• Pediatric Infection and Vaccine
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• 제31권1호
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• pp.153-157
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• 2024

Manubriosternal 관절의 패혈성 관절염은 특히 청소년에서 드물게 발생하는 질환으로, 종종 근골격 흉통, 갈비뼈염 등과 같은 보다 흔한 진단과 비슷하게 비특이적 증상으로 나타난다. 우리는 17세 소녀의 패혈성 관절염 사례를 보고하며 이러한 질환의 진단과 치료에 대한 어려움을 강조한다. 처음에는 일시적 비특이적 흉통으로 진단된 급성 흉통으로 시작하여, 환자의 응급실 재방문에서 고열과 같은 증상이 심화되어 추가적인 영상 촬영을 진행하였다. 결과적으로 Manubriosternal 관절의 패혈성 관절염 진단이 확인되었으며, 혈액 배양 결과 메티실린 감수성 황색포도상구균이 검출되었다. 진단 지연은 전형적인 증상의 부재 및 환자의 입원에 대한 소극적 태도 등이 영향을 끼친 것으로 보인다. 이 사례는 흉통이 있는 청소년에서 드문 감염 원인을 고려하는 중요성과 전형적이지 않은 해부학적 부위에서의 감염 의심의 필요성을 강조한다.

• 한국식품영양학회지
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• 제11권2호
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• pp.171-178
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• 1998

K14 환자는 유방암 수술, 방사선 치료, 피부이식 수술, 무릎 관절통의 기왕력이 있는 고령의 여성 호흡 곤란증 환자로서 문진과 진찰, 혈압, 비만도 측정, 임상병리, 흉부 X-선, 심전도와 심초음파, 폐기능 검사 등 체계적인 심폐기 질환의 진단 결과 비난증과 고혈압, 좌심실 비대, 만성 폐질환의 소견이 있어 심폐기능 모두에서 문제성이 발견되었다. 검사 결과들의 정밀한 판독법 및 장기-치료 관찰 결과를 임상문헌과 함께 고찰하였다.

• 대한족부족관절학회지
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• 제5권1호
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• pp.55-61
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• 2001

Purpose: To evaluate the clinical and functional results of ankle arthroplasty and to analyze the complications in total ankle arthroplasty. Materials and Methods: Between October 1988 and October 1991, the total ankle arthroplasty had been performed in eight ankle joints of seven patients.. There were five patients with rheumatoid arthritis, one with osteoarthritis and one with traumatic arthritis. One patient had bilateral replacement. New Jersey type of prosthesis was used in six patients and one patient was performed with Odland type of prosthesis. The average age at surgery was 42.3 years (range, 33-54 years). The average follow-up period was 8.2 years (range, 6-10.5 years). Clinical evaluation was assessed according to the Ankle-Hind Foot Scale of American Orthopedic Foot and Ankle Society. Results: The average score was 81.4 (range, 76 - 90) at the most recent follow-up. All patients were satisfied with their clinical results. Relief of pain was excellent in most patients, but postoperatively there was no significant improvement in range of motion. One patient had arthrodesis at three year six months after total ankle arthroplasty due to deep infection. Conclusion: This study shows total ankle arthroplasty is a good alternative treatment in selected cases of osteoarthritis and rheumatoid arthritis.

• Clinical and Experimental Pediatrics
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• 제53권2호
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• pp.262-266
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• 2010

$TNF-{\alpha}$ 는 소아기 류마티스모양 관절염의 병태생리학에 관여하는 주요 cytokine 이다. Etanercept 는 $TNF-{\alpha}$ 억제제 중 하나로 소아기 류마티스모양 관절염에 효과적인 약물로 각광받고 있다. Etanercept의 주요 부작용은 면역력 저하에 의한 감염으로, 대게 중등도의 상기도 감염이 대부분으로 알려져 있으나, 최근 중증의 감염도 보고되고 있다. 저자들은 소아기 류마티스모양 관절염 환자가 etanercept를 14개월간 투약 후 발생한 뇌염 1예를 경험하였기에 보고하는 바이다.

• 대한관절경학회지
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• 제16권2호
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• pp.180-184
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• 2012

진균에 의한 감염성 관절염은 면역 억제 치료자, 약물 남용자, 장기간의 항생제 투여자 등에서 발생하는 드문 질환으로 특히 건강한 성인에서의 감염은 매우 드물다. 진균에 의한 슬관절의 감염성 관절염은 국내에서 2예의 보고가 있으나, 건강한 성인에서 발생한 진균성 슬관절염은 아직 보고된 바가 없는 실정이다. 이에 저자들은 건강한 성인에서 반복적인 관절 내 스테로이드 주사 후 발생한 진균성 관절염 및 이와 동반한 슬와낭종의 관절경적 치료를 경험하여 문헌 고찰과 함께 보고하는 바이다. 진균성 슬관절염은 특징적인 임상상이 없는 드문 질환으로, 진단에 있어 어려움이 있으므로 면밀한 관찰과 주의를 요한다.

• 대한족부족관절학회지
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• 제26권3호
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• pp.143-147
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• 2022

Past research has reported that the common causes of ankle arthritis include trauma, congenital deformity, and degeneration. Among them, fracture-induced post-traumatic arthritis is most common. For patients with ankle fractures, an anatomical reduction is performed through surgical treatment. However, insufficient reduction or malunion of the fracture site may change the alignment of the ankle joint, resulting in valgus or varus deformities. Currently, most operative options for valgus arthritis aim to either restore joint alignment and/or reduce the uneven load on the cartilage. In this report, we would like to share our clinical experience of a patient with posttraumatic valgus ankle arthritis caused by severely comminuted fracture and dislocation. A satisfactory outcome could be obtained with combined fibular lengthening osteotomy and medial displacement calcaneal osteotomy.

• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 2001년도 추계학술대회 및 정기총회
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• pp.41-76
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• 2001

Rheumatoid arthritis is an incurable chronic inflammatory and destructive arthopathy that affects 1% of the population world-wide. It has substantial personal, social and economic costs. The long-term prognosis is poor: 80 percent of affected patients will become disabled within 20 years after onset of disease. Medical costs of rheumatoid arthritis average ∼$ 6000 (US) per patient (1), Current antirheumatic drugs have limited efficacy and many side effects and more importantly they do not improve the long-term prognosis of rheumatoid arthritis (2). After a decade of few notable advances in therapy, several biological response modifiers that target pathophysiological processes in the disease have now emerged in the clinic. These new drugs are termed biological agents, and although information about their use in the clinic is still limited to short term treatment, they appear to have the ability to modify disease progress. In addition, COX-2 selective agents have now been approved that have comparable efficacy with standard NSAIDs, but fewer gastrointestinal side effects (3). Thus today many more therapeutic options are suddenly open to patients that even five years ago had little hope of relief from chronic pain and inflammation.

• 대한족부족관절학회지
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• 제22권1호
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• pp.1-7
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• 2018

Ankle arthrodesis is a common and standard treatment for patients with end-stage ankle arthritis. The surgical goals of ankle arthrodesis are to obtain bony union between the tibia and talus with adequate alignment, and provide a pain-free plantigrade foot for weightbearing activities. To achieve successful fusion, the surgeon should closely examine the patient's factors before surgery, particularly the following: adjacent arthritis and deformity, infection, avascular necrosis of talus, Charcot arthropathy, and rheumatoid arthritis. Recently, ankle arthroplasty has been reported to provide satisfactory clinical results. On the other hand, long-term follow-up results are still lacking, and considering the various complications of arthroplasty, ankle arthrodesis is still the primary surgical treatment for advanced arthritis of the ankle joint.

• 대한족부족관절학회지
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• 제17권4호
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• pp.329-333
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• 2013

Controversies exist regarding the treatment options for the end-stage arthritic change in the lateral tarsometatarsal joints. Arthrodesis has been frequently performed, but has a disadvantage of sacrificing a mobile joint. Resection arthroplasty also gained its popularity, especially in the patients with Rheumatoid arthritis, but possible hypermobility can lead to deformity. We report a successful clinical outcome of a patient with Rheumatoid arthritis in the 4th, 5th tarsometatarsal joints treated with tendon interpositional arthroplasties.

• Journal of Yeungnam Medical Science
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• 제20권1호
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• pp.79-84
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• 2003

Pyoderma gangrenosum is uncommon neutrophilic dermatosis characterized by richness of the mature neutrophilic polynuclear dermal infiltrate. Pyoderma gangrenosum is associated with variable diseases, most commonly inflammatory bowel disease, hematological diseases, malignancies, but it is reported rarely in rheumatoid arthritis. We report a case of pyoderma gangrenosum in rheumoid arthritis patient. A 50-year-old woman admitted to our hospital due to painful pretibial ulcerative skin lesions. She had been treated as rheumatoid arthritis for 8 years. At admission, body temperature was $36.5^{\circ}C$ and other vital sign was unremarkable. Physical examination revealed right pretibial ulceration, multiple pustules on left pretibial area and both palms. Laboratory studies revealed WBC count 7,600/uL (neutrophils 60.3%, eosinophil 3.2%), hemoglobin 11.4 g/dL, platelet count 319,000/uL, ESR 65 mm/hour. Other lab findings were also unremarkable. Skin biopsy was done, which showed dense dermal infiltrate of neutrophils and wound culture were negative. By 8 weeks after systemic high dose corticosteroid (1 mg/kg/day), cyclosporine A (5 mg/kg/day), sulfasalazine 2 g therapy, symptoms and skin ulceration were being improved. Without skin relapse, she is followed up our hospital with low dose corticosteroid and sulfasalazine.