• Journal of Platform Technology
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• v.9 no.2
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• pp.38-45
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• 2021

A frequently used bioimpedance analytical method in Korea is the segmental multi-frequency BIA (SMF-BIA) method, but it is not directly determined at a segmented impedance. This study was to compare SMF-BIA determinations with direct segmented determinations for accuracy and appropriateness of segment parameters. This study is to compare the segment parameters, accuracy and appropriateness of the multi-frequency segmental bioimpedance analysis. To this end, 108 elderly individuals were measured. Segmented bioelectrical measurements obtained from a SMF-BIA (Inbody S10) at 50 kHz and measured with a phase sensitive single frequency device (SF-BIA, bia-101, RJL / akern systems) were compared. The significant difference (%) was demonstrated between single - and multiple frequency determinations of the right upper limb (R = 35.5 ± 6.2%, P < 0.001; Xc = 2.7 ± 7.6%, P < 0.01), left upper limb difference (R= 33. 9 ± 6.0%, P < 0.001; Xc = 2.8 ± 8.3%, P < 0.01), right lower limb difference (R = 18.6 ± 4.3%, P < 0.001; Xc = 25.8 ± 10.0%, P < 0.001), left lower limb difference (R = 18.0 ± 4.7%, P < 0.001; Xc = 31.8%). Of the results determined with the two BIA methods, the impedance measurements of the limbs and whole body showed a high correlation (RA: R = 0. 950, LA: R = 0. 949, RL: R = 0.899, LL: R = 0.88), and in the agreement test, the impedance values of the upper limbs and whole body also showed strong agreement (ICC > 0.9), but in the Xc, the correlation was weak. In conclusion, it was found that although bioimpedance devices had significantly different characteristics and inconsistent cross sectionally, there was a high population level agreement in the upper and lower extremities in determining segmental resistance value changes. But a large error was found on the trunk. Further studies were needed for reducing the error.

• Journal of Korea Water Resources Association
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• v.53 no.12
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• pp.1143-1157
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• 2020

In this study, a criteria for the SWAT model calibration method in SWAT-CUP which considers multi-site and multi-variable observations was presented. For its application, the SWAT model was simulated using long-term observed flow, soil moisture, and evapotranspiration data in Yongdam study watershed, investigating the hydrological runoff characteristics and water balance in the water cycle analysis. The model was calibrated with different parameter values for each sub-watershed in order to reflect the characteristics of multiple observations through one-by-one calibration, appropriate settings of model simulation run/iteration number (1,000 simulation runs in the first iteration and then 500 simulation runs for the following iterations), and executions of partial and all run in SWAT-CUP. The flow simulation results of watershed outlet point, ENS 0.85, R2 0.87, and PBIAS -7.6%, were compared with the analysis results (ENS 0.52, R2 0.54, and PBIAS -22.4%) applied in the other batch (i.e., non one-by-one) calibration approach and showed better performances of proposed method. From the simulation results of a total of 15 years, it was found that the total runoff (streamflow) and evapotranspiration rates from precipitation are 53 and 39%, and the ratio of surface runoff and baseflow (i.e., sum of lateral and return flow, and recharge deep aquifer) are 35 and 65%, respectively, in Yongdam watershed. In addition, the analytical amount of available water (i.e., water yield), including the total annual streamflow (daily average 21.8 m3/sec) is 6.96 billion m3 per year (about 540 to 900 mm for sub-watersheds).

• Journal of the Society of Cosmetic Scientists of Korea
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• v.48 no.4
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• pp.321-330
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• 2022

This study attempted to establish an optimal multi-compound simultaneous analysis method that can secure reliable results for 15 - preservatives, 2 - sun screens and 1 - antioxidants of cosmetics using HPLC-PDA. Since the potential of hydrogen (pH) in the mobile phase affects the acid dissociation constant (pKa) of the preservatives, and the peak retention time shift and area change were observed. The peak separation condition was established by adjusting the pH to 0.1% H₃PO₄ addition (mL) when preparing the mobile phase. As a results of method validation, the linearity correlation coefficient (R²) of above 0.999 were obtained, and accuracy 87.9 ~ 101.1%, 0.1 ~ 7.6% precision for two types of cosmetics (cream and shampoo). It was found that the limit of detection (LOD) was 0.1 ~ 0.2 mg/kg and the limit of quantitation (LOQ) was 2.0 ~ 4.0 mg/kg. In addition, it was possible to simultaneously separate p-anisic acid, a natural compound that was difficult to separate in HPLC due to the small difference from methylparaben, a synthetic preservatives. Through this study, it will be effectively used to secure quality control and safety for compound that need restrictions on use cosmetics.

• Proceedings of the Korean Society of Near Infrared Spectroscopy Conference
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• 2001.06a
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• pp.1615-1615
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• 2001

During the past ten years, Near Infrared Spectroscopy has been successfully applied to the analysis of a great variety of agriculture products. Previous works (Morra et al., 1991; Salgo et al., 1998) have shown the potential of this technology for soil analysis, estimating different parameters just with one single scan. The main advantages of NIR applications in soils are the speed of response, allowing the increase of the number of samples analysed to define a particular soil, and the instantaneous elaboration of recommendations for fertilization and soil amendment. Another advantage is to avoid the use of chemical reagents at all, being an environmentally safe technique. In this paper, we have studied a set of 129 soil samples selected from representative glasshouse soils from Southern Spain. The samples were dried, milled, and sieved to pass a 2 mm sieve and then analysed for organic carbon, total nitrogen, inorganic nitrogen (nitrate ammonium), hygroscopic humidity, pH and electrical conductivity in the 1:1 extract. NIR spectra of all samples were obtained in reflectance mode using a Foss NIR Systems 6500 spectrophotometer equipped with a spinning module. Calibration equations were developed for seven analytical parameters (ph, Total nitrogen, organic nitrogen, organic carbon, C/N ratio and Electric Conductivity). Preliminary results show good correlation coefficients and standard errors of cross validation in equations obtained for Organic Carbon, Organic Nitrogen, Total Nitrogen and C/N ratio. Calibrations for nitrates and nitrites, ammonia and electric conductivity were not acceptable. Calibration obtained for pH had an acceptable SECV, but the determination coefficient was found very poor probably due to the reduced range in reference values. Since the estimation of Organic Carbon and C/N ratio are acceptable NIIRS could be used as a fast method to assess the necessity of organic amendments in soils from Mediterranean regions where the low level of organic matter in soils constitutes an important agronomic problem. Furthermore, the possibility of a single and fast estimation of Total Nitrogen (tedious determination by modifications of the Kjeldahl procedure) could provide and interesting data to use in the estimation of nitrogen fertilizer rates by means of nitrogen balances.

• Journal of the Korea Society for Simulation
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• v.18 no.3
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• pp.103-112
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• 2009

In a nuclear power plant (NPP), periodic sensor calibrations are required to assure sensors are operating correctly. However, only a few faulty sensors are found to be calibrated. For the safe operation of an NPP and the reduction of unnecessary calibration, on-line calibration monitoring is needed. In this paper, principal component-based Auto-Associative support vector regression (PCSVR) was proposed for the sensor signal validation of the NPP. It utilizes the attractive merits of principal component analysis (PCA) for extracting predominant feature vectors and AASVR because it easily represents complicated processes that are difficult to model with analytical and mechanistic models. With the use of real plant startup data from the Kori Nuclear Power Plant Unit 3, SVR hyperparameters were optimized by the response surface methodology (RSM). Moreover the statistical techniques are integrated with PCSVR for the failure detection. The residuals between the estimated signals and the measured signals are tested by the Shewhart Control Chart, Exponentially Weighted Moving Average (EWMA), Cumulative Sum (CUSUM) and generalized likelihood ratio test (GLRT) to detect whether the sensors are failed or not. This study shows the GLRT can be a candidate for the detection of sensor drift.

• Korean Journal of Environmental Agriculture
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• v.42 no.3
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• pp.203-210
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• 2023

Ferimzone Z is a fungicide for effectively controlling rice blast. Under light irradiation conditions, it undergoes a rapid conversion to its E-stereoisomer. Given the importance of isomers in risk assessments of residues in crops, an analytical method was developed for individual isomer quantification. A comparative analysis performed using two columns in HPLC-MS/MS demonstrated that the isomers were successfully separated using the Cadenza column. For the brown rice sample preparation, 5 g of the homogenized sample was saturated with 7 mL of water. The sample was then extracted with a 10 mL mixed solvent of acetonitrile and ethyl acetate (1:1, v/v) that contained 0.1% formic acid, and it was subsequently partitioned with magnesium sulfate and sodium chloride. The upper layer was purified using dSPE containing C₁₈ and PSA sorbents. The established method was subjected to method validation, and it showed recovery rates of 90.6-98.8% (RSD ≤ 3.9%) at concentrations of 0.01, 0.1, 2 mg/kg, with a soft matrix effect (%ME) ranging from -3.1% to +6.5%. This method can be employed in monitoring studies of brown rice to determine the conversion ratio from the Z isomers to the E isomers.

• Korean Journal of Environmental Agriculture
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• v.42 no.1
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• pp.71-81
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• 2023

An accurate and easy-to-use analytical method for determining isocycloseram and its metabolites (SYN549431 and SYN548569) residue is necessary in various food matrixes. Additionally, this method should satisfy domestic and international guidelines (Ministry of Food and Drug Safety and Codex Alimentarius Commission CAC/GL 40). Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) was used to determine the isocycloseram and its metabolites residue in foods. To determine the residue and its metabolites, a sample was extracted with 20 mL of 0.1% formic acid in acetonitrile, 4 g magnesium sulfate anhydrous and 1 g sodium chloride and centrifuged (4,700 G, 10 min, 4℃). To remove the interferences and moisture, d-SPE cartridge was performed before LC-MS/MS analysis with C₁₈ column. To verify the method, a total of five agricultural commodities (hulled rice, potato, soybean, mandarin, and red pepper) were used as a representative group. The matrix-matched calibration curves were confirmed with coefficients of determination (R²) ≥ 0.99 at a calibration range of 0.001-0.05 mg/kg. The limits of detection and quantification were 0.003 and 0.01 mg/kg, respectively. Mean average recoveries were 71.5-109.8% and precision was less than 10% for all five samples. In addition, inter-laboratory validation testing revealed that average recovery was 75.4-107.0% and the coefficient of variation (CV) was below 19.4%. The method is suitable for MFDS, CODEX, and EU guideline for residue analysis. Thus, this method can be useful for determining the residue in various food matrixes in routine analysis.

• Progress in Medical Physics
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• v.34 no.1
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• pp.1-9
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• 2023

Purpose: Although ionization chambers are widely used to measure beam commissioning data, point-by-point measurements of all the profiles with various field size and depths are time-consuming tasks. As an alternative, we investigated the feasibility of a linear diode array for commissioning a treatment planning system. Methods: The beam data of a Varian TrueBeam^® radiotherapy system at 6 and 10 MV with/without a flattening filter were measured for commissioning of an Eclipse Analytical Anisotropic Algorithm (AAA) ver.15.6. All of the necessary beam data were measured using an IBA CC13 ionization chamber and validated against Varian "Golden Beam" data. After validation, the measured CC13 profiles were used for commissioning the Eclipse AAA (AAA_CC13). In addition, an IBA LDA-99SC linear diode array detector was used to measure all of the beam profiles and for commissioning a separate model (AAA_LDA99). Finally, the AAA_CC13 and AAA_LDA99 dose calculations for each of the 10 clinical plans were compared. Results: The agreement of the CC13 profiles with the Varian Golden Beam data was confirmed within 1% except in the penumbral region, where ≤2% of a discrepancy related to machine-specific jaw calibration was observed. Since the volume was larger for the CC13 chamber than for the LDA-99SC chamber, the penumbra widths were larger in the CC13 profiles, resulting in ≤5% differences. However, after beam modeling, the penumbral widths agreed within 0.1 mm. Finally the AAA_LDA99 and AAA_CC13 dose distributions agreed within 1% for all voxels inside the body for the 10 clinical plans. Conclusions: In conclusion, the LDA-99SC diode array detector was found to be accurate and efficient for measuring photon beam profiles to commission treatment planning systems.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.26 no.5B
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• pp.447-457
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• 2006

This paper presents a numerical model for the simulations of 2D depth-averaged flows. The shallow water equations are solved numerically by the Characteristic Dissipative Galerkin (CDG) finite element method. For validation, the developed model is applied to the hydraulic jump. The computed results are compared with the analytical solution, revealing good agreement. In addition, flow in a contracting channel showing standing waves is simulated. The calculated water surface profile appears to be qualitatively consistent with the observed data. The foregoing results indicate that the model is capable of simulating the abrupt change in flow field. Next, the model is applied to the flow in a $180^{\circ}$ curved channel. The simulated results show that the velocity near the inner bank is faster than that near the outer bank and the water depth near the inner bank is shallower than that near the outer bank. However, the simulated results show that the velocity distribution across the channel is almost uniform in the bend except the reach close to the end of the bend. This is due to the limitation of the governing equations in which the transverse convection of momentum by the secondary flows along a channel bend is not taken into account.

• Journal of Food Hygiene and Safety
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• v.38 no.3
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• pp.184-191
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• 2023

Nuts are essential components of a healthy diet as they provide nutritional value and bioactive components. Melatonin, is a hormone secreted from the pineal gland of the brain that prevents oxidative damage in various tissues, and also found in plants. This study presents a validation method for extracting and quantitatively analyzing melatonin in nuts, seeds, and beans in Gyeonggi-do; the method utilized chromatographic techniques and optimized extraction procedures, considering the high oil content of nuts. The average content of melatonin in nuts, seeds, and beans was 1200.83 (409.76-2223.56), 934.83 (454.10-1736.60), and 616.46 (494.70-825.12) pg/g, respectively. Melatonin content was higher in the kernel with pellicle than that in the kernel alone in walnuts and chestnuts. Furthermore, the presence of melatonin was lower in newly harvested walnuts, chestnuts, and peanuts than in those stored after being harvested the previous year.