• 한국진공학회:학술대회논문집
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• 한국진공학회 2016년도 제50회 동계 정기학술대회 초록집
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• pp.77-77
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• 2016

Thin films synthesized by plasma processes have been widely applied in a variety of industrial sectors. The structure control of thin film is one of prime factor in most of these applications. It is well known that the structure of this film is closely associated with plasma parameters and species of plasma which are electrons, ions, radical and neutrals in plasma processes. However the precise control of structure by plasma process is still limited due to inherent complexity, reproducibility and control problems in practical implementation of plasma processing. Therefore the study on the fundamental physical properties that govern the plasmas becomes more crucial for molecular scale control of film structure and corresponding properties for new generation nano scale film materials development and application. The thin films are formed through nucleation and growth stages during thin film depostion. Such stages involve adsorption, surface diffusion, chemical binding and other atomic processes at surfaces. This requires identification, determination and quantification of the surface activity of the species in the plasma. Specifically, the ions and neutrals have kinetic energies ranging from ~ thermal up to tens of eV, which are generated by electron impact of the polyatomic precursor, gas phase reaction, and interactions with the substrate and reactor walls. The present work highlights these aspects for the controlled and low-temperature plasma enhanced chemical vapour disposition (PECVD) of Si-based films like crystalline Si (c-Si), Si-quantum dot, and sputtered crystalline C by the design and control of radicals, plasmas and the deposition energy. Additionally, there is growing demand on the low-temperature deposition process with low hydrogen content by PECVD. The deposition temperature can be reduced significantly by utilizing alternative plasma concepts to lower the reaction activation energy. Evolution in this area continues and has recently produced solutions by increasing the plasma excitation frequency from radio frequency to ultra high frequency (UHF) and in the range of microwave. In this sense, the necessity of dedicated experimental studies, diagnostics and computer modelling of process plasmas to quantify the effect of the unique chemistry and structure of the growing film by radical and plasma control is realized. Different low-temperature PECVD processes using RF, UHF, and RF/UHF hybrid plasmas along with magnetron sputtering plasmas are investigated using numerous diagnostics and film analysis tools. The broad outlook of this work also outlines some of the 'Grand Scientific Challenges' to which significant contributions from plasma nanoscience-related research can be foreseen.

• 자원환경지질
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• 제26권3호
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• pp.403-420
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• 1993

The Cretaceous Kyongsang Basin is known to be composed of several tectonic blocks (or subbasins) with each distinct stratigraphic succession. The study area represents a major part of one of these blocks, i. e. the $\check{U}is\check{o}ng$ block. The area is charaterized by a suite of WNW-trending sinistral strike-slip faults as well as a number of ring faults. A total of 292 independently oriented core samples were drilled from 23 sites, covering virtually all the formations of the Cretaceous $Ky\check{o}ngsang$ Supergroup. Alternating field and thermal demagnetization experiments were conducted to reveal the primary magnetization. Due to the homoclinal nature of the strata in the area, it was not possible to make use of the conventional fold test It is, however, believed that the primary remanent components have been obtained from the majority of the formations, considering the similarity of the palaeomagnetic pole positions with those of contemporary strata of other blocks and the existence of antiparallel reversed remanence. It was found neither any significant difference in magnetic declination on each side of the strike-slip faults nor systematic change of magnetic declination with distance from the fault-line. This does not support such a block rotation hypothesis associated with the strike-slip faulting in the area as alleged by some authors. The samples from the outcrops on or near the fault-lines were severely overprinted by the recent magnetic fields regardless of age and lithology. Epithermal Au-Ag-Cu-Pb-Zn mineralizations are known along some fault lines in the area. It is interpreted that these two facts are closely related with fluid circulations along the fracture zones caused by fault activities. In regard to the age of the strata as deduced from the magnetostratigraphic consideration, the $Ch\check{o}mgok$ formation and the lower strata should be older than Barremian or 124 Ma. The age of volcanics of the $Yuch^{\prime}\check{o}n$ Group sampled in this study should be younger than Campanian or 83 Ma.

• Asian Pacific Journal of Cancer Prevention
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• 제15권22호
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• pp.9773-9779
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• 2014

Background: Colorectal cancer (CRC) is one of the prime causes of mortality around the globe, with a significantly rising incidence in the Middle East region in recent decades. Since detection of CRC in the early stages is an important issue, and also since to date there are no comprehensive epidemiologic studies depicting the Middle East region with special attention to the average risk group, further investigation is of significant necessity in this regard. Aim: Our aim was to investigate the prevalence of preneoplastic and neoplastic lesions of the colon in an average risk population. Materials and Methods: A total of 1,208 eligible asymptomatic, average- risk adults older than 40 years of age, referred to Firuzgar Hospotal in the years 2008-2012, were enrolled. They underwent colonoscopy screening and all polypoid lesions were removed and examined by an expert gastrointestinal pathologist. The lesions were classified by size, location, numbers and pathologic findings. Size of lesions was measured objectively by endoscopists. Results: The mean age of participants was $56.5{\pm}9.59$ and 51.6% were male. The overall polyp detection rate was 199/1208 (16.5 %), 26 subjects having non-neoplastic polyps, including hyperplastic lesions, and 173/1208 (14.3%) having neoplastic polyps, of which 26 (2.15%) were advanced neoplasms. The prevalence of colorectal neoplasia was more common among the 50-59 age group. Advanced adenoma was more frequent among the 60-69 age group. The majority of adenomas were detected in the distal colon, but a quarter of advanced adenomas were found in the proximal colon; advance age and male gender was associated with the presence of adenoma. Conclusions: It seems that CRC screening among average-risk population might be recommended in countries such as Iran. However, sigmioidoscopy alone would miss many colorectal adenomas. Furthermore, the 50-59 age group could be considered as an appropriate target population for this purpose in Iran.

• 동의생리병리학회지
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• 제23권5호
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• pp.1106-1115
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• 2009

Mori Ramulus has multiple applications in Korean traditional medicine prescription because it has antioxidant and anti-inflammatory effects by reducing macrophage activities. Yet, no studies on the anti-arthritic activity of EMR (extract of Mori Ramulus) have been reported in vitro and in vivo. Rheumatoid arthritis (RA) is a systemic autoimmune disease with chronic inflammation characterized by hyperplasia of synovial cells in affected joints, which ultimately leads to the destruction of cartilage and bone. Because collagen-induced arthritis (CIA) is similar to RA in pathological symptoms and immune reactions, there have been several reports concerning RA using CIA mouse model. Here, we investigated the effects of Mori Ramulus on RA using CIA mice. The importance of CD4+ Th1 cells in RA progress was previously indicated and studies further showed that Th17 cells play a prime role in severity of disease. Accordingly, the present study was focused on CIA associated with CD4+ Th1 cells and Th1 7 cells. DBA/1OlaHsd mice were immunized with bovine type II collagen (CII). After a second collagen immunization, mice were treated with EMR once a day for 4 weeks. The severity of arthritis within the paw joints was evaluated by histological assessment of cartilage destruction and pannus formation. Immune cells in peripheral blood mononuclear cells (PBMC), draining lymph node (DLN) and paw joints, cytokine production and gene expression were assessed from CIA mouse using ELISA, FACS and real-time PCR analysis. Administration of EMR significantly suppressed the progression of CIA and inhibited the production of TNF-$\alpha$, IL-6 and IL-17 in the serum. The erosion of cartilage was dramatically reduced in mouse knees after treatment with EMR. In conclusion, our results demonstrate that EMR significantly suppressed the progression of CIA and that this action was mediated by the decreased production of TNF-$\alpha$, IL-6, IL-17 and collagen II-specific antibody in the serum. EMR suppressed Th17 cells and reduced level of IL-6 via B cell suppression, and thus, the levels of autoantibodies produced from B cells were decreased. Furthermore, EMR suppressed NKT cells which directly stimulate B cells and develop imbalance of Th1/Th2 cell. Oral administration of EMR (100 mg/kg or 200 mg/kg) significantly suppressed the progression of CIA, which is comparable to that of methotrexate (MTX, 0.3 mg/kg) used as a positive control. We are currently studying the mechanism underlying the therapeutic role for EMR in CIA mice.

• 한국환경농학회:학술대회논문집
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• 한국환경농학회 2009년도 정기총회 및 국제심포지엄
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• pp.3-18
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• 2009

It is difficult for consumers to satisfy high safety request with post-management method such as inspection and surveillance, as various changes in-and-out of the country associated with food safety. In terms of food safety problems related to foods, it is crucial to recognize public health and consumer protection and construct pre-preventive Food Control System. A joint committee, FAO/WHO made the following consultations to the National Food Safety System. ${\circ}$ Approach entirely from farm to table ${\circ}$ Get ready for Risk Analysis System ${\circ}$ Secure transparency ${\circ}$ Establish the optimal policy by evaluating the effect of regulation When it comes to summarizing the consultation, it would be accumulated as two key words; "Efficiency" and "Credibility". Whereas the problem of efficiency focuses on precaution rather than post-management, it requires policy option to maximize consumer's benefit by evaluating the cost for the Food Safety Management and its benefit. Also, analyzing risk's character and amount, demanding an optimal means, and introducing scientific analysis system put much value on the stakeholder's communications are procedure's security which can satisfy both "Efficiency" and "Credibility" simultaneously. Especially, it is emphasized here that Risk Assessment need to be separated from Risk Management. This action is a valid means of credibility security throughout improving transparency. A number of nations and organizations have reformed the method of food management passing through reflection and examination of the prior National Food Safety Management since BSE occurred in Britain, 1996. FSA; Food Standard Agency, AFFSA, EFSA, BfR, and FSC are Risk Assessment Organization functionally separated from Risk Management Organization, JECFA, JMCFA, JMPR, JEMRA in Codex charge Risk Assessment internationally. In case of advanced countries excluding several those such as The U.S. and so forth, though these Risk Assessment Organizations are either separated functionally within Risk Management Organization or operated as apart organ, common factors are in which it has independence as Science Base. While securing independence of Risk Assessment Function, it is a tendency Risk Management should be functionally unified into efficiency as well. Though Germany constructs integral Risk Management System of diverse ways according to social and political conditions of each country such as GFOCP, DVFA, SNFA, CFIS and AQIS, there is a key word in the center, "Securing efficiency of Food Safety Management". However our nation has a representative plural；diversified system with The U.S., we took a step forward for unification as empowering policy's generalization；adjustment and Risk Assessment Function by means of enacting the "Food Safety Fundamental Law" in 2008 and establishing the "Food Safety Policy Commission" with private and governmental sectors in the Prime Minister's office. Even though the unification of Risk Management hereby increased, there is the lack of strengthening function of Risk Assessment and securing independence. It needs to be required for the professional committee in Food Safety Policy Commission to develop as a exclusive office of Risk Assessment by separating from a policy decision. Administrative Branches should reinforce feeble functions such as fundamental investigation；research for carrying out Risk Assessment with securing efficiency throughout reassessment of prior Risk Management Means.

• 식물분류학회지
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• 제36권1호
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• pp.61-89
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• 2006

풍혈지는 여름철에 너덜지대 사면의 암괴 틈에서 찬 공기가 스며 나오며, 또한 결빙현상을 보이는 국소적 저온환경을 형성하는 지역이다. 본 연구에서는 풍혈지에 대한 식물상적 조사를 바탕으로 식물지리학적 중요성과 보존의 필요성을 제시하고자 국내 주요 풍혈지 7개소에 대한 현지 조사를 실시하였다. 그 결과, 풍혈지에서 한들고사리, 두메고사리 좀미역고사리, 월귤, 뚝지치 등 식물지리학적으로 중요한 다수의 북방계 식물들이 조사되었다. 또한 수직분포면에서도 산우드풀, 민둥인가목, 요강나물, 산새풀, 집사초와 같은 아고산식물들이 해발이 낮은 풍혈지에 생육하는 특이성을 보이고 있었다. 풍혈지는 빙하기에 남하했던 북방계 식물들이 최후빙기 이후 이주과정에서 국소적 기후환경에 적응, 고립되어 있는 피난처로 판단되어진다. 고피난처인 풍혈지는 기상학, 지형학적 중요성뿐만 아니라 식물지리학적으로도 아주 중요한 서식지 형태로 소집단으로 격리 분포하는 북방계 식물 종들에 대한 보존생물학적 연구를 통한 합리적인 현지내 외 보존대책의 수립이 시급하다고 판단된다.

• 한국심리학회지 : 문화 및 사회문제
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• 제14권1호
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• pp.101-123
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• 2008

본 연구는 남녀 대학생을 대상으로, 어머니와 연합된 성공/실패에 대한 표상을 알아보기 위해 시도되었다. 이를 위해 연구 1에서는 어머니/바구니와 성공/실패를 이중점화자극으로 100ms 동안 제시하고 난 뒤, 150ms 후(SOA 250ms)에 수용/거부와 관련된 목표자극(probe)을 제시하고 어의판단에 걸리는 시간을 측정하였다. 그 결과, 어머니조건의 반응이 통제조건보다 빨랐으며, 수용에 대한 반응이 거부 반응보다 빨랐고, 여자집단의 반응이 남자보다 빨랐다. 연구 2에서는 남녀별로 애착 고집단과 저집단을 나누어, 어머니와 성공/실패를 이중점화시킨 뒤 수용/거부에 대한 어의판단 시간을 측정하였다. 그 결과, 성공/실패와 수용/거부 간에 상호작용이 나타나, 성공-수용에 대한 반응은 가장 빨랐고, 실패-수용, 실패-거부, 성공-거부의 순으로 반응이 느려졌다. 한편 남자집단에서는 애착고저 집단 간에 유의미한 차이가 없고 상호작용도 나타나지 않았지만, 여자집단에서는 3원 상호작용이 나타났다. 즉 여자 애착 고집단에서는 성공-수용, 성공-거부에 대한 반응차이가 크지 않았고, 실패-거부에 대한 반응이 매우 느렸으나, 여자 애착 저집단에서는 성공-수용은 매우 빠른데 비해 성공-거부는 매우 느렸다. 이러한 결과는 자기 긍정성 및 성별, 애착유형에 따라 다른 성공/실패 도식과 관련하여 논의되었다.

• 대한간호학회지
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• 제4권1호
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• pp.162-178
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• 1974

The present study is purported to provide a basic information to be utilized by nurses to care and attend effectively for patients nearing the moment of death. Therefore, the primary purpose of the study has been placed upon grasping an understanding of the trends of death in general. For this purpose: 1. By utilizing the schneidman questionnaire, the trend of death has been categorized by 6 parts and analyzed. 2. A search has been conducted to find out dying patient's needs, nurse's attitudes viewed by the patient, and nurse attitudes to dying patient. The followings are itemized results of analysis: 1. Analysis by the schneidman questionnaire. (1) In general concepts of death. the first sighting of the occurrence of death was experienced upon strangers, grandfather and great grandfather. The death is openly discussed among people of all ages and sex. Ages in which the death is mostly feared were from 12 to well over 70 yews old that are evenly distributed regardless of difference in age. (2) As to the attitudes toward death the occurrence of death to most closely associated person influenced most upon the attitude of their own termination of lives. Among the reading materials, the maximum influence was effected by the Bible. In terms of religion, the thoughts of death were Influenced by religions education in case of the believers of the western religions (36%), and by their own health and physical conditions in case of the believers in the oriental religions (35%). In case of non-believer, their attitude toward death were largely determined through their own thinking meditation (45%). People aged 20 or thereunder revealed that they wished to know the day of their own death to be occurred (58%). However, the older the less thor wanted to know. (3) As to the choosing the time of death, 57% preferred senility, and 30% preferred the time in mediately following the prime period of their lives in general. In terms of religion, 85% of the believer in the oriental religion preferred senility, and 67% in the western religion, 58% in others, Therefore. the desiring of their lives to be terminated in earlier stage, not by the natural senility. sequenced as follows : Others, western religions and oriental religions. (4) Referring to the disposal of the corpse under the assumption that it had already occurred, majority desired the burial system. There has been seen a slight tendency to consider the importance of holding funeral services for the sake of survivors. Concerning the life insurance policy, it showed that the nurse had less belief in it than the patient (5) Upon the subject of life-after-death. religion wise, 72% of western religion believers preferred to have an existence of life-after-death: Among the believers of oriental regions, 35% desired this category, 30% did not mind either way. and 35% did not desire the existence of such a life-after-death. In others, 53% did not mind whether or not such a life existed. (6) In general, serious thoughts were not being attended to the commitment of suicide. 37% emphasized that such an act should be prevented. However, 30% insisted that such commitment should not be bothered, and that society possesses no right to prevented it. More male wished to commit suicide (13%) than females (9%). 2. Nurse's attitudes toward terminal patients and patient's needs. In the instance where the patient realized that their death is imminent, most of them showed desire to discuses mainly on the problems of life. When faced a situation of this nature, it is revealed that 40% of nurses could not furnish appropriate care for them.

• 한국식품영양학회지
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• 제25권1호
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• pp.132-141
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• 2012

본 연구는 도시지역에 거주하는 소비자 1,343명을 대상으로 쇠고기 구매와 관련된 요인과 쇠고기 유통제도에 대한 소비자 의향을 설문조사하여 쇠고기 마케팅에 활용하고자 실시하였다. 가정에서 쇠고기를 구입하는 회수는 소비자의 사회, 경제적 위치에 따라 다르게 나타나, 서울시와 광역시가 일반시보다, 고소득층이 저소득층보다, 40대가 20대보다 더 자주 구입하고 있는 것으로 나타났다. 구입 장소는 서울시, 광역시 등 대도시 거주자와 월 200만 원 이상의 고소득층은 백화점, 할인점을 주로 이용하고 있는 반면, 중소도시 및 저소득층은 전문점 및 정육점을 주로 이용하였다. 시판 쇠고기에 대한 개선 사항은 대도시 거주자, 고소득층 및 30대 이상은 위생, 포장방법을 중소도시, 저소득층 및 20대는 육질의 균일성 및 가격 인하를 요구하였다. 등급제에 대한 인식은 거주지, 월소득 및 연령층에 따라 다르게 나타났으며, 중소도시 거주자, 저소득층 및 20대와 40대에서 부정적으로 나타났다. 구분판매제에 대한 의향은 중소도시 거주자, 200만 원 이상의 고소득층, 30~40대의 가정주부에서 긍정적으로 평가하였으나, 상당비율의 소비자가 이 제도에 대해 모르거나 중요치 않은 것으로 인식하고 있었다. 쇠고기 구매시 고려하는 사항 중 선호 부위는 등심, 양지, 갈비 순이었으며, 구매시 고려요인은 부위, 가격, 원산지 순이었다. 또한 품질 요인으로는 신선도, 색깔 등을, 표시사항에 대해서는 가격, 품종 부위 순으로 중요시 하는 것으로 나타났다.

• 한국임상수의학회지
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• 제28권3호
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• pp.297-302
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• 2011

조류병원성 대장균 (APEC)은 가금에서 많은 장관외 질병을 야기한다. 병원성 인자 중 하나인 P-fimbriae 또한 질병과 밀접하게 관련되어 있다. 이번 연구에서 마우스에 P-fimbriae의 subunit 들인 PapA와 PapG를 발현하는 재조합 약독화 Salmonella Typhimurium 백신균주 접종 후 APEC 방어에 필요한 면역반응 유도 여부를 알아보기 위한 실험을 수행하였다. 각 백신 균주로 경구 접종 후 각 항원에 대한 serum IgG 항체 역가는 접종 후 4주째부터 대조군에 비해 항체 역가가 높게 유도되기 시작하여 실험이 끝날 때까지 높은 항체 역가가 계속 유지 되었다. 한번 접종 된 경우보다 추가 접종 된 군에서 보다 높은 항체 역가가 관찰되었다. 더불어 각 항원에 대한 mucosal IgA 역가 또한 높게 유도되었다. 두 균주를 혼합하여 접종 하였을 경우에는 각 백신 균주를 접종하였을 경우보다 높은 serum IgG와 mucosal IgA의 역가가 관찰되었다. 이 결과는 이들 백신 균주가 면역원성이 있음을 확인하는 결과였다. 또한 helper T cells type을 알아보기 위해 IgG1과 IgG2a의 항체 역가를 측정하여 본 결과 각 백신 균주를 접종하였을 경우에는 IgG2a의 항체 역가가 IgG1의 항체 역가 보다 월등히 높은 이들 백신 균주를 접종 하였을 경우에는 Th1-type의 면역 반응이 유도되지만 두 백신 균주를 혼합 접종하였을 경우에는 Th1-과 Th2-type 모두를 유도하는 것으로 관찰되었다. 이 결과를 통해서 이들 두 백신 균주를 혼합 접종 하였을 경우에는 세포성 면역뿐만 아니라 체액성 면역 모두를 유도할 수 있음을 확인할 수 있었다.