• BMB Reports
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• v.35 no.6
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• pp.537-546
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• 2002

NF-${\kappa}B$/Rel transcription factor family participates in diverse biological processes including embryo development, hematopoiesis, immune regulation, as well as neuronal functions. In this review, the NF-${\kappa}B$/Rel signal transduction pathways and their important roles in the regulation of immune system will be discussed. NF-${\kappa}B$/Rel members execute distinct functions in multiple immune cell types via the regulation of target genes essential for cell proliferation, survival, effector functions, cell trafficking and communication, as well as the formation of lymphoid architecture. Consequently, proper activation of NF-${\kappa}B$/Rel during immune responses to allergens, auto-antigens, allo-antigens, and pathogenic infection is crucial for the integrity of host innate and adaptive immunity.

• BMB Reports
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• v.46 no.6
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• pp.289-294
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• 2013

To maintain cellular homeostasis against the demands of the extracellular environment, a precise regulation of kinases and phosphatases is essential. In cell cycle regulation mechanisms, activation of the cyclin-dependent kinase (CDK1) and cyclin B complex (CDK1:cyclin B) causes a remarkable change in protein phosphorylation. Activation of CDK1:cyclin B is regulated by two auto-amplification loops-CDK1:cyclin B activates Cdc25, its own activating phosphatase, and inhibits Wee1, its own inhibiting kinase. Recent biological evidence has revealed that the inhibition of its counteracting phosphatase activity also occurs, and it is parallel to CDK1:cyclin B activation during mitosis. Phosphatase regulation of mitotic kinases and their substrates is essential to ensure that the progression of the cell cycle is ordered. Outlining how the mutual control of kinases and phosphatases governs the localization and timing of cell division will give us a new understanding about cell cycle regulation.

• Proceedings of the KIPE Conference
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• 2018.07a
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• pp.522-524
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• 2018

A New Direct AC LED Driver has been proposed for wide output power range and precise constant current regulation using an advanced auto commutation topology. The conventional shunt regulation method provides a stepped input current shape by fixed regulation references in the linear regulator of the each channel, which results in poor current regulation and high THD. The conventional method needs to assign a linear regulator in each LED channel so that the number of linear regulator increases when extending the number of channels especially at high power application. The proposed regulation method can drive multiple switches to regulate each LED channel current by a single amplifier with sinusoidal reference so that large number of LED channel can be simply extended with less BOM cost and low THD is obtained with the accurate current regulation thanks to the sinusoidal input current control in the closed loop control. To confirm the validity of the proposed circuit, theoretical analysis and experimental results from a 20-W LED driver prototype are presented.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.21 no.3
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• pp.225-232
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• 2008

Overload vehicles operate damage to road, bridge, and then increasing in maintenance and repair cost because structures are reduced durability. The existing regulation systems have many problems and need coping measure. Therefore, this paper organized Ubiquitous sensor network system for development of intelligent auto overload vehicle regulation system about high speed vehicles, also axial load WIM sensor was selected by indoor experiment through wireless protocol. And we examined possibility U-load auto overload vehicle regulation system through experiment of the transmission and reception distance. If this system will apply to road and bridge, might be effective for economy and convenience through establishment of U-IT system. And high speed vehicle that was amalgamate IT technology and existing overload regulation problems, also tested wireless sensor for USN organization. This experiment aim to organize system interface for user through perfection man-less, wireless system of Internal/External Network from high speed WIN sensor with USN organization. Accordingly, it is necessary experimentation through Test Bed for constitution External network and application of actually regulations using WCDMA/HSDPA.

• Journal of Auto-vehicle Safety Association
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• v.9 no.3
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• pp.13-18
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• 2017

Since 2015, Euro-NCAP and C-NCAP have enhanced regulation on submarine of rear female passenger. This submarine regulation is a big obstacle to achieve the highest level crash performance. So the objective of this study is to develop new technical way to protect rear female passenger against submarine. In this study, we figured out how design factors of seatbelt affect submarine of rear female passenger by sled test. And we verified that rear passenger submarine can be improved by increasing intersection angle of seatbelt anchor and rotation amount of seatbelt buckle. Based on these results, this paper proposes a new invention of seatbelt buckle and anchor that can improve rear passenger submarine. One is seatbelt buckle that can be detached from stopper to prevent rotation and the other is seatbelt anchor that can be changed the structure so as to incline forward during crash. Finally we proved that submarine of rear female passenger can be improved by the effectiveness of new inventions.

• Proceedings of the KIPE Conference
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• 2005.07a
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• pp.317-320
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• 2005

본 논문은 멀티-레벨 H-bridge 인버터에서 입력전압 변동에 따른 AVR(Auto Voltage Regulation)기능을 적용 그 타당성을 제안하였다. 기존의 범용 인버터에서 (V/F)로 구동되는 전동기 시스템에 있어서 인버터에 공급되는 입력 전압은 출력 주파수에 따라 출력 전압 비율을 일정하게 하고 기동에 필요한 전압을 더하여 출력하는 방식이다. 집중 제어 방식의 멀티-레벨 H-bridge 인버터에서는 Cell의 DC-Link 전압을 Master에서 받아들여서 각각의 Cell에 기준 전압값을 지령하게 된다. 그러므로 입력 전압 변동에 따른 DC-Link 전압의 변동이 발생하게 되면 상전압 Unbalance 가 발생하게 되어 부하가 원하는 출력 전압을 낼 수가 없게 된다. 또한 각각의 Cell을 제어하는 Master 제어기가 가지고 있는 문제점을 보완하여 각각의 Cell 제어기 스스로가 AVR을 수행하는 좀더 나은 방법을 제안하였다.

• Journal of Auto-vehicle Safety Association
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• v.13 no.4
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• pp.66-72
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• 2021

This study was initiated to improve of the defect investigation method using event data recorders (EDR) and suggested a solution through the regulation and system analysis of EDR. The EDR data has been used for various purposes such as the vehicle defect investigation and the traffic accident investigation. However the EDR regulation has not been updated since the implementation in 2012. "Trigger Threshold" can be used to analyze a single accident such as the frontal crash, the side crash, and the rollover. In the case of a complex accident in which a rollover accident and a crash accident occur simultaneously, it is difficult to analyze a complex accident due to current "Trigger Threshold". This study proposed the method of separating the "Trigger Threshold" into a crash accident and a rollover accident so that accidents can be analyzed using the EDR data even when a complex accident occurs. In addition, it proposed the improvement method to quickly use the data of EDR in accident reconstruction software.

• Journal of Auto-vehicle Safety Association
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• v.13 no.1
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• pp.51-56
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• 2021

As hydrogen is classified as an eco-friendly fuel, vehicles using hydrogen fuel are being developed worldwide. Vehicle fuel hydrogen is stored in cylinders at 70 MPa, so there is a high risk of explosion. Therefore, it is important to inspect hydrogen cylinders in used-vehicles. This study was conducted to improve the inspection method of the cylinders currently mounted on used-hydrogen buses. The inspection method is an image analysis method using a camera. Calcaulation algorithm was developed to quantitatively chech the amount of hydrogen leakage by the image method. As a result of adding a contact angle element to the calculation algorithm suggested by the GTR regulation and comparing it with the experimental data of the GTR regulation, the algorithm reliability was 94%, which secured similarity.

• Journal of Auto-vehicle Safety Association
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• v.13 no.2
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• pp.15-23
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• 2021

Even though the number of CO poisoning casualties caused by unintended idling for the vehicles equipped with keyless ignition systems is more than 70, the problem still remains unsolved and became social issue in the US, and Senates introduced the bill which urges NHSTA to make regulation for this accordingly. To meet market safety needs and the regulations, we decided to provide automatic shut-off system very soon. In this paper, we would like to describe how to validate vehicle shut-off timing including defining required tests and case selections considering vehicle condition, garage/room size and temperatures with several assumptions. We believe that safe implementation of the shut-off function is possible via this methodology and the results. As NHTSA must be interested in shut-off timing, the methodology can be enhanced and conclusions could be reflected highly in the future regulation in case we continue this study with NHTSA or any other 3-rd party institutes.

• Korean Journal of Culture and Social Issue
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• v.12 no.4
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• pp.77-99
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• 2006

The purpose of this study was to find out the effects of auto-mobile tinting upon driver's cognitive responses and behaviors through two laboratory experiments, a field experiment and a traffic accident data. The results of two laboratory experiments showed that there were higher false alarm responses under the conditions of 65%, 50%, 35% tinting level than thoses under the 100% level condition. It was also shown that the drivers who had bad sight made more missing responses than the drivers who had normal vision. The main results of the laboratory experiment were repliceted through both the field experiment and the survey research of car accidents. The results of this study were discussed in terms of the previous studies performed abroad. We strongly suggested 70% tinting level as a regulation standard for safe driving and the strategies for implementing the regulation rule.