• Title/Summary/Keyword: ang Seong Ji

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Functional Implications of the Conserved Action of Regulators of Ribonuclease Activity

  • Yeom, Ji-Hyun;Shin, Eun-Kyoung;Go, Ha-Young;Sim, Se-Hoon;Seong, Maeng-Je;Lee, Kang-Seok
    • Journal of Microbiology and Biotechnology
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    • v.18 no.8
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    • pp.1353-1356
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    • 2008
  • RNase E (Rne) plays a major role in the decay and processing of numerous RNAs in E. coli, and protein inhibitors of RNase E, RraA and RraB, have recently been discovered. Here, we report that coexpression of RraA or RraB reduces the ribonucleolytic activity in rne-deleted E. coli cells overproducing RNase ES, a Streptomyces coelicolor functional ortholog of RNase E, and consequently rescues these cells from growth arrest. These findings suggest that the regulators of ribonuclease activity have a conserved intrinsic property that effectively acts on an RNase E-like enzyme found in a distantly related bacterial species.

Functional Polymers for Drug Delivery Systems in Nanomedicines

  • Lee, Eun-Seong;Kim, Ji-Hoon;Yun, Jeong-Min;Lee, Kyung-Soo;Park, Ga-Young;Lee, Beom-Jin;Oh, Kyung-Taek
    • Journal of Pharmaceutical Investigation
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    • v.40 no.spc
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    • pp.45-61
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    • 2010
  • Polymeric based nanomedicines have been developed for diagnosing, treating, and preventing diseases in human body. The nanosized drug delivery systems having various structures such as micelles, nanogels, drug-conjugates, and polyplex were investigated for a great goal in pharmaceutics: increasing therapeutic efficacy for diseases and decreasing drug toxicity for normal tissues. The functional polymers used for constituting these drug delivery systems should have several favorable properties such as stimuli-responsibility and biodegrdability for controlled drug release, and solublization capacity for programmed drug encapsulation. This review discusses recent developments and trends of functional polymers (e.g., pH-sensitive polymers, biodegradable polymers, and cationic polymers) used for nanosized drug carriers.

A Switch Wrapper Design for an AMBA AXI On-Chip-Network (AMBA AHB와 AXI간 연동을 위한 Switch Wrapper의 설계)

  • Yi, Jong-Su;Chang, Ji-Ho;Lee, Ho-Young;Kim, Jun-Seong
    • Proceedings of the IEEK Conference
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    • 2005.11a
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    • pp.869-872
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    • 2005
  • In this paper we present a switch wrapper for an AMBA AXI, which is an efficient on-chip-network interface compared to bus-based interfaces in a multiprocessor SoC. The AXI uses an idea of NoC to provide the increasing demands on communication bandwidth within a single chip. A switch wrapper for AXI is located between a interconnection network and two IPs connecting them together. It carries out a mode of routing to interconnection network and executes protocol conversions to provide compatibility in IP reuse. A switch wrapper consists of a direct router, AHB-AXI converters, interface modules and a controller modules. We propose the design of a all-in-one type switch wrapper.

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Short Research For Sunfull Automation Bot (선플 자동화 봇에 관한 짧은 연구)

  • Kim, YongJun;Kwon, Soonwoo;Oh, YoungEun;Park, TaeHyun;Seong, Hoon;Lee, JiSu;Kang, Yunjeong
    • Proceedings of the Korean Society of Computer Information Conference
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    • 2017.07a
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    • pp.291-292
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    • 2017
  • 우울증은 매우 보편적인 정신병이다. 보건복지부에 따르면 지난해 우리나라 우울증 환자는 61만 3000명으로 전체 국민의 1.5%를 차지했다. 그러나 대부분의 환자들은 본인이 우울증인지도 모르거나 정신병원 진료 기록이 남는다는 이유로 치료를 거부하여 상태를 악화시키는 경우가 적잖다. 그럴 때 다른 이의 도움이 필요하나 정신적인 질환은 겉으로 봐서는 알아차리기가 어렵고 폐쇄적인 우울증 환자의 특성상 직접 만나는 등의 물리적인 도움을 주기는 많이 어려운 것이 사실이다. 그래서 우리는 인터넷이라는, 가장 광범위하고 가장 긴밀한 플랫폼을 통하여 이런 우울증 환자들에게 다가가고자 '선플 로봇'을 고안하게 되었다.

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