• Title/Summary/Keyword: adverse reaction

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THE EFFECT OF PRE-OPERATIVE STEROID INJECTION ON THE RELIEF OF COMPLAINT AFTER THIRD MOLAR SURGERY (술 전 스테로이드 투여가 하악 매복 제 3 대구치 발치 후 예상되는 불편감에 미치는 영향)

  • Kim, Sung-Dae;Kim, Kyung-Wook
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.29 no.3
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    • pp.157-162
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    • 2003
  • Background : The surgical removal of impacted mandibular third molar can result in considerable pain, swelling, and dysfunction that patient are incapable of work for several days. Factors contributing to post operative swelling, trismus and pain are complex. There is no question but that the procedure of surgically removing an impacted mandibular third molar is inherently a traumatic one and that some sequelae related to the inflammation response are expected. Meticulous surgical technique will minimize the sequelae of inflammation but will not prevent them. In an effort to minimize these sequelae the use of steroid was instituted. Patients and Methods : Present study was to investigate the effect of one preoperative steroid injection in the masseter muscle to the patients(male 9, female 11) who needed prophylactic removal of bilateral, symmetrical, impacted wisdom teeth in the mandible on the complaint like swelling, trismus and pain. through Double-Blind test. Results : 1. After 24 hours investigation, preoperative steroid injection had significantly reduced swelling with 39% and trismus with 57.5%. 2. $7^{th}$ post operative day investigation, reduced swelling and trismus had shown, however, not significant. 3. There wasn't major difference from the group who took preve-ntive steroid in the visual analogue scale, the first analgesic intake time and the pain period. 4. There wasn't any adverse reaction of steroid for 20 patient From the above result, If the patients are not contraindication to steroid and pronounced post operative reaction can be expected the use of steroid to the surgical removal of impacted mandibular third molar is recommended.

Degradation Characteristics of Aqueous MEA Solution by Corrosion Products and Absorption Conditions (흡수 조건 및 부식 생성물에 의한 MEA 수용액의 변성 특성)

  • NAM, SUNGCHAN;SONG, YOONAH;BAEK, ILHYUN;YOON, YEOIL;YOU, JEONGKYUN;LEE, CHANGHA
    • Transactions of the Korean hydrogen and new energy society
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    • v.27 no.3
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    • pp.290-297
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    • 2016
  • The absorbent loss due to degradation in $CO_2$ capture process using aqueous alkanol amine solution has adverse effect on the economics of overall process. The degradation causes absorbent loss, equipment corrosion, foaming, adhesive material producing and viscosity increase in operation. In this study, the degradation characteristics of $CO_2$ capture process using MEA (monoehtanolamine) under various conditions such as $O_2$ partial pressure, $CO_2$ loading and absorbent temperature. The effects of iron, which generated from the equipment corrosion, on absorbent degradation were studied using $Fe_2SO_4$ containing MEA solution. The produced gases were analyzed by FT-IR(Fourier Transform Infrared Spectrophotometer) and the specifically measured $NH_3$ concentration was used as a degradation degree of aqueous MEA solution. The experiments showed that the higher $CO_2$ loadings (${\alpha}$), $O_2$ fraction ($y_{O2}$) and reaction temperature enhanced the more degradation of aqueous MEA solution. Comparing other operation parameters, the reaction temperature most affected on the degradation. Therefore, it could be concluded that the above parameters affects on degradation should be considered for the selections of $CO_2$ absorbent and operating conditions.

Molecular discrimination of Panax ginseng cultivar K-1 using pathogenesis-related protein 5 gene

  • Wang, Hongtao;Xu, Fengjiao;Wang, Xinqi;Kwon, Woo-Saeng;Yang, Deok-Chun
    • Journal of Ginseng Research
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    • v.43 no.3
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    • pp.482-487
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    • 2019
  • Background: The mixed-cultivation of different Panax ginseng cultivars can cause adverse effects on stability of yield and quality. K-1 is a superior cultivar with good root shape and stronger disease resistance. DNA markers mined from functional genes are clearly desirable for K-1, as they may associate with major traits and can be used for marker-assisted selection to maintain the high quality of Korean ginseng. Methods: Five genes encoding pathogenesis-related (PR) proteins of P. ginseng were amplified and compared for polymorphism mining. Primary, secondary, and tertiary structures of PR5 protein were analyzed by ExPASy-ProtParam, PSSpred, and I-TASSER methods, respectively. A coding single nucleotide polymorphism (SNP)-based specific primer was designed for K-1 by introducing a destabilizing mismatch within the 3' end. Allele-specific polymerase chain reaction (PCR) and real-time allele-specific PCR assays were conducted for molecular discrimination of K-1 from other cultivars and landraces. Results: A coding SNP leading to the modification of amino acid residue from aspartic acid to asparagine was exploited in PR5 gene of K-1 cultivar. Bioinformatics analysis showed that the modification of amino acid residue changed the secondary and tertiary structures of the PR5 protein. Primer KSR was designed for specific discrimination of K-1 from other ginseng cultivars and landraces. The developed real-time allele-specific PCR assay enabled easier automation and accurate genotyping of K-1 from a large number of ginseng samples. Conclusion: The SNP marker and the developed real-time allele-specific PCR assay will be useful not only for marker-assisted selection of K-1 cultivar but also for quality control in breeding and seed programs of P. ginseng.

Effects of Mg Addition to Cu/Al2O3 Catalyst for Low-Temperature Water Gas Shift (LT-WGS) Reaction

  • Zakia Akter Sonia;Ji Hye Park;Wathone Oo;Kwang Bok Yi
    • Clean Technology
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    • v.29 no.1
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    • pp.39-45
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    • 2023
  • To investigate the effects of Mg addition at different aging times and temperatures, Cu/MgO/Al2O3 catalysts were synthesized for the low-temperature water gas shift (LT-WGS) reaction. The co-precipitation method was employed to prepare the catalysts with a fixed Cu amount of 30 mol% and varied amounts of Mg/Al. Synthesized catalysts were characterized using XRD, BET, and H2-TPR analysis. Among the prepared catalysts, the highest CO conversion was achieved by the Cu/MgO/Al2O3 catalyst (30/40/30 mol%) with a 60 ℃ aging temperature and a 24 h aging time under a CO2-rich feed gas. Due to it having the lowest reduction temperature and a good dispersion of CuO, the catalyst exhibited around 65% CO conversion with a gas hourly space velocity (GHSV) of 14,089 h-1 at 300 ℃. However, it has been noted that aging temperatures greater or less than 60 ℃ and aging times longer than 24 h had an adverse impact, resulting in a lower surface area and a higher reduction temperature bulk-CuO phase, leading to lower catalytic activity. The main findings of this study confirmed that one of the main factors determining catalytic activity is the ease of reducibility in the absence of bulk-like CuO species. Finally, the long-term test revealed that the catalytic activity and stability remained constant under a high concentration of CO2 in the feed gas for 19 h with an average CO conversion of 61.83%.

Study on The Regulation on Poisonous Medicinal Herbs (독성 한약재의 법적 규제에 관한 연구)

  • Kweon, Kee-Tae
    • The Korean Society of Law and Medicine
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    • v.11 no.1
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    • pp.271-296
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    • 2010
  • Objective: Poisonous Medicinal herbs can be considered as a risk factor to public health unless they are prescribed by Doctor of traditional Korean medicine. The proper method to manage them should be prepared to prevent risk factors caused by misuse and abuse of the poisonous medicinal herbs and enhance public health. Methods: In this dissertation (paper), the definition, scope, management status, data about pharmacology and toxicity and media release regarding adverse reaction were understood after organizing documents, laws and regulations concerning poisonous medicinal herbs. Also, management methods are suggested by analyzing related examples and regulations in China, Japan and Hong Kong, where the use of herbal medicine is general. Results: Methods for items for poisonous medicinal herbs, safety information management, management based on standardization of traditional processing methodology and reorganization and revision of related laws and regulations are established. Conclusion: Proper laws and regulations are not yet established to manage poisonous medicinal herbs in Korea. In this regard, it is urgent to establish laws and regulations which can apply independently. The purpose of the laws and regulations should be to enhance management of poisonous medicinal herbs and prevent incidence of addiction and death, improving the public health.

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Modeling of Water Temperature in the Downstream of Yongdam Reservoir using 1-D Dynamic Water Quality Simulation Model (1차원 동적수질모형을 활용한 용담댐 하류하천의 수온변동 모의)

  • Noh, Joonwoo;Kim, Sang-Ho;Shin, Jae-Ki
    • Journal of Korean Society on Water Environment
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    • v.26 no.2
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    • pp.356-364
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    • 2010
  • The chemical and biological reaction of the aquatic organism is closely related with temperature variation and water temperature is one of the most important factors that should be considered in establishing sustainable reservoir operation scheme to minimize adverse environmental impacts related with dam construction. This paper investigates temperature variation in the downstream of Yongdam Reservoir using sampled data collected from total 8 temperature monitoring stations placed along the main river and the major tributaries. Using KoRiv1, 1-dimensional dynamic water quality simulation model, temperature variation in the downstream of Yongdam Reservoir has been simulated. The simulated results were compared with sampled data collected from May 15 to August 1 2008 by applying two different temperature modeling schemes, equilibrium temperature and full heat budget method. From the result of statistical analysis, seasonal temperature variation has been simulated by applying the equilibrium temperature scheme for comparison of the difference between the reservoir operation and the natural conditions.

SIRAS (ALBIZIA LEBBECK (L.) BENTH.) AND ITS MEDICINAL USES IN UNANI MEDICINE- A REVIEW

  • Waseem, Azma;Jamal, Anwar;Ahmad, Waseem;Fazil, Mohammad
    • CELLMED
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    • v.10 no.2
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    • pp.12.1-12.5
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    • 2020
  • Higher incidences of adverse reaction associated with the prolonged use of synthetic drugs has once again increased the faith of humans in the traditional systems of medicine and motivated them to return back towards the clinical proven remedies for the treatment. It is also true that number of modern medications used in the present scenario, were developed from various plants. In Unani System of medicine, numerous herbal drugs are mentioned for medicinal purpose. Siras (Albizia lebbeck (L.) Benth.) is one of them. It is found all over India. Almost all parts of this plant are used for the treatment of ailments such as migraine, conjunctivitis, diarrhea, jaundice, skin problems, asthma etc. Many chemical constituents have been isolated from Albizia lebbeck such as lebbekannin, echinocystic acid, flavonoids, Linoleic acid, saponins etc. This review highlights the medicinal properties and therapeutic uses of Albizia lebbeck and scientific studies conducted on the drug in human and animal models that will provide the further research direction.

Four Cases of Scrub Typhus Treated with Azithromycin in Children (소아에서 발생한 쯔쯔가무시 열에서 Azithromycin 치료 완치 4례)

  • Kim, Eun Jung;Lee, Chang Yoo;Oh, Yeon Gyun;Yun, Hyang Suk;Kim, Jong Duck
    • Clinical and Experimental Pediatrics
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    • v.46 no.2
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    • pp.188-191
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    • 2003
  • Tsutsugamushi fever is a serious febrile disease outwardly similar to malaria and various arboviral infections. The endemic area is Asia-Pacific. This disease are generally associated with disturbed habitats favoring large populations of vector larval trombiculid mites. Therapy with tetracycline, chloramphenicol or ciprofloxacin is currently recommanded. Unfortunately these drugs is suboptimal for children and pregnant women. Recently, azithromycin has been proven to be effective in therapy of scrub typhus. There is no evidence that azithromycin causes adverse reaction to developing fetus or children. We report four cases of tsutsugamushi fever in children successfully treated with azithromycin. This is the first report describing clinical application of azithromycin to tsutsugamushi fever in Korean children.

The Utilization of Waste Seashell for High Temperature Desulfurization

  • Kim, Young-Sik;Hong, Sung-Chul
    • Journal of Environmental Health Sciences
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    • v.36 no.2
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    • pp.136-140
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    • 2010
  • The integrated gasification combined cycle (IGCC) is one of the most promising proposed processes for advanced electric power generation that is likely to replace conventional coal combustion. This emerging technology will not only improve considerably the thermal efficiency but also reduce or eliminate the environmentally adverse effects normally associated with coal combustion. The IGCC process gasifies coal under reducing conditions with essentially all the sulfur existing in the form of hydrogen sulfide ($H_2S$) in the product fuel gas. The need to remove $H_2S$ from coal derived fuel gases is a significant concern which stems from stringent government regulations and also, from a technical point of view and a need to protect turbines from corrosion. The waste seashells were used for the removal of hydrogen sulfide from a hot gas stream. The sulphidation of waste seashells with $H_2S$ was studied in a thermogravimetric analyzer at temperature between $600^{\circ}C$ and $800^{\circ}C$. The desulfurization performance of the waste seashell sorbents was experimentally tested in a fixed bed reactor system. Sulfidation experiments performed under reaction conditions similar to those at the exit of a coal gasifier showed that preparation procedure and technique, the type and the amount of seashell, and the size of the seashell affects the $H_2S$ removal capacity of the sorbents. The pore structure of fresh and sulfided seashell sorbents was analyzed using mercury porosimetry, nitrogen adsorption, and scanning electronmicroscopy.

A Comparative Study Between On-Pump and Off-Pump Coronary Artery Bypass Grafting on Clinical Outcomes

  • Moon Seong-Min;Choi Seok-Cheol
    • Biomedical Science Letters
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    • v.10 no.3
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    • pp.237-243
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    • 2004
  • In recent, many cardiac centers have preferred off-pump coronary artery bypass grafting (CABG) to on-pump CABG to prevent the adverse effects of cardiopulmonary bypass. The present study was performed to prove beneficial effects of off-pump CABG. Sixty adult patients scheduled for elective CABG were randomly assigned to On-pump group (n=30) or Off-pump group (n=30). Arterial blood samples were drawn before and after the operation (Pre-OP and Post-OP, respectively) for measuring CBC, prothrombin time, activated thromboplastine time, blood gas analysis, creatine kinase-MB (CK-MB) level, and lactate dehydrogenase (LDH) level. Perioperative parameters including heparin and protamine usages, complications, blood components usages, blood loss, ventilation and ICU-staying time, and hospitalization were also evaluated. Platelet count at Post-OP was high in Off-pump group whereas CK-MB and LDH levels were low compared with On-pump group. Off-pump group had significantly lower heparin and protamine usages, lower total leukocyte count, higher hematocrit and hemoglobin levels, less blood loss, lower usages of blood components, shorter ventilation and ICU-staying time, and lower incidence of pleural effusion than On-pump group. Other variables did not significantly differ between two groups. These results showed that Off-pump CABG was a satisfactory technique with less inflammatory reaction, less cardiac damage, less postoperative complications, and less cost.

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