• Asian-Australasian Journal of Animal Sciences
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• v.25 no.10
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• pp.1473-1480
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• 2012

The Galactose-${\alpha}1$,3-galactose (${\alpha}1$,3Gal) epitope is responsible for hyperacute rejection in pig-to-human xenotransplantation. Human decay-accelerating factor (hDAF) is a cell surface regulatory protein that serves as a complement inhibitor to protect self cells from complement attack. The generation of ${\alpha}1$,3-galactosyltransferase (GGTA1) knock-out pigs expressing DAF is a necessary step for their use as organ donors for humans. In this study, we established GGTA1 knock-out cell lines expressing DAF from pig ear fibroblasts for somatic cell nuclear transfer. hDAF expression was detected in hDAF knock-in heterozygous cells, but not in normal pig cells. Expression of the GGTA1 gene was lower in the knock-in heterozygous cell line compared to the normal pig cell. Knock-in heterozygous cells afforded more effective protection against cytotoxicity with human serum than with GGTA1 knock-out heterozygous and control cells. These cell lines may be used in the production of GGTA1 knock-out and DAF expression pigs for xenotransplantation.

• Journal of Advanced Marine Engineering and Technology
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• v.35 no.4
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• pp.475-482
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• 2011

This study, a basic study to improve aerodynamic characteristic of a wind blade, explored through CFD how much the lift to drag ratio improves according to the shape of groove formed on the surface of airfoil NACA0015. This study found out that the ratio improves by 8.7% when the ratio between boundary layer(${\delta}$) and the depth of groove(h), the ratio between the depth of groove(h) and the width of groove(d) and the ratio between the length(p) from one groove to the other and the width of groove are 1.1, 0.1 and 1.2 respectively. The number of grooves is two. It was also confirmed that the improvement of the lift to drag ratio is maintained after certain angle of attack.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.35 no.10
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• pp.927-933
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• 2007

Heat transfer characteristic near a sharp fin was studied in a supersonic flow. Mach number and the Reynolds number were 3 and $5{\times}10^7$ respectively. Infra-red thermography was used to obtain the variation of surface heat transfer coefficient distribution. The angles of attack were ranged from $12.5^{\circ}$ to $20^{\circ}$ and the numerical analysis and the oil flow method were conducted to understand flow fields near a sharp fin.

• Journal of the Korean Society of Industry Convergence
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• v.10 no.4
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• pp.207-211
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• 2007

The durable lifetime of RC structures is shortened by various reasons, which are the generation of cracks in construction and service term, the exterior deterioration according to climatic condition, the surface damage due to chloride attack and the corrosion of reinforced bars. The durability of concrete structures is nevertheless able to be increased by the method and the material of reinforcement and repair. The epoxy resin is widely used for reinforment and repair of concrete because of the superiority in mechanical property, adhesive property, abrasion resistance, impact resistance and chemical resistance. The epoxy cement mortar with hardening agent has a lot of disadvantages that are troublesome mixing work, weakened weatherability and high cost for hardening agent. In this study, the mix proportion of mortar is presented just only with epoxy resin and some admixtures, and the test result of mortar without hardening agent shows the higher strength than the mortar with hardening agent. In the mix proportion, the weight of epoxy resin must be less than 15% of the unit weight of cement, and 10% of unit weight of cement is adequate for the weight of admixtures.

• The Journal of Korean Medicine
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• v.29 no.2
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• pp.21-31
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• 2008

Backgrounds: Singihwan is used "to strengthen inborn energy" and we suspected a protective effect on brain neuron cells. Objectives: The aim of this study was to evaluate the effects of Singihwan (SGH) on traumatic brain injury-induced delayed apoptosis in rat hippocampal dentate gyrus. Methods: For a surgical induction of traumatic brain injury (TBI), a 5 mm diameter stainless rod was used to make traumatic attack from the surface of the brain used by an impactor. The protective effect of the aqueous extract of SGH against TBI in the rat hippocampal dentate gyrus was investigated by using step-down avoidance task, terminal deoxynucleotidyl transferase (TdT)-mediated dUTP nick end labeling (TUNEL) assay, Bax immunohistochemistry, and 5-bromo-2'-deoxyuridine (BrdU) immunohistochemistry. Results: The aqueous extract of SGH suppressed the TBI-induced increase in apoptosis and cell proliferation in the hippocampal dentate gyrus. Conclusions: It is possible that the aqueous extract of SGH has a neuroprotective effect on TBI-induced neuronal cell death.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.39C no.12
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• pp.1243-1249
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• 2014

The naval mine is the explosives that are installed in the water in order to attack surface ships or submarines. So mine warfare is a very important component of naval operations. In this paper, first, understanding of the general concept about mine warfare. Second, introduce the mine hunting progress and mine sweeping progress. And then, suggest the system design method of mine counter measure warfare using several functions. The functions are mine area detection algorithm for side scan sonar image using Adaboost algorithm, and calculation to mine hunting progress rate and mine sweeping progress rate. And techniques that lead the mine disposal vehicle(MDV) to mine.

• International Journal of Highway Engineering
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• v.17 no.2
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• pp.47-53
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• 2015

PURPOSES: The scaling of a concrete surface caused by the combined effects of frost and de-icing salts is one of the main reasons for the need to repair transportation infrastructures in cold-climate regions. This study describes the results of attempts to determine the scaling resistance of concrete incorporating mineral admixtures such as fly ash, GGBFS, and silica fume, and subjected to the actions of frost and salt. METHODS : Conventionally, to evaluate the fundamental properties of concrete, flexural and compressive strength measurements are regularly performed. Based on the ASTM C 672 standard, concrete is subjected to 2%, 4%, and 8% $CaCl_2$ salt solutions along with repeated sets of 50 freeze/thaw cycles, and the scaling resistance was evaluated based on the mass of the scale and a visual examination. RESULTS : It was observed that silica fume is very effective in enhancing the scaling resistance of concrete. Meanwhile, concrete incorporating GGBFS exhibited poor resistance to scaling, especially in the first ten freeze/thaw cycles. However, fly ash concrete generally exhibited the maximum amount of damage as a result of the frost-salt attack, regardless of the concentrations of the solutions. CONCLUSIONS: It can be concluded that the scaling resistance of concrete is highly dependent on the type of the mineral admixture used in the concrete. Therefore, to provide a durable concrete pavement for use in cold-climate regions, the selection of a suitable binder is essential.

• Journal of the Speleological Society of Korea
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• no.85
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• pp.28-34
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• 2008

For trying to frontal attack of new solution by fusion of technical tasks and conditions with it's solving methods of the essential tasks of marine resource development and environmental conservation in addition with elements of electronic high-technologies, the magnetic oil spill adsorbent of Mag-Sorbent* has been prepared and proposed to dispose oil spill from the marine disaster for preventing oil pollution by using them and their system with sequentially circular collection of oil spill mag-sorbent powder and fabrics on the electronic equipment like as barge robot for the scheme of sustainable development of environment-friendly technology. Because of recent marine accident occurred at Tae-An cost and earthquake in Sichuan province were very large scale accident of disaster to prevent and manage of them. So, it was verified from the experiment of electronic demonstrator that the skimmer system of oil spill mag-sorbent powder and fabrics prepared was very effective and useful technique to collect oil spill samples on the water surface specially at the closed space of underground cave. At this point, the barge-based electronic remote control was very useful system operating easily on the marine fields but also water level at the small pool to skim it with the environment-friendly system of the disposing marine disaster and preventing oil pollution using magnetic adsorbents of Mag-Sorbent*.

• Journal of Welding and Joining
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• v.8 no.4
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• pp.27-34
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• 1990

Integranular corrosion behaviors of KAL (Knife Line Attack) and mechanical properties such as tensile and creep rupture were investigated for the tube material used for nearly 20 years under the condition of 463.deg. C and 28 $kg/cm^2$. Based and weld metal were austenitic stainless steel AISI 321 containing Ti, AISI 347 containing Nb, respectively. KLA is a kind of the intergranular corrosion which often occurs just near the HAZ (heat affected zone) of AISI 321 and AISI 347 stainless steel due to the grain boundary sensitization. In KLA zone, intergranular corrosion crack has propagated outwards from the inner surface and carbides of white and narrow band type assuming as (Cr, Fe) carbide were confirmed. All the delta-ferrite formed in the weld metal during weld solidification has been transformed into sigma-phase since delta-ferrte was exposed for 20 years at 463.deg. C. Elongation was very low at the range from room temperature to 600.deg. C and it was confirmed that creep-rupture properties were not consideralbly affected.

• The Korean Journal of Ceramics
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• v.1 no.2
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• pp.86-90
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• 1995

Theoretical predictions for thermodynamically stable phases which formed when alkali(sodium and potassium) vapors reacted with alumina-chromia refractories under coal gasifying atmosphere were confirmed experimentally using a laboratory-scale coal gasifying reaction system and a commercial alumina-chromia refractory using SEM, XRD, and EDAX. Alkali concentration profiles in the refractory as a function of time were also determined. The results showed that the compounds that formed were $X_2O{\cdot}Al_2O_3, X_2O{\cdot}Cr_2O_3, X_2O{\cdot}5Al_2O_3, X_2O{\cdot}7Al_2O_3, X_2O{\cdot}11Al_2O_3(X=Na^+ \;or\; K^+)$, depending upon the alkali concentration and time of exposure at high temperatures. The presence of sulfur in gasifying atmospheres did not appear to affect the alkali reaction produces. Alkali pentration into the alumina-chromia refractory was deep and the formation of the $Na_2O{\cdot}Al_2O_3/K_2O{\cdot}Al_2O_3$ compunds resulted in the serious deformation of the refractory due to the large volume expansion at the reaction surface. The hot face of the alumina-chromia refractory in service under an alkali environment is prone to failure by alkali attack.