• Journal of Ginseng Research
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• v.46 no.3
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• pp.464-472
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• 2022

Background: Gut microbiota influence the central nervous system through gut-brain-axis. They also affect the neurological disorders. Gut microbiota differs in patients with Alzheimer's disease (AD), as a potential factor that leads to progression of AD. Oral intake of Korean Red Ginseng (KRG) improves the cognitive functions. Therefore, it can be proposed that KRG affect the microbiota on the gut-brain-axis to the brain. Methods: Tg2576 were used for the experimental model of AD. They were divided into four groups: wild type (n = 6), AD mice (n = 6), AD mice with 30 mg/kg/day (n = 6) or 100 mg/kg/day (n = 6) of KRG. Following two weeks, changes in gut microbiota were analyzed by Illumina HiSeq4000 platform 16S gene sequencing. Microglial activation were evaluated by quantitative Western blot analyses of Iba-1 protein. Claudin-5, occludin, laminin and CD13 assay were conducted for Blood-brain barrier (BBB) integrity. Amyloid beta (Aβ) accumulation demonstrated through Aβ 42/40 ratio was accessed by ELISA, and cognition were monitored by Novel object location test. Results: KRG improved the cognitive behavior of mice (30 mg/kg/day p < 0.05; 100 mg/kg/day p < 0.01), and decreased Aβ 42/40 ratio (p < 0.01) indicating reduced Aβ accumulation. Increased Iba-1 (p < 0.001) for reduced microglial activation, and upregulation of Claudin-5 (p < 0.05) for decreased BBB permeability were shown. In particular, diversity of gut microbiota was altered (30 mg/kg/day q-value<0.05), showing increased population of Lactobacillus species. (30 mg/kg/day 411%; 100 mg/kg/day 1040%). Conclusions: KRG administration showed the Lactobacillus dominance in the gut microbiota. Improvement of AD pathology by KRG can be medicated through gut-brain axis in mice model of AD.

• Korean Journal of Remote Sensing
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• v.39 no.5_3
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• pp.967-978
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• 2023

This study proposed and validated a combined segmentation network (CSN) designed to effectively train on multiple drone image datasets and enhance the accuracy of semantic segmentation. CSN shares the entire encoding domain to accommodate the diversity of three drone datasets, while the decoding domains are trained independently. During training, the segmentation accuracy of CSN was lower compared to U-Net and the pyramid scene parsing network (PSPNet) on single datasets because it considers loss values for all dataset simultaneously. However, when applied to domestic autonomous drone images, CSN demonstrated the ability to classify pixels into appropriate classes without requiring additional training, outperforming PSPNet. This research suggests that CSN can serve as a valuable tool for effectively training on diverse drone image datasets and improving object recognition accuracy in new regions.

• Spatial Information Research
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• v.20 no.2
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• pp.137-153
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• 2012

Until now, many indexing methods that can reduce update cost have been proposed for managing massive moving objects. Because indexing methods for moving objects have to be updated periodically for managing moving objects that change their location data frequently. However these kinds indexing methods occur big load that exceed system capacity when the number of moving objects increase dramatically. In this paper, we propose the update frequency reducing method to combine MapReduce and existing indices. We use the update request grouping method for each moving object by using MapReduce. We decide to update by comparing the latest data and the oldest data in grouping data. We reduce update frequency by updating the latest data only. When update is delayed, for the data should not be lost and updated periodically, we store the data in a certain period of time in the hash table that keep previous update data. By the performance evaluation, we can prove that the proposed method reduces the update frequency by comparison with methods that are not applied the proposed method.

• Journal of the Korean Society for Nondestructive Testing
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• v.31 no.2
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• pp.139-143
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• 2011

The problem of delamination of composite tubes by impact has been acknowledged in aerospace and automobile industry. Non-destructive testing(NDT) methods in composite material structure are important to evaluate reliability of composite structure. There are many kinds of NDT methods which can detect the inside defect of the composite material such as Infrared Thermography(IRT). Infrared thermal imaging of object is different from that of a defect, in heated composite tubes with an internal defect, and then location and size of a defect can be measured by the analysis of thermal imaging pattern. In this study, Lock-in Infrared thermography detect internal defects of Impacted composite tubes by the inspection of infrared lay radiated from the surface of composite tubes.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.10 no.2
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• pp.173-178
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• 2010

Recently, Technical innovation has been implemented in a broad variety of industry fields to reach an ubiquitous society, with the object of popularizing u-Hospital, the mobile technology with no restriction to the place tends to be used positively in Health care fields. The existing mobile medical reservation system has the problem of not making good use of location information of users due to the interface based on text in the existing web pages. This paper proposes an mobile medical reservation system using geographic information service to solve the problems of current reservation system by using RIA(Rich Internet Application) technology applicable to Web 2.0 environment. Our proposed system also does the all required processes in a few page view, gets the differentiated service from the existing system by allowing efficient data exchange using XML, and expects the improvement of user friendliness by flexible user interface.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.25 no.10
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• pp.1346-1354
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• 2001

The heat transfer characteristics off swirling air jet impinging on a heated flat plate have been investigated experimentally. The main object is to enhance the heat transfer rate by increasing turbulence intensity of impinging jet with a specially designed swirl generator. The mean velocity and turbulent intensity profiles of swirling jet were measured using a hot-wire anemomety. The temperature distribution on the heated flat surface was measured with thermocouples. As a result the swirl effect on the local heat transfer rate on the impinging plate is confined mainly in the small nozzle-to-plate spacings such as L/D<3 at the stagnation region. For small nozzle-to-plate spacings, the local heat transfer in the stagnation region is enhanced from the increased turbulence intensity due to swirl motion, compared with the conventional axisymmetric impinging jet without swirl. For example, the local Nusselt number of swirling jet with swirl number Sw=0.75 and Sw=1 is about 9.7-76% higher than that of conventional impinging jet at the radial location of R/D=0.5. With the increase of the nozzle-to-plate distance, the stagnation heat transfer rate is decreased due to the diminishing axial momentum of the swirling jet. However, the swirling impinging jet for all nozzle-to-plate spacings tested in this study does not enhance the average heat transfer rate.

• Journal of the Korea Society of Computer and Information
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• v.16 no.7
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• pp.25-34
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• 2011

In this paper, we propose a new golf putting training system which we call "X-Putt". X-Putt analyzes putting strokes by measuring putter face angle and path. To do this, we improved the sonar-based localization scheme used by previous localization techniques. As a result, X-Putt can measure putter's location within the error range, ${\pm}0.9cm$ and putter face angle within ${\pm}1.5^{\circ}$. Additionally, we built an user application that has an easy-to-use interface for analyzing the strokes after training.

• Journal of the Health Care and Life Science
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• v.9 no.2
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• pp.297-302
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• 2021

As the price of LiDAR developed for autonomous driving has dropped dramatically, LiDAR has begun to be applied in various fields. Typical examples are vacuum cleaner robots, autonomous delivery robots, and autonomous obstacle avoidance drones. LiDAR is becoming the only means of figuring out the location of an object in real time while compensating for the weakness that 2D or 3D cameras are vulnerable to lighting. In this paper, we propose a method to monitor the movement of a patient by installing a 2D lidar in a hospital room. When a patient who needs intensive monitoring due to psychologically unstable, suicidal intention, or psychotic findings is alone in the ward, 2D LiDAR monitors the patient's movement and sends an appropriate alarm to the management room to effectively monitor the patient. devised a way to do it.

• Journal of Cadastre & Land InformatiX
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• v.48 no.1
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• pp.139-151
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• 2018

The National Base Map construction consists of the regular correction work of dividing the whole country into two regions and carrying out the modification Plotting by aerial photographs every two years as well as the real time updating work of correcting the major change feature within two weeks by the field survey and the As-Built Drawing. In the case of the Building Layout Drawing of Korea Real estate Administration intelligence System(KRAS) used for real time updating work of the National base map, the coordinate transformation error is included in the positional error when applied to the National Base Map based on the World Geodetic Reference System as the coordinate system based on the Regional Geodetic Reference System. In addition, National Base Map is registered based on the outline(eaves line) of the building in the Digital Topographic Map, and the Cadastral and Architecture are registered based on the building center line. Therefore, the Building Object management standard is inconsistent. In order to investigate the improvement method, the network RTK survey was conducted directly on a location of the Building Layout Drawing of Korea Real estate Administration intelligence System(KRAS) and the problems were analyzed by comparing with the plane plotting position reference in National Base Map. In the case of the general structure with the difference on the Building center line and the eaves line, beside the location information was different also the difference in the ratio of the building object was different between Building center line and the eave. In conclusion, it is necessary to provide the Base data of the double layer of the Building center line and the outline of the building(eaves line) in order to utilize the Building Layout Drawing of Korea Real estate Administration intelligence System(KRAS). In addition, it is necessary to study an organic map update process that can acquire the up-to-dateness and the accuracy at the same time.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.24 no.6
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• pp.675-683
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• 2011

When impacts by falling objects are applied to the structures, vertical resisting member(column or column group) results in progressive collapse. By knowing clearly load-deformation relationship of a structural frame, to prevent progressive collapse by absorbing potential energy of falling objects though column groups are lost by the impact of falling object accidently. If residual strength in vertical direction exceeds vertical load, which the sum of the weight of falling objects and usual supportive vertical load as the result of absorbing released location energy, it does not result in progressive collapse. On the other hand, in case when weight of falling objects is included in usual supportive vertical load. In this paper, 1-story 4-spans model is analyzed by non-linear FEM and to examine the level of deterioration, limit analysis of 1-story 4-spans plane frame was carried out.