• Biomedical Science Letters
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• v.11 no.2
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• pp.143-152
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• 2005

To investigate the exposure effect of polycyclic aromatic hydrocarbons (PAHs), we analyzed the relationship between urinary 8-hydroxydeoxyguanosine (8-OHdG) concentration and PAHs exposure. The study population contained 44 workers in steel-pipe coating and paint manufacture industries. We measured airborne total PAHs as an external dose, urinary 1-hydroxypyrene (1-OHP) as an internal dose of PAHs exposure, and urinary 8-OHdG as an effective dose of oxidative DNA damage. There was significant correlation between the urinary concentration of l-OHP and the environmental concentration of PAHs, pyrene, urinary cotinine, AST, and GGT. The mean of urinary 8-OHdG was $17.07\pm1.706{\mu}g/g$ creatinine in workers exposed to airborne PAHs. There was significant correlation between the urinary concentration of 8-0HdG and the airborne concentration of PAHs. From the results of stepwise multiple regression analysis about 8-OHdG, significant independents was total PAHs. In this study, there were significant correlation between the urinary concentration of 8-OHdG and the airborne concentration of PAHs. The urinary 1-OHP was effective index as a biomarker of airborne PAHs in workplace. But it was influenced by non-occupational PAHs source, smoking and biomarkers of liver function test.

• Food Science of Animal Resources
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• v.38 no.3
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• pp.442-450
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• 2018

Liquid egg products can be contaminated with Salmonella spp. during processing. A predictive model for the growth of Salmonella spp. in unpasteurized liquid eggs was developed and validated. Liquid whole egg, liquid yolk, and liquid egg white samples were prepared and inoculated with Salmonella mixture (approximately 3 Log CFU/mL) containing five serovars (S. Bareilly, S. Richmond, S. Typhimurium monophasic, S. Enteritidis, and S. Gallinarum). Salmonella growth data at isothermal temperatures (5, 10, 15, 20, 25, 30, 35, and $40^{\circ}C$) was collected by 960 h. The population of Salmonella in liquid whole egg and egg yolk increased at above $10^{\circ}C$, while Salmonella in egg white did not proliferate at all temperature. These results demonstrate that there is a difference in the growth of Salmonella depending on the types of liquid eggs (egg yolk, egg white, liquid whole egg) and storage temperature. To fit the growth data of Salmonella in liquid whole egg and egg yolk, Baranyi model was used as the primary model and the maximum growth rate and lag phase duration for each temperature were determined. A secondary model was developed with maximum growth rate as a function of temperature. The model performance measures, bias factor ($B_f$, 0.96-0.99) and $r^2$ (0.96-0.99) indicated good fit for both primary and secondary models. In conclusion, it is thought that the growth model can be used usefully to predict Salmonella spp. growth in various types of unpasteurized liquid eggs when those are exposed to various temperature and time conditions during the processing.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.41 no.12
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• pp.1002-1010
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• 2013

Intercom System(ICS) of Korean Utility Helicopter(KUH) is an essential equipment for pilot to perform flight mission and it consists of communication system of KUH with VHF-FM radio set and U/VHF-AM radio set. It provides pilots and crews with internal communication, external communication and audible alarm. It has function of controlling volume and selecting two communication modes, normal mode and backup mode. This paper summarizes pilot comments in flight test which are classified by cause of occurrence and the troubleshooting process about each comment. It also describes design improvements which was derived from troubleshooting and suggests verification results of flight test.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.26 no.6
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• pp.555-563
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• 2015

This paper presents signal processing algorithms of a frequency-modulated continuous-wave(FMCW) radar altimeter and provides a practical assessment technique. The radar altimeter is initially operated in search mode, when the radar altimeter detects a valid altitude, search mode is switched to track mode and a altitude being tracked is displayed. The sweep bandwidth in each mode is a function of altitude to narrow the beat frequency bandwidth. In addition, transmit power and receiver gain in each mode are controlled to compensate for the dynamic range of wide altitude range. To assess more realistic operation, the radar altimeter was tested using the crane setup. The crane test demonstrated that signal processing algorithms described in this paper resulted in a reduced measurement error rate.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.25 no.2
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• pp.223-234
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• 2014

This paper describes the analysis results of channel characteristics in the operating area of satellite OTM(On-The-Move) terminal. The communication channel between the Koreasat-5 and OTM terminal on a test car is measured and recorded from Daejeon to Daecheon, using the downlink frequency of around 20 GHz. And the measurement data are divided into two classes ; highway environment and national road environment, and then are statistically analyzed. The statistical evaluation of satellite channel is conducted by using probability density function and Markov model and then presents average connection duration(ACD), average fade duration( AFD), and level crossing rate(LCR) of highway environment and national road environment. Finally the statistics data of the two environments are compared with each other.

• Journal of Veterinary Clinics
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• v.36 no.1
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• pp.1-6
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• 2019

This study reviewed the trends and prospect of the market for veterinary medical devices in Korea. The registration of veterinary medical devices has sharply increased since 2013, and a total of 2,133 products from 348 companies were registered by 2018. Of these products, the proportion of the instrument, in vitro diagnostic (IVD) reagents, medical only used for animal and supplies were 51.6%, 35.7%, 7.6% and 5.1%, respectively. The sales amount of veterinary medical devices is approximately 95.8 billion won in 2017. The sales of domestic consumption and imports were 53.9 and 41.9 billion won, respectively. They are increasing 14.9% (CAGR) in the domestic consumption, and 44.0% (CAGR) in the export from 2011 to 2017, respectively. The proportion of IVD reagents, instrument, medical only used for animal and supplies were 54.2%, 41.0%, 3.8%, and 1.0%, respectively. The top 10 items with high sales were IVD reagents for clinical immunochemistry, visceral function testing instrument, hematological testing apparatus, syringes, IVD reagents for molecular genetics, etc. They are widely used from 3,926 animal hospitals in 2017. This study suggested that registration and sales of veterinary medical devices have gradually increased since 2013 as the demand of health care services for various animals. Therefore, the veterinary medical devices industry is expected to grow in the future.

• Microbiology and Biotechnology Letters
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• v.44 no.3
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• pp.383-390
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• 2016

Mesenchymal stem cells (MSCs) are multipotent stem cells that can be differentiated into a variety of cell types, including adipocytes, osteoblasts, chondrocytes, β-pancreatic islet cells, and neuronal cells. MSCs have been reported to exhibit immunomodulatory effects in many diseases. Many studies have reported that MSCs have distinct roles in modulating inflammatory and immune responses by releasing bioactive molecules. Exosomes are cell-derived vesicles present in biological fluids, including the blood, urine, and cultured medium of cell cultures. In this study, we investigated the immunomodulatory effects of mouse adipose tissue-derived MSCs (mAD-MSCs), cultured medium (MSC-CM) of mAD-MSCs, and mAD-MSC-derived exosomes (MSC-Exo) on lipopolysaccharide (LPS)-induced RAW 264.7 cells. We observed that the expression levels of IL-1β, TNF-α, and IL-10 were significantly increased in LPS-stimulated RAW 264.7 cells compared to those in LPS-unstimulated RAW 264.7 cells. Additionally, these values were significantly (p < 0.05) decreased in mAD-MSCs-RAW 264.7 cell co-culture groups, MSC-CM-treated groups, and MSC-Exo-treated groups. MSCs can modulate the immune system in part by secreting cytokines and growth factors. We observed that immunomodulatory factors such as IL-1β, TNF-α, and IL-10 were secreted by mAD-MSCs under co-culturing conditions of mAD-MSCs with activated RAW 264.7 cells. In addition, mAD-MSC-derived exosomes exhibited similar immunomodulatory effects in activated RAW 264.7 cells. Therefore, our results suggest that mAD-MSCs have an immunomodulatory function through indirect contact.

• Proceedings of the KIEE Conference
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• 1999.07b
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• pp.656-658
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• 1999

This paper presents musculotendon model to show the decline in muscle force during functional electrical stimulation (FES). It represent muscle activation and contraction concepts including muscle fatigue. A muscle fatigue term in activation dynamics as a function of the intracellular acidification and the pulsewidth of stimulation pulses change activation to decline muscle force. The computer simulation shows that muscle force decline in stimulation time.

• 제어로봇시스템학회:학술대회논문집
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• 1998.10a
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• pp.352-355
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• 1998

A musculotendon model is investigated to show muscle fatigue under the repeated functional electrical stimulation (FES). The normalized Hill-type model can predict the decline in muscle force. It consists of nonlinear activation and contraction dynamics including physiological concepts of muscle fatigue. A muscle fatigue as a function of the intracellular acidification, pHi is inserted into contraction dynamics to estimate the force decline. The computer simulation shows that muscle force declines in stimulation time and the change in the estimate of the optimal fiber length has an effect only on muscle time constant not on the steady-state tetanic force.

• International Journal of Advanced Culture Technology
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• v.6 no.4
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• pp.262-265
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• 2018

Deep learning, a sub-field of machine learning changing the prospects of artificial intelligence (AI) because of its recent advancements and application in various field. Deep learning deals with algorithms inspired by the structure and function of the brain called artificial neural networks. This works reviews basic architecture and recent advancement of deep structured learning. It also describes contemporary applications of deep structured learning and its advantages over the treditional learning in artificial interlligence. This study is useful for the general readers and students who are in the early stage of deep learning studies.