• 제목/요약/키워드: azalea

검색결과 48건 처리시간 0.026초

TRAIL and Bortezomib: Killing Cancer with Two Stones

  • Qureshi, Muhammad Zahid;Romero, Mirna Azalea;Attar, Rukset;Javed, Zeeshan;Farooqi, Ammad Ahmad
    • Asian Pacific Journal of Cancer Prevention
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    • 제16권4호
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    • pp.1671-1674
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    • 2015
  • Cancer genomics and proteomics have undergone considerable broadening in the past decades and increasingly it is being realized that solid/liquid phase microarrays and high-throughput resequencing have provided platforms to improve our existing knowledge of determinants of cancer development, progression and survival. Loss of apoptosis is a widely and deeply studied process and different approaches are being used to restore apoptosis in resistant cancer phenotype. Modulating the balance between pro-apoptotic and anti-apoptotic proteins is essential to induce apoptosis. It is becoming more understood that pharmacological inhibition of the proteasome might prove to be an effective option in improving TRAIL induced apoptosis in cancer cells. Keeping in view rapidly accumulating evidence of carcinogenesis, metastasis, resistance against wide ranging therapeutics and loss of apoptosis, better knowledge regarding tumor suppressors, oncogenes, pro-apoptotic and anti-apotptic proteins will be helpful in translating the findings from benchtop to bedside.

몇 가지 자생 지피식물의 차광에 따른 생장반응 (Growth Reaction of Some Ground Cover Plant in Korean Native Greening according to Shading Levels)

  • 김귀순;이정식
    • 화훼연구
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    • 제17권2호
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    • pp.75-80
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    • 2009
  • 본 연구는 음지에서 잘 자라는 자생 지피식물 선발을 위해 7종의 자생식물을 대상으로 광 조건을 달리하여 생장반응을 조사하였다. 비비추는 자연광의 60% 차광에서 가장 좋은 생장을 보였으며, 맥문동은 90% 차광에서 생육이 매우 좋았다. 관중은 60% 차광에서 생육이 가장 우수 하였으며, 대사초는 40% 차광에서 초장과 초폭이 신장이 좋았고 엽수도 많았다. 비비추, 맥문동, 관중 및 수호초는 차광율이 높을수록 엽록소 함량이 점차 증가되었으며, 맥문동은 완전음지나 자연광에서는 개화되지 않았다.

A Comparative Analysis of the Accuracy of Areal Precipitation According to the Rainfall Analysis Method of Mountainous Streams

  • Kang, Bo-Seong;Yang, Sung-Kee;Kang, Myung-Soo
    • 한국환경과학회지
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    • 제28권10호
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    • pp.841-849
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    • 2019
  • The purpose of this study was to evaluate the method of estimating the areal precipitation reflecting the altitude of the mountainous terrain on Jeju Island by comparing and analyzing the areal precipitation using the Thiessen polygon method and the isohyetal method in mountainous streams. In terms of constructing the Thiessen polygon network, rainfall errors occurred in 94.5% and 45.8% of the Thiessen area ratio of the Jeju and Ara stations, respectively. This resulted in large areal precipitation and errors using the isohyetal method at altitudes below 600 m in the target watershed. In contrast, there were small errors in the highlands. Rainfall errors occurred in 18.91% of the Thiessen area ratio of Eorimok, 2.41% of Witseoreum, and 2.84% of Azalea Field because of the altitudinal influence of stations located in the highlands at altitudes above 600 m. Based on the areal precipitation estimation using the Thiessen polygon method, it was considered to be partially applicable to streams on Jeju Island depending on the altitude. However, the method is not suitable for mountainous streams such as the streams on Jeju Island because errors occur with altitude. Therefore, the isohyetal method is considered to be more suitable as it considers the locations of the rainfall stations and the orographic effect and because there are no errors with altitude.

Headspace GC-MS Analysis of Spring Blossom Fragrance at Chungnam National University Daedeok Campus

  • Choi, Yeonwoo;Lee, Sanghyun;Kim, Young-Mi;Nguyen, Huu-Quang;Kim, Jeongkwon;Lee, Jaebeom
    • Mass Spectrometry Letters
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    • 제13권4호
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    • pp.125-132
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    • 2022
  • There are many types of spring blossoms on the Daedeok campus of Chungnam National University (CNU) at the area of 1,600,000 square meters. As an assignment for the class of Analytical Chemistry I for second-year undergraduate students, 2021, flower petals collected from various floral groups (Korean azalea, Korean forsythia, Dilatata lilac, Lilytree, Lily magnolia, and Prunus yedoensis) were analyzed using headspace extraction coupled to gas chromatography-mass spectrometry (HS-GC-MS) to study the aromatic profiles and fragrance compounds of each sample group. Various types of compounds associated with the aroma profiles were detected, including saturated alcohols and aldehydes (ethanol, 1-hexanol, and nonanal), terpenes (limonene, pinene, and ocimene), and aromatic compounds (benzyl alcohol, benzaldehyde). The different contribution of these compounds for each floral type was visualized using statistical tools and classification models based on principal component analysis with high reliability (R2 = 0.824, Q2 = 0.616). These results showed that HS-GC-MS with statistical analysis is a powerful method to characterize the volatile aromatic profile of biological specimens.

Exobasidium japonicum에 의한 영산홍 떡병 (Leaf Gall of Rhododendron indicum Caused by Exobasidium japonicum in Korea)

  • 권진혁;채윤석
    • 식물병연구
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    • 제12권3호
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    • pp.284-286
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    • 2006
  • 경남 진주시 정촌면 강주연못, 금산면 가정집 정원수로 심은 영산홍 잎에 떡병이 심하게 발생하였다. 병징은 잎에 발생하여 흰색의 가루같은 자실층이 생기고 이상비대를 한다. 병반부에서 자실체가 잎 앞, 뒷면으로 노출되고 흰색의 전형적인 떡모양으로 된다. 담자기는 무색, 곤봉 모양의 원주형이며 $1{\sim}5$개 정도의 작은 자루모양을 하고 있으며 크기는 $8{\sim}35{\times}3{\sim}6{\mu}m$였다. 담자포자는 무색, 단포이며 장타원형 모양의 원주형으로 아랫부분은 약간 굽었으며 크기는 $10{\sim}22{\times}3{\sim}5{\mu}m$였다. 영산홍에서 병원성을 검정하였다. 잎에 발생한 병징과 병원균의 균학적 특징을 조사한 결과, 이 병을 Exobasidium japonicum Shirai에 의한 영산홍 떡병으로 명명하여 국내에 처음 보고한다.

진달래꽃으로부터 분리된 플라보노이드 화합물의 항산화성에 관한 연구 (Antioxidative Activity of Flavonoids Isolated from Jindalrae Flowers (Rhododendron mucronulatum Turcz.))

  • 김미애;;정태영
    • Applied Biological Chemistry
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    • 제39권4호
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    • pp.320-326
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    • 1996
  • 우리나라에서 식용으로 이용되는 진달래꽃으로부터 7성분의 항산화성이 있는 플라보노이드 화합물이 분리 동정되었다. 이들 화합물의 구조는 IR, UV, FAB-MS, $^1H\;NMR$$^{13}C\;NMR$에 의해서 얻어진 분광학적인 결과에 근거하여 afzelin, ampelopsin, catechin, myricetin, myricitrin, quercetin 및 quercitrin인 것으로 밝혀졌다. 이들 화합물은 2개의 flavonol, 3개의 flavonol glycoside, 1개의 flavane 및 1개의 dihydroflavonol로 이루어졌다. 에틸에테르 및 초산에틸 구분에 존재하는 flavonol glycoside (14.4 g)는 polyamide C-200 관 크로마토피법, 분취용 박층크로마토그래피법, 재결정화법, sephadex LH-20 관 크로마토그래피법을 통해서 양쪽 구분으로부터 최종적으로 회수된 총 flavonoid량 (17.6g의 82%에 달하였다. 항산화성은 티오시안산철의 존재하에서 리놀레산의 에타놀용액 중에서 측정되었다. 항산화 효능성은 afzelin<$\alpha-tocopherol$

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의도적으로 철쭉 섭취 후 발생된 성인 전신 중독 증상 1례 (A case of Systemic Toxicity that Occurred in an Adult Who Intentionally Ingested Rhododendron Sclippenbashii)

  • 정상민;이승한;임정수;윤상열;유승;이진웅;김승환;유인술;유연호
    • 대한임상독성학회지
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    • 제7권2호
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    • pp.180-182
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    • 2009
  • It is well known that Rhododendron sclippenbashii contains the toxic material grayanotoxin. So, Koreans do not eat it, but they do eat azalea although it contains grayanotoxin. That is why there have been no reports about Rhododendron sclippenbashii intoxication after ingesting it intentionally, not accidentally. In this case, the patient was admitted to the emergency room with several toxic symptoms after intentionally consuming 50 blossoms of Rhododendron sclippenbashii to get rid of thirst. Treatment with saline infusion and atropine was successful and the outcome was favorable enough in this case to produce a complete cure without any sequelae at discharge. But toxic symptoms were seen for 24 hours, although the symptoms usually fade in 9 hours. Therefore, we should carefully treat and observe, for over 24 hours, the patient who intentionally ingests about 50 blossoms of Rhododendron sclippenbashii.

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진달래꽃으로부터 분리된 페놀산 화합물의 항산화성에 관한 연구 (Antioxidative Activity of Phenolic Acids Isolated from Jindalrae Flower (Rhododendron mucronulatum Turzaninow))

  • 김미애;;정태영
    • Applied Biological Chemistry
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    • 제39권6호
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    • pp.506-511
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    • 1996
  • 우리나라에서 식용으로 이용되는 진달래꽃으로부터 6성분의 폐놀산 화합물이 분리동정되었다. 이들 화합물의 구조는 IR, UV, $^{1}H$$^{13}C$ NMR, FAB-MS, ES-MS와 EI-MS에 의해 얻어진 분광학적인 결과에 근거하여, chlorogenic acid, 3,5-O-dicaffeoylquinic acid, 4,5-O-dicaffeoylquinic acid, caffeic acid, ferulic acid, p-coumaric acid인 것으로 밝혀졌다. Chlorogenic acid (0.2 g)는 ethyl acetate과 ethyl ether 분획에 동시에 함유되어 있었고, polyamide C-200 관 크로마토그래피법, 분취용 박층크로마토그래피법, 재결정법, Sephadex LH-20 관 크로마토그래피법을 통해서 양 구분으로부터 최종적으로 회수된 총 페놀산 함량 (0.52 g)의 38.5%를 차지하였다. 항산화성은 티오시안산철의 존재하에서 리놀레산의 에타놀 용액 중에서 측정되었다. 항산화능은 p-coumaric acid<${\alpha}-tocopherol$

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조선시대(朝鮮時代) 술에 관한 분석적(分析的) 고찰(考察) -조선중기(朝鮮中期) 1600 년대(年代)를 중심(中心)으로- (A Study on Wine of Yi Dynasty in 1600)

  • 최종희;이효지
    • 한국식생활문화학회지
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    • 제2권1호
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    • pp.17-24
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    • 1987
  • As people know how to brew a wine from fruits and cereals, they continued to develope various wines good to their taste. Korean wines are also ones made from cereals and they have long been eager to improve the delicate taste. They used to drink Takju, raw rice wine, made from nonglutinous rice and Nuruk, a kind of yeast starter. During Koryo Dynasty, Soju a liquor was imported from Won(the Chinese dynasty). Nowadays this traditional folk wine, which had been developed variously and drunk all over the country, is decreasing year after year. The purpose of this study was to review on the wines ; its kinds, raw materials, brewing method, manufacturing utensils, measuring units and devices and the terms for wine making based on 20 documents published in 1600, in the middle of Yi dynesty. The results of review were as follows. 1. There were 121 kinds of wines at that time in Korea. 2. Among the raw materials for wines, major materials were glutinous rice, nonglutinous rice, wheat flour, wheat, mung bean, and black soybean. And minor materials were pepper corn, Lycium chinenisis, cinnamon, pine needles, pine nuts, jujube, mugwort leaves, lotus leaves, pine corn, pine bud, chrysanthemum, pine flowers, honey, Acanthopanox seoultenses, bamboo-root, marrowbone of blak cow, sweet flag, Ciprus noblis, Saurea lappa, honey suckle, Tricho santhes, azalea, the leaves of the paper mulberry, and bark of chungum tree. 3. There were several kinds of wines such as a wine without using Nuruk, a wine made from glutinous rice, nonglutinous rice, or glutinous and nonglutinous rice with flour. 4. There were several brewing methods for wines such as a wine boiled with ring rice cake, a wine brewed with loaves of rice cake, a wine brewed with hard boiled rice, a wine brewed with rice gruel, and a wine brewed with powdered rice gruel. 5. There were 23 kinds of utensils including measuring devices for weight and volume.

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산불지역의 토양동물에 관한 연구 (A Study on Soil Animal in the Forest Fire Area)

  • 손홍인;최성식
    • 한국토양동물학회지
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    • 제5권2호
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    • pp.47-62
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    • 2000
  • 본 연구는 산불이 토양 동물에 미치는 영향을 조사한 것으로써 1997년 4월 11일에 약 50 ha 정도 화재가 발생한 경남 하동군 횡천면 전대리에 위치한 야산에서 실시되었다. 조사 지역의 식생은 흉고직경 7-14cm, 20-30넌생 소나무가 절대적인 우점종이며 그 밖에 참나무와 수목과 때죽나무, 개옻나무, 진달래, 관목류 등의 혼합림이며, 초본류로 구성되어 있는 지표층은 비교적 단순한 지역이며, 화재지역은 부엽층(약 10cm)이지만, 비화재지역은 낙엽.낙지와 부식층 및 지피식물들이 풍부한지역이다. 토양미소절지동물들은 계절에 따른 밀도와 환경 인자와의 관계를 연구하였으며, 중.대형 동물은 계절에 따른 밀도와 생체중이 환경 인자와 어떠한 관계가 있는지 알아보았다. 그 결과를 요약하면 다음과 같다. 1. 토양미소절지동물은 7강 24목에 257,087개체수이며, 중.대형 동물은 7강 22목에 8,006개체수가 검출되었으며, 검출된 개체군은 거미강, 곤충강, 지네강, 결합강, 노래기강, 연갑강, 빈모 강등이었다. 2. 토양미소절지동물은 전체 257,057개체수중에서 거미강이 70.9%로 가장 높은 개체수 비율을 나타냈으며, 곤충강이 28.4%로 나타나 이들 2군의 합계가 99.45%로 절대적인 우위를 보였고, 중.대형동물에서는 전체 8.006개체수중에서 곤충강이 57.6%로 가장 높은 개체수비율을 보였으며 다음이 지네강으로서 23.8%의 비교적 높은 비율을 나타냈다.

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