• KOREAN ASSOCIATION OF OCCUPATIONAL HEALTH NURSES
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• v.15 no.2
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• pp.14-18
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• 2008

• IMMUNE NETWORK
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• v.13 no.1
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• pp.34-41
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• 2013

Interleukin-18 (IL-18) has been known to induce interferon-${\gamma}$ (IFN-${\gamma}$) production and promote Th1 immunity. Although mammalian IL-18 has been characterized in great detail, the properties and application of chicken IL-18 remain largely uninvestigated as of yet. In this study, we evaluated the immunomodulatory properties of Salmonella enterica serovar Typhimurium expressing chicken interleukin-18 (chIL-18) on immune responses induced by avian influenza (AI) and Newcastle disease (ND) vaccines. After oral administration of S. enterica serovar Typhimurium expressing chIL-18, chickens were vaccinated intramuscularly with the recommended dose of either inactivated AI H9N2 vaccine or ND (B1 strain) vaccine. Chickens receiving a primary vaccination were boosted using the same protocol 7 days later. Humoral and cell-mediated immune responses were evaluated in terms of HI antibody titers and proliferation and mRNA expression of IFN-${\gamma}$ and IL-4 of peripheral blood mononuclear cells (PBMC) in response to specific antigen stimulation. According to our results, oral administration of S. enterica serovar Typhimurium expressing chIL-18 induced enhanced humoral and Th1-biased cell-mediated immunity against AI and ND vaccines, compared to that of chickens received S. enterica serovar Typhimurium harboring empty vector. Therefore, we conclude that our proposed vaccination regimen using inactivated AI and ND viruses along with oral administration of S. enterica serovar Typhimurium expressing chIL-18 may provide a novel approach in protecting chicken from currently circulating AI and ND virus strains.

• Korean Journal of Veterinary Service
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• v.43 no.3
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• pp.167-171
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• 2020

The epidemiological investigation of outbreak in korea confirmed that the inflow of avian influenza (AI) is related to the migration of migratory birds. In this study, avian repellents instrument were implemented and developed using the visual effects of lasers in accordance with the situation of small domestic fowl farms, and monitoring cameras were installed around each instrument to investigate the frequency of wild birds appearing and evaluate the performance of the instrument. Observation showed that the appreance ratio was reduced by 95%, and no significant reduction in the intrusion prevention effect by adaptation was observed on all fowl farms. In conclusion, it is expected that the outbreak of wild bird-borne infectious diseases such as avian influenza will be decreased if the device is installed on domestic fowl farms.

• Journal of the Korea Organic Resources Recycling Association
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• v.24 no.4
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• pp.49-57
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• 2016

In this study, a thermal hydrolysis technology was used to treat the poultry carcasses that were killed due to Avian Influenza (AI) occurrence, as well as to determine the possibility of fueling for the resultant products. Experimental results showed that the poultry carcasses were liquefied except for sand, and showed the optimum efficiency at $190^{\circ}C$ and operating time of 60 minutes. It has been shown that liquid products obtained after thermal hydrolysis has good conditions for fuel conversion since it had high carbon contents and calorific value, as well as low ash content. In addition, it was possible to operate the thermal hydrolysis facility by using only the waste heat generated in the combustion without injecting the auxiliary fuel, and the exhaust gas generated in the combustion has a small influence on the atmosphere.

• KOREAN POULTRY JOURNAL
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• v.38 no.8 s.442
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• pp.142-143
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• 2006

조류 인플루엔자(Avian influenza, 이하 AI)는 때로는 돼지에서 나타나기도 하지만 주로 가금류에만 감염되는 바이러스성 질병이다 . 본래 “ influenza”는 라 틴 어 의“influential “(영어: influence), “영향을 주다”에서 유래된 말로 옛날 서양인들이 전염병이 돌면 별자리의 영향에 의한 것으로 믿은 것에서 유래됐다 한다. AI는 매우 종특이적(species- specific)이나, 드물게 종을 넘어 인간에게까지도 감염력을 나타내는 것들도 있다. 야생이 아닌 인간이 사육하는 가금류에서는 약독성과 맹독성의 두 종류가 발견되는데 이들은 아주 극단적인 결과를 나타낸다. 약독성은 깃이 곤두서거나 산란율이 저하되는 정도로 미미하게 경과되는 반면, 맹독성은 계군 간의 전파속도가 빠르고 각종 장기들에 감염되어 48시간 이내에 100% 치사율을 보이기도 한다.

• Korean Journal of Poultry Science
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• v.50 no.1
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• pp.41-50
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• 2023

Over the last decade, avian influenza (AI) has been considered an emerging disease that would become the next pandemic, particularly in countries like South Korea, with continuous animal outbreaks. In this situation, risk assessment is highly needed to prevent and prepare for human infection with AI. Thus, we developed the risk assessment matrix for a high-risk area of human infection with AI in South Korea based on the notion that risk is the multiplication of hazards with vulnerability. This matrix consisted of highly pathogenic avian influenza (HPAI) in poultry farms and the number of poultry-associated production facilities assumed as hazards of avian influenza and vulnerability, respectively. The average number of HPAI in poultry farms at the 229-municipal level as the hazard axis of the matrix was predicted using a negative binomial regression with nationwide outbreaks data from 2003 to 2018. The two components of the matrix were classified into five groups using the K-means clustering algorithm and multiplied, consequently producing the area-specific risk level of human infection. As a result, Naju-si, Jeongeup-si, and Namwon-si were categorized as high-risk areas for human infection with AI. These findings would contribute to designing the policies for human infection to minimize socio-economic damages.

• Smart Media Journal
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• v.7 no.1
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• pp.45-51
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• 2018

Avian influenza (AI) is notorious for its rapid infection rate, and has a serious impact on consumers and producers alike, especially in poultry farms. The AI outbreak, which occurred nationwide at the end of 2016, devastated the livestock farming industries. As a result, the prices of eggs and egg products had skyrocketed, and the event was reported by the media with heavy emphasis. The purpose of this study was to investigate the correlation between the egg price fluctuation and the keyword changes in online news articles reflecting social issues. To this end, we analyzed 682 cases of AI-related online news articles for fourteen weeks from November 2016 in South Korea. The results of this study are expected to contribute to understanding the relationship between the actual price of eggs and the keywords from news articles related to social issues.

• Korean Journal of Poultry Science
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• v.47 no.1
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• pp.9-19
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• 2020

Avian influenza (AI) viruses are highly contagious viruses that infect many bird species and are zoonotic. Ducks are resistant to the deadly and highly pathogenic avian influenza virus (HPAIV) and remain asymptomatic to the low pathogenic avian influenza virus (LPAIV). In this study, we identified common differentially expressed genes (DEGs) after a reanalysis of previous transcriptomic data for the HPAIV and LPAIV infected duck lung cells. Microarray datasets from a previous study were reanalyzed to identify common target genes from DEGs and their biological functions. A total of 731 and 439 DEGs were identified in HPAIV- and LPAIV-infected duck lung cells, respectively. Of these, 227 genes were common to cells infected with both viruses, in which 193 genes were upregulated and 34 genes were downregulated. Functional annotation of common DEGs revealed that translation related gene ontology (GO) terms were enriched, including ribosome, protein metabolism, and gene expression. REACTOME analyses also identified pathways for protein and RNA metabolism as well as for tissue repair, including collagen biosynthesis and modification, suggesting that AIVs may evade the host defense system by suppressing host translation machinery or may be suppressed before being exported to the cytosol for translation. AIV infection also increased collagen synthesis, showing that tissue lesions by virus infection may be mediated by this pathway. Further studies should focus on these genes to clarify their roles in AIV pathogenesis and their possible use in AIV therapeutics.

• Monthly Duck's Village
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• s.204
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• pp.12-17
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• 2020

조류인플루엔자가 아니라 '오리인플루엔자'라고? 3년째 계속된 사육제한으로 어려움을 겪고 있는 오리산업이 코로나19 여파로 소비위축이라는 수렁에 빠져 안간힘을 쓰고 있는 이 때 망언이 터져나왔다. 사건의 발단은 이러하다. 환경부 산하 공공기관인 국립생태원의 김영준 동물관리연구실장이 5월 4일자 한겨레신문(애니멀피플) 인터뷰에서 세계동물보건기구(OIE)의 공식 용어인 '조류인플루엔자(Avian Influenza, AI)'를 부정한 것이다. 급기야 "오리가 AI의 숙주이기 때문에 명칭을 '오리인플루엔자'로 지어야 한다"는 김영준 실장의 망언이 나왔고, 이에 전국의 오리농가들은 분노했다.

• Proceedings of the Korea Society of Poultry Science Conference
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• 2004.05a
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• pp.77-87
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• 2004

가금인플루엔자(Avian Influenza : AI)는 닭, 칠면조 등의 조류에 인플루엔자 바이러스 A형에 속하는 인플루엔자 바이러스에 의하여 발생하는 임상형이 다양한 전염성 질병이다 임상증상은 매우 다양하여 가벼운 호흡기성 증상에서부터 100 ％ 폐사까지 범위가 넓으며 주로 감염된 숙주의 종류에 영향을 받으나 숙주의 나이, 동시감염 여부, 외부환경 등에 따라서도 달라질수 있다. (중략)