2002, to 129 articles out of 6,955 articles (1.83%) after 2003. On the other hand, the annual number of articles in the Korean Journal was markedly decreased from 126.8 articles by 1999 to 80.0 articles after 2000. The annual number of articles in the Korean Journal was also decreased from 58.8% by 1999 to 48.3% after 2000. Conclusion: There was an observed increase in submitting articles to the international SCI journals after 2000 rather than to the Korean journal. The proportion of original articles in the Korean journal is also decreasing. I think we need to pay special attention to improve the quality and quantity of articles published in the Korean journal.

Pathologic Correlation of Serum Carcinoembryonic Antigen and Cytokeratin 19 Fragment in Resected Nonsmall Cell Lung Cancer

  • Lee, Seokkee;Lee, Chang Young;Kim, Dae Joon;Hong, Dae Jin;Lee, Jin Gu;Chung, Kyung Young
    • Journal of Chest Surgery
    • /
    • v.46 no.3
    • /
    • pp.192-196
    • /
    • 2013
  • Background: This study focused on the association between preoperative serum carcinoembryonic antigen (CEA) and cytokeratin 19 fragment (Cyfra 21-1) levels and pathologic parameters in patients with resected non-small-cell lung cancer (NSCLC). Materials and Methods: The records of 527 patients who underwent pulmonary resection of NSCLC were reviewed. The association between preoperative serum CEA and Cyfra 21-1 levels and variables that had p-values of less than 0.05 in a t-test or one-way analyses of variance was analyzed by multiple linear regression. Results: The mean serum CEA and Cyfra 21-1 levels prior to surgery were $6.8{\pm}23.1$ mg/dL (range, 0.01 to 390.8 mg/dL) and $5.4{\pm}12.3$ mg/dL (range, 0.65 to 140.2 mg/dL). The serum CEA levels were associated with tumor (T) and lymph node (N) stage and histology. The serum Cyfra 21-1 levels were associated with T stage, tumor size, and histology. Multiple linear regression indicated that serum CEA levels were associated with T (T3/4 vs. T1: ${\beta}$=8.463, p=0.010) and N stage (N2/3 vs. N0: ${\beta}$=9.208, p<0.001) and histology (adenocarcinoma vs. squamous cell: ${\beta}$=6.838, p=0.001), and serum Cyfra 21-1 levels were associated with tumor size (${\beta}$=2.579, p<0.001) and histology (squamous cell vs. adenocarcinoma: ${\beta}$=4.420, p=0.020). Conclusion: Serum CEA level was correlated with T and N stage, and Cyfra 21-1 with tumor size. CEA and Cyfra 21-1 showed histologic correlation. CEA is mainly elevated in adenocarcinoma and Cyfra 21-1 in squamous cell carcinoma. These results might be helpful for predicting pathologic status in preoperative NSCLC.

Studies on AIDS(Acquired Immune Defficiency Syndrome) Preventive Educational Programs Intended for Domestic and Foreign Industrial Workers (국내외 산업장 근로자의 AIDS(Acquired Immune Deficiency Syndrome)예방교육을 위한 소고)

  • Jung Moon-Hee;Cho Chung Min
    • Journal of Korean Public Health Nursing
    • /
    • v.10 no.1
    • /
    • pp.12-22
    • /
    • 1996
  • Currently. exchanges of industrial workers between countries are more active than ever. and the problem of AIDS in connection with the operation of preventive educational programs has reached a point where the issue cannot be limited to native people alone any more. Based on such judgement. this research has been carried out to provide basic study materials by grasping the latent factors representing the difference between countries in the levels of right knowledge. attitude and behavior with respect to AIDS maintained by workers who have grown in different social and cultural living background. During the period from Apr. 1. 1995 to Jun. 30. questionnaires. written both in Korean and English, were distributed to Korean and Malaysian employees working at certain Korean video manufacturers. and the results of replies. given by 80 workers who were analyzed through matched sampling· method where ages and sex matched by country. were used as the research materials. The gathered materials were analyzed through the SPSS package t-test. ANOVA. factor analysis and multiple stepwise regression methods. and the following results were obtained. 1. The 2 extracted latent factors could be named 'common. social' knowledge factor and 'in-depth. psychological' knowledge factor respectively. 2. The percentile points of 'external. social' knowledge factor. in the case of Korean workers. howed 90.0 at average. a figure 13.75 points higher than those of Malaysian workers. 76.25. On the other hand. the percentile points of the 'in-depth. psychological'knowledge factor showed 70.80 at average in the case of Korean workers. a figure 7.47 points lower than those of Malaysian workers. 78.33. Meanwhile. the difference in percentile points between the 2 latent factors was 8.54 at average. indicating that the points of 'in-depth. psychological' knowledge factor was lower than those of the 'external. social' knowledge factor. 3. As for Korean workers. the percentile points of the 'in-depth. psychological' knowledge factor showed higher points in office workers than in non-office workers. and such variables exhibited in the position of workers can explain the $7\%$ of the latent factor. The percentile points of the 'in-depth. psychological' knowledge factors. in the case of Malaysian workers. showed higher points in groups who had religion than in groups who did not. and higher points in groups who obtained information from newspapers than in groups who obtained from televisions or other sources; and with these 2 variables. $26\%$ of this latent factor can be explained. The results. of analysis described so far suggest that while Korean workers possessed general level of knowledge on AIDS. they had low level of practical knowledge as far as its depth is concerned. and that they had social prejudice on patients as well as on the AIDS infection route. In addition. because the overall knowledge level of Malaysian workers. is lower than that of Korean workers. it suggests that separate programs intended for Malaysian workers are required prior to executing integrated programs.

  • PDF

Optimal effect-site concentration of remifentanil for minimizing cardiovascular changes caused by fiberoptic nasotracheal intubation

  • Kim, Eun-Jung;Jeon, Hyun-Wook;Kim, Tae-Kyun;Baek, Seung-Hoon;Yoon, Ji-Uk;Yoon, Ji-Young
    • Journal of Dental Anesthesia and Pain Medicine
    • /
    • v.15 no.4
    • /
    • pp.221-227
    • /
    • 2015
  • Background: Endotracheal intubation induces clinically adverse cardiovascular changes. Various pharmacological strategies for controlling these responses have been suggested with opioids being widely administered. In this study, the optimal effect-site concentration (Ce) of remifentanil for minimizing hemodynamic responses to fiberoptic nasotracheal intubation was evaluated. Methods: Thirty patients, aged 18-63 years, scheduled for elective surgery were included. Anesthesia was induced with a propofol and remifentanil infusion via target-controlled infusion (TCI). Remifentanil infusion was initiated at 3.0 ng/mL, and the response of each patient determined the Ce of remifentanil for the next patient by the Dixon up-and-down method at an interval of 0.5 ng/mL. Rocuronium was administered after propofol and remifentanil reached their preset Ce; 90 seconds later fiberoptic nasotracheal intubation was initiated. Non-invasive blood pressure and heart rate (HR) were measured at pre-induction, the time Ce was reached, immediately before and after intubation, and at 1 and 3 minutes after intubation. The up-and-down criteria comprised a 20% change in mean blood pressure and HR between just prior to intubation and 1 minute after intubation. Results: The median effective effect-site concentration ($EC_{50}$) of remifentanil was $3.11{\pm}0.38ng/mL$ by the Dixon's up-and-down method. From the probit analysis, the $EC_{50}$ of remifentanil was 3.43 ng/mL (95% confidence interval, 2.90-4.06 ng/mL). In PAVA, the EC50 and EC95 of remifentanil were 3.57 ng/mL (95% CI, 2.95-3.89) and 4.35 ng/mL (95% CI, 3.93-4.45). No remifentanil-related complications were observed. Conclusions: The $EC_{50}$ of remifentanil for minimizing the cardiovascular changes and side effects associated with fiberoptic nasotracheal intubation was 3.11-3.43 ng/mL during propofol TCI anesthesia with a Ce of 4 ug/mL.

Support for a Campus Tobacco-Free Policy among Non-Smokers: Findings from a Developing Country

  • Yasin, Siti Munira;Isa, Mohamad Rodi;Fadzil, Mohd Ariff;Zamhuri, Mohammad Idris;Selamat, Mohamad Ikhsan;Ruzlin, Aimi Nadira Mat;Ibrahim, Nik Shamsidah Nik;Ismail, Zaliha;Majeed, Abu Bakar Abdul
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.17 no.1
    • /
    • pp.275-280
    • /
    • 2016
  • Background: A tobacco-free workplace policy is identified as an effective means to reduce tobacco use and protect people from second-hand smoke; however, the number of tobacco-free policies (TFP) remains very low in workplaces in Malaysia. This study explored the factors affecting support for a tobacco-free policy on two healthcare campuses in Malaysia, prior to the implementation of TFP. Materials and Methods: This cross-sectional study was conducted among 286 non-smokers from two healthcare training centres and two nearby colleges in Malaysia from January 2015 to April 2015. A standardized questionnaire was administered via staff and student emails. The questionnaire collected information on sociodemographic characteristics, support for a tobacco-free policy and perceived respiratory and sensory symptoms due to tobacco exposure. Bivariate and multivariate logistic regression analyses were performed to estimate the independent effects of supporting a tobacco-free campus. Results: The percentage of individuals supporting completely tobacco-free facilities was 83.2% (N=238), as opposed to 16.7% (N=48) in support of partially tobacco-free facilities. Compared to the supporters of partially tobacco-free facilities, non-smokers who supported completely tobacco-free health facilities were more likely to be female, have higher education levels, to be very concerned about the effects of other people smoking on their health and to perceive a tobacco-free policy as very important. In addition, they perceived that tobacco smoke bothered them at work by causing headaches and coughs and, in the past 4 weeks, had experienced difficulty breathing. In the multivariate model, after adjusting for sociodemographic characteristics and other factors, only experiencing coughs and headaches increased the odds of supporting a completely tobacco-free campus, up to 2.5- and 1.9-fold, respectively. Conclusions: Coughs and headaches due to other people smoking at work enhances support for a completely tobacco-free campus among non-smokers.