• Journal of Auto-vehicle Safety Association
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• v.6 no.1
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• pp.5-9
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• 2014

Over the past ten years, since the introduction of the side crash test regulation in Europe, much research work has been performed internationally to develop new and modified test procedures to improve the level of occupant protection offered by vehicles in side crash test. This research has been co-ordinated and finally contributed to development of an AE-MDB(Advanced European Moving Deformable Barrier) and WorldSID (Worldwide Side Impact Dummy). EuroNCAP(European New Car Assessment Program) has the plan to conduct AE-MDB side crash test using WorldSID from 2015 by replacing Progressive MDB and EuroSID II. Automobile manufacturers need to respond to these changes closely. This paper is to find dominant control factor and analyze it of WorldSID 50%ile dummy injury through AE-MDB side crash test by predicting best and worst condition. And control factors will be validated within EuroNCAP regulations. This paper is analyzed by DFSS(Design for six sigma) which contains 5 control factors and is evaluated by ANOVA with the data as a result of LS-DYNA analysis correlated with crash pulse from 50 kph AE-MDB side crash test using WorldSID 50%ile dummy.

• Journal of Korean Society of Transportation
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• v.32 no.3
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• pp.207-217
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• 2014

Many a number of policies have been tried to reduce auto accidents so far, but it is obvious that further studies are still needed to find a more fundamental and multi-dimensional preventive measure with effect. The National Mental Health Statistics shows that the most profound forms of negative emotions, that is, depression and anxiety, have been increasing, but studies on such a topic are scarce to find. Therefore, we conducted a structural analysis between the negative emotions, including depression and anxiety, of drivers and their driving behaviors using a Structural Equation Modeling(SEM) technique. The review of past literature and studies indicated that not all of human emotions manifest themselves as the ultimate behaviors because they go through emotion regulation Strategies. For this reason, the purpose of this study was set to analyze the structural model developed in this study reflecting the emotion regulation strategies. The result of our analysis showed that the driver's negative emotion had a more significant influence on dangerous driving behaviors than safe ones, and especially, the expressive suppression strategy was found to be the highest factor. Also, the total effect analysis with the negative emotional factors showed that expressive suppression had more significant influence compared to that of cognitive reappraisal. The implication of this study might provide a better understanding on driving behaviors of the drivers and could be used as a fundamental study for future policy development to reduce traffic accidents.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.2
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• pp.457-463
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• 2015

The pathogenesis of mantle cell lymphoma, a special subtype of lymphoma that is invasive and indolent and has a median survival of 3 to 4 years, is still partially unexplained. Much research about genes and miRNAs has been conducted in recent years, but interactions and regulatory relations of genetic elements which may play a vital role in genesis of MCL have attracted only limited attention. The present study concentrated on regulatory relations about genes and miRNAs contributing to MCL pathogenesis. Numerous experimentally validated raw data were organized into three topology networks, comprising differentially expressed, associated and global examples. Comparison of similarities and dissimilarities of the three regulating networks, paired with the analysis of the interactions between pairs of elements in every network, revealed that the differentially expressed network illuminated the carcinogenicity mechanism of MCL and the related network further described the regulatory relations involved, including prevention, diagnosis, development and therapy. Three kinds of regulatory relations for host genes including miRNAs, miRNAs targeting genes and genes regulating miRNAs were concluded macroscopically. Regulation of the differentially expressed miRNAs was also analyzed, in terms of abnormal gene expression affecting the MCL pathogenesis. Special regulatory relations were uncovered. For example, auto-regulatory loops were found in the three topology networks, key pathways of the nodes being highlighted. The present study focused on a novel point of view revealing important influencing factors for MCL pathogenesis.

• BMB Reports
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• v.32 no.3
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• pp.215-225
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• 1999

Phytochromes (with gene family members phyA, B, C, D, and E) are a wavelength-dependent light sensor or switch for gene regulation that underscore a number of photo responsive developmental and morphogenic processes in plants. Recently, phytochrome-like pigment proteins have also been discovered in prokaryotes, possibly functioning as an auto-phosphorylating/phosphate-relaying two-component signaling system (Yeh et al., 1997). Phytochromes are photochromically convertible between the light sensing Pr and regulatory active Pfr forms. Red light converts Pr to Pfr, the latter having a "switch-on" conformation. The Pfr form triggers signal transduction pathways to the downstream responses including the expression of photosynthetic and other growth-regulating genes. The components involved in and the molecular mechanisms of the light signal transduction pathways are largely unknown, although G-proteins, protein kinases, and secondary messengers such as $Ca^{2+}$ ions and cGMP are implicated. The 124-127 kDa phytochromes form homodimeric structures. The N-terminal half contains the tetrapyrrolic phytochromobilin for red/far-red light absorption. The C-terminal half includes both a dimerization motif and regulatory box where the red light signal perceived by the chromophore-domain is recognized and transduced to initiate the signal transduction cascade. A working model for the inter-domain signal communication within the phytochrome molecule is proposed in this Review.

• Transactions of the Korean Society of Automotive Engineers
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• v.15 no.6
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• pp.170-176
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• 2007

It is time to prepare the phaseout of R134a, the current refrigerant, in automotive air conditioning system because the EC deadline has been coming with new platform vehicles in 2011 and all vehicles by 2017. Until now a high-pressure carbon dioxide($CO_2$) system is the leading replacement of R134a in European auto-makers but there is no firm agreement in the world automotive market. Recently three new fluids have been announced as the possibilities from Honeywell, DuPont and INEOS Fluor. The new alternative refrigerant should meet the requirements like non flammable, non toxic, no ozone depletion effect and low GWP(under 150 to meet EC regulation). The objectives of this paper are to review the fluid H from Honeywell, the more possible alternative refrigerant in 3 new fluids, compare the properties of R134a & fluid H and see the possibility as a replacement of R134a. In this experimental paper we ran and reviewed the cooling performance data in the bench system, the vehicle and the field test. We found the possibility of fluid H system to meet the R134a system performance with some hardware modifications but agreed that it is still needed to study about the long term safety, environmental effects, material compatibilities and so on.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.10 no.12
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• pp.3622-3625
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• 2009

This study develops a variable structure controller using the time-varying nonlinear sliding surface instead of the fixed sliding surface, which has been the robustness against parameter variations and extraneous disturbance during the reaching phase. By appling TS algorithm to the regulation of the rionlinear sliding surface, the reaching time of the system trajectory is faster than the fixed method. This proposed scheme has better performance than the conventional method in reaching time, parameter variation and extraneous disturbance. The effectiveness of the proposed control scheme is verified by simulation results.

• Journal of the Korean Society of Safety
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• v.27 no.4
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• pp.90-95
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• 2012

To prevent similar accidents with the basis of industrial accidents already occurred in industrial plants, it would be possible only after true causes are grasped. Unfortunately, however, most accident investigation carried out with the basis of legal regulation failed to grasp them so that similar accidents have been repeated without cease. This research aimed to find out differences between results from conventional accident investigation and those from human error analysis, and to draw out effective and practical counter-plans against industrial accidents occurred repeatedly in an autoglass manufacturing company. As for analysis, about 110 accident cases that occurred for last 7 years were collected, and by adopting the Comprehensive Human Error Analysis Technique developed by the previous researchers, not direct causes but basic fundamental causes that might induce workers to human errors were sought. In consequence, the result showed that facility factors or environmental factors such as improper layout, mistakes in engineering design, and malfunction of interlock system were authentic major accident causes as opposed to managerial factors such as personal carelessness or failure to wearing personal protective equipments, and/or improper work methods.

• Journal of the Korea Society of Computer and Information
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• v.12 no.6
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• pp.105-113
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• 2007

A gene regulatory network is a network of genes representing how genes influence the activities of other genes. Nowadays from microarray experiments, a large number of measurements on the expression levels of genes are available. One of typical data is the so-called "steady-state model" data measuring the expression levels of other genes after knocking out a particular gene. This paper shows how to reverse engineer a parsimonious gene regulatory network, using these measurement data. Our model considers auto-regulation, which forms a cycle in a genetic network. We also model repressor and enhancer roles of genes. which are not considered in previous known methods.

• Journal of Soil and Groundwater Environment
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• v.15 no.6
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• pp.1-8
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• 2010

The groundwater level distribution and characteristics of responses to rainfall were examined in the Haean basin of Yangu that has a single stream exit to the east. The groundwater levels showed a circular or elliptical distribution converging the center of the basin with different hydraulic gradients in the north and south regions. The waterlevel elevations exhibited a perfect correlation with topographic elevation ($r^2=0.99$) while the depth to water showed a rather weak correlation ($r^2=0.49$). The water table fluctuation (WTF) method yielded recharge ratios of 6.1~12.65% ($S_y=0.02$) and 15.2~28.5% ($S_y=0.05$). The waterlevels of HG3 well, which is much proximal to a stream, were weakly auto-correlated but they were highly sensitive to direct infiltration from the rainfall event. The shorter regulation times of the HG3 represented a quicker dissipation of the input stress (rainfall).

• Journal of the Korean Society of Propulsion Engineers
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• v.16 no.6
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• pp.85-91
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• 2012

This paper describes the results of study on reaction of insensitive igniter in which a pyrosensor is automatically sensing the rate of risk of fire or explosion of solid rocket motor exposed to an unexpected fire and makes the rocket motor burn itself safely. The Slow Cook Off(SCO) test following the regulation of MIL-STD-2105D was carried out with a rocket motor loaded with HTPB propellant, in which a thermal pyrosensor igniter was installed. The auto-ignition temperature measured was approximately $140^{\circ}C$ and it corresponded to Type V(Burning) reaction in SCO test, while the temperature by Kissinger equation was calculated to be $165.5^{\circ}C$.