• Title/Summary/Keyword: ages

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Screening of Korean Herbal Medicines with Inhibitory Activity on Advanced Glycation End Products Formation (VII) (한국약용식물의 최종당화산물 생성저해활성 검색(VII))

  • Choi, So-Jin;Kim, Young Sook;Song, Yoo Jin;Lee, Yun Mi;Kim, Joo Hwan;Kim, Jin Sook
    • Korean Journal of Pharmacognosy
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    • v.43 no.4
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    • pp.345-351
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    • 2012
  • In this study, 49 Korean herbal medicines have been investigated with an in vitro evaluation system using glycation end products (AGEs) formation inhibitory activity. Of these, 18 herbal medicines ($IC_{50}$ < $50{\mu}g/ml$) were found to have significant AGEs formation inhibitory activity. Of these, five herbal medicines ($IC_{50}$ < $50{\mu}g/ml$) were found to have significant AGEs formation inhibitory activity. Particularly, Mallotus japonicus (twigs and leaves), Rhus javanica (twigs and leaves), Boehmeria nivea (whole plants), Quercus acuta (stems), and Eurya japonica (stems) showed more potent inhibitory activity (approximately 9-37 fold) than the positive control aminoguanidine ($IC_{50}=76.47{\mu}g/ml$).

A Study on the Women's Preference to the Skirt Design (성인 여성의 스커트 디자인선호에 관한 연구)

  • 기희숙;서미아
    • The Research Journal of the Costume Culture
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    • v.2 no.1
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    • pp.123-143
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    • 1994
  • The aim of this research analyze women's preference in types and formation of skirt lines by their ages and body shapes. The aim of this study is for women to select clothing which can cover their shortcomings and to present the practical and positive data about skirt design to clothing maker. The results of this research are summarized as followed : Tight skirt is the beest preferred and flare is the next. Narred silhouettes re preferred about th width of each kind of skirt, but as for the gored and flare skirts middle-width silhouettes are preferred. Preferred lengths of the skirts are different from ages; the middle like minilines, the thirties like miniline, the thirties and the forties natural line, and the fifties midiline, and according to body shapes, the skinny or standard shape like natural line and the fat midiline. All age prefer natural waist line, and twenties and the skinny like high waist line and belt compared to fifties and the fat. All ages like dart-treated skirt waist and wrinkle-decoration with narrow vertical lines or tuck-decoration with narrow horizontal line. White and blue are preferred colors of skirts in spring and summer, the skinny and the standard like blue, whereas the fat like black. All ages like soft materials and one-colored skirts without patterns Adult women like jipper to open waist of a skirt. Most of them like back positioned one, but fifties and the fat prefer side positioned ones.

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A Study of Spheric and Add Power on Presbyopia (노안의 굴절력 분포와 근용가입도에 대한 연구)

  • Yoon, Kyoung Han
    • Journal of Korean Ophthalmic Optics Society
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    • v.5 no.2
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    • pp.115-118
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    • 2000
  • In this study, to valuate the visual acuity of presbyopia, the study was researched by the amplitude accomodation method. The major findings was as follows : 1. The add power was ranged from +0.50 Dptr to +4.00 Dptr. 2. Add power ${\leq}$+1.00 Dptr was measured in 38~44 ages. 3. The +1.25 Dptr ${\leq}$ Add powers ${\leq}$ +2.00 Dptr was measured in 45~50 ages. 4. The +1.50 Dptr ${\leq}$ Add power ${\leq}$ +3.00 Dptr was measured in 51~55 ages. 5. The +2.50 Dptr ${\leq}$ Add power ${\leq}$ +4.00 Dptr was measured in 56~65 ages. 6. They put on their glasses for near purpose in 60%.

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A Study on Dietary Status of Elderly Koreans with Ages (전북 일부지역(무주군) 노인의 연령에 따른 식생활 실태조사 연구)

  • 장혜순;김미라
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.28 no.1
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    • pp.265-273
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    • 1999
  • Elderly Koreans living in Muju Gun, Jeonbuk were divided into two groups with ages(65~74 years old group & over 75 years old group) and surveyed with questionnaire to investigate their dietary status and those factors affected with ages. The score of food habit in both sexes showed a falling tendency as their ages increased. Compared with elderly men, elderly women showed lower quality of diet. Elderly Korean were more consumed cereals and green vegetables than milk, egg, meat & fish, seaweed and fats & oils. As education level increased, the food habit score showed a rising tendency. The correlation coefficient between the score of food habit and education level was positive in illiterate and school graduates. The score of food habit of living together with their family was higher than those of living alone or living with their spouse. As household income increased, the food habit score showed a rising tendency. In the case of self consciousness of socioeconomic status was middle, food habit score is higher than those of very low. Dental status of eldery people did not affect food habit score. Palatability showed no significant correlation with age. Elderly Koreans prefered sweet taste than salty, sour, and bitter taste.

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Constituents of the Roots of Pueraria Iobata Inhibit Formation of Advanced Glycation End Products (AGEs)

  • Kim, Jong-Min;Lee, Yun-Mi;Lee, Ga-Young;Jang, Dae-Sik;Bae, Ki-Hwan;Kim, Jin-Sook
    • Archives of Pharmacal Research
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    • v.29 no.10
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    • pp.821-825
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    • 2006
  • Two isoflavone C-glucosides, puerarin (1) and PG-3 (2), a but-2-enolide, $({\pm})-puerol$ B (3), two isoflavone O-glucosides, daidzin (4) and genistin (5), and three pterocarpans, (-)-medicarpin (6), (-)-glycinol (7) and (-)-tuberosin (8), were isolated from a MeOH extract of the roots of Pueraria Iobata, using an in vitro bioassay based on the inhibition of the formation of advanced glycation end products (AGEs) to monitor chromatographic fractionation. The structures of 1-8 were determined by spectroscopic data interpretation, particularly by 1D- and 2D-NMR studies, and by comparison of these data with values in the literature. All of the isolates (1-8) were evaluated for their inhibitory activity on AGEs formation in vitro. Of these, puerarin (1), PG-3 (2), and $({\pm})-puerol$ B (3) exhibited more potent inhibitory activity than the positive control aminoguanidine.

A Study on the Lilfestyle types of the Middle Ages and Senior Housing Characteristics (중년층의 라이프스타일 유형 및 노인주거 특성에 관한 연구)

  • Yoon, Chung-Sook;Kim, Han-Na;Shin, Soo-Young;Kang, Ji-Hye
    • Journal of the Korean housing association
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    • v.18 no.4
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    • pp.9-15
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    • 2007
  • Recently elderly has been recognized as a healthy and active generation because of extended average life span by medical development, interests in health, and achieved economic power while elderly was regarded as a passive and dependant generation before. The primary purpose of this study was to analyze the lifestyle types and housing consciousness of the middle ages around fifty's who will have more inclinations in the future to consider the hosing problems of elderly. To collect the data, LOV survey method was used for 600 middle ages about their lifestyles and future housing types. The data analysis used SPSS PC 12.0 to find the frequency, chi-square, factor analysis, and cluster analysis. The results of analysis are as follows: First, the lifestyle was segmented into five groups and there were differences on demographics such as education and income, also on housing sizes and types of home-ownership types. Second, there were different preferences on the types of senior housing by different lifestyles whereas there were similar on the location and sizes of houses by different clusters.

Investigation of Flexural Toughness Development of Steel Fiber Reinforced Concrete at Early Ages (강섬유 보강 콘크리트의 조기 재령에서의 휨 인성 발현에 관한 연구)

  • Lee, Chang-Joon;Shin, Sung-Woo
    • Journal of the Korean Society of Safety
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    • v.24 no.6
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    • pp.103-110
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    • 2009
  • Since the mechanical properties of cement-based materials are time-dependent due to the prolonged cement hydration process, those of fiber reinforced concrete(FRC) may also be time-dependent. Toughness is one of important properties of FRC. Therefore, it should be investigated toughness development of FRCs with curing ages to fully understand the time-dependent characteristics of FRCs. To this end, the effect of curing ages on flexural toughness development of steel fiber reinforced concrete is studied. Three point bending test with notched beam specimen was adapted for this study. Hooked-end steel fiber(DRAMIX 40/30) was used as a fiber ingredient to investigate w/c ratio and fiber volume fraction effect on toughness development during curing. Three different water-cement ratios(0.44, 0.5 and 0.6) and fiber volume fractions(0%, 0.5% and 1%) were used as influence factors. Each mixture specimens were tested at five different ages, 0.5, 1, 3, 7 and 28 days. The study shows that flexure toughness development with age is quite different than other concrete material properties such as compressive strength. The study also shows that the toughness development trend correlates more closely to water/cement ratio than to fiber volume fraction.

Cyclic load experiment study on the laminated composite RC walls with different concrete ages

  • Zhang, Hongmei;Lua, Xilin;Li, Jianbao;Liang, Lin
    • Structural Engineering and Mechanics
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    • v.36 no.6
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    • pp.745-758
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    • 2010
  • 12 typical laminated composite reinforced concrete (RC) walls with different concrete ages and 3 cast-in-place RC walls subjected to low frequency cyclic load were carried out in this study. The failure mode, force-deformation response and energy dissipation capacity of these specimens were investigated. Differences of structural behaviours between composite RC walls and common cast-in-place RC walls were emphasized in the analysis. The compatibility of the composite specimens with different concrete ages was discussed based on the experiment. Test results indicated that the differences between the lateral bearing capacity and the displacement ductility of the composite walls and the common walls were not so obvious. Some of the composite specimen even has higher bearing capacity under the experiment loading situation. Besides, the two parts of the laminated composite specimens demonstrates incompatibility at the later loading sequence on failure mode and strain response when it is in tension. Finally, this laminated composite shear walls are suggested to be applied in rapid reconstruction structures which is not very high.

Constituents of the Stems of Rumex japonicus with Advanced Glycation End Products (AGEs) and Rat Lens Aldose Reductase (RLAR) Inhibitory Activity

  • Kim, Jong-Min;Lee, Yun-Mi;Jang, Dae-Sik;Kim, Jin-Sook
    • Journal of Applied Biological Chemistry
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    • v.49 no.1
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    • pp.24-27
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    • 2006
  • Four ursane-type triterpenoids, 2${\alpha}$,3${\alpha}$,19${\alpha}$-trihydroxy-24-norurs-4(23),12-dien-28-oic acid (1), 4(R),23-epoxy-2${\alpha}$,3${\alpha}$,19${\alpha}$-trihydroxy-24-norurs-12-en-28-oic acid (2), myrianthic acid (3), and tormentic acid (4), and a phenolic compound, ethyl gallate (5), from an EtOAc-soluble extract of the stems of Rumex japonicus, were subjected to in vitro bioassays to evaluate advanced glycation end products (AGEs) and rat lens aldose reductase (RLAR) inhibitory activity. Compounds 1 and 5 exhibited a significant inhibitory activity on AGEs formation with $IC_{50}$ value of 87 ${\mu}M$ and on RLAR with $IC_{50}$ value of 14.3 ${\mu}M$, respectively. Ethyl gallate (5) was isolated for the first time from this plant.

Screening of Korean Herbal Medicines with Inhibitory Activity on Advanced Glycation End Products Formation (IX) (한국약용식물의 최종당화산물 생성저해활성 검색 (IX))

  • Lee, Yun Mi;Kim, Young Sook;Kim, Joo Hwan;Kim, Jin Sook
    • Korean Journal of Pharmacognosy
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    • v.44 no.3
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    • pp.298-304
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    • 2013
  • In this study, 64 Korean herbal medicines have been investigated with an in vitro evaluation systems using glycation end products (AGEs) formation inhibitory activity. Of these, 30 herbal medicines ($IC_{50}&lt;50{\mu}g/ml$) were found to have significant AGEs formation inhibitory activity. Of these, four herbal medicines ($IC_{50}&lt;5{\mu}g/ml$) were found to have significant AGEs formation inhibitory activity. Particularly, Cornus controversa (branches and leaves), Acer ginnala (stems and leaves), Platycarya strobilacea (flowers) and Picrasma quassioides (stems), showed more potent inhibitory activity (approximately 17-27 fold) than the positive control aminoguanidine ($IC_{50}=77.04{\mu}g/ml$).