• Proceedings of the Korean Geotechical Society Conference
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• 2008.03a
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• pp.1431-1437
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• 2008

The small-strain shear modulus ($G_{max}$) of uncemented sand is affected by the the mean principal stress and void ratio, and it has been known that the cementation and aging also affect to $G_{max}$ of sand. For extensive understanding about the effect of cementation on the $G_{max}$ of sand, a series of bender element tests was conducted on the cemented specimens prepared in a large calibration chamber by pluviation of the sand-gypsum mixture. It was observed from the experimental results that the $G_{max}$ of cemented sand is higher above 10 times than value of uncemented one, and it increases exponentially with the gypsum content increases. Whereas, the increase of the vertical stress from 50kPa to 200kPa and the relative density from 40% to 80% result in 20~30% and 2 times increase of $G_{max}$, respectively. It means that the gypsum content, that is cementation level, is the most influential factor on the $G_{max}$ of cemented sand. In addition, the effect of relative density on $G_{max}$ was more apparent on cemented sand than uncemented one.

• Journal of the Korean Home Economics Association
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• v.44 no.5 s.219
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• pp.157-169
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• 2006

The purpose of this study was to verify the effectiveness of a life review-narrative group therapy program aimed at increasing ego-integrity in the elderly. The life review-narrative group therapy program was organized according to the tfe course from childhood to old age. The objectives of the program were for the elderly to enhance their self-worth, become aware of their individual self existence, accept aging and death, accept the past and present life, and to make the most of their experiences of overcoming difficulties. The counseling techniques used in the program were mainly reminiscence and re-authoring of the narrative therapy. Thirty-two elderly people aged 60 years and over (16 in each of experimental and control groups) were selected randomly from the Daegu Metropolitan City General Welfare Center for the research. The two groups were identified as equivalent for the study in a pre-test. The program of the experimental group was implemented twice a week for 90 minutes per session over a 6-week period (Sep. 8th - Oct. 14th. 2005). The pre (Sep. 8th 2005), the post (Oct. 14th. 2005) and follow-up (Nov. 14th. 2005) tests were implemented in ordo, to verify the effectiveness of the program. The instruments used in the study were the Ego-Integrity Scale. The data were analyzed using t-test, and Ore-Factor Repeated Measures ANOVA. The findings of the study were as follows. The experimental group evidenced significant effects on enhancing ego-integrity. The result of the post hoc multiple comparisons showed that the effects of the life review-narrative group therapy Program were maintained for one months. Meanwhile the control group did not show any significant change in ego-integrity. Based on these findings, the limitations of the study were discussed, and further research was suggested.

• Journal of Gastric Cancer
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• v.11 no.2
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• pp.116-121
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• 2011

Purpose: Gastric cancer surgery is a common operation in East Asia, such as Korea and Japan, and there has been a significant increase in the need for this procedure due to the aging population. As a result, surgery for the treatment of gastric cancer for elderly patients is expected to increase. This study examined the effect of old age on gastric cancer surgery, and analyzed the operative risk factors for elderly patients. Materials and Methods: From November 2008 to August 2010, 590 patients, who underwent a curative resection for gastric cancers, were enrolled. Patients who underwent palliative or emergency surgery were excluded. A retrospective analysis of the correlation between surgical outcomes and age was performed. The elderly were defined as patients who were over the age of 65 years. Results: The mean age of all patients was 58.3 years, and complications occurred in 87 cases (14.7%). The most common complication was wound infection and severe complications requiring surgical, endoscopic, or radiologic intervention developed in 52 cases (8.8%). The rate of complications increased with increasing age of the patients. Univariate analysis revealed age, comorbidity, extent of resection, operation time, and combined resection to be associated with surgical complications. In particular, age over 75 years old, operation time, and comorbidity were predictive factors in multivariate analysis. In the elderly, only comorbidity was associated with surgical complications Conclusions: The patients' age is the most important factor for predicting surgical complications. Surgeons should pay an attention to the performance of gastric cancer surgery on elderly patients. In particular, it must be performed carefully for elderly patients with a comorbidity.

• Speech Sciences
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• v.15 no.3
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• pp.95-102
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• 2008

Multiple physical changes of the larynx and its components occur with age. Vocal pitch, commonly expressed through measures of fundamental frequency (Fo) relate to physical conditions of the larynx. Available data is lacking for the senescent voice, and should be applied to the of changes of elderly speakers' Fo characteristics. The purpose of this study was to investigate the Fo of normal elderly speaker's voice. A total of 406 normal elderly speakers (207 males and 199 females) participated in this experiment. Age ranged from 60 years to 89 years. The subjects were asked to produce sustained corner vowels (/a/ /i/ /u/) three times each and the data were analyzed using the MDVP of CSL. According to the results of this study, the mean Fo from the ages of 60's to 80's shows 143.95Hz(SD 13.94) for men and 185.42Hz (SD 15.29) for women. For men, a significant change is found as a function of age in the Fo (F=16.181, p<.05). A post-hoc Scheffe test revealed significant differences between the Fo data of subjects aged 60's and 70's, 60's and 80's. For women, a significant change is found as a function of age in the Fo (F=49.013, p<.05). A post-hoc $Scheff'{e}$ test revealed significant differences between the Fo data of subjects in their 60's and 70's, 70's and 80's, 60's and 80's. The Fo of men goes up from their 60's to 80's gradually, whereas the Fo of women goes down gradually until their 70's, and after their 70's it again increases. It has been known that diminishing estrogen levels in women in old age may be a factor in lowering Fo, whereas diminishing testosterone levels in men may contribute to a rising Fo. This result may be used as some meaningful guideline and lead the basic data to differentiate between normal aged voice and aged voice disorders.

• The Korean Journal of Ecology
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• v.23 no.2
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• pp.83-88
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• 2000

When interpreting change over time in forest ecosystems, distinguishing the effects of forest succession from the effects of environmental stress can be difficult. The result may be a simplistic interpretation. citing a specific successional or environmental cause of forest change when both types may be occurring. We present two case studies of changes in the forest floor in northern hardwoods. First, the belief that 50% of soil organic matter is lost in the first 20 years after logging was based on a study comparing northern hardwood stands of different ages. We resampled a series of 13 such stands after an interval of 15 years, and found that the young stands were not, in fact. losing organic matter as rapidly as predicted from the original chronosequence study. The pattern of higher organic matter content in the forest floors of older stands compared to young stands could be equally well explained by changes in logging practices over the last century as by the aging of the stand. The observed pattern of forest floor organic matter as a function of stand age was previously interpreted as a successional pattern, ignoring changes in treatment history. In the second case study, observed losses of base cations from the forest floor were attributed to cation depletion caused by acid rain and declining calcium deposition. We found that young stands were gaining base cations in the forest floor; losses of base cations were restricted to older stands. Differences in litter chemistry in stands of different ages may explain some of the pattern in cation gains and losses. In this case, the contribution of successional processes to cation loss had been overlooked in favor of environmental stress as the dominant mechanism behind the observed changes. Studies of environmental stress use repeated measures over time. but often don't consider stand age as a factor. Studies of successional change often assume that environmental factors remain constant. We were able to consider both forest succession and external factors because we repeatedly sampled stands of different ages.

• BMB Reports
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• v.38 no.5
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• pp.545-549
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• 2005

Acidithiobacillus ferrooxidans is one of the most important bacterium used in bioleaching, and can utilize $Fe^{2+}$ or sulphide as energy source. Growth curves for Acidithiobacillus ferrooxidans under phosphate starvation and normal condition have been tested, showing lag, logarithmic, stationary and aging phases as seen in other bacteria. The logarithmic phases were from 10 to 32 hours for Acidithiobacillus ferrooxidans cultivated with normal cultivating condition and from 20 to 60 hrs for Acidithiobacillus ferrooxidans cultivated phosphate starvation. Differences of protein patterns of Acidithiobacillus ferrooxidans growing in case of normal or phosphate starvation were separately investigated after cultivation at $30^{\circ}C$ by the analysis of two-dimensional gel electrophoresis (2-DE), matrix-assisted laser desorption/ionization (MALDI)-Mass spectrometry. There were total 6 protein spots identified, which were Recombination protein recA, RNA helicase, AP2 domain-containing transcription factor, NADH dehydrogenase I chain D, Hyothetical protein PF1669, and Transaldolase STY3758. From the 6 identified protein spots, 3 proteins were found to be decreased in expression at the cultivating condition of phosphate starvation, while another three upregulated.

• Molecules and Cells
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• v.27 no.3
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• pp.291-297
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• 2009

Apolipoprotein (apo) C-III is a marker protein of triacylglycerol (TG)-rich lipoproteins and high-density lipoproteins (HDL), and has been proposed as a risk factor of coronary heart disease. To compare the physiologic role of reconstituted HDL (rHDL) with or without apoC-III, we synthesized rHDL with molar ratios of apoA-I:apoC-III of 1:0, 1:0.5, 1:1, and 1:2. Increasing the apoC-III content in rHDL produced smaller rHDL particles with a lower number of apoA-I molecules. Furthermore, increasing the molar ratio of apoC-III in rHDL enhanced the surfactant-like properties and the ability to lyse dimyristoyl phosphatidylcholine. Furthermore, rHDL containing apoC-III was found to be more resistant to particle rearrangement in the presence of low-density lipoprotein (LDL) than rHDL that contained apoA-I alone. In addition, the lecithin:cholesterol acyltransferase (LCAT) activation ability was reduced as the apoC-III content of the rHDL increased; however, the CE transfer ability was not decreased by the increase of apoC-III. Finally, rHDL containing apoC-III aggravated the production of MDA in cell culture media, which led to increased cellular uptake of LDL. Thus, the addition of apoC-III to rHDL induced changes in the structural and functional properties of the rHDL, especially in particle size and rearrangement and LCAT activation. These alterations may lead to beneficial functions of HDL, which is involved in anti-atherogenic properties in the circulation.

• Molecules and Cells
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• v.37 no.7
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• pp.554-561
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• 2014

Lysophosphatidic acid (LPA) is a lipid growth factor that exerts diverse biological effects through its cognate receptors ($LPA_1-LPA_6$). $LPA_1$, which is predominantly expressed in the brain, plays a pivotal role in brain development. However, the role of $LPA_1$ in neuronal migration has not yet been fully elucidated. Here, we delivered $LPA_1$ to mouse cerebral cortex using in utero electroporation. We demonstrated that neuronal migration in the cerebral cortex was not affected by the overexpression of $LPA_1$. Moreover, these results can be applied to the identification of the localization of $LPA_1$. The subcellular localization of $LPA_1$ was endogenously present in the perinuclear area, and overexpressed $LPA_1$ was located in the plasma membrane. Furthermore, $LPA_1$ in developing mouse cerebral cortex was mainly expressed in the ventricular zone and the cortical plate. In summary, the overexpression of $LPA_1$ did not affect neuronal migration, and the protein expression of $LPA_1$ was mainly located in the ventricular zone and cortical plate within the developing mouse cerebral cortex. These studies have provided information on the role of $LPA_1$ in brain development and on the technical advantages of in utero electroporation.

• Fashion & Textile Research Journal
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• v.17 no.6
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• pp.932-941
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• 2015

An aging population and increasing consumer demand for high-quality and innovative new products are key drivers for growth in the cosmeceutical industry. Cosmeceuticals are defined as products with biologically active ingredients that have a measurable effect on the user. This study explored the effects of shopping orientation and store attributes on impulse buying behavior for cosmeceuticals. We obtained 437 usable questionnaires from university students who had purchased cosmeceutical products. Data analysis was conducted using confirmatory factor analysis and structural equation modeling analysis via AMOS 18.0. The findings were: 1) hedonic shopping orientation and convenience shopping orientation had positive effects on product efficacy and promotion of the cosmeceutical store 2) brand shopping orientation had a positive effects on store atmospheric, skin care service, and brand of the cosmeceuticals store and 3) product efficacy and promotion of store attributes had a direct effect on impulse buying behavior for cosmeceuticals. Consumers who tended to enjoy the shopping to refresh themselves and to experience convenient shopping were likely to purchase cosmeceuticals impulsively, which mediated by the store attributes (product efficacy and promotion). Therefore, we confirmed partly causal relationships among the shopping orientation, store attributes, and impulse buying behavior of cosmeceuticals. Both managerial and theoretical implication for practitioners and researchers were discussed for managing product information more efficiently along with promotion strategies to trigger cosmeceuticals consumers in the context of shopping.

• The Journal of Society for e-Business Studies
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• v.21 no.4
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• pp.95-117
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• 2016

Entering aging society and increasing individual's interests on wellbeing lead to increasing demands of healthcare service and various healthcare related applications are providedon app market or Internet. These healthcare services could enhance user's health status if the users continuously use the service. In order to enhance effectiveness of a healthcare service, the service user should comply with recommendations or directions are provided by the service. However, previous studies of healthcare service are not considered effects of compliance intention on continuous usage. Hence, we tested how user's compliance intention effect on continuous usage intention of healthcare service based on theories of information system and medical information. Moreover, we found that compliance intention of users for healthcare service is an important factor on sustainability of healthcare service. Additionally, we investigated what factors are related with user's compliance intention.