• Journal of the Korean Applied Science and Technology
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• v.37 no.6
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• pp.1528-1534
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• 2020

This study examines the trends of the domestic age-friendly industry, examines the ingredients notified by the Ministry of Food and Drug Safety of aging cosmetics, and analyzes the research trends of raw materials other than the notices, and prepares data for the aged-friendly industry to quickly cope with changes in the cosmetics industry environment and aging people. I wanted to. In addition to the ingredients notified by the Ministry of Food and Drug Safety, research trends on the development of ingredients for anti-aging cosmetics are examined, and the anti-aging effects of each ingredient are examined. Through this, 'aging' and 'cosmetics', 'Anti-Aging', 'Anti-Aging', etc. In order to lead the development of anti-aging cosmetics related to the aging industry, research activities on products that are effective in preventing aging by strengthening the skin in addition to the four ingredients notified by the Ministry of Food and Drug Safety are constantly being conducted. In the functional cosmetics field notified by the Minister of Food and Drug Safety, it is believed that various basic research activities should be conducted so that research on anti-aging can be scientifically supported rather than a single research.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.30 no.4 s.48
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• pp.445-448
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• 2004

Aging is divided into intrinsic aging and photo-aging. Intrinsic aging is naturally occurred as the time passed and photo-aging is induced by the UV radiation of skin. The main reason of aging is the free radicals and the degeneration of the cellular materials by free radicals. In this paper, we checked the anti-aging effects of Mallotus japonicus bark extracts. It has the ability to scavenge free radicals and the SOD like activity. Also, it reduced the cell damage by hydrogen peroxide treatment. Mallotus japonicus bark extracts showed the excellent activity on inhibiting the UV induced cell damage and DNA damage. In conclusion, Mallotus japonicus bark extracts can be used as active ingredients for anti-aging cosmetics.

• The Korea Journal of Herbology
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• v.22 no.4
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• pp.219-225
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• 2007

Objectives : We investigated the anti-aging effects on skin with Saccharomyces fermented modified Kyungohkgo extract (SFKE). Methods : Fermented modified Kyungohkgo extracts by 14 different kinds of microorganism were prepared and most effective Saccharomyces fermented modified Kyungohkgo extract among these was selected for anti-aging agent. We measured various effects related to skin such as scavenging activity against free radical, cell proliferation, collagen synthesis and toxicity of SFKE were evaluated and compared with modified Kyungohkgo extract (KE). Results : Free-radical scavenging activity and cell proliferating ratio of SFKE were 2 and 8 times higher than those of KE. The SFKE could significantly increase the collagen synthetic ratio compared with KE treated group. SFKE showed no toxicity at all tested concentrations. Conclusions : The results of our study propose that SFKE have good anti-aging effects on skin.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.32 no.2 s.57
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• pp.69-74
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• 2006

Selaginella tamariscina with the popular Korean name Keoun Back, is a traditional medicinal plant for therapy of advanced cancer patients in the Orient. In this study, we evaluated anti-aging activity of S. tamariscina using processed technology and investigated diverse biological activities of processed S. tamariscina (PST) as an anti-aging ingredient of cosmetics. PST, heated with sand, used to different purpose compared with origin in medicine. PST raises total phenol concentration and enhances the DPPH radical scavenging activity. For testing intracellular ROS scavenging activity, the cultured human dermal fibroblasts were analyzed by increase in dichlorofluorescein (DCF) fluorescence upon exposure to UVB $20 mJ/cm^2$ after treatment of PST. UVA-induced MMP-1 expression in human dermal fibroblasts was reduced in a dose-dependent manner by PST. Taken together, 4hese results suggest that PST may act as an anti-aging agent by preventing the skin cell from damage induced by UV irradiation, and imply that PST may be useful as a new ingredient for anti-aging cosmetics.

• Journal of Convergence for Information Technology
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• v.11 no.6
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• pp.181-187
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• 2021

As the aging society progresses and the functional cosmetics market is revitalized we have learned that the functional cosmetics that the silver generation is most interested in are wrinkle-improving products and we are making great efforts to develop functional cosmetics that improve wrinkles. The ingredients are actually making. From the early 2000s when the development of functional cosmetics began to the present the research trends of functional cosmetics for wrinkle improvement were analyzed by analyzing papers on functional cosmetics for wrinkle improvement. Research methods focused on literature search and SIRS paper search keywords. And the cosmetic material that needs to be researched focuses on the anti-aging function among functional cosmetics which is the anti-wrinkle function. The research results show the rapid growth of the Anti-aging market. As the population ages the generation of silver with high purchasing power will expand and a market for expensive anti-aging products and services for a healthy old age will be formed.

• Korean Journal of Pharmacognosy
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• v.50 no.4
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• pp.285-290
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• 2019

This study was carried out to identify the skin anti-aging effect of cycloheterophyllin on dermal fibroblasts. To elucidate anti-aging effects of cycloheterophyllin on dermal fibroblasts, I measured cell viability, mRNA expressions, and Collagen, type I/matrix metallopeptidase 1(MMP1)-ELISA assay. In this study, I investigated the effects of cycloheterophyllin on Collagen, type I, alpha 1(COL1A1)/Collagen, type III, alpha 1(COL3A1)/MMP1/Superoxide dismutases/Catalase(CAT) mRNA expressions and Collagen, type I/MMP1 protein production. Quantitative Real-time RT-PCR showed that cycloheterophyllin increased mRNA level of COL1A1/COL3A1/CAT genes and collagen, type I protein by ELISA assay compared to UVA-treated dermal fibroblasts. Furthermore MMP1 mRNA and protein expressions were decreased by cycloheterophyllin treatment. These observations revealed that cycloheterophyllin increased anti-aging effects in dermal fibroblasts. Therefore, I identified the anti-aging effects of cycloheterophyllin, and these results showed that the cycloheterophyllin can be a considerable potent ingredient for skin anti-aging. Based on this, I anticipated further researches about cycloheterophyllin for mechanism to develop not only cosmetics but for healthcare food or medicine.

• KSBB Journal
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• v.31 no.3
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• pp.178-185
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• 2016

Aging of the face is mainly related to the features that are sagging or loss of elasticity of the skin by reducing the volume around the eyes or cheek. Intrinsic aging can be seen to cause thinner dermis, reduction of extracellular matrix and subcutaneous fat. This study was carried out to investigate the skin volume augmentation and anti-wrinkle effects of Tribulus terrestris fruit extract. Skin anti-aging effect of Tribulus terrestris fruit extract was evaluated by using lipid accumulation, expressin of type I procollagen and elastin in preadipocytes and human dermal fibroblasts. Tribulus terrestris fruit extract augmented preadipocytes differentiation about 56% at 100 µg/mL. The type I procollagen and elastin were increased about 35% and 25% by treatment 20% Tribulus terrestris fruit extract, respectively. The clinical study also showed that skin sagging, skin elasticity, and dermal density improved without adverse effect following 4 week application of cream containing 2% Tribulus terrestris fruit extract. We suggest that Tribulus terrestris fruit extract can have the good possibility as skin volume augmenting, skin elasticity and wrinkle improving agent.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.24 no.3
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• pp.24-30
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• 1998

Inhibitory effects of the new material obtained from Areca catechu seed (CC-516) according to a special process, and its applicability to the skin as a cosmetic raw material in terms of its efficacy were presented. Areca catechu extract out of 150 medicinal plants, exhibited high inhibitory effect on the porcine pancreatic elastase ($IC_{50}$ : $40.8{\mu}$g/ml). It also had an inhibitory effect on the human leukocyte elastase ($IC_{50}$ : 48.1$\mu$g/ml), hyaluronidase ($IC_{50}$ : $416{\mu}$g/ml), antioxidative activity ($IC_{50}$ : $45.4\mu$g/ml) and free radical scavenging activity ($SC_{50}$ : $10.2{\mu}$g/ml). The cream contained 3％ of CC-516 improved skin hydration above 16.5％. Especially, the skin elasticity increases more than 35% and skin wrinkles decreased more than 23％. The CC-516 was designed to be utilized in cosmetology. The cream containing 3％ of this product has not only protecting effect on the skin mechanical properties provided by the collagen and the elastin in the derm but also restructuring effect of scarring or aging tissue.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.44 no.2
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• pp.103-110
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• 2018

To develop a new functional agent for cosmetics, we investigated the anti-aging activities in fibroblasts using sweroside isolated from Nymphoides indica. The anti-aging effect of sweroside was validated in CCD-986sk cells. Results showed that sweroside inhibited expressions of UVB-induced ROS and increased pro-collagen. Furthermore, sweroside had inhibited MMP-1 expression. Taken together, the results suggested that sweroside has considerable potential as a new cosmetics ingredient with an anti-aging effect.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.33 no.1 s.60
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• pp.33-40
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• 2007

Astradalus membranaceus root extract (ARE) contains saponins, flavonoids, and their glycosides. Two flavonoids, calycosin and formononetin, were predominant constituents with the different amount by diverse extraction conditions. ARE showed the anti-oxidative activities, inhibited tyrosinase activity, and increased type I procollagen expression in proportion to calycosin and formononetin contents. The clinical study also showed that skin wrinkles were significantly reduced in the test group treated with a cream formulation containging 0.1% ARE compared with a group treated with a cream formulation without 0.1% ARE (p < 0.05). These results suggest that ARE may have potential as an anti-aging ingredient in cosmetics.