• Archives of Plastic Surgery
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• v.33 no.1
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• pp.39-45
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• 2006

This study is to examine the relationship between TGF-b1 expression and CTGF expression, and to evaluate the effect of Sp1 blockade on the expression of TGF-b1, CTGF and extracellular genes, clones of fibroblasts stably transfected with Sp1 decoy ODN. R-Sp1 decoy ODN was highly resistant to degradation by nucleases or serum, compared to the linear or phosphorothioated-Sp1 decoy ODN. Skin wounds were created on the back of 36 anesthetized rats. They were divided into four groups-the rats with normal skin, with wounded skin without decoy, with wounded skin injected with R-Sp1 decoy, and with wounded skin injected with mismatched R-Sp1 decoy, respectively. Skins were collected at 3rd, 5th, 7th, 14th day after wounding. Cellular RNA was extracted by RT-PCR analysis. TGF-${\beta}1$ and CTGF were deeply related with skin fibrosis during scar formation and it appeared that TGF-${\beta}1$ may cause the induction of CTGF expression. R-Sp1 decoy ODN inhibited TGF-${\beta}1$ and CTGF expression both in cultured fibroblasts and in the skin of rats. These results indicate that targeting Sp1 with R-type decoy efficiently blocks extracellular matrix gene expression, and suggest an important new therapeutic approach to control the scarring in normal wound healing and fibrotic disorders.

• Korean Journal of Veterinary Research
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• v.46 no.4
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• pp.305-313
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• 2006

The primary goal of the wound healing is rapid wound closure. Recent advances in cellular and molecular biology have greatly expanded our understanding of the biologic processes involved in wound repair and tissue regeneration. This study was conducted to develop a new sponge type of biomaterial to be used for either wound dressing or scaffold for tissue engineering. We designed to make a comparative study of the wound healing effect of silk fibroin/hyaluronic acid (SF/HA) blend sponge in full-thickness dermal injury model of rat. Two full-thickness excisions were made on the back of the experimental animals. The excised wound was covered with either the silk fibroin (SF), hyaluronic acid (HA) or SF/HA (7 : 3 or 5 : 5 ratio) blend sponge. On the postoperative days of 3, 7, 10 and 14, the wound area was calculated by image analysis software. Simultaneously, the tissues were stained with Hematoxylin-Eosin and Masson's trichrome methods to measure the area of regenerated epithelium and collagen deposition. In addition, we evaluated the degree of the epithelial cell proliferation using immunohistochemistry for proliferating cell nuclear antigen (PCNA). We found that the half healing time ($HT_{50}$) of SF/HA blend sponge treated groups were significantly decreased as compared with either those of SF or HA treatment group. Furthermore, SF/HA blend sponges significantly increased the size of epithelialization and collagen deposition as well as the number of PCNA positive cells on epidermal basement membrane as compared with those of control treatment. Especially, the 5 : 5 ratio group of SF/HA among all treatment groups was most effective on wound healing rate and histological studies. These results suggest that SF/HA blend sponges could accelerate the wound healing process through the increase of epithelialization, collagen deposition and basal cell proliferation in full thickness skin injury.

• Fire Science and Engineering
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• v.27 no.3
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• pp.38-46
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• 2013

Permanent water supply and water sprinkling systems are essential to protect major forests and facilities from forest fire. Back in 2005, Naksan Temple, a valuable cultural asset of Korea, was burned down in a forest fire that took place in Yangyang. This started a series of movements including installing water supply facilities and managing forests near important cultural assets. As for the existing facilities, however, they were installed without any standard guidelines for management and installation according to each constructor's specifications, which were based on the National Fire Safety Code 109. Unfortunately, this is not effective in protecting facilities from forest fires such as they have a small protection area, limited simultaneous sprinkling, and a difficult the movement of fire hose. Against this background, the study examines the condition of water supply facilities currently in use, identifies their deficiencies, and suggests how to improve the criteria for water supply service to effectively prevent forest fire. Specifically, three systems were proposed: Water Sprinkler Tower System for preventing spread of crown fires, and Forest Fire Hydrant System and Portable Water Spray System to be effective for suppressing surface fires. In addition, the standards on the performance and components of water pumps are also suggested.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.21 no.3
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• pp.269-275
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• 2003

The cadastral system which accomplishes the base of national land administration with accuracy of proper data and the cadastral maintenance quickly is agreeing with the actual place in information ages in Inundation. But even in spite of many efforts, various Problems are exposed in accuracy of the data on the cadastral maps and local situation must agree accurately from the process which propels cadastral information systems. Therefore, it must be carried out the cadastral non correspondence arrangement first of all in link of the plan which it corrects the error of existing data and computerization quickly. It summarizes the research as follows ; Cadastral non correspondence of the land boundaries on the map and actual circumstance does not agree with cadastral maps accurately, The lands which exceed the standards with the position error excess of 50cm on lil ,200 and 240cm on 1/6,000 areas on the map scale are the registration correction objectives. It is investigated that the cadastral non correspondence parcels occur in various cause and long period, the area error corrections are mainly objectives, and about 80% of the test area comes to reveal within permitted the limit of the measurement of planimetric area for cadastral survey, so it is not difficult with the fact that the compensation back which it follows in area increase and decrease and the location error correction becomes the important object fer the cadastral non correspondence arrangement projects.

• Korean Journal of Agricultural and Forest Meteorology
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• v.15 no.4
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• pp.320-331
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• 2013

The National Center for AgroMeteorology (NCAM) has designed a risk management solution for individual farms threatened by the climate change and variability. The new service produces weather risk indices tailored to the crop species and phenology by using site-specific weather forecasts and analysis derived from digital products of the Korea Meteorological Administration (KMA). If the risk is high enough to cause any damage to the crops, agrometeorological warnings or watches are delivered to the growers' cellular phones with relevant countermeasures to help protect their crops against the potential damage. Core techniques such as scaling down of weather data to individual farm level and the crop specific risk assessment for operational service were developed and integrated into a cloud based service system. The system was employed and implemented in a rural catchment of 50 $km^2$ with diverse agricultural activities and 230 volunteer farmers are participating in this project to get the user-specific weather information from and to feed their evaluations back to NCAM. The experience obtained through this project will be useful in planning and developing the nation-wide early warning service in agricultural sector exposed to the climate and weather extremes under climate change and climate variability.

• Korean Journal of Applied Biomechanics
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• v.19 no.1
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• pp.37-47
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• 2009

This study develops a technique training program to enhance the completion of Kolman, the high air flight technique, and applies it to two national athletes of the horizontal bar, one of the gymnastic events, for eight weeks. After that, their improvement was measured through 3D motion analysis to help them elevate their performance. The training program includes swing, hand release, twist, and bar hold, and its implementation produced the results stated below. They were made to practice the motion in the following way. After the hand-standing of giant swing which initiates the motion, they lift their body upward a little bit more. Next, they take their body down almost like a vertical descent and make a deep tap swing. Instead of doing the tap swing which widens the flection of hip and shoulder joints, while body revolution is more emphasized in particular, they release the bar as raising the centroid of their body sufficiently. During the flight, they try to narrow every joint in their body. As a result, the bar's elasticity becomes greatly increased, and since the backing rate of their body gets higher, the centripetal force of the swing is improved that they can release the bar in the higher position. In addition, because they can erect their body faster during the flight, they can perform comfortable twist and revolution in the air. They can also adjust the direction of the flight easily without too much concern for the proper timing of hand release as they rise. Thereby, they can not only maintain adequate distance from the bar for the bar hold but also ensure enough distance for body revolution and twist.

• Korean Journal of Applied Biomechanics
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• v.19 no.4
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• pp.671-680
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• 2009

We performed a study to obtain kinematic data on the characteristics of spike serving techniques used by volleyball players, including other basic data that will be useful for in-field applications. We used three-dimensional videography to compare good tough serves and serve errors. The subjects were 3 left attackers whose spike serves were videographed (60 fileds/s). The three-dimensional coordinates were calculated using the direct linear transformation method and then analyzed using the Kwon 3D software program version 3.1. There was no difference in time elapsed. However, the vertical displacement of the center of body mass(CM) differed between the 2 types of serves: in successful serves, the CM tended to be lower, as did the maximum ball height at the time of hitting. Further, the higher the level of the hitting hand was at the moment of impact, the higher was the likelihood of scoring points. In good serves, the players tended to accelerate their CM movement just before jumping to hit the ball and descend rapidly at the moment of hitting. The hand speed along with ball velocity during the impact was proven to be higher in successful serves. Moreover, in successful serves, the shoulder angles increased to a greater extent while the elbow angles were maintained constant. This possibly resulted in faster and more precise serves. An important observation was that the angle of trunk inclination during the jump did not increase with the swing of the shoulders, muscle tendon complex.

• Journal of Trauma and Injury
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• v.23 no.2
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• pp.163-169
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• 2010

Purpose: Spinal epidural hematoma (EDH) is a rare condition requiring an urgent diagnosis and management. We describe here the clinical features, magnetic resonance image (MRI) findings, and outcomes of surgery in six patients with spinal EDH. Methods: We retrospectively analyzed six patients who underwent surgery for spinal EDH between April 2004 and May 2010. Preoperative MRI findings within 48 hours of symptom occurrence were analyzed for cord compression, extent of EDH, and presence of vascular abnormalities. Pre- and postoperative neurological status was also assessed comparatively. Results: Our six patients consisted of three men and three women, with a mean age of 70 years (range: 54-88 years), who presented with the back pain or motor weakness. The mean follow-up period was 34 months (range: 2-72 months). Two patients had cardiovascular disease and were taking warfarin, but the others had no history of medical comorbidity. Those two patients taking warfarin had a history of trauma, another one experienced symptoms during a strenuous effort, and the others developed spontaneously. Before surgery, motor power was grade III in three patients, grade 0 in two patients, and normal in one patient. Preoperative MRI showed no vascular abnormalities except for the EDH in any patient. At the last follow-up, all those five patients with motor weakness showed neurological improvement compared to their preoperative status. There were no complications related to surgery. All six patients were able to ambulate with or without an assistive device. Conclusion: Spinal EDH can occur in patients without trauma, bleeding diathesis, or combined vascular pathology. The surgical outcomes of spinal EDH seem to be satisfactory, even in quadriplegic patients.

• Journal of Korea Water Resources Association
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• v.46 no.7
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• pp.697-706
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• 2013

In recent, Korea has faced on water quality management problems in reservoir and river because of increasing water temperature and rainfall frequency caused by climate change. This study is effectively to manage water quality for establishment of algal bloom forecasting models with artificial neural network. Daecheong reservoir located in Geum river has suitable environment for algal bloom because it has lots of contaminants that are flowed by rainfall. By using back propagation algorithm of artificial neural networks (ANNs), a model has been built to forecast the algal bloom over short-term (1, 3, and 7 days). In the model, input factors considered the hydrologic and water quality factors in Daecheong reservoir were analyzed by cross correlation method. Through carrying out the analysis, input factors were selected for algal bloom forecasting model. As a result of this research, the short term algal bloom forecasting models showed minor errors in the prediction of the 1 day and the 3 days. Therefore, the models will be very useful and promising to control the water quality in various rivers.

• Food Science of Animal Resources
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• v.28 no.2
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• pp.187-195
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• 2008

The purpose of this study was to establish proper shipping weight and backfat thickness by applying the growth model to backfat thickness, measured by means of not only body weight, but also ultrasonography, and predicting the changes by age. Three breeds, i.e. Duroc, Landrace, and Yorkshie, were analyzed, and the Gompertz, logistic, and Von Bertalanffy model were used for inference with the parameter of the growth model being sex. As a result, both body weight and backfat thickness showed different growth curve parameters and characteristics at inflection points depending on model selection and sex. As for backfat thickness, in estimating the inflection point, unlike the case of body weight, the inflection ages of the boars of the Duroc breed was earlier than that of sows, whereas the inflection ages of the sows of the Landrace and Yorkshire breeds was earlier than that of boars. More than anything else, in the analysis of the changes in backfat thickness according to body weight, as the body weight reached 145kg, the backfat thickness showed much variation as great as 1.7-3.2 cm in each breed and sex. In addition, unlike the other breeds, the boars of the Landrace breed showed an exponential type of relationship between body weight and backfat thickness. As they grow to become 100 kg or heavier, abrupt change in back fat thickness was confirmed. If the growth of body weight and backfat thickness is understood and the genetic relationship is taken advantage of like this, it would be possible to set desired body weight and backfat thickness, and thus help effectively set the shipping time. If not only the phenotype, but also genetic parameters about growth characteristics are estimated and analyzed additionally, more effective data can be generated.