• Journal of Radiation Protection and Research
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• v.46 no.3
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• pp.98-105
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• 2021

Background: In recent events of the coronavirus disease 2019 (COVID-19) pandemic, computed tomography (CT) scans are being globally used as a complement to the reverse-transcription polymerase chain reaction (RT-PCR) tests. It will be important to be aware of major organ dose levels, which are more relevant quantity to derive potential long-term adverse effect, for Korean pediatric and adult patients undergoing CT for COVID-19. Materials and Methods: We calculated organ dose conversion coefficients for Korean pediatric and adult CT patients directly from Korean pediatric and adult computational phantoms combined with Monte Carlo radiation transport techniques. We then estimated major organ doses delivered to the Korean child and adult patients undergoing CT for COVID-19 combining the dose conversion coefficients and the international survey data. We also compared our Korean dose conversion coefficients with those from Caucasian reference pediatric and adult phantoms. Results and Discussion: Based on the dose conversion coefficients we established in this study and the international survey data of COVID-19-related CT scans, we found that Korean 7-year-old child and adult males may receive about 4-32 mGy and 3-21 mGy of lung dose, respectively. We learned that the lung dose conversion coefficient for the Korean child phantom was up to 1.5-fold greater than that for the Korean adult phantom. We also found no substantial difference in dose conversion coefficients between Korean and Caucasian phantoms. Conclusion: We estimated radiation dose delivered to the Korean child and adult phantoms undergoing COVID-19-related CT examinations. The dose conversion coefficients derived for different CT scan types can be also used universally for other dosimetry studies concerning Korean CT scans. We also confirmed that the Caucasian-based CT organ dose calculation tools may be used for the Korean population with reasonable accuracy.

• The Journal of the Korean dental association
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• v.55 no.9
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• pp.617-624
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• 2017

Objective: To compare the electromyographic activity of masseter and temporal muscles between bruxers and nonbruxers in adult and adolescent patients. Material and Methods: The samples composed of the surface electromyography (EMG) recordings obtained from the orthodontic patients. Sixty-eight patients who had bruxsim habit (43 female and 25 male) were divided into four groups according to their age and gender. Control groups consisted of 79 patients who had not bruxism habit. EMG of the masseter muscle and anterior temporal muscle were recorded before treatment in clenching at maximum intercuspation. The ratio of temporal and masseter muscle activity (T/M ratio) was compared between bruxers and nonbruxers in adult and adolescent patients. Results: EMG of masseter muscle and temporal muscle were significantly higher in adult male bruxism group than control. T/M ratio in adult male bruxism group was significantly lower than in adult male nonbruxism group. However, there was no significant difference in T/M ratio between adolescent bruxism group and adolescent nonbruxism group. Conclusions: The balance in the activity of the masseter and temporal muscles may not differ between bruxers and nonbruxers during adolescent periods. However, in adult period, the masseter muscle activity against temporal muscle is greater in males with bruxism habit compared to non-bruxer.

• Journal of Yeungnam Medical Science
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• v.21 no.1
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• pp.67-73
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• 2004

Background: A ureteropelvic junction (UPJ) obstruction is a congenital anomaly commonly afflicting the pediatric population. However, it occurs more frequently in adults than is generally appreciated. To assess their characteristics, we have here compared and analyzed the clinical manifestations, causes, and outcomes of UPJ obstruction found in children and adults. Materials and Methods: 102 patients (118 renal units) out of 182 patients (218 renal units), with diagnosed UPJ obstruction, were available for follow up. The follow-ups were retrospectively reviewed to determine the presenting symptoms, treatments, and clinical outcomes. Patients who were younger than 18 years of age were assigned to the pediatric group (44 patients), others the adult group (58 patents). Results: The majority of the patients presented with flank pain (pediatric group: 68%, adult group: 76%). The majority of patients underwent a pyeloplasty (pediatric group: 50.9%, adult group: 62.3%). And the major cause of the UPJ obstruction was an intrinsic stenosis (pediatric group: 53%, adult group: 56%). Conclusion: The prevalence of bilateral UPJ obstruction in adults is evidently less prevalent than in pediatrics, and despite the late diagnosis, the surgical outcome is similar. A further investigation of UPJ obstruction will lead us to a more comprehensive understanding of the disease.

• YAKHAK HOEJI
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• v.45 no.2
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• pp.153-160
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• 2001

This research developed an intravenous (IV) vancomycin dosing nomogram based on the clinical pharmacokinetic data of Korean adult patients. Total 99 pairs of steady-state peak and trough serum concentrations of vancomycin were obtained from 73 adult patients in a tertiary general hospital. Serum vancomycin concentrations were determined to assess the appropriateness of initial vancomycin dosing. Only 47.2% of the cases were within therapeutic range. To characterize the clinical pharmacokinetics (PK) of vancomycin, PK parameters including elimination rate constant ( $K_{e}$) half-life( $T_{1}$2/), clearance (C $l_{van}$), volume of distribution ( $V_{d}$) were calculated by using one-compartment, first order pharmacokinetic equations. PK parameters were evaluated based on the differences of patients'renal function and age. Regression analysis showed a significant correlation between C $l_{van}$ and $C_{cr}$ (C $l_{van}$ = -1.89+0.914 $C_{cr}$ , r=0.763) and between $K_{e}$ and $C_{cr}$ , ( $K_{e}$=-0.0037+0.00139 $C_{cr}$ =0.724). The relationship between $K_{e}$ and $C_{cr}$ , and the mean $V_{d}$ were utilized for developing the nomogram to individualize the initial dosing regimen of vancomycin for the patients with various degrees of renal functions. The nomogram may be used as an efficient tool to determine safe and effective doses of vancomycin for the Korean adult patients.nts.nts.nts.s.nts.

• Journal of Korean Gerontological Nursing
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• v.20 no.3
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• pp.204-216
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• 2018

Purpose: The purpose of this study was to examine effects of a muscle strength reinforcement exercise program (MSREP) for older adult patients with hemodialysis (OAPHD) which was designed to improve health status and quality of life of these older adult patients. Methods: Participants were 40 patients with OAPHD: 20 in the experimental group and 20 in the control group. MSREP was conducted with the experimental group for 12 weeks at H geriatric hospital. An assessment was done to determine effects on physical performance, inflammation index, fatigue, muscle strength and quality of life. Short physical performance battery, C-Reactive Protein (CRP), visual analog scale for fatigue, object lifting' proposed by the Life Options Rehabilitation Advisory Council, sit-to-stand test, and quality of life index were used to gather data. Results: Between the 2 groups there was no significant difference in scores for physical performance, fatigue or quality of life. However, the 2 groups showed significant difference in CRP values and muscle power scores on post-test. Conclusion: Findings provide evidence for the potential utility of education for older adult patients with hemodialysis. Also, this program could allow these patients to increase muscle strength, and contribute to achieving better health conditions in OAPHD care.

• The Journal of Korean Physical Therapy
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• v.14 no.3
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• pp.129-135
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• 2002

The aim of this study is to present the basic reference data of age and specipic gait parameters for Hemiplegia Patients. The basic gait parameters were extracted from 30 Adult Hemiplegia Patients and 30 normal adult, 50 to 60 years of age using VICON 512 Motion Analyzer. The results were as follows; 1) The mean Cadence of the adult to the hemiplegia were $108.50\pm11.67$ steps/min, to $77.57\pm22.71$ steps/min. 2) The mean Walking Speed of the adult to the hemiplegia were $1.07\pm0.18m/s$, to $0.44\pm0.14m/s.$. 3) The mean Stride Length of the adult to the hemiplegia were $1.17\pm0.12m$, to $0.69\pm0.21m.$ 4) The mean maximal angles of joint on the pelvic tilt for different adult or hemiplegia Were $7.60\pm3.91.,\;to\;9.63\pm4.94.\;(P<0.05)$ 5) The mean maximal angles of joint on the hip flexion motion for different adult or hemiplegia were $29.53\pm5.03.,\;to\;25.30\pm9.94.\;(p<0.05)$ 6) The mean maximal angles of joint on the knee flexion motion for different adult or hemiplegia were $56.36\pm5.81.,\;to\; 41.64\pm17.21.(P<0.05)$ 7) The mean maximal angles of joint on the ankle dorsiflexion motion for different adult or hemiplegia were $16.65\pm2.72.,\;to\;16.53\pm7.45$(P>0.05) 8) The mean maximal angles of joint on the ankle plantarflexion motion for different adult or hemiplegia were $7.11\pm5.42.,\;to\;2.81\pm6.14.$(p<0.05)

• Journal of Periodontal and Implant Science
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• v.34 no.4
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• pp.723-731
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• 2004

Helicobacter pylori(H. pylori) has been associated with the cause of chronic gastritis, peptic ulcers and gastric cancer. Although it may be transmitted through the oral cavity, it is unknown whether the oral cavity acts as a reservoir of H. pylori. The purpose of this study was to investigate the mode of detection of H. pylori in oral cavity of adult periodontitis patients with plaque and periodontal pocket which atmosphere is grown well H. pylori. We analysed detection rate of H. pylori in saliva and subgingival plaques of 17 adult periodontitis patients without symptoms of gastroduodenal disease by nested PCR. Samples tested comprised saliva and subgingival plaques from central incisor, 1st premolar and 1st molar. H. pylori DNA was not identified in saliva from all patients. The detection rate in subgingival plaque from incisors, premolars and molars was 5.9%, 5.9% and 17.7%, respectively. In conclusion, the dental plaque and periodontal pocket (especially, of molars) in adult periodontitis can be favorable reservoir of H. pylori and may be the source of infection and transmission of H. pylori.

• Archives of Plastic Surgery
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• v.38 no.6
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• pp.755-760
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• 2011

Purpose: Correction of cleft lip nose deformity (CLND) in adulthood is different from one in childhood. Usually correction of CLND is final surgery for adult patient who has cleft lip, so many things have to be considered for correction. Of course, it is different from common rhinoplasty, either. The adult patients can be corrected by complete rhinoplasty with various techniques. To recognize how rhinoplasty techniques was used for correction of CLND, authors analyzed detailed techniques which were selected in the adult patients for 10 years and reviewed comprehensive operation. Methods: A retrospective review was conducted involving 64 patients with CLND who underwent surgery and aged after 14 years at operation between 2001 and 2010. Detailed techniques were investigated by medical record review and classified according to incision, septoplasty, osteotomies, correction of vault, tip plasty and etc. Results: Except one, all patients were performed open rhinoplasty. 49 patients were performed septoplasty. 33 patients were performed complete rhinoplasty with osteotomies. Hump nose correction was performed for 10 patients. Dorsal augmentation was performed for 8 patients. And all patients were performed tip plasty. Tip plasty using suture technique was performed for 58 patients and graft was performed for 48 patients. Conclusion: Correction of CLND in adult is one of the most challenging and varied operation of plastic surgery. In this study, the majority of patients were performed complicated and delicated procedures. It seems to be because patient's demand level has been elevated and rhinoplasty procedures have been advanced. This study may help to planning of CLND correction.

• Journal of The Korean Society of Integrative Medicine
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• v.8 no.2
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• pp.121-130
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• 2020

Purpose : The objective of the current study was to evaluate the impact of the Computer-Based Cognitive Rehabilitation Program (CoTras) on the cognitive function and daily living activities of elderly and adult stroke patients. Methods : Twenty stroke patients were divided into two groups comprising 10 elderly stroke patients and 10 adult stroke patients. The CoTras was applied as the intervention for 30 minutes at a time, three times a week, for nine weeks (i.e., a total of 27 times), to both groups. The Neurobehavioral Cognitive Status Examination was used to assess cognitive function, and the Functional Independence Measure was utilized to evaluate daily living activities, prior to, during, and after the intervention. Results : The CoTras was demonstrated to have a statistically significant and positive effect on the cognitive function and daily living activities of stroke patients. However, the effect of the program on the restoration of weight-shifting capacity, as a component of the daily living activities of stroke patients, was without statistical significance. The program had a greater influence on improving the cognitive function and daily living activities of elderly stroke patients than adult stroke patients. Conclusion : This study makes a meaningful contribution to the literature on the topic as the intervention was demonstrated to lead to a more significant recovery of cognitive function and daily living activities in elderly stroke patients, compared to adult patients. Therefore, it is proposed that the CoTras should be used as a clinical intervention for elderly stroke patients. Future studies that evaluate the application of the CoTras, along with other occupation-based intervention programs, are warranted.

• Journal of Clinical Nutrition
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• v.10 no.2
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• pp.38-44
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• 2018

Purpose: Parenteral nutrition (PN) is known to provide therapeutic beneficial improvements in malnourished patients for whom enteral nutrition is not feasible. The objective of this study was to investigate the current clinical characteristics and utilization of PN in Korea. Methods: We analyzed the Health Insurance Review Agency National Inpatients Sample database from 2014 to 2016, which included 13% of all hospitalized patients in Korea. Adult patients aged 20 years or older and receiving premixed multi-chamber bag containing PN were included for this study. Patient characteristics, admission type, primary diagnosis, and hospital demographics were evaluated. SAS version 9.4 was used for data analysis. Results: From 2014 to 2016, 149,504 patients received premixed PN, with 226,281 PN prescriptions being written. The mean patient age was 65.0 years, and 81,876 patients (54.8%) were male. Premixed 3-chamber bag and 2-chamber bag PN solutions were utilized in 131,808 (88.2%) and 32,033 (21.4%) patients, respectively. The number of patients hospitalized through the emergency department were 70,693 (47.3%), whereas 43,125 patients (28.8%) were administered PN in intensive care units. In the adult PN patients, the highest primary diagnosis was malignant neoplasm of the stomach (8,911, 6.0%), followed by organism unspecified pneumonia (7,008, 4.7%), and gastroenteritis and colitis of unspecified origin (6,381, 4.3%). Overall, 34% of adult PN patients were diagnosed with malignancies, the most common being neoplasm of the stomach (17.7%), neoplasm of bronchus/lung (11.2%), neoplasm of colon (11.1%), and neoplasm of liver/intrahepatic bile ducts (10.0%). PN solutions were most frequently administered in the metropolitan area (55.0%) and in hospitals with more than 1,000 beds (23.6%). Conclusion: PN was commonly administered in older patients, with primary diagnosis of malignancy in a significant number of cases. This study is the first large-scale description of PN-prescribing patterns in real-world clinical practice in South Korea.