• 한국경영과학회:학술대회논문집
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• 한국경영과학회 1998년도 추계학술대회 논문집
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• pp.223-223
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• 1998

• International Journal of Precision Engineering and Manufacturing
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• 제1권2호
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• pp.35-42
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• 2000

To save time and cost in assembly process and to improve th quality of products, it is very important to choose and optimal assembly sequence. In this paper, we propose a methodology that generates an optimal assembly sequence by using various methods and the knowledge of experts. To illustrate the effectiveness of the proposed methodology, a knowledge-based system is developed, The built system is applied to the case of UBR(Unit Bath Room). The applying result showed the applicability of the developed system.

• 한국정밀공학회지
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• 제20권9호
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• pp.188-196
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• 2003

In order to increase competitiveness and to gain economic benefit, companies ask more and more how to recycle their products in a efficient way. So far, to answer this question, companies are not sufficiently supported by suitable methods specially in the area of disassembly process planning. For this reason, we develop in collaboration with an industrial partner a new method for generating an optimal disassembly sequence. In the presented paper this method will be described in detail by considering the exiting assembly information, disassembly method and disassembly depth. PLM (Profit-Loss Margin) curve that is used to determine disassembly depth consists of profit value, disassembly cost and disassembly effect. Using assessment parameters, generated alternative disassembly sequences are evaluated and optimal disassembly sequence is proposed. This method is applied to generate the optimal disassembly sequence of Door Trim as an example.

• 한국정밀공학회지
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• 제16권5호통권98호
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• pp.29-39
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• 1999

Many industrial products can be assembled in various sequences of assembly operations. To save time and cost in assembly process and to increase the quality of products, it is very important to choose an optimal assembly sequence. In this paper, we propose a methodology that generates an optimal assembly sequence by using the knowledge of experts. First, a product is divided into several sub-assemblies. Next, the disassembly sequences of sub-assembly are generated using disassembly rules and special information can be extracted through the disassembly process. By combining every assembly sequence of sub-assemblies, we can generate all the possible assembly sequences of a product. Finally, the expert system evaluates all the possible assembly sequences and finds an optimal assembly sequence. It can be achieved under consideration of the parameters such as assembly operation, tool change, safety of part. basepart location, setup change, distance, and orientation. The developed system is applied to UBR(Unit Bath Room) example.

• International Journal of Precision Engineering and Manufacturing
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• 제6권1호
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• pp.42-50
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• 2005

In order to increase competitiveness and to gain economic benefit, companies ask more and more how to recycle their products in an efficient way. So far, to answer this question, companies are not sufficiently supported by suitable methods specially in the area of disassembly process planning. For this reason, we develop in collaboration with an industrial partner a new method for generating an optimal disassembly sequence. In this paper this method will be described in detail by considering the exiting assembly information, disassembly method and disassembly depth. PLM(Profit-Loss Margin) curve that is used to determine disassembly depth consists of profit value, disassembly cost and disassembly effect. Using assessment parameters, generated alternative disassembly sequences are evaluated and an optimal disassembly sequence is proposed. This method is applied to generate the optimal disassembly sequence of Door Trim as an example.

• Tuberculosis and Respiratory Diseases
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• 제79권2호
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• pp.85-90
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• 2016

Background: Lung cancer is the most common cause of cancer related death. Alterations in gene sequence, structure, and expression have an important role in the pathogenesis of lung cancer. Fusion genes and alternative splicing of cancer-related genes have the potential to be oncogenic. In the current study, we performed RNA-sequencing (RNA-seq) to investigate potential fusion genes and alternative splicing in non-small cell lung cancer. Methods: RNA was isolated from lung tissues obtained from 86 subjects with lung cancer. The RNA samples from lung cancer and normal tissues were processed with RNA-seq using the HiSeq 2000 system. Fusion genes were evaluated using Defuse and ChimeraScan. Candidate fusion transcripts were validated by Sanger sequencing. Alternative splicing was analyzed using multivariate analysis of transcript sequencing and validated using quantitative real time polymerase chain reaction. Results: RNA-seq data identified oncogenic fusion genes EML4-ALK and SLC34A2-ROS1 in three of 86 normal-cancer paired samples. Nine distinct fusion transcripts were selected using DeFuse and ChimeraScan; of which, four fusion transcripts were validated by Sanger sequencing. In 33 squamous cell carcinoma, 29 tumor specific skipped exon events and six mutually exclusive exon events were identified. ITGB4 and PYCR1 were top genes that showed significant tumor specific splice variants. Conclusion: In conclusion, RNA-seq data identified novel potential fusion transcripts and splice variants. Further evaluation of their functional significance in the pathogenesis of lung cancer is required.

• Journal of Communications and Networks
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• 제11권3호
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• pp.240-247
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• 2009

The results of performance analysis by adopting the channel scenarios characterized as Weibull fading for an multicarrierdirect sequence-coded division multiple access (MC-DS-CDMA) system are proposed in this investigation. On the other hand, an approximate simple expression with the criterion of bit error rate (BER) versus signal-to-noise ratio (SNR) method is derived for an MC-DS-CDMA system combining with maximal ratio combining (MRC) diversity based on the moment generating function (MGF) formula of Weibull statistics, and it associates with an alternative expression of Gaussian Q-function. Besides, the other point of view on the BER performance evaluation of an MC-DS-CDMA system is not only the assumption of both single-user and multi-user cases applied, but the phenomena of partial band interference (PBI) is also included. Moreover, in order to validate the accuracy in the derived formulas, some of the system parameters, such as Weibull fading parameter (${\beta}$), user number (K), spreading chip number (N), branch number (L), and the PBI (JSR) values, etc., are compared with each other in the numerical results. To the best of author's knowledge, it is a brand new idea which proposes the evaluation of the system performance for an MC-DS-CDMA system over the point of view with Weibull fading channel.

• 한국정밀공학회지
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• 제23권11호
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• pp.68-77
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• 2006

Nowadays, the increasing global competition forces automobile manufacturer to increase quality and to reduce the cost and time for manufacturing planning. To solve these problems, automobile manufacturers try to apply digital manufacturing technologies. In this paper, a concept of method for planning the digital assembly system is proposed. Based on the requirements of assembly tasks obtained through product analysis, the function and sequence modeling for assembly process is executed using the IDEF0 and UML model. For implementation of digital assembly system, the selected components are modeled by using 3D CAD tools. According to the system configuration strategy, lots of the alternative solutions for the assembly system are generated. Finally, the optimal assembly system is chosen by the evaluation of the alternative solutions with TOPSIS(Technique for Order Preference by Similarity to Ideal Solution) method. According to proposed procedure, digital laser welding system is implemented in DELMIA.

• Geomechanics and Engineering
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• 제21권5호
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• pp.413-422
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• 2020

The choice of eco-friendly materials for ground improvement is a necessary way forward for sustainable development. Adapting naturally available biopolymers will render the process of soil stabilization carbon neutral. An attempt has been made to use β-glucan, a natural biopolymer for the stabilization of lean clay as a sustainable alternative with specific emphasis on comprehending the effect of confining stresses on lean clay through triaxial compression tests. A sequence of laboratory experiments was performed to examine the various physical and mechanical characteristics of β-glucan treated soil (BGTS). Micro-analysis through micrographs were used to understand the strengthening mechanism. Results of the study show that the deviatoric stress of 2% BGTS is 12 times higher than untreated soil (UTS). The micrographs from Scanning Electron Microscopy (SEM) and the results of the Nitrogen-based Brunauer Emmett Teller (N₂-BET) analysis confirm the formation of new cementitious fibres and hydrogels within the soil matrix that tends to weld soil particles and reduce the pore spaces leading to an increase in strength. Hydraulic conductivity (HC) and compressibility reduced significantly with the biopolymer content and curing period. Results emphases that β-glucan is an efficient and sustainable alternative to the traditional stabilizers like cement, lime or bitumen.

• 산업공학
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• 제19권3호
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• pp.236-244
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• 2006

Postal code is essential for improving efficiency of mail sorting. The Korean postal code, which is introduced in 1970 and had been reformed two times, has controversial issues because of changed postal environments such as modification of administrative districts and logistical transformation into a hub-and-spokes structure. In this study, we propose several improvement and evaluation methods in order to prepare an alternative plan of postal code system. After performing status analysis, we define the customers of postal code and analyze the requirements of them. The 6 proposed new postal code systems are based on each customer groups’ requirements. To evaluate the new systems, we develop several quantitative and qualitative indexes and make a survey of postal experts. Besides, we evaluate the influence of them to the postal environments including delivery sequence sorting process.