• Title/Summary/Keyword: alignments

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Development of Model for Highway Design Consistency Evaluation (2차로 도로선형 설계일관성 평가기준 개발)

  • Lee, Su-Il;Lee, Su-Beom;Kim, Jeong-Hyeon;Kim, Jang-Uk
    • Proceedings of the KOR-KST Conference
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    • 2007.02a
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    • pp.306-314
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    • 2007
  • This paper is to develop a model for evaluation of highway alignment design considering the driver's behavior in order to enhance the highway safety. Under the conditions, this research included a new evaluation criteria development and an analysis on how to change evaluation criteria according to roadway alignments, to evaluate safety. The vehicle spacing and speed deviation are suggested as new evaluation index The evaluation criteria model can be used to compare the anticipated safety performance of two or more geometric alternatives for a proposed highway improvement.

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GTVseq: A Web-based Genotyping Tool for Viral Sequences

  • Shin, Jae-Min;Park, Ho-Eun;Ahn, Yong-Ju;Cho, Doo-Ho;Kim, Ji-Han;Kee, Mee-Kyung;Kim, Sung-Soon;Lee, Joo-Shil;Kim, Sang-Soo
    • Genomics & Informatics
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    • v.6 no.1
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    • pp.54-58
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    • 2008
  • Genotyping Tool for Viral SEQuences (GTVseq) provides scientists with the genotype information on the viral genome sequences including HIV-1, HIV-2, HBV, HCV, HTLV-1, HTLV-2, poliovirus, enterovirus, flavivirus, Hantavirus, and rotavirus. GTVseq produces alternative and additive genotype information for the query viral sequences based on two different, but related, scoring methods. The genotype information produced is reported in a graphical manner for the reference genotype matches and each graphical output is linked to the detailed sequence alignments between the query and the matched reference sequences. GTVseq also reports the potential 'repeats' and/or 'recombination' sequence region in a separated window. GTVseq does not replace completely other well-known genotyping tools such as NCBI's virus sequence genotyping tool (http://www.ncbi. nlm.nih.gov/projects/genotyping/formpage.cgi), but provides additional information useful in the confirmation or for further investigation of the genotype(s) for the newly isolated viral sequences.

Intrinsic bent DNA colocalizes with the sequence involved in the Nd-sD mutation in the Bombyx mori fibroin light chain gene

  • Barbosa, Joice Felipes;Bravo, Juliana Pereira;Takeda, Karen Izumi;Zanatta, Daniela Bertolini;Silva, Jose Luis Da Conceicao;Balani, Valerio Americo;Fiorini, Adriana;Fernandez, Maria Aparecida
    • BMB Reports
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    • v.41 no.5
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    • pp.394-399
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    • 2008
  • Multiple sequence alignments of the Bombyx mori fibroin light chain gene (fib-L) from hybrids and from Chinese and Japanese strains demonstrated that 51.6% of the fib-L third intron is conserved. One of these conserved segments, 41 bp long, contains the sequence CGTTATTATACATATT, which is duplicated in the B. mori Nd-$s^D$ mutant. In the present work, electrophoretic mobility assays and computational analyses revealed a major peak of intrinsic bent DNA within the segment that undergoes breakage in the previously-described Nd-$s^D$ mutation. This result suggested that this intrinsically-curved region might mediate DNA cleavage and enhance recombination events in the third intron of the Bombyx mori fib-L gene.

A Genomics Tool for Microbial Genome Comparison Using BLAST/FASTA (BLAST/FASTA를 활용한 미생물 유전체 비교용 도구의 개발)

  • Tae, Hongseok;Lee, Daesang;Park, Wan;Park, Kiejung
    • Korean Journal of Microbiology
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    • v.38 no.4
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    • pp.267-275
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    • 2002
  • We have developed GComp as an analysis tool for microbial genome comparison. This tool exploits BLAST or FASTA as a preprocessing program for local alignments to detect homologous regions, parses the homology search results, and generates tables and files to show homology relationship between two genomes at a glance. The interface for graphical representation of the comparative genomic analysis has been also implemented. Our test cases shows that the program can be useful in practice for intuitive and quantitative comparison of microbial genome sequence pairs as well as self-genome analysis. A few additional features have been devised and designed, which will be added in the further development.

Subway Line 9 Express Transit Service & Direct Link Proposal with Line 5 (뉴스초점 - 지하철 9호선의 급행화 및 5호선과의 직결대안)

  • Lee, Sun
    • Journal of the Korean Professional Engineers Association
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    • v.42 no.3
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    • pp.41-46
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    • 2009
  • A new subway, line 9 linking Western and Eastern Seoul began its services for citizens between Gimpo airport and Gangnam area within 30 minutes by express transit service. Seoul Metro Line 9 Corporation plans to operate both local transit service which will stop at every station, and express transit service that will stop at several key stations including junctions. The passengers on line 9 will be able to transfer to lines 2, 3, 5, 8, Bundang and Incheon International Airport. The Line 9 is expected to disperse the demand for line 2, having the most number of subway users, and will provide passengers with less crowded travel. The new line will also help residents in southern Seoul outskirts and Gyeonggi provincial cities including Bundang vicinity, and Gangdong area commuters get better access to Gimpo and incheon Airports. The Corporation expects to transfer 560,000 passengers daily by the subway line 9. Seoul Development Institute conducted network reshuffle study for Seoul Metro system to sort out congestion problem due to its irrational line alignments and inconvenient transfer. Among several candidate plans of network reshuffling, the direct connection of line 9 with line 5 was chosen as a pilot study. The study found that direct connection of the 2 lines is essential for enhancing transit utility and reducing automobile commuters.

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Effect of Pelvic Tilting and the Back-belt on Electromyographic Activity of Erector Spinae During Lifting (골반경사 방향과 허리벨트 착용이 물건 들고 일어서기 시 척추기립근의 활동전위에 미치는 영향)

  • Park, Hyung-Ki;Kim, Tack-Hoon
    • The Journal of the Korea Contents Association
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    • v.9 no.3
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    • pp.296-304
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    • 2009
  • The purpose of this study were to examine the effect of two different pelvic alignments and the back belt on electromyographic(EMG) activity of the erector spinae during lifting. The results were as follows: 1) EMG activity of erector spinae was greater when the pelvis was tilted anteriorly than when the pelvis was tilted posteriorly during lifting. 2) EMG activity of erector spinae was greater when the back belt than when without the back belt during lifting. These results suggest that the greater EMG activity of erector spinae with an anterior pelvic tilt position and with back belt during lifting may ensure optimal muscular support for the spine while handling loads.

A study on precision drive mechanism for monochromator grating (단색 분광기 회절격자의 정밀 구동 기구에 관한 연구)

  • Kim, D.S.;Park, K.B.;Kwak, Y.K.
    • Journal of the Korean Society for Precision Engineering
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    • v.14 no.11
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    • pp.42-49
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    • 1997
  • The extent of absorption and transmitance of the light that passes through some material is changed as the wavelength of the light varies, and which makdes it possible to estimate characteristics of the material. Spectrometer is a measurement system that can analyze the characteristics of material by using this principle. Its application field is so wide that it can be applied to all the arease that are concerned with analyzing materials : biological, environmental, medical and chemical area etc. This study is focused on developing precision sine drive mechanism for grating monochromator which is the most important part of the spectrometers. It is designed to be simple in struicture. It is achieved to derive basic principles to manipu- late precision sine drive mechanism : it should be aligned with a condition that .beta. , the angle between grat- ing normal and grating rod should be the same as .gamma. , the one between moving nut's normal and sliding guide. And also, it's found that the mis-alignments of the grating and mirrors are not the main factor in guaranteeing the linearity of sine drive mechanism. Performance evaluation is achieved by a standard sample by comparing experimental results with standard values. It results in wavelength accuracy of .+-. 0.5nm and resolution of 1nm. Conclusively, it can be verified that the sine drive mechanism developed in this study is not only simple in structure, but also stable and excellent in performanes.

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A Study on the Application of Extension Method in Railway Transition Curved Zone Considering Field Status (지형여건을 고려한 철도 완화곡선 연장방법의 적용성에 관한 연구)

  • Jeong Eui Hwan
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.22 no.4
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    • pp.391-400
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    • 2004
  • Railway curved zone have crucial effects on the speed of train. Length of transition curve is one of the important factor for alignment compatibility estimation in this sections, this value is decided by running speed and Cant. In this study, the extension method of transition curve is evaluated, based on the alignment of Jang Hang-Line, investigated field conditions of the sections in the curves exist. This research result show that changing of transition curve was proved by necessary to approximately two thirds of the curved sections, and method of fixing central point of track centerline and changing radius of curvature minimize the maximum shift in track centerline and deviation of radius, and also may be effective method for alignment suitability and speed up in case overall improvement is difficult.

Multiple Sequence Aligmnent Genetic Algorithm (진화 알고리즘을 사용한 복수 염기서열 정렬)

  • Kim, Jin;Song, Min-Dong;Choi, Hong-Sik;Chang, Yeon-Ah
    • Korean Journal of Microbiology
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    • v.35 no.2
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    • pp.115-120
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    • 1999
  • Multiple Sequence Alignment of DNA and protem sequences is a imnport'mt tool in the study of molecular evolution, gene regulation. and prolein suucture-function relationships. Progressive pairwise alignment method generates multiple sequence alignment fast but not necessarily with optimal costs. Dynamic programming generates multiple sequence alig~~menl with optimal costs in most cases but long execution time. In this paper. we suggest genetlc algorithm lo improve the multiple sequence alignment generated from the cnlent methods, describe the design of the genetic algorithm, and compare the multiple sequence alignments from 0111 method and current methods.

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Plagiarism Detection among Source Codes using Adaptive Methods

  • Lee, Yun-Jung;Lim, Jin-Su;Ji, Jeong-Hoon;Cho, Hwaun-Gue;Woo, Gyun
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.6 no.6
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    • pp.1627-1648
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    • 2012
  • We propose an adaptive method for detecting plagiarized pairs from a large set of source code. This method is adaptive in that it uses an adaptive algorithm and it provides an adaptive threshold for determining plagiarism. Conventional algorithms are based on greedy string tiling or on local alignments of two code strings. However, most of them are not adaptive; they do not consider the characteristics of the program set, thereby causing a problem for a program set in which all the programs are inherently similar. We propose adaptive local alignment-a variant of local alignment that uses an adaptive similarity matrix. Each entry of this matrix is the logarithm of the probabilities of the keywords based on their frequency in a given program set. We also propose an adaptive threshold based on the local outlier factor (LOF), which represents the likelihood of an entity being an outlier. Experimental results indicate that our method is more sensitive than JPlag, which uses greedy string tiling for detecting plagiarism-suspected code pairs. Further, the adaptive threshold based on the LOF is shown to be effective, and the detection performance shows high sensitivity with negligible loss of specificity, compared with that using a fixed threshold.