• Title/Summary/Keyword: anti-bias

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A Quantitative Study on How the Cheonghae Anti-piracy Unit influences the Occurrence of Maritime Piracy near Somalia (청해부대 파병(다국적 해군의 대(對)해적 작전)이 소말리아 인근 해적사건 발생에 미치는 영향에 관한 정량적연구)

  • Han, Jong-Hwan
    • Strategy21
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    • s.46
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    • pp.123-157
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    • 2020
  • This research focuses on one important type of non-traditional threat, maritime piracy, and tries to supplement previous research from the perspective of military power, especially naval power. When considering the elements of military power, naval power is a core independent variable to explain piracy incidents. Indeed, naval power can play a key role in solving piracy problems, since naval power is the only legitimate force to respond to piracy in the sea. It is natural that well equipped and trained naval power in the sea increases the probability of capturing pirates, which leads to increasing the costs of piracy and decreasing its occurrences. In addition, since naval combatant ships have more impressive weapons than those of pirate boats, just the presence of naval combatant ships could serve to deter piracy incidents in the sea. The main purpose of this research is finding the effectiveness of large multinational naval efforts to deter piracy incidents in Africa. With this research purpose, I analyze 771 piracy incidents that occurred in African states from 2009 to 2014. Furthermore, I include all 33 coastal states in Africa regardless of the experiences of piracy incidents in order to avoid selection bias, which is very common in quantitative-based piracy incidents research. The dependent variable of this research is frequency of maritime piracy incidents for a country-year and the independent variable is the number of multi-national naval warships that operate near Somalia. With this analysis, I find the large number of multi-state naval combatant ships are negatively related to piracy incidents. In other words, as a main means to counteract piracy incidents, multi-state naval combatant ships are conducive to reduce piracy incidents near Somalia, since it increases costs (being captured) of conducting piracy.

The Effects of Oral Administration of Deer Antler Extracts on an Osteoporosis-induced Animal Model: A Systematic Review and Meta-analysis (골다공증 유발 동물모델에서 녹용 추출물의 경구 투여 효과: 체계적 문헌고찰 및 메타분석)

  • Lee, Jung Min;Kim, Nam Hoon;Lee, Eun-Jung
    • Journal of Korean Medicine Rehabilitation
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    • v.32 no.2
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    • pp.65-81
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    • 2022
  • Objectives This study aimed to assess the effects of oral administration of deer antler extracts on an osteoporosis-induced animal model. We analyzed the results of using deer antler single extracts on animal models with osteoporosis through a systematic review and meta-analysis. Methods We included osteoporosis studies in animal experiments that administrated deer antler extracts orally. We searched the following 13 databases without a language restriction: PubMed, EMBASE, Cochrane Library, Cumulative Index to Nursing and Allied Health Literature (CINAHL), China National Knowledge Infrastructure (CNKI), Wanfang, Korean Medical Database (KMbase), National Digital Science Library (NDSL), Korean Traditional Knowledge (Koreantk), Oriental Medicine Advanced Searching Integrated System (OASIS), Research Information Sharing Service (RISS), Korea Institute of Science and Technology Information (KISTI), and Koreanstudies Information Service System (KISS). We used Systematic Review Centre for Laboratory Animal Experimentation's risk of bias tool for assessing the methodological quality of the included studies. Results A total of 299 potentially relevant studies were searched and 11 were included for a systematic review. Nine studies used a single deer antler extract. A study compared the effects of single extracts of deer antler and antler glue, while another study compared the effects of three single extracts of deer antler, old antler, and antler glue. For evaluating the intervention effect, bone mineral density (BMD) was measured as the primary outcome, while the histomorphometric indicators of the bone and serum alkaline phosphatase and osteocalcin levels were used as the secondary outcome variables. On conducting a meta-analysis of studies on single deer antler extract, BMD was observed to be significantly increased compared to that in control group (standardized mean difference [SMD]=2.11; 95% confidence interval [CI]=1.58~2.65; Z=7.75; p<0.00001; I2=56%). As a result of meta-analysis, according to the concentration of deer antler, the group with high concentration showed statistically significantly higher BMD than the group with low concentration (SMD=1.28; 95% CI=0.74~1.82; Z=4.63; p<0.00001; I2=9%). Conclusions The research shows that the deer antler extracts have significant anti-osteoporotic effects on the osteoporosis-induced animal model. However the studies included in this research had a high methodological risk of bias. This indicates the requirement of considerable attention in the interpretation of the study results.

Can different agents reduce the damage caused by bleaching gel to pulp tissue? A systematic review of basic research

  • Leticia Aparecida Silva Batista;Alexandre Henrique dos Reis-Prado;Hebertt Gonzaga dos Santos Chaves;Lara Cancella de Arantes;Luis Fernando Santos Alves Morgan;Carolina Bosso Andre;Thais Yumi Suzuki;Francine Benetti
    • Restorative Dentistry and Endodontics
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    • v.48 no.4
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    • pp.39.1-39.23
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    • 2023
  • Objectives: This study aimed to investigate the effectiveness of different topical/systemic agents in reducing the damage caused by bleaching gel to pulp tissue or cells. Materials and Methods: Electronic searches were performed in July 2023. In vivo and in vitro studies evaluating the effects of different topical or systemic agents on pulp inflammation or cytotoxicity after exposure to bleaching agents were included. The risk of bias was assessed. Results: Out of 1,112 articles, 27 were included. Nine animal studies evaluated remineralizing/anti-inflammatories agents in rat molars subjected to bleaching with 35%-38% hydrogen peroxide (HP). Five of these studies demonstrated a significant reduction in inflammation caused by HP when combined with bioglass or MI Paste Plus (GC America), or following KF-desensitizing or Otosporin treatment (n = 3). However, orally administered drugs did not reduce pulp inflammation (n = 4). Cytotoxicity (n = 17) was primarily assessed using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay on human dental pulp cells and mouse dental papilla Cell-23 cells. Certain substances, including sodium ascorbate, butein, manganese chloride, and peroxidase, were found to reduce cytotoxicity, particularly when applied prior to bleaching. The risk of bias was high in animal studies and low in laboratory studies. Conclusions: Few in vivo studies have evaluated agents to reduce the damage caused by bleaching gel to pulp tissue. Within the limitations of these studies, it was found that topical agents were effective in reducing pulp inflammation in animals and cytotoxicity. Further analyses with human pulp are required to substantiate these findings.

Pharmacoacupuncture for the Treatment of Frozen Shoulder: protocol for a systematic review and meta-analysis

  • Ji-Ho Lee;Hyeon-Sun Park;Sang-Hyeon Park;Dong-Ho Keum;Seo-Hyun Park
    • Journal of Pharmacopuncture
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    • v.27 no.1
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    • pp.14-20
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    • 2024
  • Objectives: Frozen shoulder (FS) is one of the most challenging shoulder disorders for patients and clinicians. Its symptoms mainly include any combination of stiffness, nocturnal pain, and limitation of active and passive glenohumeral joint movement. Conventional treatment options for FS are physical therapy, nonsteroidal anti-inflammatory drugs, injection therapy, and arthroscopic capsular release, but adverse and limited effects continue to present problems. As a result, pharmacoacupuncture (PA) is getting attention as an alternative therapy for patients with FS. PA is a new form of acupuncture treatment in traditional Korean medicine (TKM) that is mainly used for musculoskeletal diseases. It has similarity and specificity compared to corticosteroid injection and hydrodilatation, making it a potential alternative injection therapy for FS. However, no systematic reviews investigating the utilization of PA for FS have been published. Therefore, this review aims to standardize the clinical use of PA for FS and validate its therapeutic effect. Methods: The protocol was registered in Prospero (CRD42023445708) on 18 July 2023. Until Aug. 31, 2023, seven electronic databases will be searched for randomized controlled trials of PA for FS. Authors will be contacted, and manual searches will also be performed. Two reviewers will independently screen and collect data from retrieved articles according to predefined criteria. The primary outcome will be pain intensity, and secondary outcomes will be effective rate, Constant-Murley Score, Shoulder Pain and Disability Index, range of motion, quality of life, and adverse events. Bias and quality of the included trials will be assessed using the Cochrane handbook's risk-of-bias tool for randomized trials. Meta analyses will be conducted using Review Manager V.5.3 software. GRADE will be used to evaluate the level of evidence for each outcome. Results: This systematic review and meta-analysis will be conducted following PRISMA statement. The results will be published in a peer-reviewed journal. Conclusion: This review will provide scientific evidence to support health insurance policy as well as the standardization of PA in clinical practice.

Bias in TV News Coverage of President Park's Impeachment -Focusing on MBC and JTBC Evening News- (박근혜 대통령 탄핵 보도 편향성에 관한 연구 -MBC와 JTBC의 저녁종합뉴스를 중심으로-)

  • Kim, Byoung Jin;Lee, Sang Eun;Yang, Jong Hoon
    • The Journal of the Korea Contents Association
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    • v.17 no.11
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    • pp.554-566
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    • 2017
  • Through the Broadcasting Act, Republic of Korea regulates the broadcasting system to remain neutral regarding particular party or candidate. However, as MBC and JTBC reports the issue of President Park's impeachment in bisected way - conservative and progressive - the controversy aroused. This research paper comparatively analyzed each broadcasting company's evening news by focusing on quantity aspect, reporting tendency regarding trend of public opinion and mass rally and the news frame. Our research showed that both JTBC and MBC had partially reported; JTBC on pro-impeachment rally's side which was called candlelight rally, and MBC on anti-impeachment rally's side, called Korean National Flag rally. Regarding the way how they reported the impeachment, JTBC reported much more in depth than MBC, and MBC reported the process emotionally, standing for President Park.

A Systemic Review of Clinical Trials Using Medication for Acute Bronchitis: A Pre-study on the Development of Traditional Korean Medicine Clinical Practice Guideline (급성기관지염의 약물중재 임상시험에 대한 체계적 문헌 고찰: 임상시험 가이드라인 개발을 위한 예비연구)

  • Lyu, YeeRan;Park, So jung;Lee, Eun Jung;Jeon, Ju Hyun;Jung, In Chul;Park, Yang Chun
    • The Journal of Korean Medicine
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    • v.38 no.1
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    • pp.93-111
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    • 2017
  • Objectives: The aim of this study is to make evidence-based data for developing a traditional Korean medicine clinical practice guideline for acute bronchitis. Methods: We searched 3 international databases(PubMed, EMBASE, CENTRAL) and 7 domestic databases (KoreaMed, Kmbase, NDSL, KISS, KISTI, OASIS, KoreaTK) to identify randomized controlled trials (RCTs) of acute bronchitis using medicine in recent 10 years. The chosen trials were analyzed by their study design, age range, intervention group, control group, primary and second outcome measure, inclusion and exclusion of participants and adverse events. Results: 15 RCTs are finally included in this study and most of their medications are herbal medicine. For diagnosis and outcome measure of acute bronchitis, Bronchitis Severity Score(BSS) was mostly used. Other measurements eligible are coughing fits, quality of life scale, sputum viscosity, change of individual symptoms and patient's satisfaction. Test duration was for average 7days and safety assessment was held by recording adverse events. Except for anti-inflammatory and antibiotic trials, all medications are found to be effective and well-tolerated. General risk of bias of chosen trials is evaluated low. Conclusions: A well designed clinical trials for traditional Korean medicine of acute bronchitis is needed and this study is expected to make it available.

Bit-Rate Analysis of Various Symmetric ESQWs SEED under Optimized Input Power (최적 입사 광 전력 하에서의 대칭 ESQWs SEED의 비트 전송률 특성 분석)

  • Lim, Youn-Sup;Choi, Young-Wan
    • Journal of the Korean Institute of Telematics and Electronics D
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    • v.36D no.7
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    • pp.66-79
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    • 1999
  • We investigate the effects of high input power on the performance of optical bistable symmetric self-electooptic effect devices (S-SEEDs) using extremely shallow quantum wells (ESQWs). In this study, we consider the four ESQWs SEEDs; anti-reflection (AR)-coated ESQWs S-SEED, back-to-back AR coated ESQWs S-SEED, asymmetric F뮤교-Perot (AFP) ESQWs S-SEED, and back-to-back AFP-ESQWs S-SEED. As the input power increases, device performances such as on/off contrast ratio, on/off reflectivity difference are seriously degraded because of ohmic heating and exciton saturation. On the other hand, switching speed of the device increases up to certain value and then begins to decrease. With reasonable optimization of the input power for the best switching speed operation of the devices in a cascading optical interconnection system, we simulate and analyze the system bit-rate of the various ESQWs S-SEEDs, for a mesa of $5{\times}5{\mu}m^2$ size, changing the namber of quantum wells for the external bias of 0 V and -5V.

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A Study on the Design of Dual-Band Mixer for WLAN 802.11a/b/g Applications (802.11a/b/g WLAN용 이중대역 혼합기 설계에 관한 연구)

  • Park Wook-Ki;Go Min-Ho;Kang Suk-Youb;Park Hyo-Dal
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.16 no.11 s.102
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    • pp.1106-1113
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    • 2005
  • This paper presents a dual-band mixer for multi-standards of IEEE 802.1la/b/g using a single local oscillator, so as to improve the defects of legacy systems. Those systems have duplicate local oscillators and mixers to handle dual band signals, increasing complexity of system and power loss. The proposed circuit shows 11.6 dB, 16.8 dB of conversion loss and 8.77 dBm, 12.5 dBm of IIP3(Input 3rd Intercept Point) for respective bands when the two RF inputs of 2.452 and 5.260 GHz are down-converted to the identical 356 MHz If frequency. The RF-LO isolations are measured 36 dB, 41 dB at each frequencies and over 50 dB of LO-IF isolations are achieved at all cases.

Electroacupuncture for Treatment of Polycystic Ovarian Syndrome: Systematic Review of Randomized Controlled Trials (다낭성 난소증후군의 전침 치료 연구에 관한 체계적 문헌 고찰)

  • Yoon, Jun-Geol;Park, Nam-Chun;Ji, Hae-Ri;Park, Kyoung-Sun;Hwang, Deok-Sang;Lee, Jin-Moo;Lee, Chang-Hoon;Jang, Jun-Bock
    • The Journal of Korean Obstetrics and Gynecology
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    • v.31 no.4
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    • pp.39-53
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    • 2018
  • Objectives: The purpose of this review was to overview and evaluate the efficacy of electroacupunture for women with polycystic ovarian syndrome (PCOS) Methods: Relevant randomized controlled studies (RCTs) were identified by database searches in PubMED, EMBASE, OASIS, and Google scholar, up to May 2018. Data were extracted regarding hyperandrogenism, obesity and hyperinsulinemia indices. The risk of bias was assessed. Results: Five RCTs were included for analysis. In one RCT, electroacupuncture group had significantly lower free testosterone and testosterone, compared to no treatment group. However, The other RCTs showed no significant difference between two groups. For LH/FSH, Ferriman Gallway score, anti-mullerian hormone, body mass index, weight and waist, and insulin, electroacupuncture group showed no significant difference, compared to physical exercise, no treatment, and sham acupuncture group. Conclusions: Only a limited number of RCTs have been reported. At present, there is insufficient evidence to support the use of electroacupuncture for treatment of PCOS.

Derivation of Geostationary Satellite Based Background Temperature and Its Validation with Ground Observation and Geographic Information (정지궤도 기상위성 기반의 지표면 배경온도장 구축 및 지상관측과 지리정보를 활용한 정확도 분석)

  • Choi, Dae Sung;Kim, Jae Hwan;Park, Hyungmin
    • Korean Journal of Remote Sensing
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    • v.31 no.6
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    • pp.583-598
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    • 2015
  • This paper presents derivation of background temperature from geostationary satellite and its validation based on ground measurements and Geographic Information System (GIS) for future use in weather and surface heat variability. This study only focuses on daily and monthly brightness temperature in 2012. From the analysis of COMS Meteorological Data Processing System (CMDPS) data, we have found an error in cloud distribution of model, which used as a background temperature field, and in examining the spatial homogeneity. Excessive cloudy pixels were reconstructed by statistical reanalysis based on consistency of temperature measurement. The derived Brightness temperature has correlation of 0.95, bias of 0.66 K and RMSE of 4.88 K with ground station measurements. The relation between brightness temperature and both elevation and vegetated land cover were highly anti-correlated during warm season and daytime, but marginally correlated during cold season and nighttime. This result suggests that time varying emissivity data is required to derive land surface temperature.