• 한국응용과학기술학회지
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• 제38권6호
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• pp.1512-1523
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• 2021

본 연구의 목적은 남자 테니스 선수의 생맥산 섭취가 혈중 지질 및 동맥경화 지수에 미치는 영향을 조사하는 것이었다. 남자 대학 테니스 선수 17 명을 4 주간의 고강도 테니스 하계훈련 중 생맥산 섭취 여부에 따라 생맥산 섭취군(n=9)과 위약 대조군(n=8)으로 나누었다. 테니스 하계훈련은 4 주간 주 5 회 실시하였으며, 운동강도는 예비심박수의 70~90%로 실시하였다. 생맥산은 아침 식사 전, 운동 중, 운동 중, 운동 후 1 회 110ml, 저녁 식사 후 1 일 총 7 회 770ml 를 섭취하였다. 모든 데이터에 대해 평균 및 표준 편차를 사용하였으며, 시기간 및 생맥산 섭취그룹의 효과를 확인하기 위하여 반복측정분산분석법을 사용하였고, 생맥산 섭취 후 혈중 지질의 차이에 대한 관련성을 알아보기 위하여 Pearson 의 상관분석을 실시하였다. 본 연구결과, 생맥산 섭취군은 혈중 지질(중성지방, 총콜레스테롤, 고밀도지단백콜레스테롤, 저밀도지단백 콜레스테롤)과 동맥경화지수가 유의하게 개선되었으며, ∆TG, ∆LDL 및 ∆TC 간에는 유의한 상관관계가 나타났다. 결론적으로 남자 대학 테니스 선수의 고강도 트레이닝 시 생맥산 섭취는 혈중 지질 및 동맥경화 지수에 긍정적인 영향을 미칠 수 있어 운동 보조제로서 효과적인 스포츠 음료가 될 수 있음을 시사한다.

• Journal of Periodontal and Implant Science
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• 제5권1호
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• pp.16.2-16.2
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• 1975

• 한국식품영양학회지
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• 제5권2호
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• pp.99-103
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• 1992

Patterns in the outbreaks of senile diseases were investigated on 1, 264 workers by special examination among the 43, 210 industrial workers by the screening test performed in Kwang-ju and Chon-nam Branch of Korean Industrial Health Association from January 4 to December 31 in 1991. The results are summarized as follows : 1) Prevalence rate of senile diseases of industrial workers was 2.9%. And prevalence rate according to the kinds of senile diseases was observed in the order of hepatitis (0.9%), hypertension(0.7%), diabetes mellitus(0.5%), anemia(0.4%). 2) Prevalence rate of complicated senile diseases of industrial workers was 0.5%. And prevalence rate according to kinds of complicated senile diseases was observed in the order of others hypertension and arteriosclerosis (0.1%), HBV and others chronic hepatitis(0.1%), essential hypertension and arteriosclerosis(0.03%), iron deficiency anemia and leukopenia(0.03%).

• 생약학회지
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• 제18권4호
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• pp.241-248
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• 1987

Woohwangchungsim-Won has been widely used for the treatment of appoplexy, hypertension, arteriosclerosis, insomnia and cerebrovascular accident, etc in oriental hospital and pharmacy. In order to investigate the efficacy of Woohwangchungsim-Won, the water extract of it were bioassayed for isolated ileum, blood vessels, blood pressure, heart and diuresis. The results of this studies were as follows; Spontaneous motilities of isolated ileum of mice were strongly suppressed, and contraction of isolated ileum of mice and guinea-pigs induced by acetylcholine chloride, barium chloride and histamine were inhibited. Vaso-dilating action due to vascular smooth muscle relaxation in frogs and rabbits, and hypotensive action in anesthetized rabbits were noted. Negative inotropic action on the isolated frog heart and diuretic effect in rabbits were shown.

• 한국방사선학회논문지
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• 제14권5호
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• pp.705-713
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• 2020

동맥경화는 혈관이 좁아지면서 탄력을 잃어 혈액 순환 장애가 발생하는 질병으로, 최근 증가하는 심혈관 및 뇌혈관 질환의 잠재적 원인이 된다. 경동맥초음파 검사는 동맥경화 정도를 평가하여 심혈관 및 뇌혈관 질환의 예측인자로 사용되고 있다. 이에 본 논문은 경동맥초음파 검사에서 내중막 두께 증가와 여러 임상변수들 간 상관성을 알아보고자 하였다. 경동맥초음파검사 소견을 가지고 있는 환자를 대상으로 경미한 내중막 두께 비후, 경화반, 유의한 협착 3단계로 분류하였다. 경동맥의 동맥경화 정도와 신체적 특성(성별, 연령, 신체질량지수법, 혈압), 혈액검사(총콜레스테롤, 중성지방, 고밀도지단백질, 저밀도지방단백질, 크레아틴포스포키나제, 공복혈당)와 동맥경화도 검사에서 계측된 CAVI(Carotid Ankle Vascular Index : 혈관연령) 데이터를 수집하였다. 경동맥 내중막 두께는 고혈압, 고지혈증, BMI 등의 변수와 상관관계가 있었으며, 또한 CAVI가 증가될수록 심혈관계 질환의 위험요인과 상관관계가 있음을 확인하였다.

• 대한한의학회지
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• 제23권2호
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• pp.19-27
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• 2002

Objective : This study was designed to investigate the effect of Hyeolbuchukeo-tang (HCT) on NO production and the molecular mechanism of NO production modulated by HCT in the primary VSMC (vascular smooth muscle cells). Method : Primary VSMC was established from aorta and cultured VSMC used in this study. NO production of VSMC was assayed by Griess reagent and the expression of iNOS gene was assayed by Western, RT-PCR. Result : $TNF-{\gamma}$ induced NO production, but $IFN-{\gamma}$ or HCT alone did not induce NO production in cultured VSMC. However, $IFN-{\gamma}$ or HCT potentiated NO production in $TNF-{\gamma}-treated$ VSMC in a time- and dose-dependent manner. $TNF-{\gamma}$ induced the iNOS gene expression corresponding to NO production in $TNF-{\gamma}-treated$ VSMC. HCT potentiated NO production in $TNF-{\gamma}-treated$ VSMC by about 20%, but HCT did not increase the level of iNOS mRNA in $TNF-{\gamma}-treated$ VSMC. HCT slightly increased the level of iNOS protein in $TNF-{\gamma}-treated$ VSMC. Calcium ionophore A23187 decreased NO production in $TNF-{\gamma}-treated$ VSMC, but HCT attenuated the effect of A23187. Conclusion : As NO is deeply involved in the development of arteriosclerosis and dilation of blood vessels, drugs or chemicals modulating NO production in VSMC could be used for preventing and treating arteriosclerosis. Considering the effect of HCT on the modulation of NO production in VSMC, MCT has a potential capacity for preventing and treating diseases of the circulation system including arteriosclerosis.

• Korean Journal of Acupuncture
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• 제27권2호
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• pp.107-120
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• 2010

Objectives : The aim of this study is to measure pulse waveforms by applying 5-level graded pressure, and selecting optimum pulse waveforms. Also to proposing the possibility of using AW(Area of the 1/3 upper height of h1) rate in respect to AT(Total Area) for risk assessment of hypertension or arteriosclerosis is another aim of the study. Methods : Pulse waveforms of normotensive were measured by 5-level graded pressure. The pulse waveforms well reflecting properties of blood vessel(having the largest h1) were selected for optimum pulse waveforms. Various parameters(h-parameter, t-parameter, and others) of optimum pulse waveforms were analyzed. AIx(Augmentation index) was calculated by height-parameters to assess arterial stiffness. The area rate of the 1/3 upper height for h1 in respect to total area was analyzed according to aging. Results : According to aging 1. in height-parameter, h2 and h3 were increased but h5 was decreased. 2. In time-parameter, t2, t3, and t5 were getting short. 3. Area of systolic period was increased, and that of diastolic period decreased. 4. AIx rose by aging. 5. AW was significantly increased despite no changes in AT. Conclusions : By analyzing optimum pulse waveforms of 5-level graded pressure method, we could complement weakness of single graded pressure method. Also, possibility of applying the AW rate to risk assessment of hypertension or arteriosclerosis was confirmed in normotensive population which might not be assessed by AIx.

• 대한한방내과학회지
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• 제41권3호
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• pp.434-446
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• 2020

Objectives: The cardio-ankle vascular index (CAVI) and ankle-brachial index (ABI) are non-invasive methods to evaluate cardiovascular disease and arteriosclerosis. This study investigated the relationship between CAVI, ABI, and factors related to arteriosclerosis. Methods: This study included 535 healthy adults who underwent health examinations in 2019. We analyzed the correlation between CAVI, ABI and clinical variables. Multiple regression analysis was performed on the independent clinical variables associated with CAVI and ABI. Results: The correlation analysis of CAVI showed that body mass index (BMI) and HDL-cholesterol (HDL-C) had a negative correlation, and the other variables had a significant positive correlation. The correlation analysis with ABI on the right side showed that age, diastolic blood pressure (DBP), gender, and LDL-cholesterol (LDL-C) had a significant positive correlation, while HDL-C had a significant negative correlation. There was no statistical significance on the left. In the multiple regression analysis, DBP, age, BMI, gender, and HDL-C were proved to be independent factors in CAVI (right) (R²=0.365); DBP, age, gender, BMI, fasting blood sugar, and total cholesterol in CAVI (left) (R²=0.357); and age, gender, DBP, and systolic blood pressure in ABI (right) (R²=0.133). There were no statistically significant factors in ABI (left). It could be inferred that smoking and drinking are determinants that play an important role in CAVI. Conclusion: CAVI showed a high correlation with gender, age, and blood pressure. A significant correlation between CAVI and serum lipid values could be observed, but this showed a low correlation coefficient. ABI showed a high correlation with age and DBP. These results support the use of CAVI and ABI as primary diagnostic devices in medical treatment.

• Journal of Chest Surgery
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• 제19권3호
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• pp.522-527
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• 1986

There have been several reports of abdominal aortic aneurysm according to increase in life span and greater awareness of the diagnosis in Korea. We had a surgical experience of abdominal aortic aneurysm due to arteriosclerosis in 76 years old male. With abdominal sonogram, he was diagnosed. Aortoiliac bypass was done with double velour Dacron Y graft. Postoperative course was uneventful.

• 대한영양사협회학술지
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• 제8권4호
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• pp.333-341
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• 2002

Obesity, a state of having excessive body fat enough to attack one's health, is most blamed for causing chronical degenerative illness such as hypertension, diabetes mellitus as well as arteriosclerosis. According to many studies, the program for the weight control was the most demanded at the worksites. This study was designed to investigate the correlation between the degree of obesity and blood parameters of the employees at the worksites. The results of periodic medical examination for 571 employees(male: 418, female: 153) were analyzed; Age, BMI, systolic blood pressure(SBP), diastolic blood pressure(DBP), hemoglobin(Hb), fasting blood sugar(FBS), total-cholesterol(TC), serum glutamic oxaloacetic transaminase (sGOT), serum glutamic pyruvic transaminase(sGPT) and $gamma$-glutamyl transpeptidase($gamma$-GTP). Pearson correlation coefficient was used to find out the correlation between BMI and each blood parameters. In the case of male, 27.3% of the subjects were over-weight. The subject's age and their blood levels of uric acid, FBS, sGOT and sGPT did not show any significant difference regardless of BMI's, while SBP, DBP, Hb, TC and $gamma$-GTP levels of the overweight group were significantly higher than those of normal group. In the case of female, 9.2% of the subjects were over-weight. This study shows that the implementation of weight control program is required at the worksites