• Earthquakes and Structures
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• v.10 no.3
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• pp.645-667
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• 2016

The 750 m long "De Bosset" bridge in the Cephalonia Island of Western Greece, being the area with the highest seismicity in Europe, was constructed in 1830 by successive stone arches and stiff block-type piers. The bridge suffered extensive damages during past earthquakes, such as the strong M7.2 earthquake of 1953, followed by poorly-designed reconstruction schemes with reinforced concrete. In 2005, a multidisciplinary project for the seismic assessment and restoration of the "De Bosset" bridge was undertaken under the auspices of the Greek Ministry of Culture. The proposed retrofitting scheme combining soil improvement, structural strengthening and reconstruction of the deteriorated masonry sections was recently applied on site. Design of the rehabilitation measures and assessment of the pre- and post-interventions seismic response of the bridge were based on detailed in-situ and laboratory tests, providing foundation soil and structural material properties. In-situ inspection of the rehabilitated bridge following the strong M6.1 and M6.0 Cephalonia earthquakes of January 26th and February 3rd 2014, respectively, revealed no damages or visible defects. The efficiency of the bridge retrofitting is also proved by a preliminary performance analysis of the bridge under the recorded ground motion induced by the above earthquakes.

• Journal of Animal Reproduction and Biotechnology
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• v.37 no.3
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• pp.162-168
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• 2022

Mecoprop-p, a chlorophenoxy herbicide, has been widely used since the 1980s. Due to its high water solubility, it could be detected in the aquatic environment, as it has already been detected in the surface water or groundwater in several countries. The toxicity of other chlorophenoxy herbicides has been reported; however, there are few studies on the toxicity of mecoprop-p, one of the chlorophenoxy herbicides, on aquatic organisms. Here, we investigated the toxic effects of mecoprop-p using zebrafish. After mecoprop-p exposure, we observed that the zebrafish larvae eyes did not form normally, heart edema was generated, and the body length was shortened. The number of cells undergoing apoptosis also increased in the anterior part including head, heart, and yolk sac of the mecoprop-p-treated zebrafish compared to the untreated controls. Moreover, cardiovascular structures, including the heart and aortic arches, were also malformed after exposure to mecoprop-p. Therefore, our results suggest that mecoprop-p could cause abnormal development in zebrafish larvae and there is also a high possibility that mecoprop-p would be toxic to other aquatic organisms.

• Earthquakes and Structures
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• v.23 no.1
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• pp.13-21
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• 2022

Masonry constructions exhibit uncertain behaviors under dynamic effects such as seismic action. Complex issues arise in the idealization of structural systems of buildings having different material types and mechanical properties. In this study, the structural behavior of a vaulted masonry building constructed using full clay brick and lime-based mortar and sitting on consecutive arches was investigated by experimental and numerical approaches. The dimensions of the structure built in the laboratory were 391 × 196 cm, and its height was 234 cm. An incremental repetitive loading was applied to the prototype construction model. Along the gradually increasing loading pattern, the load-displacement curves of the masonry structure were obtained with the assistance of eight linear displacement transducers. In addition, crack formation areas, and relevant causes of its formation were determined. The experimental model was idealized using the finite element method, and numerical analyses were performed for the area considered as linear being under similar loading effect. From the linear analyses, the displacement values and stress distribution of the numerical model were obtained. In addition, the effects of tie members, frequently being used in the supports of curved load-bearing elements, on the structural behavior were examined. Consequently, the experimental and numerical analysis results were comparatively evaluated.

• Steel and Composite Structures
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• v.42 no.6
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• pp.747-764
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• 2022

The design codes and calculation methods related to soil-steel composite bridges and culverts only specify the minimum soil cover depth. This value is connected with the bridge span and shell height. In the case of static and dynamic loads (like passing vehicles), such approach seems to be quite reasonable. However, it is important to know how the soil cover depth affects the behaviour of soil-steel composite bridges under seismic excitation. This paper presents the results of a numerical study of soil-steel bridges with different soil cover depths (1.00, 2.00, 2.40, 3.00, 4.00, 5.00, 6.00 and 7.00 m) under seismic excitation. In addition, the same soil cover depths with different boundary conditions of the soil-steel bridge were analysed. The analysed bridge has two closed pipe-arches in its cross section. The load-carrying structure was constructed as two shells assembled from corrugated steel plate sheets, designed with a depth of 0.05 m, pitch of 0.15 m, and plate thickness of 0.003 m. The shell span is 4.40 m, and the shell height is 2.80 m. Numerical analysis was conducted using the DIANA programme based on the finite element method. A nonlinear model with El Centro records and the time history method was used to analyse the problem.

• Restorative Dentistry and Endodontics
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• v.46 no.3
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• pp.34.1-34.9
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• 2021

Objectives: This study aimed to assess the presence of pulp stones through an examination of cone beam computed tomography images and correlate their prevalence with age, sex, dental arch and side, tooth type, and restoration type and depth. Materials and Methods: Cone beam computed tomography images obtained from 673 patients and archival data on 11,494 teeth were evaluated. The associations of pulp stones with age, sex, dental arch and side, tooth type, and restoration type and depth were noted. All the measurements were subjected to a χ² test and one sample χ² test (p < 0.05). Results: In the study group, 163 (24.2%) patients and 379 (3.3%) teeth had at least one pulp stone. The pulp stone frequency in those aged 30-39 years was significantly greater than in those aged 18-29 and ≥ 60 years, and the frequency was higher in females than in males (p < 0.05). The highest prevalence of pulp stones was found in maxillary dental arches and molar teeth (p < 0.05). Pulp stones were significantly more common in medium-depth restorations (p < 0.05). Conclusions: Maxillary molar teeth, medium-depth restorations, individuals aged 30-39 years and females had a greater percentage of pulp stones.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.29 no.6A
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• pp.617-624
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• 2009

This study deals with the free vibrations of the elastica shaped arch with linear taper. The shape of elastica is obtained from the Bernoulli-Euler beam theory. Differential equations governing free vibrations of such arch are derived and numerically solved to determine natural frequencies, in which three kinds of taper type and two kinds of end constraint, respectively, are considered. For validating the theories presented herein, the frequency parameters obtained in this study are compared to those of SAP 2000. As results of the numerical analyses, effects of end constraint, taper type, slenderness ratio and section ratio on the lowest four non-dimensional frequency parameters are extensively investigated.

• Journal of Microbiology and Biotechnology
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• v.33 no.12
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• pp.1543-1551
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• 2023

The recently published high-resolution R388 T4SS structure provides exciting new details about the complete complex of T4SS, including the components making up the stalk and arches, numerous symmetry mismatches between regions of the complex, and an intriguing interpretation of the closed stalk and radial symmetry of the inner membrane complex, which is related to pilus biogenesis assembly. However, there are a few unidentified densities in the electron microscopy map and portions of the identified component sequences for which the structure is not yet known. It is also unclear how well this minimized DNA-transporting T4SS predicts the structure of other T4SSs, such as expanded systems and those that transport proteins rather than DNA. In this review, we evaluate what can be inferred from the recent high-resolution structure of the R388 T4SS with respect to the Cag and Dot/Icm systems. These systems were selected because, given what is currently known about these systems, we expect them to present most structural differences compared to the R388 T4SS structure. Furthermore, we discuss bacterial physiology and diversity, the T4SS structures and their variations between different bacterial species. These insights may prove beneficial for researchers who elucidate the structure and functions of T4SS in different bacterial species.

• Anatomy and Cell Biology
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• v.57 no.3
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• pp.392-399
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• 2024

The recurrent laryngeal nerve is a bilateral branch of the vagus nerve that is mainly associated with the motor innervation of the intrinsic muscles of the larynx. Despite its bilateral distribution, the right and left recurrent laryngeal nerves display unequal length due to embryological processes related to the development of the aortic arches. This length asymmetry leads to theories about morphological compensations to provide symmetrical functions to the intrinsic muscles of the larynx. In this study we investigated the developmental and cross-sectional morphometrics of the recurrent laryngeal nerves in human fetuses. Fifteen stillbirth fetuses donated to anatomical and medical research were used for investigation. Fetuses had intrauterine age ranging from 30 to 40 weeks estimated by biometry methods. Specialized anatomical dissection of the visceral block of the neck was performed to prepare histological samples of the recurrent laryngeal nerves in its point of contact with the larynx, and morpho-quantitative techniques were applied to evaluate the epineurium and perineural space of the recurrent laryngeal nerves. No statistical difference in the cross-sectional morphology of the epineurium and perineural space between right and left recurrent laryngeal nerves intra-individually was confirmed, however, we found evidence that these structures are under greater development in the left recurrent laryngeal nerve during 30 to 40 weeks of intrauterine life. Our data suggest that the nerves are under morphological development that possibly set the stage for accommodation of larger diameter and myelinization of the left recurrent laryngeal nerve during post-natal life.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.34 no.3
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• pp.376-382
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• 2008

Anterior open bite is a condition in which maxillary and mandibular incisors do not occlude at central occlusion. It is a vertical discrepancy of the jaws and dental arches that has many etiologic factors making it difficult in diagnosis, treatment and prediction of prognosis. One of the causes of open bite is abnormal size and shape of the tongue. Macroglossia, a condition in which tongue is oversized, is caused by several factors which are not clearly identifiable, and it may be a major factor of anterior and posterior open bite. Macroglossia is subdivided into true, functional and pseudomacroglossia depending on its relative size in the oral cavity. In this case report, a patient was diagnosed as skeletal Class II with pseudomacroglossia, and was treated with SARPE in order to expand the narrowed maxillary arch and Quad helix for the mandibular arch. As a result the transverse deficiency was treated. In the adult patients where no skeletal growth is expected, SARPE has shown to be effective in treating maxillomandibular transverse discrepancies in which macroglossia was accompanied as in this case.

• Korean Journal of Applied Biomechanics
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• v.25 no.4
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• pp.489-498
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• 2015

Objective : The purpose of this study was to analyze the effects of the windlass mechanism in trail-walking shoe prototypes that can effectively support arches. A study of these effects should help with the development of a first-rate trail-walking shoe development guide for the distribution of quality information to consumers. Methods : The subjects were ten adult males who volunteered to participate in the study. Shoes from three companies, which will be referred to as Company S (Type A), Company M (Type B), and Company P (Type C), were selected for the experiment. The subjects wore these shoes and walked at a speed of 4.2 km/h, and as they tested each shoe, the contact area, maximum pressure average, and surface force were all measured. Results : Shoe Type A showed a contact area of $148.78{\pm}4.31cm^2$, Type B showed an area of $145.74{\pm}4.1cm^2$, and Type C showed an area of $143.37{\pm}4.57cm^2$ (p<.01). Shoe Type A demonstrated a maximum average pressure of $80.80{\pm}9.92kPa$, Type B an average of $85.72{\pm}11.01kPa$, and Type C an average of $89.12{\pm}10.88bkPa$ (p<.05). Shoe Type A showed a ground reaction force of $1.13{\pm}0.06%BW$, Type B a force of $1.16{\pm}0.04%BW$, and Type C a force of $1.16{\pm}0.03%BW$ (p<.05). Conclusion : The Type A trail-walking shoe, which was designed with a wide arch from the center of the forefoot to the front of the rearfoot showed excellent performance, however, more development and analysis of the windlass mechanism for a variety of arch structures is still necessary.