• Journal of the Korean earth science society
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• v.27 no.4
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• pp.374-389
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• 2006

The purpose of this study was to investigate the alternative models of seasonal changes that preservice secondary teachers presented using the Lakatosian methodology. Participants included 74 undergraduate students who majored in science education within the college of education. Their responses to these questions revealed students' alternative models were inconsistent with scientific models. A great deal of this apparent inconsistency could be explained by assuming that the students used, in a consistent fashion, a alternative core belief on seasonal changes. This study also discussed the core beliefs and the possible sources held by preservice teachers in order to overcome their alternative models. The sources of alternative models may lie in the contents used in textbooks.

• BMB Reports
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• v.57 no.8
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• pp.352-362
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• 2024

Hematopoietic stem cell transplantation (HSCT) remains an indispensable therapeutic strategy for various hematological diseases. This review discusses the pivotal role of bone marrow (BM) niches in influencing the efficacy of HSCT and evaluates the current animal models, emphasizing their limitations and the need for alternative models. Traditional animal models, mainly murine xenograft, have provided significant insights, but due to species-specific differences, are often constrained from accurately mimicking human physiological responses. These limitations highlight the importance of developing alternative models that can more realistically replicate human hematopoiesis. Emerging models that include BM organoids and BM-on-a-chip microfluidic systems promise enhanced understanding of HSCT dynamics. These models aim to provide more accurate simulations of the human BM microenvironment, potentially leading to improved preclinical assessments and therapeutic outcomes. This review highlights the complexities of the BM niche, discusses the limitations of current models, and suggests directions for future research using advanced model systems.

• Health Policy and Management
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• v.2 no.1
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• pp.80-114
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• 1992

Current compensation schemes for medical malpractice based on negligence is absolutely malfunctioning in Korea. Focussing on the reform of present tort systems for resolving medical malpractice disputes, this paper discusses the alternative models of the Social Relief Schemes for Medical Malpractice (SRSMM). Alternative models of SRSMM should fundamentally be based on either negligence or nofalult compensation principle. On the foundation of the previous relief principle, the SRSMM should be equupped with three major components-the preventio/reduction of the sharp increasing medical malpractice, the effective and efficient resolving process for malpractice disputes and the proper social financing scheme for compensation. The paper deals with pros and cons of the possible alternative models for reform centering on the three major components of the scheme. As conclusions, administrative arbitration machinaries and a compulsory fund for compensating the injured under the negligence principle are proposed to resolve the current problems Korea has faced.

• Journal of applied mathematics & informatics
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• v.6 no.2
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• pp.599-609
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• 1999

Neural networks are explored as an alternative to a regres-sion model for prediction of the number of daily household vehicular trips. This study focuses on contrasting a neural network model with a regression model in term of variable selection as well as the appli-cation of these models for prediction of extreme observations, The differences in the models regarding data transformation variable selec-tion and multicollinearity are considered. The results indicate that the neural network model is a viable alternative to the regression model for addressing both messy data problems and limitation in variable structure specification.

• Journal of The Korean Association For Science Education
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• v.25 no.6
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• pp.698-709
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• 2005

When modeling students' conceptual understanding, there are several different frameworks, among which are the alternative conception framework and the mental model framework, which converge to suggest a form of knowledge representation. However, little research has explained how they are different from each other and from memory. The purpose of this study was to develop a new mental model theory that integrates the different terminologies and their background theories, which refer to students' ideas not only in science education, but also in other research areas. For this purpose, at first, we compared different terminologies including alternative conception, p-prim, and mental models, and the underlying theories used for representing students' ideas in learning science. Through such comparison, we tried to find the relationship among them. We reviewed related literature and synthesized the results from both cognitive science (related research areas) and science education approaches, especially, Vosniadou's mental model theory. Based on reviewing previous studies, we have developed a preliminary mental model theory 'an integrated theoretical structure of mental models'. We applied the new mental model theory to interpret data on students' ideas about circular motion from our previous research. We expect our new mental model theory will help us understand how students form their own ideas in science from an integrated perspective.

• Proceedings of the Korea Water Resources Association Conference
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• 1992.07a
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• pp.443-447
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• 1992

This study describes the strategy for advanced decision support system (ADSS) development for integrated management of water resources and quality in reservoir systems. The developed ADSS consists of database that contain hydrologic data, observed operational data, and data to support specific reservoir operations simulation, optimization models, and water quality models. The optimization model, mass balance simulation model and water quality models are used in a general prototype ADSS, menu driven controlling framework that assists the user to specify and evaluate the alternative operational scenarios at one time. These alternative scenarios are evaluated by the models and the results are compared through the use of a graphical based display system. This graphical based system uses an icon based schematic representation of the system to organize the presentation of the results. The ADSS includes the ability to use monthly or weekly time periods of analysis for the models and it can use monthly historical or stochastically generated inflows.

• Earthquakes and Structures
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• v.14 no.6
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• pp.551-565
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• 2018

Experimental testing is considered the most realistic approach to obtain a detailed representation of the nonlinear behaviour of masonry-infilled reinforced concrete (RC) structures. Among other applications, these tests can be used to calibrate the properties of numerical models such as simplified macro-models (e.g., strut-type models) representing the masonry infill behaviour. Since the significant cost of experimental tests limits their widespread use, alternative approaches need to be established to obtain adequate data to validate the referred simplified models. The proposed paper introduces a detailed finite element modelling strategy that can be used as an alternative to experimental tests to represent the behaviour of masonry-infilled RC frames under earthquake loading. Several examples of RC infilled frames with different infill configurations and properties subjected to cyclic loading are analysed using the proposed modelling approach. The comparison between numerical and experimental results shows that the numerical models capture the overall nonlinear behaviour of the physical specimens with adequate accuracy, predicting their monotonic stiffness, strength and several failure mechanisms.

• Journal of the Korean earth science society
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• v.28 no.6
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• pp.645-654
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• 2007

The purpose of this study was to investigate students' mental models and alternative conceptions about the Earth's interior. A total of 126 10th grade students participated in this study. They were requested to draw Earth's interior tasks and were interviewed about their mental models. A coding frame was designed to classify the students' drawings and interview responses, and then a four step cognitive model was established based on the frame of coding. In addition, the relationship of mental models was compared in terms of students' gender, and the type of alternative conceptions was analysed. The research results showed a variety of alternative conceptions on the interior of the Earth. The classified mental models showed naive mental model (11%), unstable mental model (81%), conceptual model (8%), while 69% of all sampled students accounted for the static process. The gender difference in the cognitive model showed no statistical significance.

• Nuclear Engineering and Technology
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• v.31 no.5
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• pp.465-475
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• 1999

The objective of the present work is to assess the analysis capability of two wall film condensation models, the default and the alternative models, of RELAP5/MOD3.2 on condensation experiments in the presence of noncondensable gas in a vertical tube of PCCS of CP-1300. In the calculation of a base case the default model of RELAP5/MOD3.2 under-predicts the heat transfer coefficients, and Its alternative model over-predicts them throughout the condensing tube, Also, both models over-predict the void fractions. The nodalization study shows that the variation of the node number does not change both modeling results of RELAP5/MOD3.2 Sensitivity study for varying input parameters shows that the inlet steam-air mixture flow rate, the inlet air mass fraction, and the inlet saturated steam temperature give significant changes of their heat transfer coefficients Run statistics show that the grind time of the default model is always higher than that of the alternative model by about 23%.

• Toxicological Research
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• v.21 no.1
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• pp.1-14
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• 2005

Transgenic mouse models have been introduced and accepted by regulatory bodies as an alternative to carcinogenicity assay models to predict and evaluate chemical carcinogens. The recent research outcomes in transgenic mouse models have made progressive advances in the understanding of chemical carcinogenesis and the evaluation of potential human carcinogens. However, these models still remain to be insufficient assay systems although the insufficiencies have been recognised and are being resolved. Based on up to date information from literature, this review article intends to understand currently accepted transgenic mouse models, issues arising from study design, interpretation of the study, results of validation project and their cancer prediction rate, and further perspectives of cancer assay models from the regulatory view point.