• Biotechnology and Bioprocess Engineering:BBE
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• v.5 no.6
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• pp.387-394
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• 2000

The relationship between Man and yeast has been a successful and enduring one. The characteristics of yeast have made it an ideal tool in scientific research and as such, it has been used extensively. In this review some of the advantages, methods and applications of yeasts in the biosensor field are outlined. In doing so, we propose a eukaryotic alternative to the current battery of bacteria-based microbial biosensors.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.35 no.4
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• pp.435-447
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• 1999

It is main objective of this approach to present a method to analyse stochastic design sensitivity for problems of structural dynamics with randomness in design parameters. A combination of the adjoint variable approach and the second order perturbation method is used in the finite element approach. An alternative form of the constant functional that holds for all times is introduced to consider the time response of dynamic sensitivity. The terminal problem of the adjoint system is solved using equivalent homogeneous equations excited by initial velocities. The numerical procedures are shown to be much more efficient when based on the fold superposition method: the generalized co-ordinates are normalized and the correlated random variables are transformed to uncorrelated variables, whereas the secularities are eliminated by the fast Fourier transform of complex valued sequences. Numerical algorithms have been worked out and proved to be accurate and efficient : they can be readily adapted to fit into the existing finite element codes whose element derivative matrices can be explicitly generated. The numerical results of two cases -2 dimensional portal frame for the comparison with reference and 3-dimensional frame structure - for the deterministic sensitivity analysis are presented.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.12
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• pp.7761-7762
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• 2013

Alternative strategies such as visual inspection of cervix with acetic acid, are real time, economical and easily implemented methods for cervical cancer screening. However, variable sensitivity and specificity have been observed in various community based studies. The possible reasons could include variation in man power training, light source used for visualization, and preparation of diluted (4-5%) acetic acid and its storage. A standardized protocol for training, teaching material (easy to understand in the local language) for trainees, supervision and reinforcement by intermittent and supplementary training to check the quality of their observation, a standard protocol for preparation dilute acetic acid and its storage and a standard good light source (equivalent to day light) are needed to minimize the variation in sensitivity and specificity of VIA in community settings.

• KIEAE Journal
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• v.16 no.2
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• pp.17-22
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• 2016

Purpose: Sensitivity analysis offers a good guideline for designing energy conscious buildings, which is fitted to a specific building configuration. Sensitivity analysis is, however, still too expensive to be a part of regular design process. The One-at-a-time (OAT) is the most common and simplest sensitivity analysis method. This study aims to propose a reasonable ground that the OAT can be an alternative method for the variance-based method in some early design scenarios, while the variance-based method is known adequate for dealing with nonlinear response and the effect of interactions between input variables, which are most cases in building energy simulations. Method: A test model representing the early design phase is built in the DOE2 energy simulations. Then sensitivity ranks between the OAT and the Variance-based methods are compared at three U.S. sites. Result: Parameters in the upper rank by the OAT do not much differ from those by the Main effect index. Considering design practices that designers would chose the most energy saving design option first, this rank similarity between two methods seems to be acceptable in the early design phase.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.37 no.3
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• pp.611-619
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• 2017

This paper intends to develop unit water production cost (UWPC) between alternative water resources including desalination, freshwater reservoirs, single-purpose dams, underground dams, and two indirect water in-take technologies - riverbank filtration and aquifer storage and recovery (ASR). The UWPCs of water supply schemes including each alternative are determined based on project cost, and operation and maintenance estimation models, which were developed based on real project cost data. The sensitivity analysis of UWPCs reveals that ASR is the lowest cost option in producing drinkable water among the alternatives, followed by riverbank filtration and underground dam. It is expected that economics related to the finding plays a critical role in supporting water resources planning and budget allocation for central and local water authority in Korea.

• Steel and Composite Structures
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• v.23 no.6
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• pp.683-690
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• 2017

In the stability and sensitivity design and diagnosis approaches, there are various methodologies available. Bond graph modeling by lumping technique is one of the universal methodologies in methodical analysis used by many researchers in all over the world. The accuracy of the method is validated in different arenas. Bond graphs are a concise, pictorial representation of the energy storage, dissipation and exchange mechanisms of interacting dynamic systems, subsystems and components. This paper proposes a bond graph modeling for distributed parameter systems using lumping techniques. Therefore, a steel frame structure was modeled to analyze employing bond graph modeling of distributed system using lumping technique. In the analytical part, the effectiveness of bond graphs to model this system is demonstrated. The dynamic responses of the system were computed and compared with those computed from the finite element analysis. The calculated maximum deflection time histories were found to be comparable. The sensitivity and the stability of the steel frame structure was also studied in different aspects. Thus, the proposed methodology, with its simplicity, can be used for stability and sensitivity analyses as alternative to finite element method for steel structures. The major value brought in the practical design is the simplicity of the proposed method for steel structures.

• Food Science and Biotechnology
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• v.17 no.5
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• pp.1052-1059
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• 2008

Sequential Sensitivity Analysis (SSA) and conditional stimulus model have been developed to describe sequence effects in difference tests and proposed to generate prediction of differences in sensitivity between various test protocols and to assist the appropriate selection of difference test. Yet, such models did not furnish a complete explanation of the relative sensitivity in 4 different versions of 3-alternative forced choice (AFC) tests where various interstimulus rinses were introduced. In the present study, the vector of the contrasts between various conditional stimuli were measured using same-different and 2-AFC and a new 16-distribution conditional stimulus model was developed by refining Lee and O'Mahony's contrast model. This new model gave superior predictions than previous models.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2001.04a
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• pp.354-357
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• 2001

The developed method is proposed to identify rotor dynamic parameters. The method known imbalance vector, which renders over-determined linear system equation. The solution of the system equation can be obtained using least square method. The sensitivity analysis is performed to extract optimized solution, which is considered to be insensitive to inherent measurement errors. As an alternative approach to identify the parameters of bearings and rotor, adding a known imbalance to the rotor produces another equation set to make the system equations over-determined and linearly independent.

• KSTLE International Journal
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• v.1 no.1
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• pp.29-33
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• 2000

In this study, a methodology is developed and confirmed to find the physical contact between the slider and disc due to the defects of disk during head seeking operation using acoustic emission (AE) signal. The head/disk contact was detected during random and standard seeks, whereas no contact was detected during track fellowing. During standard and random seeks, the torsion mode of slider excitation was observed at 680KHz. Therefore, it is thought that AE technique can be used as an alternative method of the glide test by monitoring existence of the torsional mode of the slider during seek operation or can be used to detect the spacing loss during seeking operation. By appropriately choosing the location of the sensor an order of magnitude increase in the sensitivity for RMS AE signal is observed. Therefore we can find take-off velocity clearly with high signal to noise ratio of AE signal.

• Transactions of the Korean Society of Pressure Vessels and Piping
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• v.17 no.2
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• pp.126-136
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• 2021

During operation of nuclear power plants, the fatigue assessment should be conducted repeatedly, considering changes of operating environments. For the case that cumulative usage factors (CUFs) may exceed the acceptance limit, flaw tolerance evaluation can be an alternative method to meet the regulatory requirements. In this respect, this paper analyzes the effects of the input variables for flaw tolerance evaluation based on ASME BPVC Section XI Appendix L. The reference analysis is performed for the example problem in NUREG/CR-6934. Then effects of the crack orientation, stress intensity factor solutions, thermal stress profiles, fatigue stress decomposition and fatigue crack growth curves are considered for the sensitivity analysis. The results show that the stress analysis considering the actual environment plays a crucial role in flaw tolerance evaluation.