• Title/Summary/Keyword: adverse effects

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The Adverse Effects of Radiotherapy and Its Management in the Hospice and Palliative Care Patients (호스피스.완화의료 환자에게 적용한 방사선 치료의 부작용과 대처법)

  • Lee, Soon-Sin;Park, Young-Jin;Han, Seong-Ho;Park, Joo-Sung
    • Journal of Hospice and Palliative Care
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    • v.14 no.2
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    • pp.61-70
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    • 2011
  • Recent advances in techniques and strategies use to detect cancer in its early stages and to treat it effectively has the survival rate of cancer patients and the number of long-term cancer survivors continually increasing. Unfortunately, many cancer survivors are at risk for various late and long-term effects of cancer treatments including the radiotherapy. Long-term cancer survivors can be also seen for a hospice and palliative care because of cancer recurrence and they are at risk of delayed reactions to radiotherapy. So, the understanding and knowledge of radiation reactions is required for the proper medical diagnosis, management, and coordination of the potential reactions that may occur in these care setting. In effort to increase the survival rate in cancer patients and to decrease the adverse effects of cancer treatment, many clinical studies have been and continue to be conducted. The efforts of these studies have thus resulted in the advancement of cancer treatments. Regrettably, the overall interest in how to manage adverse effects of cancer treatment such as radiotherapy appears seemingly low in clinical practice and its advanced studies as a whole are delayed and deficient. It is imperative that the medical community show an enthusiastic interest in the aftercare of cancer patients and cancer survivors in order to create a complementary integrative approach that will eliminate radiotherapy related pain/discomfort or illness in hospice and palliative care settings.

SUPPLEMENTATION OF EARLY WEANED CALVES WITH COMBINATIONS OF RUMEN MODIFIERS, COTTONSEED MEAL AND MOLASSES AND TREATMENT WITH AVERMECTIN B1

  • Burns, B.M.;Lindsay, J.A.;Hobbs, K.J.;Reid, D.
    • Asian-Australasian Journal of Animal Sciences
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    • v.3 no.4
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    • pp.337-341
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    • 1990
  • An investigation was conducted to determine whether the rumen modifiers lasalocid and avoparcin, when included in molasses/urea based supplements, enhanced liveweight performance, in early weaned calves. As part of the study the broad-spectrum parasiticle Avermectin B1 was given to the calves to assess any undesirable side effects on animals of less than four months of age. There were no significant (p>0.05) liveweight responses to supplementation when the rumen modifiers lasalocid and avoparcin were included in supplement rations. Lasalocid reduced supplement intake, however, it had no adverse effect on liveweight gain. Avoparcin substantially improved growth when cottonseed meal was included in the ration. Weaners treated with Avermectin B1 tended to show a greater liveweight gain than untreated weaners during the experiment (p<0.10) and no adverse side effects were noted.

A Case of Subclinical Hyperthyroidism Treatment with Herbal Medicine (한약 단독치료로 호전된 불현성 갑상선기능항진증 증례 보고)

  • Jin, Dong-eun;Kim, Seok-woo;Shin, Hyeon-cheol
    • The Journal of Internal Korean Medicine
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    • v.39 no.4
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    • pp.831-838
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    • 2018
  • Objective: This study was performed to evaluate the effects of herbal medicine on an elderly patient with subclinical hyperthyroidism who could not use antithyroid medication due to an adverse reaction to methimazole. Methods: Herbal medicine was administered and a thyroid function test was used to evaluate the effects of the treatment. Results: After treatment with herbal medicine and therapy, the patient showed improvements in TSH levels. Conclusion: This case suggested that herbal medicine can be used for patients who have adverse reactions to antithyroid medication; however, additional studies with more patients are required for verification of this finding.

다중계통의 점검 및 보수로 인한 역효과(Adverse Effects)를 고려한 점검방법별 시스템 이용불능도(Unavailability) 분석

  • 유영우;정창현;제무성;정대욱;류용호
    • Proceedings of the Korean Nuclear Society Conference
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    • 1996.05b
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    • pp.562-569
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    • 1996
  • 원자력 발전소 기기들에 대한 점검주기와 점검방법은 기술지침서(Tech. Spec)의 점검요건(SR)에 명시되어 있는데 가압경수로(PWR) 원전의 경우 다중계통 기기 점검은 교번시험(Staggered Test) 방법으로 점검하도록 되어 있다. 그러나 그 동안의 원전 운전경험에 의하면 기기 점검 및 보수로 인하여 기기 마모. 발전소 정지. 운전원의 부담감, 방사선 피폭 등의 역효과(Adverse Effects)가 있는 것으로 알려져 있다. 본 연구에서는 다중계통(Multi-redundancy System)중 2/4 시스템에 대한 점검방법별 이용불능도(Unavailability)를 해석적 방법으로 구하고 점검 및 보수로 인한 기기 마모 역효과를 모델링하여 점검방법별로 적용하고 비교 분석하였다.

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Novel Biocide Controls Biofilm Formation without Adversely Affecting the Papermaking Process

  • Bharti, Shashank;Kim, Hyung-Ju;Kim, Ik-Dong
    • Proceedings of the Korea Technical Association of the Pulp and Paper Industry Conference
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    • 2006.06a
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    • pp.67-71
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    • 2006
  • Strong oxidizing biocides are commonly used to control biofilm formation in alkaline papermaking systems. However, paper streams contain many substances that react with or consume oxidizers (e.g., fiber and starch, Therefore, to achieve effective microbiological control, the oxidizer must be overfed to overcome the effect of these substances. When dosed in this manner, the oxidizer can cause many unwanted reactions and adverse side effects, including the consumption of costly papermaking additives increased corrosion rates, and reduced felt life. Some oxidizers also contribute to the formation of halogenated organic compounds. When used for biofilm control, strong oxidizers can cause more problems than they remedy. A patented biocide that effectively controls biofilm without the adverse side effects associated with strong oxidizing biocides is available from Hercules. $Spectrum^{(R)}$ XD3899 Ammonium Bromide Technology, which can be described as a mild oxidizer, is currently used on more than 300 machines globally and has resulted in numerous production and/or machine efficiency records since its introduction in 2001.

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Development of EV Charging Scheme Considering Distributed Generation and Energy Storage System (분산전원과 ESS를 고려한 전기 자동차 충전 기법 개발)

  • Sim, Bo-Seok;Kim, Jun-Hyeok;Lee, Soon-Jeong;Kim, Chul-Hwan
    • Proceedings of the KIEE Conference
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    • 2015.07a
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    • pp.521-522
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    • 2015
  • Many countries concern about environmental problems. Therefore, they have made regulation for mandatory reduction of greenhouse gases. Electric Vehicles(EVs) are one of the most effective counterproposals for it. EVs are usually charging for it by using actual distribution system of the Korea Electric Power Corporation(KEPCO). However, it could cause adverse effects such as increase of the power demand and voltage variation on the distribution system. To reduce adverse effects for demand power side, in this paper, charging for EVs by using PV(Photovolatic Power Generation) connected with ESS(Energy Storage System) are modeled by using Electro Magnetic Transient Program(EMTP). And then, the simulation results are compared with EVs that are connected to the distribution system of KEPCO for using charge.

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Coating defects in polymer-coated drug-eluting stents

  • Bedair, Tarek M.;Cho, Youngjin;Park, Bang Ju;Joung, Yoon Ki;Han, Dong Keun
    • Biomaterials and Biomechanics in Bioengineering
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    • v.1 no.3
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    • pp.131-150
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    • 2014
  • Vascular stenting has a great attention as a treatment for coronary arteries diseases as compared with percutaneous balloon angioplasty. In-stent restenosis and thrombosis are side effects resulting from using bare metal stent (BMS). Employing platelet therapy allowed to reduce the rate of thrombosis, however, the rate of restenosis remains a major problem. In 2002, drug-eluting stents (DESs) were introduced as an effort to reduce the restenosis. The commercially available DESs continue to suffer from coating defects that might lead to a series of adverse effects. Most importantly, multiple concerns remain regarding the polymer coating integrity on metal surfaces or the relation of polymer irregularities to longterm adverse events.

Current use of growth hormone in children (성장호르몬 치료의 최신 지견)

  • Shin, Choong Ho
    • Clinical and Experimental Pediatrics
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    • v.49 no.7
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    • pp.703-709
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    • 2006
  • Since the advent of growth hormone(GH), children with a wide variety of growth disorders have received GH treatment. In GH deficiency(GHD), Turner syndrome, chronic renal failure, children born small for gestational age, Prader-Willi syndrome, and idiopathic short stature, the therapeutic effects and safety profile of GH are reviewed. GH therapy has been clearly shown to improve height velocity and final adult height in a variety of pediatric conditions in which growth is compromised irrespective of GHD. Early initiation and individualization of GH treatment has the potential to normalize childhood growth. The supra-physiological doses of GH have been shown to increase height velocity during childhood and final height in non-GHD conditions. Adverse events during GH therapy are uncommon and often not drug related. However continued surveillance into adult life is crucial, especially in children receiving supra-physiological doses or whose underlying condition increases their risk of adverse effects.

Nutritional Modulation of Resistance and Resilience to Gastrointestinal Nematode Infection - A Review

  • Walkden-Brown, Stephen W.;Kahn, Lewis P.
    • Asian-Australasian Journal of Animal Sciences
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    • v.15 no.6
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    • pp.912-924
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    • 2002
  • Disease susceptibility is linked to nutritional status for a wide range of human and animal diseases. Nutritional status can influence both resistance (ability to resist the pathogen) and resilience (ability to tolerate or ameliorate the effects of the pathogen). This review focuses on the nutritional modulation of gastro-intestinal nematode infection in domestic ruminants, primarily sheep. It highlights the duality of the adverse consequences of infection on host nutritional status and the adverse consequences of poor host nutritional status on resistance to infection. Central to both phenomena is the complex, gut-based immune response to gastrointestinal nematode infection. The potential for strategic nutritional supplementation to enhance host resistance and resilience is reviewed together with recent findings on responses to increased ME supply, and long term effects on host immunity of short term protein supplementation.

Acute kidney injury caused by administration of zaltoprofen in a cat

  • Baek, Woon-Bum;Kim, Hak-Hyun;Kang, Byeong-Teck;Kang, Ji-Houn;Yang, Mhan-Pyo
    • Korean Journal of Veterinary Research
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    • v.57 no.1
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    • pp.55-57
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    • 2017
  • A 5-year-old, 2.7 kg, spayed female Scottish Fold cat presented with hematemesis after administration of oral zaltoprofen, a non-steroidal anti-inflammatory drug, by the owner. Diagnostic imaging and blood analyses indicated development of acute kidney injury (AKI) resulting from zaltoprofen ingestion. To correct dehydration and anemic conditions, the cat received intravenous fluid therapy with whole blood transfusion and peroral N-acetylcysteine. Clinical signs resolved, but persistent azotemia was unresolved indicating that AKI could progress to chronic kidney disease. This case suggests that although zaltoprofen may have low adverse effects on humans, administration of zaltoprofen in cats can have serious adverse effects.