• 한국재료학회지
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• 제25권10호
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• pp.552-558
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• 2015

The mechanical properties and microstructures of Aluminum 6056 alloys were investigated for their use in the fabrication of a piton block. The EN-AW6056 alloys exhibited a tensile strength of 375 MPa for a solution treatment temperature of $550^{\circ}C$ for 2 h followed by an aging treatment at $190^{\circ}C$ for 4 h. The microstructures of the heat treated specimen showed that the $Mg_2Si$ phase with a size of 3~5 um was dispersed throughout the aluminum matrix when the heat treatment was done. Moreover, in order to identify the forgeability of the specimen, upsetting tests were done. For up to 80 % of the upsetting ratio, the specimen maintained its original shape, and at above 80 % of the upsetting ratio, the specimen underwent crack development. The specimen was successfully forged without any defects with the examined material conditions. The material conditions together with the forging conditions are discussed in terms of the microstructures and mechanical properties.

• 치위생과학회지
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• 제20권4호
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• pp.213-220
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• 2020

Background: The leaves of Perilla frutescens, commonly called perilla and used for food in Korea, contain components with a variety of biological effects and potential therapeutic applications. The purpose of this study was to identify the components of 70% ethanol extracted Perilla frutescens (EEPF) and determine its inhibitory effects on oral microbial activity and production of nitric oxide (NO) and prostaglandin E2 (PGE2) in lipopolysaccharides (LPS)-stimulated Raw264.7 macrophages, consequently, to confirm the possibility of using EEPF as a functional component for improving the oral environment and preventing inflammation. Methods: One kg of P. frutescens leaves was extracted with 70% ethanol and dried at -70℃. EEPF was analyzed using high-performance liquid chromatography analysis, and antimicrobial activity against oral microorganisms was revealed using the disk diffusion test. Cell viability was elucidated using a methylthiazolydiphenyl-tetrazolium bromide assay, and the effect of EEPF on LPS-induced morphological variation was confirmed through microscopic observation. The effect of EEPF on LPS-induced production of pro-inflammatory mediators, NO and PGE2 was confirmed by the NO assay and PGE2 enzyme-linked immunosorbent assay. Results: The main component of EEPF was rosemarinic acid, and EEPF showed weak anti-bacterial and anti-fungal effects against microorganisms living in the oral cavity. EEPF did not show toxicity to Raw264.7 macrophages and had inhibitory effects on the morphological variations and production of pro-inflammatory mediators, NO and PGE2 in LPS-stimulated Raw264.7 macrophages. Conclusion: EEPF can be used as a functional material for improving the oral environment through the control of oral microorganisms and for modulating inflammation by inhibiting the production of inflammatory mediators.

• 한국재료학회지
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• 제30권12호
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• pp.678-686
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• 2020

Microstructural characteristics of directionally solidified René 80 superalloy are investigated with optical microscope and scanning electron microscope; solidification velocity is found to change from 25 to 200 μm/s under the condition of constant thermal gradient (G) and constant alloy composition (Co). Based on differential scanning calorimetry (DSC) measurement, γ phase (1,322 ℃), MC carbide (1,278 ℃), γ/γ' eutectic phase (1,202 ℃), and γ' precipitate (1,136 ℃) are formed sequentially during cooling process. The size of the MC carbide and γ/γ' eutectic phases gradually decrease with increasing solidification velocity, whereas the area fractions of MC carbide and γ/γ' eutectic phase are nearly constant as a function of solidification velocity. It is estimated that the area fractions of MC carbide and γ/γ' eutectic phase are determined not by the solidification velocity but by the alloy composition. Microstructural characteristics of René 80 superalloy after solid solution heat-treatment and primary aging heat-treatment are such that the size and the area fraction of γ' precipitate are nearly constant with solidification velocity and the area fraction of γ/γ' eutectic phase decreases from 1.7 % to 0.955 %, which is also constant regardless of the solidification velocity. However, the size of carbide solely decreases with increasing solidification velocity, which influences the tensile properties at room temperature.

• 한국경제지리학회지
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• 제25권3호
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• pp.320-338
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• 2022

본 연구는 한국의 창업생태계 발달 과정에서 기업가정신이 지역별로 어떻게 차이를 보이는지, 그 이유는 무엇인지 탐구한다. 19인을 대상으로 반구조화된 인터뷰를 진행하여 서울대와 카이스트라는 캠퍼스 창업생태계를 연구대상으로 각 생태계의 형성과정과 구성요소를 비교했다. 첫째, 두 생태계는 1996년을 전후로 창업생태계를 형성해 현재는 다양한 지원조직과 행위자들을 보유한 '제2벤처붐'을 경험하고 있다. 둘째, 두 생태계는 물리적, 사회적, 문화적 속성에서 차이점을 보였다. 특히 네트워크 구조에서 서울대 생태계는 뚜렷한 앵커기관이 존재했으나 카이스트 생태계는 분산되어 있었다. 셋째, 두 생태계의 네트워킹 문화가 차이를 보임은 고유한 지역문화로 인해, 개인이 인식하는 지역의 기업가적 기회에 차이가 있기 때문이었다. 즉, 창업생태계의 유지 및 성장 과정은 본질적으로 문화적이며, 지역마다 차이를 보인다.

• Safety and Health at Work
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• 제11권4호
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• pp.405-417
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• 2020

Background: Electrical socket outlets are used continuously until a failure occurs because they have no indication of manufacturing date or exchange specifications. For this reason, 659 electrical fires related to electrical socket outlets broke out in the Republic of Korea at 2018 only, an increase year on year. To reduce electrical fires from electrical socket outlets, it is necessary to perform an accelerated test and analyze the thermal, insulation resistance, and material properties of electrical socket outlets by installation years. Methods: Thermal characteristics were investigated by measured the temperature increase of electrical socket outlets classified according to year with variation of the current level. Insulation resistance characteristics was measured according to temperature for an electrical socket outlets by their years of use. Finally, to investigate the thermal and insulation resistance characteristics in relation to outlet aging, this study analyzed electrical socket outlets' conductor surface and content, insulator weight, and thermal deformation temperature. Results: Analysis showed, regarding the thermal characteristics, that electrical socket outlet temperature rose when the current value increased. Moreover, the longer the time that had elapsed since an accelerated test and installation, the higher the electrical socket outlet temperature was. With respect to the insulation resistance properties, the accelerated test (30 years) showed that insulation resistance decreased from 110 ℃. In relation to the installation year (30 years), insulation resistance decreased from 70 ℃, which is as much as 40 ℃ lower than the result found by the accelerated test. Regarding the material properties, the longer the elapsed time since installation, the rougher the surface of conductor contact point was, and cracks increased. Conclusion: The 30-year-old electrical socket outlet exceeded the allowable temperature which is 65 ℃ of the electrical contacts at 10 A, and the insulation resistance began to decrease at 70 ℃. It is necessary to manage electrical socket outlets that have been installed for a long time.

• 의료ㆍ복지 건축 : 한국의료복지건축학회 논문집
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• 제27권4호
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• pp.41-50
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• 2021

Purpose: This study is aimed at the case of the cognitive health design pilot projects promoted by the Seoul Metropolitan Government since 2014 in terms of design to solve social problems in accordance with the aging population of our society. The purpose of this study is to analyze the maintenance and management of the projects and to suggest implications for the promotion and expansion of sustainable cognitive health design in the future. Method: It set the analysis frame by dividing management into maintenance-damage-demolition for the spatial types and spatial elements suggested in the Seoul Cognitive Health Guidelines. And it analyze the actual conditions of four pilot projects based on the field survey. Results: First, the ratio of damage and demolition was higher than maintenance. Second, designs and techniques with low durability were applied. Most of the cases where floor marks were applied to the external environment were lost or difficult to recognize, and their functions were limited due to storage of goods and parking of vehicles and motorcycles. Third, there was a large variation according to the type of residence. The project contents that can be applied to the low-rise residential area were also limited, and more elements were demolished than in the apartment type. Implications: First, it should limit project contents of space types and space elements that can be maintained even over time. Second, it should seek sustainable design and technical solutions. Third, it should seek alternatives to cognitive health design in low-rise residential areas where a large number of elderly people live.

• Design & Manufacturing
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• 제16권4호
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• pp.52-59
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• 2022

Currently, Korea is an aging society and is expected to become a super-aged society in about four years. X-ray devices are widely used for early diagnosis in hospitals, and many X-ray technologies are being developed. The development of X-ray device technology is important, but it is also important to increase the reliability of the device through accurate data management. Sensor nodes such as temperature, voltage, and current of the diagnosis device may malfunction or transmit inaccurate data due to various causes such as failure or power outage. Therefore, in this study, the temperature, tube voltage, and tube current data related to each sensor and detection circuit of the diagnostic X-ray imaging device were measured and analyzed. Based on QC data, device failure prediction and diagnosis algorithms were designed and performed. The fault diagnosis algorithm can configure a simulator capable of setting user parameter values, displaying sensor output graphs, and displaying signs of sensor abnormalities, and can check the detection results when each sensor is operating normally and when the sensor is abnormal. It is judged that efficient device management and diagnosis is possible because it monitors abnormal data values (temperature, voltage, current) in real time and automatically diagnoses failures by feeding back the abnormal values detected at each stage. Although this algorithm cannot predict all failures related to temperature, voltage, and current of diagnostic X-ray imaging devices, it can detect temperature rise, bouncing values, device physical limits, input/output values, and radiation-related anomalies. exposure. If a value exceeding the maximum variation value of each data occurs, it is judged that it will be possible to check and respond in preparation for device failure. If a device's sensor fails, unexpected accidents may occur, increasing costs and risks, and regular maintenance cannot cope with all errors or failures. Therefore, since real-time maintenance through continuous data monitoring is possible, reliability improvement, maintenance cost reduction, and efficient management of equipment are expected to be possible.

• 보건행정학회지
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• 제33권1호
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• pp.40-54
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• 2023

Background: Based on the increase in the needs for convalescent rehabilitation medical services in Korea, this study aims to calculate the needs for rehabilitation services and examine its determinants for 229 regions. Methods: Claim data from the Health Insurance Review and Assessment Service were used to estimate patients who need to receive rehabilitation services, and data from various sources were also used for analysis. The number of cases and incidence rates of hospitalization related to convalescent rehabilitation were calculated to estimate the needs for services by region, and the results were visualized via a map. Multivariate regression and fixed effects regression using panel data were performed to identify the determinants of regional variation of the incidence rate. Results: First, the incidence rate of rural areas such as Jeolla-do, Gyeongsang-do, and Chungcheong-do was higher than urban areas (metropolitan cities). Second, the population, proportion of the elder, medical aid recipients, financial independence, traffic deaths, smoking, diabetes rate, and medical infrastructure correlated significantly with the incidence rate. Third, 'rho' values which mean the fraction of variance due to individual terms in panel data regression models were 0.965 and 0.976, respectively. Conclusion: The incidence rate of hospitalizations was correlated with most independent variables in this study and there is a gap between urban and rural areas. These regional disparities are fixed in our society. An improved regional convalescent rehabilitation system is suggested to cover the entire area including rural areas with a high rate of aging.

• 대한의용생체공학회:의공학회지
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• 제44권6호
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• pp.377-383
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• 2023

Purpose: There is increasing attention to the application of transcranial direct current stimulation (tDCS) for enhancing cognitive functions in subjects to aging, mild cognitive impairment (MCI), and Alzheimer's disease (AD). Despite varying treatment outcomes in tDCS which depend on the amount of current reaching the brain, there is no general information on the impacts of anatomical features associated with AD on tDCS-induced electric field. Objective: The objective of this study is to examine how AD-related anatomical variation affects the tDCS-induced electric field using computational modeling. Methods: We collected 180 magnetic resonance images (MRI) of AD patients and healthy controls from a publicly available database (Alzheimer's Disease Neuroimaging Initiative; ADNI), and MRIs were divided into female-AD, male-AD, female-normal, and male-normal groups. For each group, segmented brain volumes (cerebrospinal fluid, gray matter, ventricle, rostral middle frontal (RMF), and hippocampus/amygdala complex) using MRI were measured, and tDCS-induced electric fields were simulated, targeting RMF. Results: For segmented brain volumes, significant sex differences were observed in the gray matter and RMF, and considerable disease differences were found in cerebrospinal fluid, ventricle, and hippocampus/amygdala complex. There were no differences in the tDCS-induced electric field among AD and normal groups; however, higher peak values of electric field were observed in the female group than the male group. Conclusions: Our findings demonstrated the presence of sex and disease differences in segmented brain volumes; however, this pattern differed in tDCS-induced electric field, resulting in significant sex differences only. Further studies, we will adjust the brain stimulation conditions to target the deep brain and examine the effects, because of significant differences in the ventricles and deep brain regions between AD and normal groups.

• 한국자원식물학회지
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• 제30권5호
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• pp.522-534
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• 2017

다양한 환경에서 수집한 국내 민들레속 유전자원 수집종의 엽록체 DNA 영역(trnL-trnF와 rps16-trnK) 염기서열을 이용하여 종내 간 변이 및 배수성을 구명하여 유전자원 육성의 기초자료를 제공하고자 수행하였다. 민들레속 유전자원의 배수성은 털민들레, 서양민들레, 붉은씨서양민들레가 3배체이고, 흰민들레와 흰노랑민들레는 4배체였다. 염기서열의 길이는 trnLtrnF 영역에서 자생종류인 털민들레, 흰민들레, 흰노랑민들레가 931 bp에서 935 bp, 서양민들레는 910 bp, 붉은씨서양민들레는 975 bp로 종간 차이를 나타내었고, 종 특이적 염기서열 88개, 자생종 및 귀화종 특이적 염기서열 41개가 검출되었다. rps16-trnK 영역은 털민들레 882~883 bp, 흰민들레 875~881 bp, 흰노랑민들레는 878~883 bp 서양민들레 874~876 bp, 붉은씨서양민들레는 847~848 bp로 37개 종특이적 염기서열이 검출되었다. 염기서열의 유사도는 trnL-trnF 영역에서 0.860~1.000 사이로 평균 0.949이며, rps16-trnK 영역의 유사도는 0.919~1.000 사이로 평균 0.967이었다. 염기서열을 바탕으로 유연관계를 분석한 결과, trnL-trnF 영역은 크게 자생종류와 귀화종류로 구분되었으며, 서양민들레와 붉은씨서양민들레는 같은 종간에 유집되었고, 자생종류는 분리되지 않았으며, rps16-trnK 4개 그룹과 유집되지 않은 5개체로 나뉘었다. 흰노랑민들레는 두 영역 모두 흰민들레와 동일 계통군을 형성하였고, 염기서열상 두 종간 뚜렷한 차이가 없었다. 유연관계에서 모두독립적으로 존재한 흰민들레 No. 10 (조계산)과 털민들레 1번(광양)은 민들레 유전자원 육성소재로 활용이 기대된다.