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Seven-Day Continuous Abstinence Rate from Smoking at 1, 2, or 3 Years after the Use of Varenicline

  • Kim, Jin Se;Jang, Ju Young;Park, Eun Hye;Lee, Joo Young;Gu, Kang Mo;Jung, Jae Woo;Choi, Jae Chol;Shin, Jong Wook;Park, In Won;Choi, Byoung Whui;Kim, Jae Yeol
    • Tuberculosis and Respiratory Diseases
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    • v.78 no.2
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    • pp.92-98
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    • 2015
  • Background: Varenicline, a selective partial agonist/antagonist of the ${\alpha}4{\beta}2$ nicotinic receptor, has proven effectiveness for smoking cessation by several randomized, controlled trials. Because few studies have evaluated the long-term efficacy of varenicline, we tried to evaluate the smoking status of varenicline users up to 3 years after the initial prescription of the drug. Methods: We interviewed varenicline users who were prescribed the drug from June 2007 to May 2010 by telephone, from June 2010 to May 2011. Results: One-hundred and thirty-three of 250 varenicline users (53.2%) were available for the survey. Seven-day continuous abstinence from smoking was adhered to by 17 of 39 respondents (43.6%) at 1 year, and 11 of 36 (30.6%) and 19 of 58 (32.8%) at 2 and 3 years since the first use of varenicline, respectively. Compared to current smokers, successful quitters were older (55.0 years vs. 49.9 years, p=0.01), had better compliance to the 12-week course (27.7 vs. 9.3%, p=0.01), and had taken varenicline longer (10.1 vs. 5.9 weeks, p=0.01). Fifty-four of 71 current smokers (76.1%) were willing to stop smoking in the near future. The preferred ways to cease smoking were will-power (48.1%), varenicline (25.9%), nicotine replacement therapy (11.1%), and others (14.9%). Conclusion: Smokers should be encouraged to stick to the proven way for recommended period of time for successful cessation of smoking.

A Study on the Economic Efficiency of Capital Market (자본시장(資本市場)의 경제적(經濟的) 효율성(效率性)에 관한 연구(硏究))

  • Nam, Soo-Hyun
    • The Korean Journal of Financial Management
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    • v.2 no.1
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    • pp.55-75
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    • 1986
  • This article is to analyse the economic efficiency of capital market, which plays a role of resource allocation in terms of financial claims such as stock and bond. It provides various contributions to the welfare theoretical aspects of modern capital market theory. The key feature that distinguishes the theory described here from traditional welfare theory is the presence of uncertainty. Securities has time dimensions and the state and outcome of the future are really uncertain. This problem resulting from this uncertainty can be solved by complete market, but it has a weak power to explain real stock market. Capital Market is faced with the uncertainity because it is a kind of incomplete market. Individuals and firms in capital market made their consumption-investment decision by their own criteria, i. e. the maximization of expected utility form intertemporal consumption and the maximization of the market value of firm. We noted that allocative decisions that had to be made in the economy could be naturally subdivided into two groups. One set of decisions concerned the allocation of first-period resources among consumption $C_i$, investment in risky firms $I_j$, and riskless investment M. The other decisions concern the distribution among individuals of income available in the second period $Y_i(\theta)$. Corresponing to this grouping, the theoretical analysis of efficiency has also been dichotomized. The optimality of the distribution of output in the second period is distributive efficiency" and the optimality of the allocation of first-period resources is 'the efficiency of investment'. We have found in the distributive efficiency that the conditions for attainability is the same as the conditions for market optimality. The necessary and sufficient conditions for attainability or market optimality is that (1) all utility functions are such that -$\frac{{U_i}^'(Y_i)}{{U_i}^"(Y_i)}={\mu}_i+{\lambda}Y_i$-linear risk tolerance function where the coefficients ${\mu}_i$ and $\lambda$ are independent of $Y_i$, and (2) there are homogeneous expectations, i. e. ${\Large f}_i(\theta)={\Large f}(\theta)$ for every i. On the other hand, the efficiency of investment has disagreement about optimal investment level. The investment level for market rule will not generally lead to Pareto-optimal allocation of investment. This suboptimality is caused by (1)the difference of Diamond's decomposable production function and mean-variance valuation model and (2) the selection of exelusive investment or competitive investment. In conclusion, this article has made an analysis of conditions and processes of Pareto-optimal allocation of resources in capital marker and tried to connect with significant issues in modern finance.

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A Study of a Heat Flux Mapping Procedure to Overcome the Limitation of Heat Flux Gauges in Fire Tests (화재실험시 열유속 센서 사용의 단점을 보완한 Heat Flux Mapping Procedure에 관한 연구)

  • Choi, Keum-Ran
    • Journal of the Korean Society of Safety
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    • v.20 no.4 s.72
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    • pp.171-179
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    • 2005
  • It is essential to understand the role of wall lining materials when they are exposed to a fire from an ignition source. Full-scale test methods permit an assessment of the performance of a wall lining material. Fire growth models have been developed due to the costly expense associated with full-scale testing. The models require heat flux maps from the ignition burner flame as input data. Work to date was impeded by a lack of detailed spatial characterization of the heat flux maps due to the use of limited instrumentation. To increase the power of fire modeling, accurate and detailed heat flux maps from the ignition burner are essential. High level spatial resolution for surface temperature can be provided from an infrared camera. The objective of this study was to develop a heat flux mapping procedure for a room test burner flame to a wall configuration with surface temperature information taken from an infrared camera. A prototype experiment was performed using the ISO 9705 test burner to demonstrate the developed heat flux mapping procedure. The results of the experiment allow the heat flux and spatial resolutions of the method to be determined and compared to the methods currently available.

Evaluation of Waterway Dredging Work using Spud Dredge Process Management System (스퍼드 준설선 공정관리시스템을 이용한 항로준설작업의 평가)

  • Lee Joong-Woo;Jeong Dae-Deuk;Cho Jueng-Eon;Kim Ju-Young;Oh Dong-Hoon
    • Journal of Navigation and Port Research
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    • v.29 no.5 s.101
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    • pp.395-402
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    • 2005
  • The most important point when we engage on waterway dredging work is supplying safe navigational passage to the vessels underway by narrowing dredge work area and removing submerged dangers. In order to meet this end it is necessary to use auxiliary equipment for shifting actively and mooring and adopt automation of dredging work by integrating information on real time position, dredging depth, and work information. The dredger with a spud control system in this study, by the way, is able to employed on continuous dredging work with the narrowest working area allowing wide and safe passages to vessels underway, by moving the dredger to the working zone with the spud controlled automatically. Furthermore, it has been improved definitely compared with the existing dredging process management system such that it shows the track of spud and working depth on the electronic navigation chart of window, together with the final outcome of dredging work. The test dredging work at the entrance of Busan North Port for system evaluation showed that actual working time available was twice of the one by the existing anchor system, and that it reduced $38\%$ of time for preparation work and one man power.

Validity and Expected Effect of International Marketing Cooperative for Korean Animation (애니메이션 해외 배급 활성화를 위한 마케팅 협동조합 도입의 타당성 연구)

  • Kim, Young Jae
    • Cartoon and Animation Studies
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    • s.36
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    • pp.121-145
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    • 2014
  • Operating under the principle of user-benefit maximization and democratic user-control, cooperatives are being spot-lighted as a business model satisfying the various social, financial needs. In Korea, the Law of Cooperative was enacted as of December 2012, which has enabled the establishment of cooperatives in variety of industry fields. This study is to discuss the expected effect and validity of marketing cooperative as a solution for insufficient sales revenue in international distribution of Korean animation. The interviews with Korean animation studios found out the key problems of overseas distribution, which are; 1) lack of marketing expertise and weak organization, 2) lack of ancillary rights exploitation due to the deals based upon all rights package with the broadcasters who are not interested in ancillary business, 3) lack of localized marketing support in each territory. The solution for these problems takes large and long-term marketing investment and it is far beyond the capabilities of small Korean animation studios. Marketing cooperative can provide services not available otherwise such as in-depth market research which will help the improvement of international marketing expertise. Also. as the cooperative carries enough volume of animation catalogue, it can increase negotiation power satisfying the various needs of buyers. Also, it can provide the precise marketing support for each territory by integrating every process of value chain, from TV broadcasting, merchandising, and digital media platform. Above all, a clear benefit of marketing cooperative is that, because of its user-benefit and user-control principle, the principal-agent problem can be minimized while it maximizes the profit for member studios.

A Study on the Real-Time Oil-Spill Monitoring Technology (실시간 기름유출 모니터링 기술에 관한 연구)

  • Yeom, Woo-jung;Hong, Yeon-Chan
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.2
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    • pp.472-477
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    • 2017
  • Oil spills cause a lot of damage to the environment. Oil destroys the water environment and ecosystem in a very short period of time once they are contaminated by it, it takes a lot of time to recover from the contamination and the cleaning process is very difficult. Therefore, oil detectors are greatly needed as they can monitor any oil spills over the sea, rivers, and lakes. There are two kinds of technology available for detecting oil, viz. the contact and non-contact types. The former is based on the use of the conductivity, capacitance and microwaves, while the latter employs infrared, UV, laser, optic and radar technologies. As there are also various hurdles in the measuring of oil on water, such as the presence of waves, refraction of light, temperature and saltiness, it is imperative to select the right oil detector which is appropriate for the specific environment. In this study, a contact type oil detector is developed, which can be used in oil related industries, such as refineries, petrochemical companies, and power generation stations. The detector is made up of the sensor module, which floats on the water, and the controller which processes the signal coming from the sensor module and displays it. It is designed in such a way that the existence of oil is detected through the sensor and the change in the permittivity is observed to determine the volume and type of spilled oil.

Biological Leaching of Cu, Al, Zn, Ni, Co, Sn and Pb from Waste Electronic Scrap using Thiobacillus Ferrooxidans (廢電子스크랩에서 Thiobacillus ferrooxidans를 이용한 Cu, Al, Zn, Ni, Co, Sn 및 Pb의 浸出)

  • Ahn, Jae-Woo;Kim, Myeong-Woon;Jeong, Jin-Ki;Lee, Jae-Chun;Kim, Dong-Gin;Ahn, Jong-Gwan
    • Resources Recycling
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    • v.14 no.1
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    • pp.17-25
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    • 2005
  • In order to recover valuable metals from the waste electronic scrap, bioleaching of Cu, Zn, Al, Co, Ni, Sn and Pb was carried out using Thiobacillus ferrooxidans as a leaching microorganism in a shaking flask. In a preliminary study, to obtain the data on the leaching of Cu, Zn, Al, Co and Ni, the metal leaching was accomplished using metal powers instead of electronic scrap. The leaching percentaga of Cu, Zn, Co, Al and Ni powers was reduced with the increase of metal power concentration in solution. Below the metal concentration of 0.5 g/L, more than 85% of Cu, Co and Zn powers was leached out. At the electronic scrap concentration of 100 g/L, Thiobacillus ferrooxidans were able to leach more than 90% of the available Cu and Co while Al, Zn and Ni were able to leach less than 40%. Pb and Sn were not detected in the leachate. Pb was precipitated as PbSO$_4$, whereas Sn precipitated probably as SnO.

Effect of Band Spotty Fertilization on the Yield and Growth of Peanut(Arachis hypogaea L.) in Plastic Film Mulching Cultivation (비닐피복 땅콩 재배시 생육 및 수량에 미치는 국소시비 효과)

  • Yang, Chang-Hyu;Yoo, Chul-Hyun;Shin, Bok-woo;Cheong, Young-Keun;Kang, Seung-Won
    • Korean Journal of Soil Science and Fertilizer
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    • v.39 no.5
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    • pp.298-302
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    • 2006
  • This study was carried out to establish low-input fertilization and seeding technique using the simultaneous with seeding and fertilizer application machine and band spotty applicator which were manufactured for experiment during cultivation of mulching for peanut(Arachis hypogaea L.). The labor hour for seeding by simultaneous with seeding and fertilizing machine was appeared over 90% reduction effect compared with control plot($17.3hr\;10a^{-1}$). In band spotty fertilization plots, the emergence date was delayed about 4 days and the seedling stand rate was decreased 11~18% compared with control plot(man power). The content of total nitrogen of soil after experiment was increased while the contents of organic matter, available phosphate and exchangeable potassium were decreased than before experiment. The content of nitrogen forming nitrate was increased in band spotty fertilization(BSF) plots by increasing the amount of applied fertilizer from early growth stage till the middle growth stage. Growth rate was increased in band spotty fertilization plots and the absorbed amount of phosphate and potassium for peanut were increased in 70% band spotty fertilization plot compared with control plot. Yield of peanut was increased 70% in band spotty fertilization plot due to high pod kernel ratio and ripened pod rate compared with control plot($3,150kg\;ha^{-1}$). It was found that 70% band spotty fertilization was more effective as fertilization method to reduce both environmental pollution and chemical nitrogen fertilizer in plastic film mulching cultivation of peanut.

Power Enhance Effect on the Hybrid Cell Based on Direct Current Nanogenerator and an Organic Photovoltaic Device

  • Yun, Gyu-Cheol;Sin, Gyeong-Sik;Lee, Geun-Yeong;Lee, Ju-Hyeok;Kim, Sang-U
    • Proceedings of the Korean Vacuum Society Conference
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    • 2013.08a
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    • pp.298-298
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    • 2013
  • Finding renewable and clean energy resources is essential research to solve global warming and depletion of fossil fuels in modern society. Recently, complex harvesting of energy from multiple sources is available in our living environments using a single device has become highly desirable, representing a new trend in energy technologies. We report that when simultaneously driving the fusion and composite cells of two or more types, it is possible to make an affect the other cells to obtain a greater synergistic effect. To understand the coupling effect of photovoltaic and piezoelectric device, we fabricate the serially integrated hybrid cell (s-HC) based on organic solar cell (OSC) and piezoelectric nanogenerator (PNG). The size of increased voltage peaks when OSC and PNG are working on is larger than the case when only PNG is working. This voltage difference is the Voc change of OSC, not the voltage change of PNG and current density difference between these two cases is manifested more clearly. When the OSC and PNG are working in s-HC at the same time, piezoelectric potential (VPNG) is generated in ZnO and theoretical total voltage is sum of voltage of an OSC (VOSC) and VPNG. However, electrons from OSC are influenced by piezoelectric potential in ZnO and current loss of OSC in whole circuit decreases. As a result, VOSC increases temporarily. Current shows the similar behavior. PNG acts a resistance in the whole circuit and current loss occurs when the electrons from OSC pass through the PNG. But piezoelectric potential recover current loss and decrease the resistance of PNG. Our PNG can maintain piezoelectric potential when the strain is held owing to the LDH layer while general PNG cannot maintain piezoelectric potential. During the section that strain is held, voltage enhancement effect is maintained and same effect appeared even turn off the light. Actually at this time, electrons in ZnO nanosheets move to LDH and trapped by the positive charges in this layer. After this strain is held, piezoelectric potential of ZnO nanosheets is disappeared but potential difference which is developed by negative charge dominant LDH layer is remained. This potential acts similar role like piezoelectric potential in ZnO. Electrons from the OSC also are influenced by this potential and the more current flows.

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The Realization on GAS Sensor Module for Inteligent Wireless Communication (지능형 무선통신용 가스 센서 모듈 구현)

  • Kim, Hyo-Chan;Weon, Young-Su;Cho, Hyung-Rae
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.11 no.6
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    • pp.123-132
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    • 2012
  • Gas sensors has been used very differently that depending on following purposes; Automotive (exhaust gas, fuel mixture gas, oxygen, particulates), agriculture / food industry (fresh, stored, CO2, humidity, NH3, nitrogen oxide gas, organic gas, toxic gas emitted from pesticides and insecticides), industrial / medical (chemical gas, hydrogen, oxygen and toxic gases), military (chemical weapon), environmental measurements (CO and other air pollution consisting of sulfur and nitrogen gas), residential (LNG, LPG, butane, indoor air, humidity). The types of industrial toxic substances are known about 700 species and many of these exist in gaseous form under normal conditions. he multi-gas detection sensors will be developed for casualties that detect the most important and find easy three kinds of gases in marine plant; carbon dioxide(CO2), carbon(CO), ammonia(NH3). Package block consists of gas sensing device minor ingredient, rf front end, zigbee chip. Develope interworking technology between the sensor and zigbee chip inside a package. Conduct a performance test through test jig about prototype zigbee sensor module with rf output power and unwanted emission test. This research task available early address when poisonous gas leaked from large industrial site and contribution for workers' safety at the enclosed space.